Health
Feeling extra tired? This virus could be the culprit, study suggests
People who have had COVID-19 are more likely to develop chronic fatigue syndrome, officially known as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
That’s according to a study published in the Journal of General Internal Medicine earlier this month, which found that 4.5% of people infected with SARS-CoV-2, the virus that causes COVID, developed chronic fatigue.
In comparison, only 0.6% of study participants who did not have COVID developed the second condition.
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The researchers determined that cases of ME/CFS were 15 times higher than pre-pandemic levels.
People who have had COVID-19 are more likely to develop chronic fatigue syndrome, officially known as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (iStock)
“As a researcher dedicated to understanding how viral infections lead to chronic illness, I suspected from the beginning of the pandemic that SARS-CoV2 could trigger ME/CFS, so these results are not surprising,” said lead study author Suzanne D. Vernon, PhD, from the Bateman Horne Center in Salt Lake City.
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The study was part of the National Institute of Health’s RECOVER (Researching COVID to Enhance Recovery) program, which aims to better understand, prevent and treat long COVID, according to an NIH press release.
The study included 11,785 participants. At least six months after they were infected with COVID, researchers assessed whether they had developed chronic fatigue. They then compared those results to 1,439 people who did not have COVID.
The researchers determined that cases of ME/CFS were 15 times higher than pre-pandemic levels. (iStock)
“There are no specific tests or biomarkers, so ME/CFS is diagnosed when someone has a constellation of specific symptoms,” Vernon told Fox News Digital.
“This study asked participants questions to determine what symptoms they were experiencing, which can be viewed as a limitation but is currently the approach used to diagnose ME/CFS.”
“It’s well-known that chronic fatigue syndrome can occur in the setting of viral infections.”
Dr. Kenneth J. Perry, a physician based in South Carolina, wasn’t surprised by the incidence of chronic fatigue after a SARS-CoV-2 infection.
“It’s well-known that chronic fatigue syndrome can occur in the setting of viral infections,” Perry, who was not involved in the research, told Fox News Digital.
“Given the fact that SARS-CoV-2 was a novel virus at the time of the pandemic, the incidence and prevalence of such post-infection syndromes was difficult to predict.”
“It’s well-known that chronic fatigue syndrome can occur in the setting of viral infections,” a physician told Fox News Digital. (iStock)
The study does have some limitations when attempting to compare between different viruses, the doctor noted.
“Patients were required to self-report their symptoms,” he said. “This makes the ability to compare symptoms across viruses difficult, as the spotlight on COVID will increase the possibility of selection bias.”
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It’s difficult to specifically determine how chronic fatigue happens in the setting of a viral infection, according to Perry.
“More studies would have to be done to determine the actual underlying pathophysiology of the disease,” he said. “Given that lack of complete understanding, it is difficult to determine how to adequately prevent the syndrome.”
What to know about chronic fatigue
ME/CFS is a “complex, serious and chronic condition that often occurs following an infection,” the NIH wrote.
The condition is marked by “new-onset fatigue” that lasts for at least six months and impairs the person’s ability to engage in ordinary activities.
“There are both physical and psychological components to the syndrome.”
Another symptom is “post-exertional malaise,” in which the person feels extreme fatigue after physical or mental activity, the study stated.
People with ME/CFS may also experience “unrefreshing sleep,” as well as cognitive impairment or dizziness when standing.
Many of these symptoms are also associated with long COVID, the researchers wrote.
“Chronic fatigue syndrome can be very problematic for patients,” Perry told Fox News Digital. “There are both physical and psychological components of the syndrome.”
“Having a relationship with a physician who knows your baseline activity level is going to ensure an appropriate evaluation and intervention if there are any changes,” a doctor advised. (iStock)
Perry reiterated that patients can experience direct fatigue and a decreased ability to do normal activities — and this can also lead to anxiety and depression due to these changes.
“It is very difficult to adequately understand the difference between chronic fatigue syndrome and … underlying psychiatric/psychological health changes,” he said. “This makes it a very difficult disease to explain for patients.”
‘Urgent call to action’
Those experiencing symptoms of chronic fatigue should contact their primary care doctor, Perry advised.
“Having a relationship with a physician who knows your baseline activity level is going to ensure an appropriate evaluation and intervention if there are any changes,” he said.
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“For example, a triathlete who can no longer even stay awake through the entirety of a workday would absolutely be concerning to a physician who knows that patient well. This relationship would also allow for appropriate medications and therapies to be initiated earlier in the process.”
“The dramatic increase in ME/CFS cases post-COVID-19 means that providers will encounter this condition far more frequently,” the researcher said. (iStock)
This research underscores an “urgent call to action,” Vernon said — “especially to healthcare providers.”
