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Nebraska Medicine researchers making strides in Alzheimer’s treament

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Nebraska Medicine researchers making strides in Alzheimer’s treament


OMAHA, Neb. (WOWT) – Nebraska Medicine and UNMC have been leaders in health and research for decades, and now, the institution is touting its accomplishments when it comes to reducing and reversing the effects and severity of Alzheimer’s.

Inside the walls of the Durham Research Center on UNMC’s campus, research is being done and breakthroughs are being made that could eventually change the lives of millions.

“I think if one has to look at all medical science, medical research, medical investigations, medical therapeutics and pick one that they would like to have a major impact on, it would be neurodegenerative diseases,” said Dr. Howard Gendelman, a UNMC professor of Pharmacology and Internal Medicine.

Dr. Gendelman has dedicated more than two decades to neurodegenerative research, namely, Alzheimer’s.

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“So why Alzheimer’s? Alzheimer’s disease is not simply a disease that affects a single person. It affects a family and it affects a community,” Dr. Gendelman said.

The research started with a simple thought: When you scrape your elbow, your immune system responds with redness, swelling, and some pain. After that, your body starts to make repairs to the affected area.

“We reasoned, why can’t we take this simple repair mechanism that is operative on a day-to-day basis in millions of people and look at ways we can harness that to repair the brain in the face of neurodegenerative disease?” said Dr. Gendelman.

So, that’s exactly what the doctor and his team started working towards.

But there were two major obstacles.

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The first was simply identifying, isolating, and studying which cells are involved in repairing injuries, like that scraped elbow. After identifying the cells, the next obstacle was figuring out how to get them to respond specifically to the brain.

They found the answer in genetic engineering. Simply put, they’re training the cells to learn a new function, like teaching a dog a new trick.

“We were able to change the repertoire of these immunological cells,” Dr. Gendelman said. “We’re able to get these cells into the area of the brain, have them grow in that area of the brain and ultimately repair the damage that has occurred and improve cognitive function and improve the neurological manifestations of the disease and clear the cause, these plaques that form as Alzheimer’s evolves over time.”

This process is what sets UNMC’s research apart from other Alzheimer’s research and therapies, Gendelman says.

The cellular therapy was then tested, and it did what they hoped and hypothesized that it would do. Dr. Gendelman and his team tested it on mice with the disease and reported that infected mice saw improvements in cognitive function, like learning and memory.

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Now, Gendelman says they have the tools, research, and resources to test the therapy in humans, but need to wait for approval from overarching health organizations like NIH and FDA.

It will take time, but they hope to begin human testing in the next two to three years.

“Our biggest reflection of why we do what we do is to say that we’ve made a difference, we’ve made this world better than before we were here before we were involved,” Dr. Gendelman said.



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What channel is Nebraska softball vs Alabama on today? WCWS game time, TV schedule

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What channel is Nebraska softball vs Alabama on today? WCWS game time, TV schedule


Jordy Frahm and the Nebraska Cornhuskers face Jocelyn Briski and the Alabama Crimson Tide in an NCAA softball Women’s College World Series winners’ bracket game Saturday at Devon Park in Oklahoma City.

The Cornhuskers (51-6) beat Arkansas 5-3 in 10 innings on Thursday, while the Crimson Tide (54-7) beat UCLA 6-3 in its WCWS opener.

Here’s how to watch the Cornhuskers-Crimson Tide game today, including time, TV schedule and streaming information:

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What time is the Alabama vs Nebraska softball Women’s College World Series game on TV?

  • Date: Saturday, May 30
  • Time: 6 p.m. CT

The Alabama Crimson Tide and Nebraska Cornhuskers will play in a 2026 Women’s College World Series winners’ bracket game on Saturday at Devon Park in Oklahoma City.

What channel is the Nebraska softball vs Alabama WCWS game on? Where to watch Cornhuskers-Crimson Tide

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When is the Women’s College World Series? What is the 2026 WCWS schedule?

