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A common treatment for your knee osteoarthritis may be making it worse, studies say | CNN

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A common treatment for your knee osteoarthritis may be making it worse, studies say | CNN



CNN
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A typical remedy for some arthritis ache would possibly truly be making the situation worse, based on two new research.

“Knee osteoarthritis is among the most persistent, degenerative and progressive situations, with an estimated incidence of 800,000 sufferers annually within the US alone,” mentioned lead writer of one of many research, Dr. Upasana Bharadwaj.

Osteoarthritis is a typical type of arthritis the place the cartilage inside a joint breaks down over time and the bones round it change, getting worse over time, based on the US Facilities for Illness Management and Prevention.

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At the least 10% of the sufferers within the examine used injections to handle the ache, added Bharadwaj, who’s a postdoctoral analysis fellow within the division of radiology on the College of California San Francisco’s Faculty of Medication. Two of these ache administration injectables are corticosteroids, the extra widespread of the 2, and hyaluronic acid.

The research, which have been offered on the annual assembly of the Radiological Society of North America, used both radiograph or MRI photos to trace the development of osteoarthritis within the knees of sufferers. A few of these sufferers didn’t obtain any remedy and others bought corticosteroid or hyaluronic acid injections, based on the research.

Each papers confirmed a statistically vital improve in development of degenerative modifications in knee cartilage over two years in those who had corticosteroid injections in contrast with those that had hyaluronic acid or no injections, based on the examine authors.

Nonetheless, simply because the pictures would possibly look worse doesn’t all the time imply that the individuals are feeling extra ache, mentioned Azad Darbandi, lead writer of the opposite examine.

“You would possibly see that the knee seems unhealthy on a radiograph, however the affected person won’t be having worse signs,” added Darbandi, a researcher and medical scholar on the Chicago Medical Faculty of Rosalind Franklin College of Medication and Science.

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The research spotlight a debate within the osteoarthritis scientific neighborhood concerning the function of modifications within the construction of the joint. Presently, ache is the primarily acknowledged symptom, mentioned Jason Kim, the Arthritis Basis’s vp of osteoarthritis analysis. Kim was not concerned in both examine.

The takeaway from the research is that corticosteroids must be administered with warning for osteoarthritis ache.

Hyaluronic acid injections could also be a promising choice for managing ache however is much less utilized as a result of there may be much less analysis, and most sufferers should pay out of pocket, Darbandi mentioned.

“Maybe hyaluronic acid injections have to be studied for ache administration extra completely,” he mentioned.

Corticosteroids are a quick approach to get ache aid and management irritation however won’t be choice for long-term remedy, Kim mentioned. Repeated injections can put sufferers in danger for different issues, akin to infections as a result of corticosteroids suppress your immune system, he mentioned.

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And a few individuals could not see vital profit from both steroid or hyaluronic acid injections, Kim added.

For a long-term technique, Kim really helpful constructing a trusted workforce of well being care suppliers, together with your main care physician, orthopedic specialist, bodily therapist, nutritionist and rheumatologist.

It might be useful to handle weight and physique mass index, or BMI, to enhance metabolic results and scale back total irritation, Kim mentioned. It’s additionally essential to attempt to train and be bodily energetic, he mentioned, including that strolling has been confirmed to enhance arthritis.

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Israel’s hostage relief laced with dread: ‘it’s only a glimpse of hope’

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Israel’s hostage relief laced with dread: ‘it’s only a glimpse of hope’

It was the moment Israelis had been yearning for. On Sunday afternoon, 471 long days after they were seized by Hamas in the blackest hour of Israel’s history, three young hostages made the painstaking journey from imprisonment in Gaza to freedom in their homeland.

The release of the three women — Romi Gonen, Emily Damari and Doron Steinbrecher — marked the beginning of a multiphase deal that offers a chance to end the brutal war in Gaza, and the hope of freedom for dozens more hostages after more than 15 months of torment for them, their families and the nation.

But Israelis’ joy and relief at the release is laced with anguish at what the coming weeks will reveal. Israeli officials believe at least half of the remaining 94 hostages are dead. And many doubt the fragile truce will last long enough for all to be returned.

One of the Israeli hostages exiting a vehicle to be handed over to the International Committee of the Red Cross (ICRC) during the hostage-prisoner exchange operation in Saraya Square in western Gaza City on Sunday © AFPTV/AFP via Getty Images

“There is this dichotomy between this state of mind where this might be the last day [of life] for their husband or child — and the possibility that that same person might be sleeping in the room next door by next week,” says Udi Goren, whose family is waiting for the return of the body of his cousin Tal Haimi, who was killed on October 7 and then taken to Gaza.

