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Aging-related joint disorder increasingly affects people under 40, study finds

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Aging-related joint disorder increasingly affects people under 40, study finds

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Cases of gout are rising in younger individuals, according to a global study.

The condition, which is a type of inflammatory arthritis, steadily increased in people aged 15 to 39 between 1990 and 2021, researchers in China announced.

Although rates vary widely between countries, the total number of young people with the condition is expected to continue rising through 2035.

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The study, published in the journal Joint Bone Spine, investigated 2021 data from the Global Burden of Disease (GBD), spanning 204 countries within the 30-year timeframe.

The data measured gout prevalence, incidence and years lived with disability, tracking global trends over time. The results showed a global increase across all three outcomes.

Gout is expected to continue rising in young people through 2035. (iStock)

Prevalence and disability years increased by 66%, and incidence rose by 62%. In 2021, 15- to 39-year-olds accounted for nearly 14% of new gout cases globally, the study found.

Men from 35 to 39 years old and people in high-income regions had the highest burden, but high-income North America topped the list for highest rates.

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Men were also found to have lived more years with gout due to high BMI, while women tended to have the condition as a link to kidney dysfunction, the study noted.

The total number of cases is expected to increase globally due to population growth, but the study projected that rates per population would decrease.

The researchers noted that data quality, especially in low-income settings, could have posed a limitation to the broad GBD data.

What is gout?

Gout is a common form of arthritis involving sudden and severe attacks of pain, swelling, redness and tenderness in the joints, according to Mayo Clinic. It most often occurs in the big toe.

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The condition occurs when urate crystals accumulate in the joint. These form when there are high levels of uric acid in the blood, which the body produces when it breaks down a natural substance called purines.

A gout flare-up can happen at any time, often at night, causing the affected joint to feel hot, swollen, tender and sensitive to the touch.

Urate crystals, described as sharp and needle-like, build up in the joint, causing intense pain and swelling. (iStock)

Purines can also be found in certain foods, like red meat or organ meats like liver and some seafood, including anchovies, sardines, mussels, scallops, trout and tuna, according to the Mayo Clinic. Alcoholic drinks, especially beer, and drinks sweetened with fruit sugar can also lead to higher uric acid levels.

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Uric acid will typically dissolve in the blood and pass through the kidneys into urine, but when the body produces too much or too little uric acid, it can cause a build-up of urate crystals. These are described by the Mayo Clinic as sharp and needle-like, causing pain, inflammation and swelling in the joint or surrounding tissue.

Risk factors for gout include a diet rich in high-purine foods and being overweight, which causes the body to produce more uric acid and the kidneys to have trouble eliminating it.

Experts urge patients to seek medical attention for gout flare-ups. (iStock)

Certain conditions like untreated high blood pressure, diabetes, obesity, metabolic syndrome and heart and kidney diseases can increase the risk of gout, as well as certain medications.

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A family history of gout can also increase risk. Men are more likely to develop the condition, as women tend to have lower uric acid levels, although symptoms generally develop after menopause.

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Untreated gout can cause worsening pain and joint damage, experts caution. It may also lead to more severe conditions, such as recurrent gout, advanced gout and kidney stones.

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The Mayo Clinic advises patients to seek immediate medical care if a fever occurs or if a joint becomes hot and inflamed, which is a sign of infection. Certain anti-inflammatory medications can help treat gout flares and complications.

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Fox News Digital reached out to the researchers for comment.

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Tick bite ER visits hit highest seasonal level in years as doctors warn of disease surge

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Tick bite ER visits hit highest seasonal level in years as doctors warn of disease surge

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Tick bite-related ER visits are at their highest seasonal levels since 2017 across most U.S. regions, raising concerns about increased Lyme disease and other tick-borne illnesses.

That’s according to recent data from the Centers for Disease Control and Prevention’s Tick Bite Tracker, which monitors weekly emergency department visits associated with tick bites across the country.

For every 100,000 ER visits, approximately 71 were related to tick bites in April 2026, compared to a historical seasonal average of roughly 30 per 100,000.

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Some of the highest rates of tick-based ER visits were among children younger than 10 years and adults between 70 and 79 years.

A close-up shows a parasitic mite in motion on a human fingertip, highlighting the potential for disease transmission such as encephalitis. (iStock)

“Over the past three decades, the geographic range of the blacklegged tick has expanded significantly, and with it, the risk of Lyme disease and other Ixodes-transmitted infections,” Dr. Steven Goldberg, a family medicine physician who practices urgent care and family medicine at UofLHealth in Louisville, Kentucky, told Fox News Digital.

