Health
New study hints at a hidden Alzheimer’s risk factor affecting older Americans
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People with greater exposure to air pollution could face a higher risk of developing Alzheimer’s disease, according to a new study by Emory University in Atlanta.
Air pollution has previously been established as a risk factor for Alzheimer’s, as well as other chronic conditions, like hypertension, stroke and depression, the researchers noted.
Since those other conditions are themselves linked to Alzheimer’s, the researchers said it’s not yet clear whether air pollution harms brain health on its own, or whether it raises dementia risk by first triggering those other health problems.
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The study, which was published in the journal PLOS Medicine, investigated more than 27.8 million U.S. Medicare recipients, 65 years and older, from 2000 to 2018.
The individuals were examined for level of exposure to air pollution and whether they developed Alzheimer’s, with a focus on other chronic conditions.
Air pollution may have a direct correlation to Alzheimer’s diagnoses, a new study found. (iStock)
Greater exposure to air pollution was associated with an increased risk of Alzheimer’s, which was slightly stronger in people who had experienced a stroke. Hypertension and depression had “little additional impact,” according to the study’s press release.
The authors concluded that air pollution leads to Alzheimer’s mostly through “direct pathways” rather than via other chronic conditions.
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“Our findings suggest that individuals with a history of stroke may be particularly vulnerable to the harmful effects of air pollution on brain health, highlighting an important intersection between environmental and vascular risk factors,” the authors wrote in a statement.
These findings suggest that improving air quality could be “an important way to prevent dementia and protect older adults,” the press release concluded.
Air quality could be “an important way to prevent dementia and protect older adults,” the researchers suggested. (iStock)
Fox News senior medical analyst Dr. Marc Siegel confirmed more studies are revealing that Alzheimer’s is linked to conditions that impact the brain, which can be “sensitive and fragile.”
“Certainly, underlying medical conditions like stroke can lead to this,” Siegel, who was not involved in the study, told Fox News Digital.
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This latest study “does not show cause and effect,” the doctor noted, but rather shows an “increasing association between air pollution and Alzheimer’s, where the particulate matter appears to increase the inflammation in the brain that helps lead to it.”
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“This is another piece in developing a strategy of prevention, early diagnosis and targeted treatments,” Siegel added.
People with a history of stroke could be more susceptible to air pollution risks, according to the researchers. (iStock)
Ozama Ismail, PhD, director of scientific programs at the Alzheimer’s Association in Chicago, agreed that this study adds to existing research on the impact of air pollution and overall health, especially related to the brain.
“Alzheimer’s is a complex disease, and it is likely that there are a variety of factors … that impact a person’s lifetime risk.”
“This is an area of investigation where more research is vital to helping us better understand the connection between pollution and the various factors that cause or contribute to Alzheimer’s disease,” Ismail, who also did not work on the study, told Fox News Digital.
“Previous studies, including those presented at the Alzheimer’s Association International Conference in 2019, 2021 and 2025, have shown evidence for connections between exposure to air pollution and other environmental toxins and risk for Alzheimer’s or other dementias.”
“Avoiding exposure to air pollution is a risk factor that may be easier for some people to change than others,” one expert said. (iStock)
The Lancet Commission on Dementia Prevention added exposure to air pollution to its list of known dementia risk factors in 2020, according to Ismail.
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“We know that Alzheimer’s is a complex disease, and it is likely that there are a variety of factors, in combination, that impact a person’s lifetime risk,” he said. “Avoiding exposure to air pollution is a risk factor that may be easier for some people to change than others.”
Fox News Digital reached out to the study authors for comment.
Health
‘Call a Boomer’ payphones help cure loneliness, spark friendships across generations
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Along a bustling sidewalk in Boston, a bright yellow payphone invites folks to “call a Boomer.”
Almost 3,000 miles away in Reno, Nevada, a nearly identical phone prompts residents of Sierra Manor – an apartment complex for seniors – to “Call a Zoomer.” The goal is simple: to get strangers to talk to each other.
The project, often referred to as simply “Call a Boomer,” is the latest initiative from Matter Neuroscience, a New York-based company dedicated to mapping the “biomarkers of happiness.”
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By connecting “two of the loneliest demographics” (older adults and younger adults), the project aims to prove that on a molecular level, “humans need one another in order to be happy,” according to Calla Kessler, a social strategist at Matter Neuroscience.
Along a bustling sidewalk in Boston, a bright yellow payphone invites folks to “Call a Boomer.” (Matter Neuroscience)
“Younger adults and older adults tend to experience the highest levels of loneliness of any age group,” the company wrote on its website. “So the goal of this project is to inspire generational connection through meaningful conversations, despite differences in age, lifestyle or politics.”
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The hope, according to Kessler, is that the calls will shift the brain’s focus from stress to bonding.
