Health
Aggressive cancer warning signs revealed after JFK’s granddaughter’s diagnosis
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Days after Tatiana Schlossberg announced that she has terminal cancer, the spotlight is on the warning signs of acute myeloid leukemia (AML).
John F. Kennedy’s granddaughter, 35, shared the details of her diagnosis in an essay published in The New Yorker on Nov. 22.
Schlossberg, who is the daughter of Kennedy’s daughter, Caroline Kennedy, and Edwin Schlossberg, learned of her disease in May 2024.
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She wrote that one doctor predicted she would live for about a year.
The first indicator of Schlossberg’s disease was an abnormally high white blood cell count, which doctors detected just hours after she gave birth to her second child.
John F. Kennedy’s granddaughter, 35, shared the details of her diagnosis in an essay published in The New Yorker on Nov. 22. She’s pictured here in 2023. (AP Newsroom)
What is acute myeloid leukemia?
AML is a type of leukemia that begins in the bone marrow, the soft, inner tissue of certain bones where new blood cells are produced, according to the American Cancer Society.
This type of cancer typically spreads rapidly from the bone marrow into the bloodstream and can also reach other parts of the body, such as the lymph nodes, liver, spleen, brain and spinal cord, and testicles, per ACS.
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In some cases, clusters of leukemia cells may form a solid mass known as a myeloid sarcoma.
Schlossberg’s AML stems from a rare gene mutation known as inversion 3, which is an abnormality of chromosome 3 in the leukemia cells.
Schlossberg, the daughter of Caroline Kennedy (left) and Edwin Schlossberg, learned of her disease in May 2024. (Getty Images)
“Inversion 3 correlates with a very high rate of resistance to standard chemotherapy treatments and, therefore, very poor clinical outcomes,” Dr. Stephen Chung, a leukemia expert and oncologist at UT Southwestern Medical Center in Dallas, Texas, told Fox News Digital. (Chung was not involved in Schlossberg’s care.)
Red flags and risk factors
The most common symptoms of Schlossberg’s type of cancer include sudden onset of severe fatigue, shortness of breath with exertion, unusual bleeding or bruising, fever and infections, according to Dr. Pamela Becker, professor in the Division of Leukemia at City of Hope, a U.S. cancer research and treatment organization in California, who also did not treat Schlossberg.
AML can sometimes resemble a severe flu with a generally unwell feeling.
Chung noted that AML usually causes abnormally low blood cell counts, or in some cases an abnormally high white blood cell count.
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“This may be picked up in routine testing for other purposes, or because the patient develops symptoms from these low blood counts,” he said.
AML can sometimes resemble a severe flu with a generally unwell feeling, noted Robert Sikorski, M.D., Ph.D., a hematology/oncology expert and chief medical officer of Cero Therapeutics in California.
“Some patients also experience bone pain or night sweats,” he told Fox News Digital.
Standing outside the John F. Kennedy Library in Boston, from left, Edwin Schlossberg, Rose Schlossberg, Victoria Reggie Kennedy, Ted Kennedy, Tatiana Schlossberg and Caroline Kennedy Schlossberg. Tatiana Schlossberg said a doctor gave her an estimated one year to live. (Getty Images)
Known risk factors for AML include prior chemotherapy or radiation, smoking, long-term benzene exposure and certain inherited syndromes, although most cases occur without any identifiable cause, according to Sikorski, who has not treated Schlossberg.
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In some rare cases, people can inherit mutations that cause AML to run in families, with recent research suggesting that these cases may be more common than previously thought, Chung noted.
“We used to only check for this in younger AML patients, but we now believe all patients should be screened for these mutations,” he said.
Treatment for AML
The standard treatment for AML is intensive chemotherapy with a combination of two drugs, with additional agents added based on each patient’s specific characteristics, according to Becker.
“We now believe all patients should be screened for these mutations.”
For patients with higher-risk types of AML, the chemotherapy is usually followed by a stem cell (bone marrow) transplant to prevent relapse. The transplants come from matched donors, often family members.
“This is a much more involved process that usually involves another month in the hospital, followed by close follow-up for many months, as well as a much higher risk for treatment-related side effects,” Chung said.
There is not a specific treatment that is effective for Schlossberg’s specific chromosome abnormality, the doctors noted, although some new cellular therapies and immunotherapies are being investigated.
Caroline Kennedy’s children, Jack and Tatiana Schlossberg, and her husband Edwin Schlossberg are pictured on Capitol Hill in 2013. The first indicator of Schlossberg’s disease was an abnormally high white blood cell count, which doctors detected just hours after she gave birth to her second child in 2024. (Getty Images)
For older patients who are not strong enough to receive intensive chemotherapy, the standard treatment is venetoclax/azacytidine (a combination therapy used to treat certain types of AML), Chung said.