‘RABBIT FEVER’ CASES RISING IN US AS CDC WARNS OF ZOONOTIC BACTERIAL DISEASE

“The Ohio River Valley region is one of the most striking examples — Lyme disease cases in Ohio have increased roughly 10-fold over the past decade, likely driven by the convergence of Northeastern and Upper Midwestern tick populations meeting in that corridor.”

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States like Virginia and West Virginia, as well as areas south of the traditional endemic zone, are reporting increasing tick abundance and disease cases, the doctor noted.

“Over the past three decades, the geographic range of the blacklegged tick has expanded significantly.”

“The lone star tick is also expanding its range northward beyond its traditional stronghold in the Southeast, which means diseases like ehrlichiosis and alpha-gal syndrome are appearing in regions where clinicians may not yet be thinking about them,” he warned.

Some climate studies predict that the blacklegged tick’s suitable habitat could expand by over 200% by the end of the century, Goldberg noted, including into Canada and across the central and southern U.S.

What’s driving the spike?

“Warmer, wetter conditions allow ticks to survive in habitats that previously would have been too cold,” said Dr. Suraj Saggar, chief of infectious disease at Holy Name Medical Center in Teaneck, New Jersey. “Milder winters also extend the lifespan of both ticks and the animals they feed on, accelerating tick reproduction and shortening their life cycles.”

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Areas that historically experienced longer, colder winters or significant snow cover are now more hospitable to ticks, the doctor noted.

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“As temperatures rise and precipitation patterns change, ticks are able to spread northward and thrive in new ecosystems,” he said. 

Another contributing factor is increased land development and human expansion into wooded and grassy areas, as well as reforestation of formerly agricultural land.

“As temperatures rise and precipitation patterns change, ticks are able to spread northward and thrive in new ecosystems,” an expert said.  (iStock)

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“The recovery and expansion of white-tailed deer populations — critical hosts for adult blacklegged ticks — has been a major driver,” Goldberg added. “Deer density is positively associated with Lyme disease incidence. Small mammal communities, particularly white-footed mice that serve as key reservoir hosts for Borrelia burgdorferi, also play a central role.”

Tick-borne diseases

Tick bites are known to transmit numerous illnesses, the most widespread of which is Lyme disease, a bacterial infection.

“Lyme disease cases alone have increased roughly two- to threefold over the past 20 years,” Saggar said. Approximately 476,000 Americans are diagnosed and treated for Lyme disease each year, per CDC surveillance data.

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Also common are anaplasmosis and ehrlichiosis, two different types of bacterial infections, according to the doctor. Tick bites can also cause babesiosis, a malaria-like parasitic disease that infects and destroys red blood cells.

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“Another growing concern is alpha-gal syndrome, a condition in which a (lone star) tick bite triggers a serious allergic reaction to red meat,” Saggar said. “In rare cases, people have died from anaphylactic reactions linked to alpha-gal syndrome following a tick bite.”

Some common symptoms of tick-borne illness include fever, chills, fatigue, headaches, muscle aches and joint pain. (iStock)

Ticks can also transmit viruses, including the Powassan virus, which can cause severe neurologic injury.

“Powassan virus disease is arguably the most concerning emerging tick-borne infection,” said Goldberg, who is also chief medical officer at HealthTrack. “It’s transmitted by the same blacklegged tick that carries Lyme disease, but unlike Lyme, it can be transmitted within minutes of tick attachment.”

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Powassan can cause severe encephalitis with a roughly 10% to 15% fatality rate, and more than half of survivors have lasting neurological deficits, Goldberg noted.

In the Rocky Mountain states, the Rocky Mountain wood tick (Dermacentor andersoni) transmits Rocky Mountain spotted fever and Colorado tick fever.

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“In the Southeast and South-Central U.S., the lone star tick (Amblyomma americanum) drives a different set of concerns: ehrlichiosis, tularemia, and two emerging viral threats — Heartland virus and Bourbon virus,” said Goldberg.

Symptoms to watch for

Some common symptoms of tick-borne illness include fever, chills, fatigue, headaches, muscle aches and joint pain, according to Saggar.

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Another sign is the classic “bull’s-eye” rash associated with Lyme disease, known medically as “erythema migrans.” 

“If you think you have been bitten by a tick, you should seek medical attention if you develop symptoms after a known tick bite or after spending time in tick-prone areas, especially during the spring, summer and fall.” (iStock)

“Because testing can sometimes be falsely negative early in the disease process, doctors may treat patients based on symptoms and exposure history rather than waiting for laboratory confirmation,” Saggar noted. 

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“If you think you have been bitten by a tick, you should seek medical attention if you develop symptoms after a known tick bite or after spending time in tick-prone areas, especially during the spring, summer and fall.”

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Preventing tick bites

As there are no vaccines currently available for any tick-borne disease in the U.S., prevention is the most effective strategy.