The 2026 Women’s College World Series gets under way with four games at Devon Park in OKC on Thursday, May 28.

Here’s the full schedule for the 2026 Women’s College World Series at Devon Park in Oklahoma City:

All times Central

Thursday, May 28

Friday, May 29

Saturday, May 30

Sunday, May 31

  • Game 9: Texas vs. Game 8 loser, 2 p.m., ABC (Fubo)
  • Game 10: UCLA vs. Game 7 loser, 6 p.m., ESPN2 (Fubo)

Monday, June 1

  • Game 11: Game 7 winner vs. Game 9 winner, 11 a.m., ESPN (Fubo)
  • Game 12 (if necessary): Game 7 winner vs. Game 9 winner, 1:30 p.m., ESPN (Fubo)
  • Game 13: Game 8 winner vs. Game 10 winner, 6 p.m., ESPN2 (Fubo)
  • Game 14 (if necessary): Game 8 winner vs. Game 10 winner, 8:30 p.m., ESPN2 (Fubo)

Tuesday, June 2

Wednesday, June 3

  • WCWS finals Game 1: TBD vs. TBD, 7 p.m., ESPN (Fubo)

Thursday, June 4

  • WCWS finals Game 2: TBD vs. TBD, 7 p.m., ESPN (Fubo)

Friday, June 5 (if necessary)

  • WCWS finals Game 3: TBD vs. TBD, 7 p.m., ESPN (Fubo)



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What channel is Ole Miss baseball vs Nebraska on today? Time, TV schedule to watch NCAA regional game

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What channel is Ole Miss baseball vs Nebraska on today? Time, TV schedule to watch NCAA regional game


Ole Miss baseball continues on in the winner’s bracket of the NCAA Lincoln Regional with a game against host Nebraska on May 30.

The Rebels (37-21) outlasted Arizona State 7-6 in 14 innings on May 30 after a Brayden Randle walk-off RBI single.

Nebraska (43-15) pulled away late in a 4-1 win over South Dakota State to open regional play on May 30.

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The winner will play in the regional final on May 31, with two games to win one. The loser will play in the first game on May 31 against the South Dakota State-Arizona State winner.

Here’s how you can watch Ole Miss baseball vs. Nebraska:

Ole Miss baseball vs Nebraska on May 30 in Lincoln, Nebraska will be televised on ESPNU. Karl Ravech and Kyle Peterson will call the game in Lincoln.

  • Game date: Saturday, May 30
  • Start time: Approximately 7 p.m.

Friday, May 29

  • Game 1: Nebraska vs. South Dakota State, 3 p.m. on ESPN+
  • Game 2: Ole Miss vs. Arizona State, 8 p.m. on ESPN2

Saturday, May 30

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  • Game 3: South Dakota State vs. Arizona State, 2 p.m. on ESPN+
  • Game 4: Nebraska vs. Ole Miss, approx. 7 p.m. on ESPNU

Sunday, May 31

  • Game 5: Game 3 winner vs. Game 4 loser, 2 p.m. on TBD
  • Game 6: Game 4 winner vs. Game 5 winner, approx. 7 p.m. on TBD

Monday, June 1

  • Game 7: Game 4 winner vs. Game 5 winner (if necessary), Time and TV TBD



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Nebraska Man Fractures Spine After Falling Off Big Boy Locomotive At Whistle-Stop

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Nebraska Man Fractures Spine After Falling Off Big Boy Locomotive At Whistle-Stop


A Kearney, Nebraska, man who loves the giant Big Boy 4014 suffered a small fracture to his spine when he fell off a ladder trying to climb into the cab of the locomotive during its historic whistle-stop tour on Thursday.

Trevor Allen Bentley told Cowboy State Daily that he was about to fulfill a longtime dream of riding inside the cab of the world’s largest operating locomotive. 

He was climbing on the outside of the Cheyenne-based locomotive and had one more step to go on the five-rung ladder to get into the cab when he fell backward about 8 feet, landing hard on the ground.

