Health
Elton John’s vision loss: How an eye infection can cause blindness
Elton John gives final tour performance to sold out crowd
Elton John completed his “Farewell Yellow Brick Road” tour in Stockholm, Sweden on Saturday, after five years and 330 shows. He addressed the crowd and thanked his fans, saying he will miss them and their support has “humbled” him.
World-renowned singer-songwriter Elton John confirmed he has lost sight in his right eye after suffering from a severe infection.
On the opening night of his musical adaptation of “The Devil Wears Prada” in London, John shared, “I haven’t been able to come to many of the previews because, as you know, I have lost my eyesight.”
“So, it’s hard for me to see it, but I love to hear it and, boy, it sounded good tonight,” he said.
ELTON JOHN HAS ‘LOST MY EYESIGHT’ FOLLOWING SEVERE INFECTION
John first posted to his Instagram account in September that he had been dealing with a “severe eye infection” over the summer that has “unfortunately left me with only limited vision in one eye.”
“Since Sir Elton John did not state what type of eye infection he has, it is unclear whether he has complete blindness in his right eye or if there is still some partial vision,” Dr. Thuy Tran, optometrist and founder of Oculist in New York City, told Fox News Digital.
“It is possible that he may still be able to perceive light and motion, but is unable to discern enough details to read letters or musical notes,” added Tran, who did not treat the singer.
“He may also be experiencing other signs and symptoms, such as thick mucous discharge, pain, irritation, excessive tearing and redness.”
Types of eye infections
The most common types of eye infections are viral conjunctivitis and bacterial conjunctivitis, according to Tran.
“Viral conjunctivitis, caused by adenovirus, are like common colds and typically resolve on their own within a few weeks,” he said.
“When caused by herpes simplex virus, varicella zoster virus (same virus that is responsible for chicken pox and shingles), or cytomegalovirus (seen in immunocompromised individuals i.e. those with HIV/AIDS), more serious complications, such as corneal scarring, retinal damage and vision loss, may result.”
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Bacterial eye infections usually resolve within a week with proper antibiotic treatment, usually eyedrops or ointment, the doctor noted.
“A hyperacute bacterial eye infection, however, can be severe and rapidly progressive,” Tran warned. “If not treated immediately, it can lead to corneal ulcers, scarring and blindness.”
“This condition is most commonly caused by Neisseria gonorrhoeae, a type of bacteria that can be transmitted through sexual contact.”
Bacterial eye infections usually resolve within a week with proper antibiotic treatment, usually eyedrops or ointment. (iStock)
Fungal eye infections are often caused by fungi that are naturally present in our environment, according to Tran.
“Common risk factors include trauma to the eye with plant material, extended contact lens wear and diabetes,” he said.
Fungal infections are usually treated with topical or oral antifungal therapies.
“Rarely, they can lead to a medically-urgent condition known as endophthalmitis, which often requires hospitalization for administration of intravenous medications.”
Potential for permanent damage
Dr. Derek Cunningham, eye doctor and director of Dell Laser Consultants in Austin, Texas, also spoke with Fox News Digital about the dangers of both internal and external infections in the eyes.
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An internal infection can be caused by a virus, said Cunningham, who also did not treat Elton John. If it reaches the retina, or the back of the eye, permanent vision loss can occur.
More commonly, eye infections are the result of external triggers and trauma to the front of the eye, like scratches, chemical splashes or the misuse of contact lenses, he noted.
Elton John speaks onstage during the 38th Annual Rock & Roll Hall Of Fame Induction Ceremony at Barclays Center on Nov. 3, 2023, in New York City. (Theo Wargo/Getty Images for The Rock and Roll Hall of Fame)
These incidents then allow bacteria and other foreign organisms to “colonize in the eye,” Cunningham said.
“Because [the eye] is specifically designed to transmit light, the cellular structure of all the tissues is very precise, and it cannot be altered.”
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“So, any amount of immune response or even bacterial or viral infection is going to cause not only a disruption in the cells, but it could potentially cause scarring – and that is going to reduce vision, very often on a permanent level,” he went on.
While the eye is sensitive and may have a harder time warding off infection since it’s a “compartmentalized” system, Cunningham said, the cornea is also the “fastest-healing tissue in the human body.”
Eye infections are more likely to affect the elderly, according to an expert. (iStock)
But as people age, the body heals more slowly – so someone like John, who is 77 years old, will be at a higher risk of elongated infection compared to those who are younger.
“A little kid can scratch their eye and within hours be completely healed,” Cunningham said. “In an elderly person, [injury] can last for days, and that’s where the chance of infection builds up – every minute that the tissue is still compromised.”
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Some eye complications can be spotted and addressed early on during routine eye exams.
Cunningham recommends paying attention to visual function – and if vision is compromised, symptoms should be evaluated by a doctor.
If vision is compromised, symptoms should be evaluated by a doctor, an expert recommended. (iStock)
“If there is … anything really infectious in the eye, the potential for vision loss is extremely high — and it’s permanent. It very often doesn’t ever come back.”
Representatives for John did not return Fox News Digital’s immediate request for comment.
Fox News Digital’s Elizabeth Stanton contributed to this report.
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Eating too much salt has long been linked to high blood pressure, but new research suggests it could trick the immune system into prematurely aging the blood vessels.
A preclinical study recently published in the Journal of the American Heart Association has identified a biological chain reaction that links a salty diet to cardiovascular decay.
Scientists at the University of South Alabama observed that mice on a high-salt diet experienced rapid deterioration in their blood vessel function.