“I don’t think words can describe the immense disparity between these two emotions.”

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For the past 15 months, the fate of the hostages has been seared into Israel’s national consciousness. Their faces from happier times have been plastered and replastered on buildings and billboards from Haifa to Eilat. Details of their lives fill daily news bulletins. Rallies demanding the government act to secure their release have become a weekly fixture.

But as the clock ticked towards the truce this weekend, alongside the hopes that at least some would finally be freed, there were reminders of how volatile the situation remained. Missiles from Yemen set off the eerie howl of air raid sirens across the country. In Tel Aviv, a Palestinian stabbed an Israeli before being shot dead by a passer-by.

Meanwhile, Israeli warplanes continued to pulverise Gaza into Sunday morning, bringing the death toll in the shattered enclave since the deal was announced last week to more than 140, according to Palestinian officials.

Jubilation in Tel Aviv as news coverage shows the release of the three hostages © Shir Torem/Reuters

“There is a glimpse of hope, but it’s not the light at the end of the tunnel,” said Daria Giladi, as she and a friend joined a rally in support of the hostages in downtown Jerusalem on Saturday evening.

“You’re happy people are coming home, you’re happy the war is going to be over, even for a short while. But there’s still such a long way to go. It’s only a third of the hostages who are supposed to come back [in the first six-week phase of the deal]. So it’s not enough.”

Even for relatives of the 33 hostages due to be released in the first phase of the deal — when children, women, the sick and the elderly will be freed — the uncertainty is acute.

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Former hostage Emily Damari is reunited with family on Sunday © IDF

Sharone Lifschitz’s parents, Yocheved and Oded, life-long advocates of coexistence with the Palestinians, were both seized on October 7. Yocheved was freed 17 days later. But the family has no idea of Oded’s fate. When Yocheved returned, she told her family he was dead. But hostages released a few weeks later in a truce in November 2023 said they had seen him alive.

And so for the past 15 months, the family has waited, hoping against hope for Oded’s safe return, while grappling with the enormity of what it would mean for a frail octogenarian shot in the wrist during Hamas’s assault to have survived so long in Hamas captivity.

“We all fight for him with the belief that, until we know otherwise, we want him back. If his fate and his strength held, and he found a way to survive against all odds, we’re so looking forward to seeing him,” says Lifschitz, her voice catching.

“[But] he saw the destruction of everything he fought for. And then he had to be in the hands of the people who caused [that destruction]. And he had to somehow survive when his health is not strong and he is injured. It’s very hard to wish that on anybody — let alone on a father you love so much.”

Yarden Gonen, sister of released Israeli hostage Romi Gonen (pictured), speaks during a demonstration by families of the captives calling for their release, at a kibbutz near the border with Gaza last August © Jack Guez/AFP via Getty Images

For families whose relatives are not due to be freed until the second and third phases of the deal — when the remaining living male hostages, and then the bodies of those who have died, will be returned — the uncertainty is greater.

When the previous seven-day truce and hostage-for-prisoner exchange took place in November 2023, freeing 110 of the 250 hostages originally seized, many in Israel hoped that it would spawn further such deals, and that the remaining hostages could be brought back soon as well.

But what followed was 14 months of false dawns, as Israel and Hamas repeatedly failed to strike a deal, and the number of living hostages steadily dwindled. Claims by far-right ministers in Benjamin Netanyahu’s government to have repeatedly thwarted an agreement have outraged hostages’ relatives. And it has left those with relatives not due to be released until stages two or three fearing their time may never come.

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Among them is Herut Nimrodi, whose then-18-year-old son Tamir was seized in his pyjamas, barefoot and without his glasses, from his military base near the Erez crossing in the early hours of Hamas’s attack.

Nimrodi knows the exact time — 06.49am — of their last message, when Tamir contacted her and said rockets were landing in the base. The family found out he had been seized when one of her daughters saw a video on Instagram. But in the months since they have had no indication of his condition. In November, they marked his 20th birthday without knowing “if he even reached 19”.

“I know that my son’s name is not on the list [for release in the first phase], because he is a soldier, and we’re terrified,” Nimrodi says. “What I fear is not only that we will not get to the next stage. But also that [once the first group have been released] the lobby [for further releases] will become much smaller, because there will be fewer hostages, and they are only men.”

Recognition is also widespread that, even for those who do come back, the return will just be a first step. Lifschitz says her mother is coping “better than most of us” with the return from her imprisonment.

