The Kansas Metropolis Chiefs open the 2022 NFL season on the street in opposition to the Arizona Cardinals in a Week 1 late afternoon matchup. Kickoff on Sunday, Sept. 11, is 4:25 p.m. ET (FOX) at State Farm Stadium. Beneath, we analyze Tipico Sportsbook‘s strains across the Chiefs vs. Cardinals odds and contours; examine again for our NFL picks and predictions.

The Chiefs have received the AFC West 6 straight seasons and have been to the postseason 7 straight years. They are going to start their quest to proceed that run with QB Patrick Mahomes nonetheless main the best way, though this would be the first season with out WR Tyreek Hill, who was traded to Miami  within the offseason. Mahomes will face his former Texas Tech coach, Kliff Kingsbury, who now leads the Cardinals.

The Cardinals began final season 7-0 and 10-2, however then misplaced 4 of their closing 5 video games within the common season and had been embarrassed within the first spherical of the playoffs. QB Kyler Murray acquired an enormous contract extension and now they hope to return to postseason play, solely with out the late-season collapse.

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Chiefs at Cardinals odds, unfold and contours

Odds supplied by Tipico Sportsbook; entry USA TODAY Sports activities Scores and Sports activities Betting Odds hub for a full record. Traces final up to date Monday, Aug. 29 at 12:35 a.m. ET.

Cash line (ML): Chiefs -190 (wager $190 to win $100) | Cardinals +155 (wager $100 to win $155)
In opposition to the unfold (ATS): Chiefs -3.5 (-110) | Cardinals +3.5 (-110)
Over/Underneath (O/U): 53.5 (O: -108 | U: -112)

2021 betting stats:

ML: Chiefs 14-6 | Cardinals 11-7
ATS: Chiefs 10-10 | Cardinals 10-8
O/U: Chiefs 12-8 | Cardinals 8-10

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Chiefs vs. Cardinals head-to-head

The Cardinals and Chiefs have performed one another 13 occasions relationship again to 1970. The Chiefs lead the all-time collection 9-3-1.

The Chiefs have received 4 of the final 5 matchups, relationship again to 2002. They final performed in 2018, a 26-14 win by the Chiefs.

Mahomes is 1-0 in opposition to the Cardinals in his profession. This shall be Murray’s first profession begin in opposition to the Chiefs.

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