“The dramatic increase in ME/CFS cases post-COVID-19 means that providers will encounter this condition far more frequently,” she predicted.
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The researcher called for early recognition and proper management of ME/CFS, which she said can be “life-changing” for patients.
“We hope this study helps everyone understand that ME/CFS is a real and diagnosable condition that demands attention, especially in the wake of a global pandemic.”
New flu strain emerging as a severe health threat
Fox News senior medical analyst Dr. Marc Siegel joins ‘America’s Newsroom’ to warn of a new strain of the flu that is spiking hospitalizations across the country and newfound risks of medical marijuana’s link to psychosis.
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The New York State Department of Health reported a record surge in influenza activity, with 71,123 positive flu cases recorded statewide during the week ending December 20.
Health officials said the figure represents the highest number of flu cases ever reported in a single week since influenza became a reportable disease in New York in 2004.
State health data show the weekly total reflects a 38% increase from the previous reporting period, signaling a rapidly intensifying flu season.
There have been 189,312 reported positive flu cases so far this season, while influenza-related hospitalizations rose 63% in the most recent week.
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New York reported the highest weekly total of cases ever recorded since influenza became reportable in 2004. (iStock)
“We are seeing the highest number of flu cases ever recorded in a single week in New York state,” Health Commissioner Dr. James McDonald said in a press release.
There have been 189,312 reported flu cases so far this season, with influenza-related hospitalizations increasing 63% in the most recent week. (iStock)
Earlier this month, the department declared influenza prevalent statewide, a designation that requires unvaccinated health care workers to wear masks in patient care settings.
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Health officials continue to emphasize that vaccination remains the most effective way to prevent severe illness and hospitalization from influenza.
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New Yorkers who have not yet received a seasonal flu shot are still encouraged to do so, with experts saying vaccination can offer protection even later in the season.
Health officials continue to urge New Yorkers to take preventive steps, including vaccination and staying home when sick, to limit further spread. (iStock)
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To help limit further spread, the department advises individuals experiencing flu-like symptoms — including fever, cough, sore throat, or body aches — to stay home. State health officials also recommend frequent handwashing, using hand sanitizer, and avoiding close contact with sick individuals.
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For those who become ill, officials say antiviral medications are available and are most effective when started within 48 hours of symptom onset.
Health officials also added that people at higher risk for complications should contact a health care provider promptly for evaluation and possible treatment.
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The department noted that flu activity typically peaks in January, meaning case counts could continue to climb in the weeks ahead.
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If the stress of the holidays wreaked havoc on your gut, you’re not alone — 76% of Americans experience gastrointestinal distress during the holiday season, according to a recent national survey from Oshi Health and YouGov.
Digestive problems can be triggered not only by holiday overeating, but also by stress. Financial worries, disrupted routines, fatigue and interpersonal dynamics rank as some of the top causes.
“I see an uptick in psychiatry-related GI issues during the holiday season,” Dr. Claire Brandon, a gastrointestinal psychiatrist based in New York City, told Fox News Digital. “When you are undergoing stress, your body produces more corticotropin-releasing hormones, which sets off a cascade of the inflammatory system.”
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Stress hormones can act directly on the gut, leading to more digestive distress and pushing the body out of “rest-and-digest mode,” Brandon said.
“Stress activates the sympathetic — fight, flight, freeze — nervous system, which slows digestion,” added Dr. David Clarke, an Oregon-based gastroenterologist and president of the Association for the Treatment of Neuroplastic Symptoms. “That can lead to bloating, cramps, nausea and sometimes abdominal pain.”
Stress often plays a bigger role in digestive issues than overeating alone, experts say. (iStock)
The good news, doctors say, is that a few simple, realistic steps can help reset the digestive system after the holidays.
No. 1: Reset your sleep
Sleep plays a major role in gut health. Research shows that insufficient or disrupted sleep can change the composition and function of the gut microbiome, potentially affecting metabolic and immune factors that influence overall health.
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“When I travel and get derailed, my main focus is to reset my sleep,” Brandon said. She recommends reestablishing wind-down routines like deep breathing and progressive muscle relaxation.
No. 2: Eat balanced, fiber-rich meals
Fiber helps keep digestion moving and supports healthy gut bacteria, which can aid post-holiday recovery, experts say.
“The usual principles for supporting digestion apply here,” said Clarke. “Consuming a balanced diet emphasizing fruits, vegetables, whole grains and legumes; avoiding highly processed foods; and moderating alcohol will keep your gut microbiome happy.”
