Health
Doctor and cancer survivor gears up to run 7 marathons on 7 continents in 7 days
A Wisconsin doctor is gearing up for the feat of a lifetime in order to spread awareness about the most pervasive cancer impacting young men.
Dr. T. Clark Gamblin, a surgeon in Milwaukee, spoke with Fox News Digital about his upcoming participation in the World Marathon Challenge. The competition involves running seven marathons on seven continents – seven days in a row.
The first marathon will take place in Antarctica on Jan. 31, 2025. From there, Gamblin and other participants will travel to Cape Town, South Africa; Perth, Australia; and Dubai, UAE.
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From there, Gamblin will jet to Madrid, Spain, and Fortaleza, Brazil, before running a final race in Miami. He and his fellow marathon runners will have logged 183 miles over the course of a week.
Dr. T. Clark Gamblin, a cancer surgeon who battled testicular cancer, is running in the World Marathon Challenge, which involves running seven marathons on seven continents – seven days in a row. (Jan Gamblin, Ph.D.)
The fast-paced nature of the competition means that it won’t exactly be a relaxing vacation for the participants.
“Over the course of the seven days, we’ll spend about 60 hours on the plane,” Gamblin said. “So it’s running, and it’s plane, and it’s running, and then it’s plane.”
“If you’re prepared and you train correctly, it’s not some Herculean feat.”
While it may seem physically impossible for a human to run seven marathons in seven consecutive days, the World Marathon Challenge has taken runners across the world for nearly a decade. Gamblin began training for the race a year ago.
“It’s a physical challenge, there’s no doubt about it, but there are much more physically demanding things that people have done,” he said. “If you’re prepared and you train correctly, it’s not some Herculean feat.”
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Gamblin has a whole team behind him. The World Marathon Challenge organization handles the logistics of all participants’ flights and hotels. A cancer surgeon, Gamblin also enlisted the help of a dietitian at his hospital to help him meet his protein and fluid goals.
He also has a physical trainer to help with injury prevention — but the person who has helped Gamblin the most, he said, is his wife.
Dr. T. Clark Gamblin spoke to Fox News Digital about his participation in the World Marathon Challenge. (Fox News Digital / Jan Gamblin, Ph.D.)
“She’s like my No. 1 cheerleader,” Gamblin said. “She’s not a big runner, but she’s a huge part of helping me get ready for this and preparing me for it.”
“But then right behind her would be my running coach, a dietitian and a physical therapist. So it does take a team to get ready for something like this.”
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Gamblin, who specializes in liver and bile duct cancer, became interested in running marathons as a medical school student. During the World Marathon Challenge, he will be running for the Testicular Cancer Awareness Foundation.
The cause is near to his heart, as Gamblin is a cancer survivor himself – he was diagnosed with testicular cancer in 2018 after noticing a lump.
Gamblin has been working with a dietitian and a physical trainer to prepare for the seven-day marathon challenge. (Jan Gamblin, Ph.D.)
“I thought it was probably nothing, but I was really diligent about it and checked it out very quickly and discovered it was testicular cancer,” he explained. “And testicular cancer is the No. 1 cancer that affects males aged 15 to 45.”
One out of every 250 men will develop testicular cancer in their lifetime, according to the Testicular Cancer Awareness Foundation.
“I went from being a cancer surgeon and giving all this advice, to having to take the advice I had been giving and apply it in my own life,” Gamblin noted.
“The most intriguing one is the Antarctica race … it’s going to be such a unique environment and climate to run in.”
After going through chemotherapy and two operations, he has now been cancer-free for four years.
Gamblin’s desire to spread awareness has fueled the long and arduous training he has gone through to prepare for the 168-hour-long feat.
Despite the challenges, he said he looks forward to the simple pleasures of the race, such as getting to know his fellow runners.
Gamblin will run a marathon on every continent, including Antarctica, starting in January. (Jan Gamblin, Ph.D.)
“It’ll be such a unique group of people, too,” he said. “I’m prepared to make some lifetime friendships and hear other people’s stories.”
Gamblin is documenting his marathon journey through his Instagram account, @tclarkgamblin. He’s most excited about running through Antarctica.
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“So few people have run marathons there,” he said. “It’s going to be such a unique environment and climate to run in.”
In Miami, Gamblin will get to see his family at the finish line.
Gamblin said that he hopes his story encourages others to achieve their potential. (Jan Gamblin, Ph.D)
“I think that far too often, we don’t set our goals high enough in life,” the doctor said. “We don’t risk enough …This is a risk, it is a reach for me.”
The doctor said he aims to inspire other people to also set their sights higher than they normally would.
“Your body will in many cases do what the mind tells it to do,” Gamblin added.
“And so I think we can challenge ourselves and push ourselves far beyond … the limits that we set.”
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Eating too much salt has long been linked to high blood pressure, but new research suggests it could trick the immune system into prematurely aging the blood vessels.
A preclinical study recently published in the Journal of the American Heart Association has identified a biological chain reaction that links a salty diet to cardiovascular decay.
Scientists at the University of South Alabama observed that mice on a high-salt diet experienced rapid deterioration in their blood vessel function.
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After just four weeks of high sodium intake, the small arteries responsible for regulating blood flow lost their ability to relax, according to a press release.