A 16-second video posted (see below) shows the heavyset man, wearing a bright yellow construction vest, jeans and tennis shoes, gripping the handles on either side of the ladder and struggling to get up to the last step. 

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After a few seconds, he slips and falls to the ground, landing on his back between the train tracks.

Three others nearby, also in bright-colored vests, were at Bentley’s side immediately. Instinct seemed to kick in as they attempt to help him sit up.

Bentley said he was able to sit up and that he wanted to get up right away.

“I felt fine,” he told Cowboy State Daily on Friday. “Obviously, I was sore. But I just wanted to get up.”

He said he was more embarrassed than anything, “because the Big Boy attracts a show.”

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He guessed a few hundred people had turned out to see the Big Boy at the station.

It also was raining, a factor Bentley said likely contributed to his slip.

Onlookers mill about as paramedics respond at the site where a man fell 8 feet from a Big Boy cab Thursday.

Ride Of A Lifetime Dashed

Bentley, who works for the online news site CentralNebraskaToday.com, had planned to ride Big Boy 4014 on its approximate 40-mile leg between Kearney and Grand Island, Nebraska, documenting the trip on video for the outlet. 

He said he had emailed Union Pacific to request the ride, which the railroad granted.

In a social media post he shared after the fall, he wrote, “A boyhood dream got dashed as I fell 8 feet off of Big Boy 4014 before I got the ride of a lifetime.”

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He later told Cowboy State Daily he has been a train enthusiast all his life. He had been in the Big Boy cab before, he said, “which is why I thought I could do it.”

“I just couldn’t get that last step in,” he added. 

30-Minute Delay

Big Boy was already running behind schedule when it pulled into the Kearney station, said Bentley. His fall caused an added 30-minute delay.

North Platte resident James Burns said he frequently visits the tracks and had decided to follow Big Boy from North Platte to Kearney. 

He was at the stop, taking pictures of Big Boy 4014 when Bentley fell, though he told Cowboy State Daily he did not see the fall. He also confirmed the incident caused an approximate 30-minute travel delay.

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The fall sparked a lot of speculation on social media, with comments ranging from prayers that Bentley was OK to sharper criticisms of Bentley’s attempt to climb aboard. One such criticism was his wearing tennis shoes rather than work boots.

Bentley was taken via ambulance to CHI Good Samaritan Hospital in Kearney and said he was released later that day.

A Nebraska man told Cowboy State Daily he suffered a spine fracture in a fall climbing into the cab of the Big Boy 4014 locomotive on Thursday. “A boyhood dream got dashed as I fell 8 feet off of Big Boy 4014 before I got the ride of a lifetime,” he said.
A Nebraska man told Cowboy State Daily he suffered a spine fracture in a fall climbing into the cab of the Big Boy 4014 locomotive on Thursday. “A boyhood dream got dashed as I fell 8 feet off of Big Boy 4014 before I got the ride of a lifetime,” he said.

‘No Fault of UP’

He was home resting when he spoke with Cowboy State Daily via phone Friday.

“I’m just stiff more than anything,” he said, adding that he hopes to be back to work next week. “I am just extremely lucky.”

Bentley wanted to make it clear that his fall was no fault of Union Pacific or anyone but himself. He said what happened was a total accident and that’s why he signed a waiver with UP about riding in the locomotive.

“I do not fault them in any way, shape, or form,” he said. “I don’t want to put a blemish on their tour. It was no fault of Union Pacific. It was on my own accord.”

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Union Pacific publicly responded to the incident in a 16-word statement: “We are glad the person is OK and appreciate the concern we’ve heard from rail fans.”

Contact Kate Meadows at kate@cowboystatedaily.com

Big Boy 4014 at the railroad station in Kearney, Nebraska, on Thursday, May 28, 2026, during a whistle-stop on its corss-country tour.
Big Boy 4014 at the railroad station in Kearney, Nebraska, on Thursday, May 28, 2026, during a whistle-stop on its corss-country tour.

Kate Meadows can be reached at kate@cowboystatedaily.com.



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