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What we know about BA.2 — now the dominant cause of Covid-19 in the US | CNN

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What we know about BA.2 — now the dominant cause of Covid-19 in the US | CNN



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The extremely contagious Omicron subvariant BA.2 is now the dominant coronavirus pressure in the US, inflicting greater than half of all Covid-19 infections final week, the US Facilities for Illness Management and Prevention stated Tuesday.

The brand new numbers come from the CDC’s genomic surveillance. Primarily based on its fashions, the company says that BA.2 brought on between 51% and 59% of all new Covid-19 infections within the US the week ending March 26, up from an estimated 39% of all new infections the week earlier than.

The toughest-hit area was the Northeast, the place BA.2 brought on greater than 70% of all circumstances. The South and Mountain West noticed the fewest circumstances. BA.2 brought on barely greater than one-third of infections in these areas final week.

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Although BA.2 continues to be simply taking the stage within the US, it has had outstanding runs in lots of different elements of the world, together with Southeast Asia and the Western Pacific, and is winding down its European tour.

In response to the World Well being Group, BA.2 can be the principle explanation for Covid-19 globally, out-muscling two different Omicron lineages, BA.1 and BA 1.1, to change into the dominant pressure. Since its takeover, worldwide case counts – which had been declining because the first week of January – have been rising once more.

Within the UK, which has a extra extremely vaccinated inhabitants than the US, a mix of lifted restrictions, waning immunity and an much more contagious model of the virus have created a brand new BA.2 wave. Covid-19 circumstances, hospitalizations and deaths have been trending upward because the finish of February, and now, the weekly common of recent circumstances stands about the place it was on the finish of January.

BA.2 infections haven’t reached the peaks seen with BA.1, nonetheless. Case counts seem like leveling off within the UK, although hospitalizations and deaths are nonetheless rising.

All through the pandemic, the US has adopted the UK by about three weeks, so when circumstances started rising there, well being officers right here took discover.

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In America, BA.2 has been gaining steam because the finish of January, and case numbers have plateaued. That flattening conceals regional variations, nonetheless. In 13 states, weekly common numbers of recent circumstances are rising, they usually have stopped falling in 14 others, in line with knowledge collected by Johns Hopkins College.

It’s nonetheless not clear what this subvariant will do within the US. Even specialists don’t precisely know what to anticipate.

“We’re not immune from what occurs in Europe,” stated former CDC Director Dr. Tom Frieden, who’s now president and CEO of the nonprofit Resolve to Save Lives.

“In Europe, you see BA.2 turning into predominant and driving a resurgence, and the probability that won’t occur within the US is fairly low, actually,” Frieden stated. “I do assume a part of the explanation that we’re plateauing is that we’re about to start out going up once more.”

Frieden doesn’t assume it’s a coincidence that the US Meals and Drug Administration approved further booster photographs for Individuals who’re 50 and older on Tuesday, the identical day the CDC estimated that BA.2 was dominant.

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Nevertheless it’s anybody’s guess how excessive circumstances will go, whether or not numerous individuals will want hospital care, and whether or not the nation will proceed to see breathtaking numbers of deaths.

Most predictions about BA.2 within the US haven’t been dire.

The College of Washington’s Institute for Well being Metrics and Analysis’s Covid-19 projections, up to date final week, predict that BA.2 won’t drive one other surge within the US.

However they are saying we might even see one thing like what occurred in South Africa, the place BA.2 quietly changed its cousin BA.1 as the principle explanation for Covid-19 infections – with no rise in circumstances or deaths. As a substitute, it drew out Omicron’s descent, inflicting a protracted tail.

Michael Osterholm, who directs the College of Minnesota’s Heart for Infectious Illness Analysis and Coverage, known as the coronavirus ready recreation we play each few months “a well-recognized uncertainty.” He devoted his newest podcast to “all of us who stay confused about what the quick or intermediate future appears to be like like with Covid.”

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There are a number of the explanation why it’s exhausting to know what BA.2 could do. The CDC estimates that 37 million Individuals – about 1 in 11 – received Covid-19 over the winter, in the course of the first Omicron wave. Many extra have immunity from vaccination and boosters. So, primarily based on random blood samples, the CDC says that 95% of Individuals could now have a point of immunity from Covid-19.

Dr. Jorge Salinas, an infectious illness professional at Stanford College, calls this an immunologic wall.

