Health
'Pendulum lifestyle' could be key to juggling daily challenges
For those who are feeling “stuck” or overwhelmed while striving for work-life balance, some experts recommend adopting a “pendulum lifestyle.”
Coined by Dr. Jeffrey Karp, Ph.D, a professor of biomedical engineering at Brigham & Women’s Hospital Harvard Medical School in Boston, the pendulum lifestyle is defined as a “concept that acknowledges life’s natural ebb and flow, and empowers you to thrive amidst the swings.”
“Rarely are we in balance … it’s just unrealistic and an anxiety-inducing expectation,” the doctor told Fox News Digital in an interview.
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Seeing the world as a pendulum fosters a more compassionate mindset and alleviates the pressure to be perfect, Karp said.
For those who are feeling “stuck” or overwhelmed while striving for work-life balance, some experts recommend adopting a “pendulum lifestyle.” (iStock)
With this approach, people can take small steps to “swing the pendulum,” enabling them to feel more emotionally, mentally and physically “balanced” during the day, according to the expert.
This could also empower individuals who feel “stuck” when facing daily challenges, he said.
“Looking at nature, there are so many cycles, so many things that are kind of going back and forth, like night and day …. changes of seasons, and the waxing and waning of the moon,” noted Karp.
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The pendulum lifestyle involves daily “self-check-ins” where the person gauges their physical, emotional and mental energy levels, Karp said. They can then take immediate steps to move their levels in a positive direction toward the ideal balance.
“If we can visualize everything on a pendulum, we can think, ‘What’s the one step I could take today to bring the pendulum a little closer to where I want it to be?’” he said.
With this approach, people can take small steps to “swing the pendulum,” enabling them to feel more emotionally, mentally and physically “balanced” during the day. (iStock)
For example, a person who has low physical energy could visualize a pendulum with the lowest energy on one side and the highest energy on the other.
He would then do a “self-check” to identify where his energy level lies on the pendulum and what small steps could move it closer to the ideal balance point, Karp said.
“True well-being doesn’t lie in perfection or consistency, but in our ability to navigate the ebb and flow of life.”
That might mean taking a 10-minute walk, doing some jumping jacks or performing a few stretches to move the pendulum to a higher energy level position.
“This empowers the person and reminds them they are not stuck,” Karp said.
Taking a 10-minute walk, doing some jumping jacks or performing a few stretches can move the pendulum to a higher energy level position, the expert said. (iStock)
On the flip side, if it’s late at night and a person needs to wind down, she might engage in a calming exercise like meditation or listening to relaxing music as a way to swing the pendulum to a level more conducive to sleeping, the expert advised.
The pendulum lifestyle can also serve as a mood-booster, Kelp said. When someone is feeling down, watching a funny movie or practicing gratitude can help shift the pendulum.
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The approach could also help launch forward momentum if someone feels “stuck” in life, the expert said.
“When you start to realize that you’re not limited to being at that spot on the pendulum, but can take a step forward and be intentional, it’s just so empowering,” he said.
The daily check-in process could help individuals identify when they are feeling in less than tip-top shape and find ways to swing in a better direction, one expert said. (iStock)
Dr. Molly Sherb, an assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai and a licensed psychologist at Mount Sinai in New York City, commented on Karp’s concept of a pendulum lifestyle.
“When you start to realize that you’re not limited to being at that spot on the pendulum, but can take a step forward and be intentional, it’s just so empowering.”
She agreed that the daily check-in process could help individuals identify when they are feeling in less than tip-top shape and find ways to swing in a better direction.
“That might include getting better sleep or eating a healthier breakfast … to help you wake up with a better bandwidth tomorrow,” Sherb said.
Progress, not perfection
Dr. Christopher Fisher, a psychologist at Zucker Hillside Hospital Northwell Health in Queens, New York, said the pendulum lifestyle could help those who feel pressured to achieve a perfect work-life balance.
“The pendulum of life’s experiences – whether emotional, cognitive or physical – is one of the truest expressions of what it means to be human,” he told Fox News Digital.
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“True well-being doesn’t lie in perfection or consistency, but in our ability to navigate the ebb and flow of life,” he told Fox News Digital.
Sherb agreed that the essence of the pendulum lifestyle is that it’s not always possible to strike that 50-50 equal balance.
Adopt a constructive viewpoint and ask yourself what positive changes or routines can help you achieve a more optimal level on the pendulum path, one expert advised. (iStock)
“It’s about constantly tuning into yourself … and seeing which parts of your life might need you more at certain times,” she said.