Goldberg shared the following recommended prevention strategies.

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  • Use EPA-approved repellents, including DEET, picaridin, IR3535 or oil of lemon eucalyptus on exposed skin. Treat clothing and gear with permethrin (a synthetic insecticide and repellent) or purchase pre-treated clothing.
  • Wear light-colored clothing (to spot ticks more easily), long sleeves and long pants tucked into socks when in wooded or grassy areas.
  • After spending time outdoors, check your entire body, paying special attention to the scalp, behind the ears, armpits, groin and behind the knees, the doctor advised. It’s also recommended to shower within two hours of coming indoors.
  • Tumble-dry clothing on high heat for at least 10 minutes to kill any ticks on clothing.
  • Remove ticks promptly and properly. Using fine-tipped tweezers, grasp the tick as close to the skin as possible, and pull upward with steady, even pressure. Clean the bite area afterward.

Approximately 476,000 Americans are diagnosed and treated for Lyme disease each year, per CDC data.

“The longer a tick is attached, the higher the risk of disease transmission — for Lyme disease, transmission generally requires at least 36 hours of attachment,” Goldberg said. “The Powassan virus can be transmitted much more quickly.”

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How Author Mary Kay Andrews, 71, Lost 65 Lbs. Microdosing GLP-1 Meds

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How Author Mary Kay Andrews, 71, Lost 65 Lbs. Microdosing GLP-1 Meds


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How Microdosing a GLP-1 Helped Mary Kay Andrews Lose Weight




















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What to know about thyroid cancer prognosis following Pam Bondi’s diagnosis

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What to know about thyroid cancer prognosis following Pam Bondi’s diagnosis

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Former Attorney General Pam Bondi was diagnosed with thyroid cancer shortly after leaving the Department of Justice last month, according to a report.

Bondi, 60, who left her role at the Justice Department in early April, underwent treatment and is recovering, a source stated.

The thyroid is a gland located in the neck. It makes hormones that are then secreted into the blood, which help the body “use energy, stay warm and keep the brain, heart, muscles and other organs working as they should,” according to the American Thyroid Association.

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Thyroid cancer is relatively uncommon compared to other cancers. Even so, as of 2023, more than one million people in the U.S. are living with the disease.

The National Cancer Institute (NCI) predicts that there will be an estimated 45,260 new cases in 2026.

Former Attorney General Pam Bondi was diagnosed with thyroid cancer shortly after leaving the Department of Justice last month. (Alex Wong/Getty Images)

Risk factors and symptoms

While more common in women, thyroid cancer can affect both sexes. Those with a family history may be more likely to develop it, as well as those between the ages of 25 and 65. Exposure to radiation is also a risk factor, according to the National Cancer Institute.

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Signs of thyroid cancer may include lumps or swelling in the neck, trouble breathing, trouble swallowing, hoarseness and pain when swallowing, per the above source. Anyone experiencing these symptoms should seek medical attention.

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If thyroid cancer is suspected, a doctor can diagnose it in several ways. A laryngoscopy is a procedure where the doctor checks the voice box with a mirror or laryngoscope — a thin, tube-like instrument with a light and lens, per NCI.

Signs of thyroid cancer may include lumps or swelling in the neck and trouble breathing. (iStock)

Blood hormone studies – where a blood sample is checked to measure hormone levels – can also reveal indicators of thyroid cancer. Ultrasounds and CAT scans are then used to check for tumors in the body.

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Treatment options

Surgery, radiation, chemotherapy and hormone therapy are the main ways doctors treat thyroid cancer. A new type of therapy, immunotherapy, is being tested in clinical trials.

“Surgery is the primary therapy, followed by regular surveillance and thyroid hormone replacement,” Dr. Marc Siegel, Fox News senior medical analyst, told Fox News Digital.

Bondi, 60, who left her role at the Justice Department in early April, underwent treatment and is recovering, according to a source. (Roberto Schmidt/AFP via Getty Images)

If the thyroid must be completely removed, patients will take hormones to replace the gland’s natural function.

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“Radioactive iodine is added in extensive or more aggressive cases,” Siegel said, but noted that it is “usually not needed.”

The thyroid gland is located in the neck. It makes hormones that are then secreted into the blood, which help the body use energy. (iStock)

Survival rates

The prognosis for thyroid cancer is generally positive and depends heavily on how the cancer responds to treatment, according to NCI.

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Some types are much milder and slower-growing than others. Doctors will also consider the stage of the cancer’s progression.

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The best-case scenario is when a surgeon can completely remove the tumor during surgery. Doctors will also factor in whether this is a brand-new diagnosis or if the cancer has returned after previous treatment.

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