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“This can often be given mostly outside the hospital on a monthly basis,” he said. “While it technically is not considered to be curative, it can work very well — in some cases, patients remain in remission for many months, if not years.”
Hope ahead
There is hope on the horizon, as AML treatment has advanced more in the past decade than in the previous 30 years, according to Sikorski.
Caroline Kennedy is pictured with her children Rose Schlossberg (left), Tatiana Schlossberg (center) and Jack Schlossberg at the 2008 Democratic Convention in Denver, Colorado. There is hope on the horizon for AML treatment, doctors say. (Getty Images)
“New targeted drugs have been approved in several AML subtypes, and early work in immune-based therapies, including CAR-T and other engineered cell therapies, is beginning to reach clinical trials for AML,” Sikorski, told Fox News Digital.
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“Supportive care has also improved significantly, which helps patients tolerate treatment more effectively.”
While there is not yet a drug tailored specifically to inversion 3, he reiterated, “many studies focused on high-risk AML are actively enrolling these patients, and the overall treatment landscape continues to expand.”
Health
The everyday places Americans could be exposed to hantavirus — without knowing it
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Amid the current hantavirus outbreak that started on the MV Hondius cruise ship as it sailed across the Atlantic, health experts are now examining whether Americans may be encountering the virus in everyday places without realizing it.
The rare Andes strain, which was linked to the MV Hondius outbreak, is the only known hantavirus that has the capability to spread from person to person, usually through prolonged close contact with an infected person.
Most cases of hantavirus in the U.S. occur in the desert Southwest and on the West Coast, according to Dr. Linda Yancey, an infectious disease specialist at Memorial Hermann in the Houston area.
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“In Texas, cases are mostly seen on the west side of the state,” she told Fox News Digital. “The strain of hantavirus native to east Texas and west Louisiana, the Bayou strain, is not as infectious in humans as the western strain, the Sin Nombre strain.”
Hantavirus is primarily spread through contact with infected rodents – primarily deer mice – and their urine, droppings or saliva. (iStock)
Hantavirus is mainly spread through contact with infected rodents – primarily deer mice – and their urine, droppings or saliva, according to the Centers for Disease Control and Prevention.
People can become infected after breathing in contaminated particles that are stirred into the air or touching contaminated surfaces and then touching their nose or mouth. More rarely, rodent bites can spread the virus.
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Exposure is most likely when cleaning enclosed or poorly ventilated areas where rodents may nest unnoticed for weeks or months, health officials say.
Risky locations can include garages, sheds, cabins, attics, barns and crawl spaces. Storage units, stables, kitchen cabinets and spaces behind appliances if rodents are present.
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Rodents can also nest in unused cars, RVs, campers and boats, which can be sources of exposure when reopened.
The National Park Service says that most human cases of hantavirus occur in the spring and are linked to buildings that become heavily infested with rodents over the winter.
The risk of inhalation is also higher when opening buildings that have gone unused for longer periods of time, sweeping dusty floors, or moving and unpacking boxes. (iStock)
“Most people are exposed when cleaning out sheds and garages where rodents have been living,” Yancey confirmed. “You can be exposed by just the dust and droppings left behind by rodents – you don’t even need to even see the rodent to be exposed.”
The risk of inhalation is also higher when opening buildings that have gone unused for longer periods of time, sweeping dusty floors or moving and unpacking boxes, experts cautioned.
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Rodent exposure is not limited to buildings. Health officials say people can also encounter hantavirus risk while handling firewood, working in rodent-prone outdoor areas or disturbing rodent nests and burrows.
To prevent infection, if cleaning a structure that might have harbored rodents, Yancey recommends wearing a mask and using a diluted bleach solution to wet down any dust or loose debris.
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“This will help kill the exposed virus and reduce the amount of infectious dust,” Yancey said.
The CDC advises against vacuuming or sweeping rodent urine, droppings or nesting materials, as this can aerosolize the virus and increase the risk of inhalation.
A Spanish passenger boards a government plane after disembarking from the hantavirus-stricken cruise ship MV Hondius at the airport in Tenerife, Canary Islands, on May 10, 2026. (Arturo Rodriguez/AP Photo)
Instead, health officials recommend wearing gloves, soaking rodent droppings with disinfectant, wiping them up with paper towels, properly disposing of waste and thoroughly cleaning surfaces, followed by careful handwashing.
Some signs of rodent activity can include droppings, shredded nesting materials, gnaw marks, strong musky odors and scratching sounds in the walls or ceilings, according to public health guidance.
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Dr. Marc Siegel, Fox News senior medical analyst, emphasized that hantavirus is not something that most Americans encounter in daily life, and is more prominent in certain parts of Europe and Asia.
