Penn Medicine researchers Katalin Karikó Ph.D., and Dr. Drew Weisman Ph.D., won the 2023 Nobel Prize in Medicine for their work on mRNA technology that contributed to the COVID-19 vaccine research.

Patents typically last about 20 years. The university holds at least four patents for its mRNA technology across the United States and Europe.

Researcher Karikó, an adjunct professor at Penn Medicine for 36 years, worked as a senior vice president for BioNTech between November 2013 and October 2022, according to her LinkedIn profile. She is considered an external consultant for the company as of Jan. 2, according to its website.

The COVID-19 vaccine, also known as Comirnaty, generated about $5 billion in sales in 2024.

As part of the deal, pharmaceutical giant Pfizer is expected to chip in $170 million for the Penn royalties and $364 million towards the NIH royalties owed.

As a company, BioNTech generated about $3.9 billion in revenue during 2023, down from $17.7 billion in 2022. BioNTech estimated 2024 revenue to be between $2.7 billion and $3.3 billion.

The university licensed its mRNA patents to several companies between April 2010 and August 2020, including Epicentre Technologies Corp., mRNA Biotherapeutics Inc. and Cellscript.

In 2017, BioNTech sublicensed the university mRNA technology from Cellscript and expects to keep developing more pharmaceutical medications, such as cancer treatments and flu vaccines, using the university patented technology.

Licensing revenue at the University of Pennsylvania has been a substantial revenue stream for the Philadelphia institution since the COVID-19 pandemic began.

In fiscal 2021, the university collected $300 million in license revenue. In fiscal years 2022 and 2023, the university garnered $1 billion each year. During fiscal year 2024, it reported $466 million in licensing revenue.

In May 2024, Penn Medicine researchers developed an mRNA vaccine for the H5N1 avian flu, leveraging prior COVID-19 vaccine research. The research was funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health and the Department of Health and Human Services.

The Duke University Human Vaccine Institute was awarded $7 million from the federal health agencies to conduct clinical trials in early 2025.

But for the commercialization of such research, the university relies on pharmaceutical manufacturers to license such patents and take the drug to market.

It was not immediately clear which companies, if any, have licensed the experimental avian flu technology.

Molloy undertook these actions “knowing that the organization was a designated terrorist organization and that the organization had engaged in and was engaging in terrorist activity and terrorism, ” a release from the Justice Department said in a criminal complaint.

Molloy, a citizen of both the United States and Ireland, previously served on active duty status in the U.S Army, traveled to Lebanon in August 2024 and attempted to join Hezbollah but was told by “multiple individuals that the time was not right, and that he needed to take other steps before he could join the terrorist organization,” the Justice Department release said.

Molloy continued to try to join Hezbollah while living in Upper St. Clair, Pa. and allegedly continued to communicate with members of the organization online and in Lebanon. He also expressed his hatred toward, and promoted violence against, Jewish people,” documents show.

“Molloy’s alleged animus toward Jews was also evidenced by multiple images and videos on his electronic devices and the usernames he chose for his social media and email accounts, including the username “KIKEKILLER313″ on the social media platform X. In one alleged WhatsApp exchange with a family member, Molloy agreed that his ‘master plan was to join Hezbollah and kill Jews,’” Justice Department documents show.

He is also alleged to have visited a website that showed the possible incarceration location of Robert Bowers, the man who carried out the 2018 Pittsburgh Tree of Life Synagogue shooting during which he murdered 11 Jewish worshippers. It is thought that Molloy was a Bowers sympathizer.

The indictment also says Molloy lied to FBI investigators at the Pittsburgh International Airport in October, 2024 about his contact with members of Hezbollah. He said had no current or future plans to become involved with the organization and that he had no business in, nor was he meeting with anyone, in Syria.

“These statements and representations were false because Molloy knew at that time that (1) he did have current and future plans to become involved with Hizballah and (2) Molloy travelled to Syria in furtherance of his attempts to join Hezbollah, and while in Syria, set up a meeting with an individual there,” the Justice Department release said.

Molloy faces up to 28 years in prison and a $250,000 fine if convicted on the material support and false statement charges.

One thousand pounds of Pennsylvania-made butter have formed a work of art celebrating the dairy farmers of the Keystone State and their cattle.

The Pennsylvania Farm Show unveiled its annual butter sculpture for the 2025 event on Thursday. The sculpture is called “From Moo to Marvel: Dairy Cows Power Pennsylvania.”

Conshohocken-based artists Jim Victor and Marie Pelton spent weeks sculpting a massive cow and additional smaller pieces like a wheel of cheese, a jug of milk, a barn, plants and a methane digester.

Land O’Lakes, which has a plant in Carlisle, Cumberland County, donated the butter used in the sculpture. The American Dairy Association announced the sculpture in a news release and said it highlights how waste and byproducts from cows and dairy farms can help create energy.

The methane digester, also called an anaerobic digester, takes waste products like manure, leftover frying oil, sewage and even pre-sculpted butter and converts them to biogas and solid digestate. Biogas is mostly methane and can be used by natural gas companies for heating and electricity or turned into fuel for vehicles.

Digestate can be treated and turned into fertilizer or compost for farmers’ fields.

Pelton and Victor have worked on butter sculptures together for 25 years. They spoke to CBS News Philadelphia in 2024 after the unveiling of last year’s farm show sculpture, “A Table For All,” showing a family at a dinner table with their animals.

That sculpture was placed in a methane digester and broken down into energy after last year’s Farm Show.

“It has a whole life after being a work of art,” Pelton said last year.

The latest sculpture will meet the same fate.  

While it’s still intact, you can see the sculpture up close at the Pennsylvania Farm Show, running Jan. 4-11, 2025, at the Farm Show Complex and Expo Center in Harrisburg.

In addition to this dairy art, the farm show features animal shows, sales and photo judging, various competitive cooking contests, rodeo events and much more.