Health
Fatal bacterial infections surging in Japan with unknown cause, reports says
Japan is reporting a spike in potentially fatal bacterial infections.
Cases of streptococcal toxic shock syndrome (STSS), which is caused by Group A Streptococcus bacteria, have reached 977 in the country so far this year as of June 2, according to Japan’s National Institute of Infectious Diseases.
That is almost triple the number of cases reported at this time last year.
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The cause for the surge is not known.
It could be linked to weakened immunity after the COVID pandemic, according to Tokyo Women’s Medical University professor Ken Kikuchi.
“We can boost immunity if we are constantly exposed to bacteria, but that mechanism was absent during the coronavirus pandemic,” Kikuchi told NKH World Japan.
“So, more people are now susceptible to infection, and that may be one reason for the sharp rise in cases.”
“It can lead to sepsis and death if not treated quickly with antibiotics and fluids.”
Thomas Moore, M.D., a clinical professor at the University of Kansas School of Medicine-Wichita, said he’s not convinced the pandemic is the culprit.
“I can’t conclusively say that that’s incorrect, but this is the kind of thing where it spreads more easily when people are crowded together, like they can be in Tokyo,” he said in an interview with Fox News Digital.
“So it’s not so much an effect of weakened immunity as much as it is a very brisk immunity — a brisk immunologic reaction that results in the illness.”
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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, warned that STSS can overcome an immune system that isn’t functioning properly.
“It’s similar to toxic shock syndrome, but with strep instead of staph,” he told Fox News Digital.
What is STSS?
Streptococcal toxic shock syndrome is a rare but serious bacterial infection, as defined by the U.S. Centers for Disease Control and Prevention (CDC).
It occurs when the Group A Streptococcus bacteria travels into deep tissues and the bloodstream.
“Everybody’s familiar with strep throat, and that’s generally the same organism,” said Moore.
“The main difference between common, regular strep throat and this particular condition is a specific gene that produces a toxin that results in this severe outbreak.”
Although STSS usually does not spread from person to person, the less severe group A strep infection — which can lead to STSS if it spreads to the tissues or bloodstream — is very contagious.
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Initial symptoms usually include fever and chills, muscle aches, and nausea and vomiting, per the CDC.
Within a day or two, blood pressure starts to drop, which can lead to more dangerous effects like elevated heart rate, rapid breathing, sepsis, tissue death and organ failure.
STSS can be fatal, with about one in 10 patients dying from the infection.
Although there is no specific test for STSS, it is diagnosed based on the presence of group A strep, low blood pressure and issues with two or more organs (blood, kidney, liver, lung, skin or soft tissue).
Higher-risk groups include older adults over 65, people with open wounds, and those with diabetes or alcohol use disorder, according to the CDC.
People with STSS require hospitalization and immediate medical care, including intravenous fluids and other treatments for shock and organ failure, the agency stated on its website.
“It can lead to sepsis and death if not treated quickly with antibiotics and fluids,” Siegel warned.
In severe cases, he said, patients may require surgery to remove infected tissue or even limb amputation.
Prevention tips
Although there is no vaccine for Group A strep infections, the CDC recommends implementing prevention tips — chiefly limiting exposure to those who are infected.
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It is also important to properly clean and care for wounds and fungal infections.
“If it gets on your skin where you have a break of some kind, it can invade the lymphatic system and cause infection,” Moore warned.
The doctor typically sees this in people who have swelling of their legs due to obesity, diabetes or a condition such as athlete’s foot, he said.
“When streptococcal infection gets in through other parts of the body, like the legs or a surgical incision, that can be pretty serious,” he said.
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Frequently washing hands, following proper coughing and sneezing etiquette, and thoroughly washing all dishes after use can help prevent spread, per the CDC.
Treatment with antibiotics also minimizes contagion.
Health
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Health
One state leads country in human bird flu with nearly 40 confirmed cases
A child in California is presumed to have H5N1 bird flu, according to the San Francisco Department of Public Health (SFDPH).
As of Dec. 23, there had been 36 confirmed human cases of bird flu in the state, according to the California Department of Public Health (CDPH).
This represents more than half of the human cases in the country.
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The latest pediatric patient, who lives in San Francisco, experienced fever and conjunctivitis (pink eye) as a result of the infection.