Digestive symptoms like bloating and discomfort often spike during the holidays due to stress, travel and disrupted routines. (iStock)
No. 3: Stay hydrated
Staying hydrated will also aid digestion, Clarke said, noting that light-colored urine is a good indicator of hydration.
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Traveling can be particularly tough on the gut, experts say, especially during flights where low cabin humidity causes the body to pull water from the bowels, leading to constipation.
Drinking water before, during, and after flights — and limiting alcohol and caffeine — can help counteract dehydration-related digestive slowdowns. Experts also recommend sipping water consistently throughout the day.
No. 4: Resume regular movement
Both doctors agreed that exercise supports digestion and stress regulation, which are both key to gut recovery.
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“Going on walks can be enough to help with this, but if you have space to do more, including some gentle stretching, that can be a huge help,” Brandon advised.
No. 5: Reduce stress gradually
Stress management plays a critical role in gut health, and experts say that small, consistent habits can help ease gastrointestinal symptoms.
Brandon recommends calming the nervous system with breathing or grounding exercises and slowing down at meals.
Light movement can help support digestion and regulate stress, experts say. (iStock)
“If you’re constantly running on fumes, on a layover in the airport, eating high sugar and doing things off your routine, expect a few disruptions with your gut,” she said. “Reframe it as something that you can reset when you get home.”
No. 6: Skip cleanses and detoxes
Clarke says that detoxes and cleanses are not necessary and can actually be harmful. Instead, he recommends sticking to the basics — including hydration, balanced meals, regular sleep and movement.
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Doctors say the gut is designed to recover on its own in response to consistently healthy practices rather than extreme resets.
Experts recommend returning to balanced, fiber-rich meals instead of intense cleanses. (iStock)
While short-lived symptoms can improve within hours and are usually temporary, experts say lingering or worsening issues shouldn’t be ignored.
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“If you are back home and struggling to feel your usual baseline while back on your routine, it’s probably worth checking in with your physician,” Brandon advised.
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Regular exercise may do more than strengthen the heart. It could also reprogram the nerves that control how the heart beats, new research has found.
The discovery could eventually help doctors better treat common conditions such as irregular heart rhythms, chest pain, angina and stress-related “broken-heart” syndrome, according to scientists at the University of Bristol in the U.K.
The study, which looked at lab rats trained over 10 weeks, found that moderate exercise does not affect the heart’s nerve control system evenly. Instead, it produces distinct and opposing changes on the left and right sides of the body. a split researchers say has gone largely unnoticed until now.
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“The discovery points to a previously hidden left–right pattern in the body’s ‘autopilot’ system that helps run the heart,” Dr. Augusto Coppi, the study’s lead author and a senior lecturer in veterinary anatomy at the University of Bristol, said in a statement.
Regular exercise may “rewire” the nerves that control the heart, the new study found. (iStock)
“This could help explain why some treatments work better on one side than the other and, in the future, help doctors target therapies more precisely and effectively,” Coppi added.
After 10 weeks of aerobic exercise, the researchers examined the animals’ heart control nerves and found left–right differences that did not appear in inactive rats, according to the research published in the journal Autonomic Neuroscience in September.
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On the right side, the nerve hub that sends “go faster” signals to the heart developed many more nerve cells, suggesting increased wiring. On the left side, however, the number of nerve cells did not rise as much. Instead, the existing cells grew significantly larger, indicating a different kind of adaptation.
The findings could help explain why some heart treatments work better on one side than the other. (iStock)
The findings show that exercise reshapes the heart’s nerve control system in a side-specific way rather than affecting both sides equally, the researchers said. Understanding that process could help doctors better target treatments, especially for patients who cannot exercise or whose symptoms persist despite lifestyle changes.
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Researchers compared the nerve clusters, known as the stellate ganglia, to a “dimmer switch” that fine-tunes how strongly the heart is stimulated. That fine-tuning is important because overstimulation of these nerves is linked to chest pain and dangerous heart rhythm problems.
Scientists caution more studies are needed to determine whether the same effects occur in humans. (iStock)
The findings are early stage and based on animal research, however. So, they do not prove the same effects in people. More studies are needed before they could affect patient care.
Researchers say future studies will explore whether similar left–right nerve changes occur in people and whether they could help explain why some heart treatments work better on one side than the other, potentially paving the way for more precise, personalized care for angina and heart rhythm disorders.
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The study was conducted in collaboration with researchers from University College London, the University of São Paulo and the Federal University of São Paulo in Brazil.
Researchers discovered distinct left-right changes in heart-control nerves after 10 weeks of aerobic exercise. (iStock)
The findings add to growing evidence that regular, moderate exercise benefits the heart in ways scientists are beginning to understand better.
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Fox News Digital has reached out to the study authors for comment.
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