Health
Heart attack and stroke risk may rise after COVID infection, study finds
A prior COVID infection could make you more susceptible to heart attack, stroke or death, according to a new study from Cleveland Clinic and the University of Southern California.
The risk of a major cardiac event doubled for the three-year period following a positive COVID test, researchers found — even for those with no history of heart disease.
The researchers analyzed data from 10,005 people 50 and older who had COVID and 217,730 who did not contract the virus, pulled from UK Biobank between February and December 2020.
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The study, which was funded by the National Institutes of Health, was published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology.
A prior COVID infection could make you more susceptible to heart attack, stroke or death, according to a new study. (iStock)
“These studies add to the growing body of data showing that COVID-19 infection can enhance risk for experiencing adverse cardiac events over time,” co-senior study author Stanley Hazen, MD, PhD, chair of cardiovascular and metabolic sciences in Cleveland Clinic’s Lerner Research Institute and co-section head of preventive cardiology, told Fox News Digital.
The researchers were surprised to find that the increased risk remained the same over the three-year period.
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“The twofold increased risk observed in year one following infection was also seen in year two and even year three,” Hazen noted.
“This was seen in all subjects, independent of age, sex or risk factors for cardiac disease.”
Those who had more adverse symptoms experienced a slightly higher risk than those with milder symptoms.
The researchers were surprised to find that the increased risk remained the same over the three-year period. (iStock)
“Specifically, subjects who had severe COVID-19 infection and required hospitalization were at even higher risk of experiencing a major adverse cardiac event (MACE=myocardial infarction, stroke or death) over the ensuing three years of follow-up,” Hazen said.
Blood type also appeared to impact the risk, the study found.
People with a blood type other than O — such as A, B or AB — had double the risk of a major cardiac event than those with an O blood type.
“This study confirms what many of us have seen anecdotally over the past five years.”
Those with O blood have also been shown to have a higher likelihood of getting a COVID infection.
“Given our collective observations and that 60% of the world’s population have these non-O blood types, our study raises important questions about whether more aggressive cardiovascular risk reduction efforts should be considered, possibly by taking into consideration an individual’s genetic makeup,” Hazen said in a press release.
Based on these findings, the researchers recommend that medical providers consider COVID-19 as a risk factor for heart disease. (iStock)
Dr. Bradley Serwer, a cardiologist and chief medical officer at VitalSolution, a Cincinnati, Ohio-based company that offers cardiovascular and anesthesiology services to hospitals nationwide, was not involved in the research but commented on the “interesting” findings.
“This study confirms what many of us have seen anecdotally over the past five years,” he told Fox News Digital.
“Since the outbreak began, we have seen cardiac complications to include inflammation of the heart, a propensity to form blood clots and an increase in abnormal heart rhythms, particularly atrial fibrillation.”
“The lead author, Dr. Hazen, has some fascinating theories that I assume will be tested in the future.”
Reducing the risk
Based on these findings, Hazen recommends that medical providers consider COVID-19 as a risk factor for heart disease.
“Heart disease is the number one killer worldwide,” he noted.
People with a blood type other than O — such as A, B or AB — had double the risk of a major cardiac event than those with an O blood type. (iStock)
“With over a billion individuals worldwide having experienced COVID-19 thus far, these studies argue that this is not a small problem — and I hope this serves as a reminder to address global preventive cardiovascular risk-reducing efforts.”
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Among those efforts are monitoring cholesterol levels and blood pressure, adopting an exercise program, and being more mindful of diet.
Doctors recommend monitoring cholesterol levels and blood pressure, adopting an exercise program, and being more mindful of diet to reduce risk. (iStock)
“Please let this study be a reminder — if you are 50 or older and have experienced COVID, ask if you can do anything further to reduce your cardiac risk,” Hazen advised.
“Also, make sure to stay current with your COVID-19 vaccinations and boosters.”
More research needed, experts agree
The study did have some limitations, experts acknowledged.
“These findings signal the need for further investigation,” Hazen said.
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“A better understanding of what COVID-19 does at the molecular level may potentially teach us about pathways linked to cardiovascular disease risk.”
Serwer agreed, adding, “This study shows an association, but does not prove causality.”
Health
Common nighttime noise exposure may trigger heart problems, study suggests
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Living near heavy traffic could negatively impact your heart health.
A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.
The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.
Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)
The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.
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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.
The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”
Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)
Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”
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“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.
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“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”
This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.
“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)
“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”
The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”
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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”
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The researcher noted that these findings were consistent across genders, education levels and obesity status.
The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.
Changes in cholesterol levels were more severe than researchers expected. (iStock)
“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”
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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.
“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”
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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”
Experts recommend taking measures to limit traffic noise at night. (iStock)
Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”
“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”
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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.
“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.
Health
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