“It is very rare in the U.S. and is seen out west, but rarely,” he told Fox News Digital. “We need to avoid overpersonalizing the risk of a very rare virus.”
Health
Why So Many Guys Are Obsessed With Testosterone
Despite the anecdotal nature of the study, it had a seismic impact on medical practice. Most doctors stopped prescribing testosterone, cautioning that the risk of prostate cancer was too high. That prohibition lasted for the remainder of the 20th century. For roughly 60 years, “there was almost no testosterone given anywhere in this world,” says Dr. Abe Morgentaler, a urologist at Harvard Medical School. When he was a medical student in the 1980s, Morgentaler told me, “I was taught that if a healthy man received testosterone today, he would come back in one month with aggressive prostate cancer.”
Morgentaler, however, was curious about the hormone’s potential. As an undergraduate conducting research, he found that when castrated lizards were given testosterone, their mating dances were restored. Once he was practicing as a urologist, men started coming to him complaining of sexual problems. It was a decade before the arrival of Viagra, and doctors had little to offer. “I thought, Maybe guys are like my lizards,” Morgentaler says. He started prescribing testosterone to a small group of patients, warning them that it could increase their risk of prostate cancer. Desperate, most men went ahead anyway.
To his surprise, many of his patients reported that not only were they now having lots of sex but also that other aspects of their lives had improved. “They’d say, ‘My wife likes me again,’” he recalls. “Another says, ‘I wake up in the morning, I swing my legs over the side of the bed, I have optimism for my day. I haven’t felt that way in 15 years.’” Over the next decade, as Morgentaler spoke about his patients’ positive outcomes at conferences, including preliminary data suggesting no increase in the incidence of prostate cancer, more doctors began following his lead.
But soon after Morgentaler began treating his patients, a new obstacle arose. Doping scandals swept the world of sports, where athletes trying to set records and win Olympic medals were caught taking testosterone and other anabolic steroids at doses much higher than what Morgentaler was giving his patients. In 1990, Congress passed a law adding steroids, including testosterone, to the Drug Enforcement Administration’s list of controlled substances — making the hormone illegal without a prescription and adding new restrictions for doctors.
Then, after a few studies published in the early 2010s suggested that T.R.T. was associated with a potential increase in heart attacks and strokes, the F.D.A. issued a warning label for testosterone products. As part of the warning, the agency required drug makers to fund what would become the largest randomized, placebo-controlled trial to investigate the risks and benefits of T.R.T.
Health
Cruise passenger shows life inside Nebraska quarantine after hantavirus exposure scare
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One of the passengers aboard the MV Hondius cruise ship posted video showing his quarantine room at the National Quarantine Unit at the University of Nebraska Medical Center in Omaha as officials monitor a hantavirus outbreak tied to the voyage.
Jake Rosmarin, a passenger currently under quarantine, has been documenting his experience on social media, posting videos from both the ship and the medical facility. Fox News Digital has not independently verified the video.
Health officials have said the passengers are being monitored out of caution after potential exposure to Andes virus, a type of hantavirus, and have emphasized that the risk to the public remains low.
In one recent clip, Rosmarin showed his room, which included a wall-mounted hand sanitizer, a thermometer and other health provisions. The room also featured a stationary bike.
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American passengers from the MV Hondius arrive in Omaha, Nebraska, after flying from Tenerife, Spain. (Nick Ingram/AP)
“I can have stuff sent here for the duration of my stay, so I’m definitely going to be getting some things for me to feel more at home and more comfortable,” Rosmarin said.
He added that he plans to continue sharing updates in the coming days and said he is currently feeling “well.”
Rosmarin also said he has not tested positive for hantavirus.
The footage shows conditions inside the quarantine unit as health officials monitor passengers for potential exposure following the outbreak.
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Medical staff direct some of the last passengers to be evacuated from the MV Hondius on May 11, 2026 in Tenerife, part of the Canary Islands, Spain. (Chris McGrath/Getty Images)
Health officials have said passengers may be allowed to leave the Nebraska facility before a 42-day monitoring period ends if they meet certain conditions, including remaining symptom-free and being able to safely isolate at home.
Officials will also evaluate whether individuals can maintain contact with local health departments and quickly access testing or medical care if symptoms develop.
Of the 18 individuals transported to the U.S. after the outbreak, 16 are in Nebraska and two are in Atlanta. Most are in quarantine, while one individual was placed in a biocontainment unit after an earlier test result.
Passengers watch as others disembark from the hantavirus-stricken cruise ship MV Hondius at the port of Granadilla in Tenerife, Canary Islands, Spain, on May 10, 2026. (AP Photo)
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Officials have emphasized that the risk to the general public remains low, noting that the Andes variant of hantavirus does not spread easily and typically requires prolonged, close contact with a symptomatic individual.
Fox News Digital’s Alex Nitzberg contributed to this report.
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