Relatives and friends of people killed and abducted by Hamas gather in Tel Aviv on Sunday © Oded Balilty/AP

But for those who have spent more than 15 months in captivity, the process is likely to be far harder. Hostages previously released have spoken of being kept in cages, or complete darkness, of being drugged and beaten, and in some cases of suffering or witnessing sexual abuse.

Hagai Levine, a physician working with a forum supporting the families of hostages, said in a press briefing last week that he expected “every aspect of [hostages’] physical and mental health will be affected”. “Time is of the essence — recovery will be a long and excruciating process,” he said.

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But for all the angst over the challenges ahead, families are desperate for the process to begin. “Everyone in Israel — and of course the families — needs closure. We are a wounded society right now. We’re in trauma. We didn’t even start the post-trauma yet,” says Nimrodi. “We need to heal. And to see hostages coming back is a healing process for us as a community.”

Lifschitz agrees. “We know that so many hostages are not alive and we will have quite a few funerals and shivas [mourning periods] to sit through,” she says. “But at least, there will be a kind of closure. We will know. At least we will know.”

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Joe Biden's complicated legacy : Consider This from NPR

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Joe Biden's complicated legacy : Consider This from NPR

President Joe Biden delivers his farewell address to the nation from the Oval Office of the White House on January 15, 2025.

Mandel Ngan/Pool/Getty Images


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Mandel Ngan/Pool/Getty Images


President Joe Biden delivers his farewell address to the nation from the Oval Office of the White House on January 15, 2025.

Mandel Ngan/Pool/Getty Images

When he ran for office in 2020, President Joe Biden vowed to turn the page on then president Donald Trump. But it’s Trump who is returning to the White House for a second term in office.

We speak with NPR’s Asma Khalid, who covered the Biden administration, on the legacy he leaves behind.

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For sponsor-free episodes of Consider This, sign up for Consider This+ via Apple Podcasts or at plus.npr.org.

Email us at considerthis@npr.org.

This episode was produced by Jordan Marie Smith and Brianna Scott. It was edited by Roberta Rampton, Adam Raney and Jeanette Woods. Our executive producer is Sami Yenigun.

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Biden to Spend a Last Day as President in Charleston

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Biden to Spend a Last Day as President in Charleston

President Biden will spend his final full day as president in Charleston, S.C., where five years ago he revived his flailing campaign and secured South Carolina’s crucial primary that was widely credited with putting him on the path to the White House.

Mr. Biden will start his day worshiping at the Royal Missionary Baptist Church, a historically Black congregation that he visited on the campaign trail in 2020 before clenching the endorsement of James E. Clyburn, the powerful South Carolina Democratic representative.

During Mr. Biden’s visit, he will observe Martin Luther King Jr. Day, according to a White House official, which will be observed nationally on Monday when Mr. Biden hands the reins of the country over to President-elect Donald J. Trump, who has often shown contempt for contemporary civil rights efforts. Following the service, Mr. Biden will deliver remarks at the International African American Museum.

Mr. Biden’s remarks will focus on Dr. King’s legacy and continued efforts to make his dream of a just society a reality, the White House official said.

It is Mr. Biden’s last official trip as president of the United States, an ode to a state — and its Black electorate — that he has repeatedly credited for enabling him to cap off a half-century career in politics with four years in the White House.

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“The truth is I wouldn’t be here without the people of South Carolina,” Mr. Biden said during a January 2024 visit to the state, speaking to Black voters. “You are the reason that I’m president.”

In an interview with The Post & Courier, the South Carolina publication, the Rev. Isaac Holt, pastor of the Royal Missionary Baptist Church, said that Mr. Biden requested to start a final day in office in the pews of the church. The sermon’s message will focus on Mr. King’s legacy, the pastor said, and his sermon will center on the word “struggle.”

“He’s coming back to where he started,” Mr. Holt told the paper.

It was in Charleston that Mr. Biden, seeking the coveted endorsement of Mr. Clyburn, declared during the Democratic primary debate that he would appoint the first Black, female to the Supreme Court — a standout moment in a crowded field of candidates that garnered a groundswell of support from Black Americans that carried him through the primaries. The White House official called the South Carolina primary a pivotal moment in his campaign to secure the Democratic nomination.

In 2015, when he was vice president, Mr. Biden attended the funeral service of the Rev. Clementa Pinckney, who was murdered along with eight other people in the massacre carried out by a white supremacist at Mother Emanuel A.M.E. Church. Less than a month after the death of one of his sons, Mr. Biden surprised the congregation when he chose to attend and speak at the ceremony at the church, which he said helped him draw strength to endure through his own grief.

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Mr. Biden and his family held hands of congregants and sang “We Shall Overcome.”

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