Health
Ozempic and similar drugs could interfere with common medical procedure, research warns
GLP-1 weight loss pill in development
Fox News senior medical analyst Dr. Marc Siegel discusses advancements in weight loss drugs, safety concerns surrounding nicotine patches and his interview with FDA Commissioner Dr. Marty Makary on vaccine protocol.
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Researchers have revealed a surprising new side effect linked to GLP-1 agonists, such as Ozempic, Wegovy, Mounjaro and Zepbound.
These popular treatments for diabetes and obesity could interfere with medical imaging, such as PET and CT (“CAT”) scans.
CT scans are often used to get detailed internal images to detect injuries, tumors or other abnormalities, according to Cleveland Clinic. A typical use of PET scans is to examine organs and tissues, detect cancer activity or monitor how the body is responding to treatment.
DANGEROUS ‘GRAY-MARKET’ WEIGHT-LOSS DRUGS FLOODING US AS EXPERTS WARN OF RISKS
In the case review, presented this week at the 38th Annual Congress of the European Association of Nuclear Medicine in Barcelona, Spain, researchers analyzed cancer scans of patients who were taking GLP-1 medications, according to a press release.
They found some “atypical” scan results that could be mistaken as signs of disease.
Popular treatments for diabetes and obesity could interfere with medical imaging, such as PET and CT scans, a study suggested. (iStock)
“We noticed an unusual uptake in one of our patients on a GLP-1 agonist, which prompted a wider review across our network,” lead author Dr. Peter Strouhal, medical director at Alliance Medical Ltd in the U.K., stated in the release.
“We found that these altered patterns are increasingly common, yet there is currently no national or international guidance in the U.K. addressing this emerging issue.”
“It’s something we’ll keep an eye on in our industry, but more information is needed.”
Misunderstanding these scan results can lead to extra tests, incorrect cancer assessments and delays in treatment, which can cause stress and anxiety for patients, the release noted.
“Knowing how GLP-1 medications can affect scan images helps doctors avoid confusion and unnecessary procedures, so patients get the right care quickly and confidently,” Strouhal said.
“We noticed an unusual uptake in one of our patients on a GLP-1 agonist, which prompted a wider review across our network,” the lead study author said. (iStock)
Despite these findings, the researchers said they don’t recommend that patients stop taking GLP-1s prior to having a scan — but they did emphasize that imaging teams should consider patients’ medication use when interpreting scan results.
Looking ahead, the research team plans to gather more data from global imaging centers to strengthen these findings.
Sue Decotiis, M.D., a medical weight-loss doctor in New York City, pointed out that the results of the study are still very preliminary.
“They just noticed an increase, but it didn’t mention which organs or specific body parts,” Decotiis, who was not involved in the study, told Fox News Digital.
Researchers said they don’t recommend that patients stop taking GLP-1s prior to having a scan — but they did emphasize that imaging teams should consider patients’ medication use when interpreting scan results. (iStock)
“It will be important to see more data from many more patients to understand exactly what they saw. It’s something we’ll keep an eye on in our industry, but more information is needed.”
Adam Wolfberg, M.D., chief medical officer at Virta Health in Massachusetts, also reflected on the study.
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“GLP-1s have many effects on the body, and one of them is altering the way glucose is metabolized,” Wolfberg, who also did not take part in the study, told Fox News Digital. “Since the tracer agent used in these PET scans contains glucose, uptake of the agent — a metabolic ‘dye’ of sorts — can be impacted.”
“Interpretation of the corresponding images would require knowledge of this clinical background.”
“Knowing how GLP-1 medications can affect scan images helps doctors avoid confusion and unnecessary procedures, so patients get the right care quickly and confidently,” the researcher said. (iStock)
He echoed, however, that he doesn’t think this finding is a “big deal.”
“PET scans are always interpreted in the context of the whole patient,” Wolfberg said. “A skilled oncologist or radiologist would always take into account a patient’s medical history as well as the medications they are taking when reading this type of scan.”
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Wolfberg agreed that much more data would be required before these observations should impact medical practice.
Fox News Digital reached out to the researchers for comment, as well as to manufacturers of GLP-1 medications.
Health
Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns
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Americans consume foods every day that are marketed as “healthy,” when they could be quietly destroying their health, one doctor warns.
Dr. Mark Hyman, physician and co-founder of Function Health in California, says that much of America’s daily diet is filled with unhealthy ingredients.
“The amount of refined starches and sugars that are everywhere is just staggering to me, given what we know about how harmful they are,” he shared in an interview with Fox News Digital. “I don’t think people really understand.”
Hyman, author of the new book “Food Fix Uncensored,” said he’s “astounded” by what people are eating, especially for breakfast.
“People just eat sugar for breakfast,” he said. “They have muffins, they have bagels, they have croissants, they have sugar-sweetened coffees and teas.”
Dr. Mark Hyman is the author of the new book “Food Fix Uncensored.” (Function Health; Little, Brown Spark)
In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products, following health trends that encourage eating more protein.
“Highly processed food is not food.”
“Now, we’re seeing this halo of protein in certain things,” Hyman said, mentioning that many protein smoothies are “full of sugar.”
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The doctor also noted that some popular cereals are now marketed as having protein in them. “My joke is, if it has a health claim on the label, it’s definitely bad for you,” he said.
Instead of starting the day with a “quick fix” or processed food, Hyman suggests choosing whole sources of protein and fat for breakfast, adding that “if there’s a little carbohydrate in there, it’s fine.”
More products marketed as “high protein” have cropped up on supermarket shelves. (iStock)
For his own breakfast, Hyman said he has a protein shake with whey protein, avocado and frozen berries. Eggs and avocados are also a great protein-and-fat combo option, he added.
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“It’s not that complicated — people need to just think about their breakfast not being dessert,” he said. “No wonder we’re in this cycle of obesity and diabetes. One in three teenage kids now has type 2 diabetes or pre-diabetes. That’s just criminal.”
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Instead of counting calories and being in a caloric deficit as a way to lose weight and stay healthy, Hyman instead suggests focusing on how certain foods make you feel and how they impact your health.
“When you look at the way in which different types of calories affect your biology, you can just choose what you’re eating, and then you don’t have to worry about how much,” he told Fox News Digital.
In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products. (iStock)
“For example, if you eat a diet that doesn’t cause your insulin to spike — which is low in starch and sugar, higher in protein and fat — you won’t develop those swings in blood sugar, you won’t develop the spikes in insulin, you won’t deposit hungry fat … You will break that cycle.”
People are more likely to “self-regulate when they eat real food” instead of processed foods, which “bypasses the normal mechanisms of satiety, fullness and brain chemistry,” according to Hyman.
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“Ultraprocessed food and junk food or highly processed food is not food,” he said. “It doesn’t support the health and well-being of an organism. It doesn’t do that. It does the opposite.”
Health
Scientists make startling discovery when examining prostate cancer tissue
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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health.
In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.
The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.
In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)
The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.
Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.
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The scientists say this is the first direct evidence linking microplastics to prostate cancer.
“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)
The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.
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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.
“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”
“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.
Study limitations
Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.
“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.
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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”
About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.
The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)
For those concerned about microplastics, Sidransky offered some insights.
“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.
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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”
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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.
Health
How a Vegan Diet Can Help You Lose Weight 8X Faster
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