“That provides us some safety towards future surges,” he stated. “Nonetheless, that wall deteriorates with time. The longer it goes after a wave or after vaccination, the larger the decay of the wall.”

Research have decided decided that BA.2 evades our vaccinations about in addition to unique Omicron did, so boosters are wanted to revive protections towards these variants. However lower than half the US inhabitants 12 and older has had a beneficial third dose.

Of best concern are adults over 65, as a result of they’re principally more likely to change into severely unwell with Covid-19. One out of three individuals over 65 within the US hasn’t had a essential third vaccine dose.

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“The actual downside is that a lot of our inhabitants is undervaccinated seniors,” Frieden stated. “That’s our Achilles heel.”

The opposite variable is discovered within the virus itself.

Omicron threw our immune defenses for a loop. It was so totally different from the coronavirus strains that got here earlier than that many individuals who’d gotten sick with Delta or different early strains discovered themselves contaminated once more.

BA.2 has about 40 amino acid adjustments from Omicron’s BA.1, making it about as totally different from its cousin as Alpha, Beta and Delta had been from one another. Some have questioned whether or not BA.2 might reinfect individuals who’d had BA.1.

A big research from Denmark means that these sorts of reinfections are doable however uncommon.

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The analysis on greater than 1.8 million infections discovered just one,739 circumstances by which individuals examined optimistic for Covid-19 twice inside a two-month window. Of these, 47 had been BA.1 infections that had been adopted by BA.2.

When researchers seemed extra intently, they discovered that these kinds of reinfections tended to occur to younger and unvaccinated individuals, principally kids. And their signs tended to be gentle.

The research was posted as a preprint, which means that it has not but been scrutinized by exterior specialists and revealed in a medical journal.

BA.2 is exceedingly contagious. Some epidemiologists have said its primary replica quantity could also be as excessive as 12, which means every sick particular person infects a median of 12 others. That will put it on par with measles, which additionally spreads via the air. The essential replica quantity for BA.1 is estimated to be about 8.

In a preprint research from Sweden, researchers measured viral ranges in swabs from the again of the nasal cavity. They discovered practically twice as a lot viral RNA in samples from BA.2 sufferers than in those that examined optimistic for BA.1, “pointing to a considerable distinction in viral load.”

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Viral hundreds had been about the identical for Delta and BA.1 infections, they stated, “whereas the rise in viral load in BA.2 circumstances was stunning.”

One other preprint research from Qatar picked up this distinction, too.

Laith Abu-Raddad, a professor of inhabitants sciences at Weill Cornell Medication-Qatar, has been learning the effectiveness of vaccines and boosters towards BA.1 and BA.2. A serious distinction between the 2 infections is an individual’s viral load, he stated.

“It’s positively method increased” with BA.2 over BA.1, he stated. His research discovered it to be “virtually 10-fold increased.”

As a substitute of going deeply into the lungs, the best way Delta did, the Omicron strains appear rather more targeted on the higher respiratory tract, the place the nostril meets the again of the throat, Abu-Raddad stated.

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He thinks that as a result of the an infection concentrates there, that additionally helps it unfold effectively when individuals discuss, cough or sneeze.

Maybe one brilliant spot within the BA.2 image could also be severity.

Though research in animals have instructed that BA.2 an infection wasn’t totally gentle, knowledge on human infections from the UK, Denmark and South Africa reveals that BA.2 isn’t extra more likely to end in hospitalization in comparison with BA.1.

This week, the UK Well being Safety Company up to date its knowledge on vaccine effectiveness towards BA.2. As much as 14 weeks, boosters had been nonetheless 90% efficient at stopping extreme illness in individuals over the age of 65, pointing to an necessary method to ensure BA.2 doesn’t lay us low.

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Trump names Treasury adviser from first term to chair economic panel

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Trump names Treasury adviser from first term to chair economic panel

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Donald Trump has tapped Stephen Miran, an economist who served during his first term, to chair his Council of Economic Advisers.

With the nomination, the president-elect is seeking to elevate to a White House economic post not only a critic of Federal Reserve chair Jay Powell but one who has accused the Biden administration of manipulating the economy and “usurping” the central bank’s role.

“Steve will work with the rest of my Economic Team to deliver a Great Economic Boom that lifts up all Americans,” Trump said in a statement on Sunday.

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Miran was a senior adviser for economic policy at the Treasury department in the first Trump administration.

