Nebraska

Nebraska Medicine researchers making strides in Alzheimer’s treament

Published

2 years ago

January 3, 2024

Nebraska Medicine researchers making strides in Alzheimer’s treament

OMAHA, Neb. (WOWT) – Nebraska Medicine and UNMC have been leaders in health and research for decades, and now, the institution is touting its accomplishments when it comes to reducing and reversing the effects and severity of Alzheimer’s.

Inside the walls of the Durham Research Center on UNMC’s campus, research is being done and breakthroughs are being made that could eventually change the lives of millions.

“I think if one has to look at all medical science, medical research, medical investigations, medical therapeutics and pick one that they would like to have a major impact on, it would be neurodegenerative diseases,” said Dr. Howard Gendelman, a UNMC professor of Pharmacology and Internal Medicine.

Dr. Gendelman has dedicated more than two decades to neurodegenerative research, namely, Alzheimer’s.

“So why Alzheimer’s? Alzheimer’s disease is not simply a disease that affects a single person. It affects a family and it affects a community,” Dr. Gendelman said.

The research started with a simple thought: When you scrape your elbow, your immune system responds with redness, swelling, and some pain. After that, your body starts to make repairs to the affected area.

“We reasoned, why can’t we take this simple repair mechanism that is operative on a day-to-day basis in millions of people and look at ways we can harness that to repair the brain in the face of neurodegenerative disease?” said Dr. Gendelman.

So, that’s exactly what the doctor and his team started working towards.

But there were two major obstacles.

The first was simply identifying, isolating, and studying which cells are involved in repairing injuries, like that scraped elbow. After identifying the cells, the next obstacle was figuring out how to get them to respond specifically to the brain.

They found the answer in genetic engineering. Simply put, they’re training the cells to learn a new function, like teaching a dog a new trick.

“We were able to change the repertoire of these immunological cells,” Dr. Gendelman said. “We’re able to get these cells into the area of the brain, have them grow in that area of the brain and ultimately repair the damage that has occurred and improve cognitive function and improve the neurological manifestations of the disease and clear the cause, these plaques that form as Alzheimer’s evolves over time.”

This process is what sets UNMC’s research apart from other Alzheimer’s research and therapies, Gendelman says.

The cellular therapy was then tested, and it did what they hoped and hypothesized that it would do. Dr. Gendelman and his team tested it on mice with the disease and reported that infected mice saw improvements in cognitive function, like learning and memory.

Now, Gendelman says they have the tools, research, and resources to test the therapy in humans, but need to wait for approval from overarching health organizations like NIH and FDA.

It will take time, but they hope to begin human testing in the next two to three years.

“Our biggest reflection of why we do what we do is to say that we’ve made a difference, we’ve made this world better than before we were here before we were involved,” Dr. Gendelman said.

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Nebraska

NioCorp to start work on its minerals mine in southeast Nebraska

Published

5 hours ago

March 2, 2026

Press Room

NioCorp to start work on its minerals mine in southeast Nebraska

NioCorp announced Monday that it plans to start work on its critical minerals mine in southeast Nebraska.

The project, which the company is calling its mine portal project, will involve building a main entrance to the Elk Creek underground mine and will serve as the primary access point for personnel, equipment, and materials for the underground mining operations. It also will include excavating bedrock, drilling and blasting to establish the twin mine ramps, on-site access road construction, and construction of on-site supporting infrastructure.

The project, which will cost nearly $45 million, is set to get underway before the end of the month. It marks the first time Colorado-based NioCorp will actually start any significant work on the main mine, from which the company hopes to extract niobium, scandium, titanium and other minerals.

“Given the size of this excavation work, the portal project really marks the beginning of a major pre-construction activity at the Elk Creek Project site and is an important step toward preparing for underground development,” Scott Honan, the company’s president and chief operating officer, said in a release.

Mark A. Smith, Niocorp’s chairman and CEO, called the project, “a significant milestone.”

Niocorp has spent more than 15 years trying to develop the mine on land in Johnson County, about 65 miles southeast of Lincoln.

The company still needs to raise a significant amount of money to make the $1.2 billion mine a reality, though. In December, NioCorp said it had raised about $360 million, or a little more than a quarter of the total cost. It is still waiting for approval of a $780 million debt financing application from the Export-Import Bank of the United States.

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Nebraska

Nebraska Lottery results: See winning numbers for Pick 3, Pick 5 on March 1, 2026

Published

17 hours ago

March 2, 2026

Press Room

The results are in for the Nebraska Lottery’s draw games on Sunday, March 1, 2026.

Here’s a look at winning numbers for each game on March 1.

Winning Pick 3 numbers from March 1 drawing

7-6-5

Check Pick 3 payouts and previous drawings here.

Winning Pick 5 numbers from March 1 drawing

04-20-28-30-39

Check Pick 5 payouts and previous drawings here.

Winning 2 By 2 numbers from March 1 drawing

Red Balls: 02-10, White Balls: 25-26

Check 2 By 2 payouts and previous drawings here.

Winning MyDay numbers from March 1 drawing

Month: 11, Day: 28, Year: 38

Check MyDay payouts and previous drawings here.

Winning Millionaire for Life numbers from March 1 drawing

10-11-12-35-56, Bonus: 04

Check Millionaire for Life payouts and previous drawings here.

Feeling lucky? Explore the latest lottery news & results

When are the Nebraska Lottery drawings held?

Powerball: 9:59 p.m. CT Monday, Wednesday and Saturday.
Mega Millions: 10 p.m. CT on Tuesday and Friday.
Pick 3, 5: By 10 p.m. CT daily.
Lucky For Life: 9:38 p.m. CT daily.
2 By 2: By 10 p.m. CT daily.
MyDaY: By 10 p.m. CT daily.
Lotto America: 9:15 p.m CT Monday, Wednesday and Saturday.
Millionaire for Life: 10:15 p.m. CT daily.

This results page was generated automatically using information from TinBu and a template written and reviewed by a USA Today editor. You can send feedback using this form.

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Nebraska

Huskers/OSU game three canceled

Published

1 day ago

March 1, 2026

Press Room

Courtesy Nebraska Athletics

The third matchup this weekend between No. 9 Nebraska and No. 21 Oklahoma State was canceled Sunday due to expected bad weather in the Stillwater, Okla., area. The Cowgirls won the first matchup Thursday, 2-1 in 11 innings, while the Cornhuskers won Saturday, 4-3. The game will not be made up.

Nebraska now prepares for its home opener Thursday at Bowlin Stadium as the Huskers take on South Dakota State in a doubleheader. First pitch is scheduled for 4 p.m.

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