HIGH SALT INTAKE LINKED TO FASTER MEMORY DECLINE IN ONE GROUP, STUDY FINDS
After just four weeks of high sodium intake, the small arteries responsible for regulating blood flow lost their ability to relax, according to a press release.
The team found that the cells lining these vessels had entered a state of cellular senescence, a form of premature cellular aging in which cells stop dividing and release a mix of inflammatory signals that can damage surrounding tissue.
Excess salt has long been linked to high blood pressure, but a new study goes deeper into its effects on the cardiovascular system. (iStock)
The researchers tried to replicate this damage by exposing blood vessel cells directly to salt in a laboratory dish, but the cells showed no harmful effects.
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This suggests that salt isn’t directly causing damage to the vascular lining but that the real culprit may be the body’s own defense mechanism, the researchers noted.
Excess salt may trigger the immune system to release a molecule called interleukin-16 (IL-16), which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study.
Excess salt may trigger the immune system to release a molecule called interleukin-16, which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study. (iStock)
Once these cells age, they fail to produce nitric oxide, the essential gas that tells arteries to dilate and stay flexible.
To test whether this process could be reversed, the team turned to a class of experimental drugs known as senolytics.
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Using a cancer medication called navitoclax, which selectively clears out aged and dysfunctional cells, the researchers were able to restore nearly normal blood vessel function in the salt-fed mice, the release stated.
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By removing the decaying cells created by the high-salt diet, the drug allowed the remaining healthy tissue to maintain its elasticity and respond correctly to blood flow demands.
Excess salt may trigger the immune system into stopping the cells from dividing, the study suggests. (iStock)
The study did have some limitations. The transition from mouse models to human treatment remains a significant hurdle, the team cautioned.
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Senolytic drugs like navitoclax are still being studied for safety, and the team emphasized that previous trials have shown mixed results regarding their impact on artery plaque.
Additionally, the researchers have not yet confirmed whether the same IL-16 pathway is the primary driver of vascular aging in humans.
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Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests.
The observational study, led by Jorge Nieva, M.D., of the USC Norris Comprehensive Cancer Center at Keck Medicine, was presented this month at the American Association for Cancer Research (AACR) annual meeting in San Diego. It has not yet been peer-reviewed.
Researchers looked at dietary, smoking and demographic data for 187 patients who were diagnosed with lung cancer at age 50 or younger.
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They found that among non-smokers, there was a link between healthier-than-average diets – rich in fruits, vegetables and whole grains – and the chance of lung cancer development.
Young lung cancer patients ate more servings of dark green vegetables, legumes and whole grains compared to the average U.S. adult, the researchers found.
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests. (iStock)
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association.
“Commercially produced (non-organic) fruits, vegetables and whole grains are more likely to be associated with a higher residue of pesticides than dairy, meat and many processed foods,” according to Nieva. He also noted that agricultural workers exposed to pesticides tend to have higher rates of lung cancer.
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“There is a large subset of lung cancer patients whose disease is not caused by smoking,” Nieva told Fox News Digital.
The disease is becoming more common in non-smokers 50 and younger, especially women – despite the fact that smoking rates have been falling for decades, the researcher noted.
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association. (iStock)
“These patients tend to have eaten much healthier diets before their diagnosis than the average American,” he went on. “We need to support research into understanding why Americans – and women in particular – who no longer smoke very much are still having lung cancer,” he said.
DEATHS FROM ONE TYPE OF CANCER ARE SURGING AMONG YOUNGER ADULTS WITHOUT COLLEGE DEGREES
The study did have some limitations, Nieva acknowledged, primarily that it relied on survey data and was limited by the participants’ memories of their food intake.
“Also, the survey participants were self-selected, and this could have biased the findings,” he told Fox News Digital.
“There is a large subset of lung cancer patients whose disease is not caused by smoking.”
The researchers did not test specific foods for pesticides, relying instead on average pesticide levels for certain types of food. Looking ahead, they plan to test patients’ blood and urine samples to directly measure pesticide levels, Nieva said.
Although the study shows only an association and does not prove that pesticides caused lung cancer, Nieva recommends that people wash their produce before eating and choose organic foods whenever possible.
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“This work represents a critical step toward identifying modifiable environmental factors that may contribute to lung cancer in young adults,” said Nieva. “Our hope is that these insights can guide both public health recommendations and future investigation into lung cancer prevention.”
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but is by no means certain,” a doctor said. (AP Photo/Charlie Neibergall)
Dr. Marc Siegel, Fox News senior medical analyst, said the study is “interesting,” but that it “raises far more questions than it answers.”
“It is a small study (around 150) and observational, so no proof,” the doctor, who was not involved in the research, told Fox News Digital.
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“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but it is by no means certain,” Siegel went on. “How much exposure is needed? How much of it gets into food and in which areas? This requires much further study.”
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Kayla Nichols, communications director for Pesticide Action & Agroecology Network, a distributed global network, said the organization agrees with the study’s conclusion that more research should be done on the rise in lung cancer, particularly in individuals eating diets higher in produce and fiber.
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” the researcher told Fox News Digital. (iStock)
“There is a bounty of existing research that already links pesticide exposure to increased risk of multiple types of cancers,” Nichols, who was also not involved in the study, told Fox News Digital. She called for more research on chronic, low-level exposures to pesticides, as well as more effective policies to protect the public from pesticide residues on food.
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The study was supported by the National Institutes of Health and the National Cancer Institute, as well as industry partners including AstraZeneca and Genentech, among others.
Fox News Digital reached out to several pesticide companies and trade groups for comment.
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