The team found that the cells lining these vessels had entered a state of cellular senescence, a form of premature cellular aging in which cells stop dividing and release a mix of inflammatory signals that can damage surrounding tissue.
Excess salt has long been linked to high blood pressure, but a new study goes deeper into its effects on the cardiovascular system. (iStock)
The researchers tried to replicate this damage by exposing blood vessel cells directly to salt in a laboratory dish, but the cells showed no harmful effects.
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This suggests that salt isn’t directly causing damage to the vascular lining but that the real culprit may be the body’s own defense mechanism, the researchers noted.
Excess salt may trigger the immune system to release a molecule called interleukin-16 (IL-16), which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study.
Excess salt may trigger the immune system to release a molecule called interleukin-16, which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study. (iStock)
Once these cells age, they fail to produce nitric oxide, the essential gas that tells arteries to dilate and stay flexible.
To test whether this process could be reversed, the team turned to a class of experimental drugs known as senolytics.
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Using a cancer medication called navitoclax, which selectively clears out aged and dysfunctional cells, the researchers were able to restore nearly normal blood vessel function in the salt-fed mice, the release stated.
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By removing the decaying cells created by the high-salt diet, the drug allowed the remaining healthy tissue to maintain its elasticity and respond correctly to blood flow demands.
Excess salt may trigger the immune system into stopping the cells from dividing, the study suggests. (iStock)
The study did have some limitations. The transition from mouse models to human treatment remains a significant hurdle, the team cautioned.
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Senolytic drugs like navitoclax are still being studied for safety, and the team emphasized that previous trials have shown mixed results regarding their impact on artery plaque.
Additionally, the researchers have not yet confirmed whether the same IL-16 pathway is the primary driver of vascular aging in humans.
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Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests.
The observational study, led by Jorge Nieva, M.D., of the USC Norris Comprehensive Cancer Center at Keck Medicine, was presented this month at the American Association for Cancer Research (AACR) annual meeting in San Diego. It has not yet been peer-reviewed.
Researchers looked at dietary, smoking and demographic data for 187 patients who were diagnosed with lung cancer at age 50 or younger.
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They found that among non-smokers, there was a link between healthier-than-average diets – rich in fruits, vegetables and whole grains – and the chance of lung cancer development.
Young lung cancer patients ate more servings of dark green vegetables, legumes and whole grains compared to the average U.S. adult, the researchers found.
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests. (iStock)
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association.
“Commercially produced (non-organic) fruits, vegetables and whole grains are more likely to be associated with a higher residue of pesticides than dairy, meat and many processed foods,” according to Nieva. He also noted that agricultural workers exposed to pesticides tend to have higher rates of lung cancer.
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“There is a large subset of lung cancer patients whose disease is not caused by smoking,” Nieva told Fox News Digital.
The disease is becoming more common in non-smokers 50 and younger, especially women – despite the fact that smoking rates have been falling for decades, the researcher noted.
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association. (iStock)
“These patients tend to have eaten much healthier diets before their diagnosis than the average American,” he went on. “We need to support research into understanding why Americans – and women in particular – who no longer smoke very much are still having lung cancer,” he said.
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The study did have some limitations, Nieva acknowledged, primarily that it relied on survey data and was limited by the participants’ memories of their food intake.
“Also, the survey participants were self-selected, and this could have biased the findings,” he told Fox News Digital.
“There is a large subset of lung cancer patients whose disease is not caused by smoking.”
The researchers did not test specific foods for pesticides, relying instead on average pesticide levels for certain types of food. Looking ahead, they plan to test patients’ blood and urine samples to directly measure pesticide levels, Nieva said.
Although the study shows only an association and does not prove that pesticides caused lung cancer, Nieva recommends that people wash their produce before eating and choose organic foods whenever possible.
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“This work represents a critical step toward identifying modifiable environmental factors that may contribute to lung cancer in young adults,” said Nieva. “Our hope is that these insights can guide both public health recommendations and future investigation into lung cancer prevention.”
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but is by no means certain,” a doctor said. (AP Photo/Charlie Neibergall)
Dr. Marc Siegel, Fox News senior medical analyst, said the study is “interesting,” but that it “raises far more questions than it answers.”
“It is a small study (around 150) and observational, so no proof,” the doctor, who was not involved in the research, told Fox News Digital.
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“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but it is by no means certain,” Siegel went on. “How much exposure is needed? How much of it gets into food and in which areas? This requires much further study.”
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Kayla Nichols, communications director for Pesticide Action & Agroecology Network, a distributed global network, said the organization agrees with the study’s conclusion that more research should be done on the rise in lung cancer, particularly in individuals eating diets higher in produce and fiber.
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” the researcher told Fox News Digital. (iStock)
“There is a bounty of existing research that already links pesticide exposure to increased risk of multiple types of cancers,” Nichols, who was also not involved in the study, told Fox News Digital. She called for more research on chronic, low-level exposures to pesticides, as well as more effective policies to protect the public from pesticide residues on food.
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The study was supported by the National Institutes of Health and the National Cancer Institute, as well as industry partners including AstraZeneca and Genentech, among others.
Fox News Digital reached out to several pesticide companies and trade groups for comment.
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