“Our neuroscience angle is cannabinoids over cortisol,” Kessler told Fox News Digital. “Cannabinoids are the feel-good neurotransmitter in our brain that creates that warm feeling with a friendship — and when you activate cannabinoids, you’re counteracting the negative effects of cortisol, which is our primary stress hormone.”
“Younger adults and older adults tend to experience the highest levels of loneliness of any age group,” the company noted. (Matter Neuroscience)
This isn’t Matter’s first round of payphones. Its initial experiment connected one of the most liberal cities in the U.S. (San Francisco) with one of the most conservative (Abilene, Texas).
“We basically just wanted people to find common ground and encourage people to think beyond labels,” Kessler said.
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She noted that the negative results were “almost negligible,” with most participants enjoying their time speaking to different people.
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Now, the focus has shifted from political labels to generational divides.
The negative results have beem “almost negligible,” with most participants enjoying their time speaking to different people. (Matter Neuroscience)
As the “Call a Boomer” experiment continues, the team is busy collecting audio files of these intergenerational chats to prove that simple connections with other humans can help improve mental health.
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“Our research is essentially trying to find a non-pharmaceutical cure to depression,” Kessler added.
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Looking ahead, she said, “we’ll definitely be doing fun things that we hope get people’s attention and inspire them to learn a little more about themselves.”
Health
Family pleads for help as teen faces life-threatening bone marrow failure
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A New York City father is desperately seeking a donor to save his teenage son’s life.
Max Uribe, now 15 and a high-school freshman, has just weeks until he will need to be hospitalized with a rare blood disorder that could lead to a deadly cancer.
“Max was just 6 when we first noticed there was something wrong with his blood counts,” his father, Juan Uribe, told Fox News Digital. “At the time, we thought it was due to a viral infection, but they never fully recovered back to their normal level.”
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In December 2024, Max’s condition grew worse, and he was diagnosed with clonal cytopenia, a condition involving the blood and bone marrow.
“All three of his blood counts are low — red, white and platelets,” Uribe said.
Max Uribe, pictured with his parents and sister, is in urgent need of a stem cell transplant to save his life. (Uribe Family)
In August 2025, another bone marrow biopsy revealed that Max is on a path to bone marrow failure, creating an urgent need for a stem cell transplant.
“The disease has continued to progress, as his blood counts continue to drop, and therefore, we have to take him to transplant in May of this year,” Uribe said.
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If left untreated, Max’s condition could lead to MDS (myelodysplastic syndrome), a type of blood cancer, and from there possibly into acute myeloid leukemia (AML).
A bone marrow match must have a specific type of HLA (human leukocyte antigen), which are proteins found on the surface of most cells in the body, according to the National Marrow Donor Program (NMDP).
Max Uribe, pictured with his parents, will be hospitalized for a transplant in May, as his blood count has been steadily decreasing. (Uribe Family)
The closer the donor’s HLA markers are to the patient’s, the more likely the body will accept the new cells without a high risk of complications.
People from the same ethnic background are more likely to share similar HLA types, meaning a patient is most likely to find a compatible donor among individuals with similar ancestry, per the NMDP.
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Non-Hispanic White patients have a 79% chance of a perfect match. That drops to 49% for Hispanic/Latino patients, 29% for Black patients and even lower for mixed ancestries, the NMDP reports.
Because Max is a “very rare combination” of half-Colombian from his father and a mix of Italian, British and German from his mother, his path to a perfect match is proving much more difficult, Uribe noted.
“For a kid like Max, with complex, mixed heritage, the math is devastating.”
“For a kid like Max, with complex, mixed heritage, the math is devastating,” he said. “The thinking is, we need large numbers if we’re going to have that perfect match for my son.”
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Max, who participates in competitive tennis and varsity wrestling, just had additional blood work done on Friday, which revealed that his counts continue to plummet.
“We’re at the point where this is beginning to manifest a bit more, which is why the urgency is so critical,” Uribe said.
Because Max is a “very rare combination” of half-Colombian from his father and a mix of Italian, British and German from his mother, his path to a perfect match is proving much more difficult. (Uribe Family)
If a donor is not secured by Max’s hospitalization in May, the medical team will have to proceed with a partial match, which is not ideal for a number of reasons.
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“The survival rate is meaningfully lower with a partial match, and there’s more risk of graft versus host disease (GVHD), which could lead to complications in the process,” Uribe said. With GVHD, the donor cells begin to attack the body.
Max Uribe, an active athlete, is on a path to bone marrow failure, requiring a stem cell transplant. (Uribe Family)
To help prevent this with a partial match, Max would likely need chemotherapy and immunosuppressants for a longer period of time, which could weaken his immune system.
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Anyone interested in donating can order a free test kit on the Team Max website. The kit includes a quick cheek swab that is sent back to the lab to determine whether someone is a match.
Health
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