Currently a senior strategist at hedge fund Hudson Bay Capital Management, he said he was honoured. “I look forward to working to help implement the President’s policy agenda to create a booming, noninflationary economy that brings prosperity to all Americans!” he posted on X.

The White House Council of Economic Advisers is a three-person group that advises the president on economic policy.

Trump has threatened US trading partners, vowing to impose sweeping tariffs, including 25 per cent levies on goods from Mexico and Canada and 10 per cent on China’s imports, on his first day in office.

On the campaign trail, Trump vowed to impose blanket levies of 20 per cent on all US imports, as well as tariffs of 60 per cent on those from China, suggesting his second-term policies could be more protectionist and disruptive to the global economy and markets than his first.

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The president-elect has also pledged to renew tax cuts he enacted during his first spell in the White House.

Earlier this year, Miran co-wrote a paper accusing Biden’s Treasury department of manipulating the economy during the election, arguing the government’s dependence on short-term debt amounted to “stealth quantitative easing and impedes the Fed’s ability to fight inflation.

“By adjusting the maturity profile of its debt issuance, Treasury is dynamically managing financial conditions and, through them, the economy, usurping core functions of the Federal Reserve”, he wrote with economist Nouriel Roubini.

“We dub this novel tool ‘activist Treasury issuance,’ or ATI. By manipulating the amount of interest-rate risk owned by investors, ATI works through the same channels as the Fed’s quantitative easing programs.”

In FT Alphaville last year, Miran co-authored a piece warning against the perils of a two-tier bond market, which “would impair Treasuries’ ability to serve as risk-free collateral underpinning the global financial system” and bring to the US the chaos of a defaulting emerging economy.

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Miran has also hit out at Powell for urging more aggressive fiscal and monetary stimulus in October 2020, about a month before that year’s election, to aid the economic recovery amid the Covid-19 pandemic.

“Powell was wrong politically and economically when he urged Congress to ‘go big’ on fiscal stimulus in October of 2020, on the eve of a Presidential election, suggesting that voters favour Democrats’ $3 trillion proposals over Republicans’ $500 billion”, Miran wrote on X in September. “We know what happened next.”

Miran must be confirmed by the US Senate.

Last month, Trump named Kevin Hassett as chair of the National Economic Council.

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Review by Senate Democrats finds more unreported luxury trips by Clarence Thomas

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Review by Senate Democrats finds more unreported luxury trips by Clarence Thomas

The Supreme Court is pictured on Oct. 7 in Washington, D.C.

Mariam Zuhaib/AP


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Mariam Zuhaib/AP

WASHINGTON — A nearly two-year investigation by Democratic senators of Supreme Court ethics details more luxury travel by Justice Clarence Thomas and urges Congress to establish a way to enforce a new code of conduct.

Any movement on the issue appears unlikely as Republicans prepare to take control of the Senate in January, underscoring the hurdles in imposing restrictions on a separate branch of government even as public confidence in the court has fallen to record lows.

The 93-page report released Saturday by the Democratic majority of the Senate Judiciary Committee found additional travel taken in 2021 by Thomas but not reported on his annual financial disclosure form: a private jet flight to New York’s Adirondacks in July and jet and yacht trip to New York City sponsored by billionaire Harlan Crow in October, one of more than two dozen times detailed in the report that Thomas took luxury travel and gifts from wealthy benefactors.

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The court adopted its first code of ethics in 2023, but it leaves compliance to each of the nine justices.

“The highest court in the land can’t have the lowest ethical standards,” the committee chairman, Illinois Sen. Dick Durbin, said in a statement. He has long called for an enforceable code of ethics.

Republicans protested the subpoenas authorized for Crow and others as part of the investigation. No Republicans signed on to the final report, and no formal report from them was expected.

A spokesman for Crow said he voluntarily agreed to provide information for the investigation, which did not pinpoint any specific instances of undue influence. Crow said in a statement that Thomas and his wife Ginni had been unfairly maligned. “They are good and honorable people and no one should be treated this way,” he said.

Attorney Mark Paoletta, a longtime friend of Thomas who has been tapped for the incoming Trump administration, said the report was aimed at conservatives whose rulings Democrats disagreed with.

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“This entire investigation was never about ‘ethics’ but about trying to undermine the Supreme Court,” Paoletta said in a statement posted on X.

The court did not immediately respond to a request for comment.

Thomas has said he was not required to disclose the trips that he and his wife took with Crow because the big donor is a close friend of the family and disclosure of that type of travel was not previously required. The new ethics code does explicitly require it, and Thomas has since gone back and reported some travel.