The unnamed patient was not hospitalized and has fully recovered, according to the SFDPH.
The child tested positive for bird flu at the SFDPH Public Health Laboratory. The U.S. Centers for Disease Control and Prevention (CDC) will perform additional tests to confirm the result.
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It is not yet known how the child was exposed to the virus and an investigation is ongoing.
“I want to assure everyone in our city that the risk to the general public is low, and there is no current evidence that the virus can be transmitted between people,” said Dr. Grant Colfax, director of health, in the press release.
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“We will continue to investigate this presumptive case, and I am urging all San Franciscans to avoid direct contact with sick or dead birds, especially wild birds and poultry. Also, please avoid unpasteurized dairy products.”
Samuel Scarpino, director of AI and life sciences and professor of health sciences at Northeastern University in Boston, is calling for “decisive action” to protect individuals who may be in contact with infected livestock and also to alert the public about the risks associated with wild birds and infected backyard flocks.
“While I agree that the risk to the broader public remains low, we continue to see signs of escalating risk associated with this outbreak,” he told Fox News Digital.
Experts have warned that the possibility of mutations in the virus could enable person-to-person transmission.
“While the H5N1 virus is currently thought to only transmit from animals to humans, multiple mutations that can enhance human-to-human transmission have been observed in the severely sick American,” Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, told Fox News Digital.
“This highlights the requirement for vigilance and preparation in the event that additional mutations create a human-transmissible pandemic strain.”
As of Jan. 10, there have been a total of 707 infected cattle in California, per reports from the California Department of Food and Agriculture (CDFA).
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In the last 30 days alone, the virus has been confirmed in 84 dairy farms in the state.
Health
Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.
“In the beginning, everyone thought they were going to find this one breakthrough pain drug that would replace opioids,” Gereau said. Increasingly, though, it’s looking like chronic pain, like cancer, could end up having a range of genetic and cellular drivers that vary both by condition and by the particular makeup of the person experiencing it. “What we’re learning is that pain is not just one thing,” Gereau added. “It’s a thousand different things, all called ‘pain.’”
For patients, too, the landscape of chronic pain is wildly varied. Some people endure a miserable year of low-back pain, only to have it vanish for no clear reason. Others aren’t so lucky. A friend of a friend spent five years with extreme pain in his arm and face after roughhousing with his son. He had to stop working, couldn’t drive, couldn’t even ride in a car without a neck brace. His doctors prescribed endless medications: the maximum dose of gabapentin, plus duloxetine and others. At one point, he admitted himself to a psychiatric ward, because his pain was so bad that he’d become suicidal. There, he met other people who also became suicidal after years of living with terrible pain day in and day out.
The thing that makes chronic pain so awful is that it’s chronic: a grinding distress that never ends. For those with extreme pain, that’s easy to understand. But even less severe cases can be miserable. A pain rating of 3 or 4 out of 10 sounds mild, but having it almost all the time is grueling — and limiting. Unlike a broken arm, which gets better, or tendinitis, which hurts mostly in response to overuse, chronic pain makes your whole world shrink. It’s harder to work, and to exercise, and even to do the many smaller things that make life rewarding and rich.
It’s also lonely. When my arms first went crazy, I could barely function. But even after the worst had passed, I saw friends rarely; I still couldn’t drive more than a few minutes, or sit comfortably in a chair, and I felt guilty inviting people over when there wasn’t anything to do. As Christin Veasley, director and co-founder of the Chronic Pain Research Alliance, puts it: “With acute pain, medications, if you take them, they get you over a hump, and you go on your way. What people don’t realize is that when you have chronic pain, even if you’re also taking meds, you rarely feel like you were before. At best, they can reduce your pain, but usually don’t eliminate it.”
A cruel Catch-22 around chronic pain is that it often leads to anxiety and depression, both of which can make pain worse. That’s partly because focusing on a thing can reinforce it, but also because emotional states have physical effects. Both anxiety and depression are known to increase inflammation, which can also worsen pain. As a result, pain management often includes cognitive behavioral therapy, meditation practice or other coping skills. But while those tools are vital, it’s notoriously hard to reprogram our reactions. Our minds and bodies have evolved both to anticipate pain and to remember it, making it hard not to worry. And because chronic pain is so uncomfortable and isolating, it’s also depressing.
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