“It’s not a one-size-fits-all approach, but a more tailored approach based on what you need and what people in your life need from you.”
4 steps to implementing the pendulum lifestyle
Karp shared some specific strategies for adopting the pendulum approach.
1. Perform a head-to-toe check-in each morning
Ask yourself how you are feeling emotionally, physically and mentally. What parts do not feel at a 100% level?
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2. Make any necessary adjustments
Based on your self-check-in, consider changing your routine to accommodate your energy level or take simple steps to help move the pendulum in a positive direction, Karp suggested.
3. Be compassionate and curious
If you feel off-balance, Karp said to recognize that as part of the natural pendulum swing and to embrace it with self-compassion rather than shame and criticism.
“It’s about constantly tuning into yourself … and seeing which parts of your life might need you more at certain times.”
Adopt a constructive viewpoint and ask yourself what positive changes or routines can help you achieve a more optimal level on the pendulum path, he advised.
4. Understand your pendulum swings
It could be helpful to ask yourself specific questions, such as the following.
“What factors helped contribute to a state of feeling balanced?”
“What factors contributed to feeling off-balance?”
“What small changes can I make today to foster a sense of better balance?”
“How did I respond to feeling imbalanced and was it effective?”
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Above all, Karp said, it’s important to remember that finding balance is a “lifelong journey.”
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A new injectable therapy is showing positive results in reducing melanoma throughout a five-year period.
The personalized mRNA cancer therapy, called intismeran autogene, combined with the cancer immunotherapy drug KEYTRUDA (pembrolizumab), is a collaboration between Merck and Moderna.
The results from the phase 2b KEYNOTE-942 study were presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on May 27.
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After about a five-year follow-up, the combo drug was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone.
The researchers analyzed data from 157 patients with high-risk stage 3 and 4 melanoma whose cancer had been removed via surgery. The participants were split into two groups — one received the combo therapy and the other only received pembrolizumab, according to a press release.
The therapy was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone after a five-year follow-up. (iStock)
The findings revealed that the combination group saw benefits that were “sustained and durable over time.”
Intismeran autogene is designed using mutations identified in a patient’s own tumor, with the intention of teaching the immune system what the cancer looks like so that it can recognize and attack it.
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According to the researchers, intismeran is “well-tolerated” with a “manageable” safety profile.
The most commonly cited side effects of the personalized mRNA vaccine plus KEYTRUDA were fatigue, injection-site pain, chills, fever and headache. The researchers reported no new long-term safety concerns and no severe vaccine-related adverse events.
The combination therapy is currently being evaluated in a phase 3 study — the final confirmation stage.
Patients with late-stage melanoma have a “significant risk” of cancer recurrence, according to an expert. (iStock)
In a Merck press release from January, Kyle Holen, MD, Moderna’s senior vice president and head of development, oncology and therapeutics, noted that this data highlights the “potential of a prolonged benefit … in patients with resected high-risk melanoma.”
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“We continue to invest in our platform in oncology because of encouraging outcomes like these, which illustrate mRNA’s potential in cancer care,” he said.
Dr. Marjorie Green, senior vice president and head of oncology, global clinical development at Merck Research Laboratories, also commented that for many patients with stage 3 or 4 melanoma, there is a “significant risk of recurrence following surgery.”
Researchers confirmed that the combination therapy is currently being evaluated in a phase 3 study. (iStock)
“As such, demonstrating the longer-term potential of intismeran autogene and KEYTRUDA to reduce the risk of recurrence for certain patients with melanoma is a meaningful milestone,” she said.
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The company cited encouraging five-year follow-up data and pointed to upcoming late-stage INTerpath trial results with Moderna in several hard-to-treat cancers.
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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.
By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.
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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.
“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)
While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.
Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.
“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”
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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.
The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.
Clinical treatments remain identical for both primary strains of the flu virus. (iStock)
During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.
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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.
Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.
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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.
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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”
This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)
“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”
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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.
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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.
Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.
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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.
While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.
To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years.
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The study group included 131,426 men and 318,686 women, according to the study’s press release.
During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.
For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)
Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.
The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.
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After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.
A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.
An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)
An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.
The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.
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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.
The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.
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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.
Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)
Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.
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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.
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The findings were published in the International Journal of Cancer.
Fox News Digital reached out to the researchers requesting comment.
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