The report traces back to Justice Antonin Scalia, saying he “established the practice” of accepting undisclosed gifts and hundreds of trips over his decades on the bench. The late Justice Ruth Bader Ginsberg and retired Justice Stephen Breyer also took subsided trips but disclosed them on their annual forms, it said.

The investigation found that Thomas has accepted gifts and travel from wealthy benefactors worth more than $4.75 million by some estimates since his 1991 confirmation and failed to disclose much of it. “The number, value, and extravagance of the gifts accepted by Justice Thomas have no comparison in modern American history,” according to the report.

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It also detailed a 2008 luxury trip to Alaska taken by Justice Samuel Alito. He has said he was exempted from disclosing the trip under previous ethical rules.

Alito also declined calls to withdraw from cases involving Donald Trump or the Jan. 6, 2021, attack on the Capitol after flags associated with the riot were seen flying at two of Alito’s homes. Alito has said the flags were raised by this wife.

Thomas has ignored calls to step aside from cases involving Trump, too. Ginni Thomas supported Trump’s efforts to overturn the 2020 presidential election that the Republican lost to Democrat Joe Biden.

The report also pointed to scrutiny of Justice Sonia Sotomayor, who, aided by her staff, has advanced sales of her books through college visits over the past decade. Justices have also heard cases involving their book publishers, or involving companies in which justices owned stock.

Biden has been the most prominent Democrat calling for a binding code of conduct. Justice Elena Kaganhas publicly backed adopting an enforcement mechanism, though some ethics experts have said it could be legally tricky.

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Justice Neil Gorsuch recently cited the code when he recused himself from an environmental case. He had been facing calls to step aside because the outcome could stand to benefit a Colorado billionaire whom Gorsuch represented before becoming a judge.

The report also calls for changes in the Judicial Conference, the federal courts’ oversight body led by Chief Justice John Roberts, and further investigation by Congress.

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Sweden criticises China for refusing full access to vessel suspected of Baltic Sea cable sabotage

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Sweden criticises China for refusing full access to vessel suspected of Baltic Sea cable sabotage

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Sweden has sharply criticised China for refusing to allow the Nordic country’s main investigator on board a Chinese vessel suspected of severing two cables in the Baltic Sea.

The Yi Peng 3 sailed away from its mooring in international waters between Denmark and Sweden on Saturday, and appears to be heading for Egypt after Chinese investigators boarded the ship on Thursday.

The Chinese team had allowed representatives from Sweden, Germany, Finland and Denmark on board as observers, but did not permit access for Henrik Söderman, the Swedish public prosecutor, according to authorities in Stockholm.

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“It is something the government inherently takes seriously. It is remarkable that the ship leaves without the prosecutor being given the opportunity to inspect the vessel and question the crew within the framework of a Swedish criminal investigation,” foreign minister Maria Malmer Stenergard said in comments provided to the Financial Times.

The Swedish government had put pressure on Chinese authorities for the bulk carrier to move from international waters into Swedish territory to allow a full investigation over the severing of Swedish-Lithuanian and Finnish-German data cables last month.

People close to the probe said the boarding of the vessel on Thursday had shown there was little doubt it was involved in the incident.

Yi Peng 3 belongs to Ningbo Yipeng Shipping, a company that owns only one other vessel and is based near the eastern Chinese port city of Ningbo. A representative of Ningbo Yipeng told the FT in November that “the government has asked the company to co-operate with the investigation”, but did not answer further questions.

There is a split among countries over the motivation behind the cutting of the cables. Some people close to the investigation said they believed it was bad seamanship that may have led to the Yi Peng 3’s anchor dragging along the seabed in the Baltic Sea.

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However, other governments have said privately that they suspect Russia was behind the damage and may have paid money to the ship’s crew.

The severing of the two cables was the second time in 13 months that a Chinese ship has damaged infrastructure in the Baltic Sea.

The Newnew Polar Bear, a Chinese container ship, damaged a gas pipeline in October 2023 by dragging its anchor along the bottom of the Baltic Sea for a considerable distance during a storm. Officials reacted slowly to that incident, allowing the vessel to leave the region without stopping, something that they were keen to prevent in the case of the Yi Peng 3.

Nordic and Baltic officials are sceptical about the possibility of the same thing occurring twice in quick succession. “The Chinese must be truly dreadful captains if this keeps on happening innocently,” said one Baltic minister.

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