Health
‘Disease X’ has killed dozens in the Congo — here’s what to know about the mystery illness
An outbreak of a mystery illness dubbed “Disease X” has killed dozens in the Democratic Republic of Congo (DRC), health officials say.
Up to 143 people have died from the infectious disease, the country’s deputy provincial governor, Rémy Saki, told the Associated Press on Tuesday.
The deaths occurred in the Panzi health zone of Kwango province between Nov. 10 and Nov. 25, AP reported this week.
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Primary symptoms include fever, headache, cough and difficulty breathing.
Most of those affected are children younger than 5 years old.
An outbreak of a mysterious illness dubbed “Disease X” has killed dozens in the Democratic Republic of Congo (DRC), health officials say. (iStock)
“At the Emergency Operation Center for Public Health and at the INSP [National Institute of Public Health] — which is in maximum alert mode — we’ve already positioned central-level teams who will leave within 24 hours to join the [local] health zone,” said Dr. Dieudonné Mwamba, the director general of INSP, speaking in French at a press briefing on Thursday.
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The DRC’s provincial health minister, Apollinaire Yumba, urged residents to be cautious and to avoid contact with dead bodies to prevent infection, AP reported.
The country is also requesting medical supplies.
“There is a lack of medicines and medical supplies, since the disease is not yet known.”
The first cases of Disease X were reported on Oct. 24, but health authorities were not notified until Dec. 1, according to reports.
Jean Kaseya, director of the Africa Centres for Disease Control and Prevention, spoke at a press conference on Thursday.
“We have a delay of almost five to six weeks, and in five to six weeks, so many things can happen,” Kaseya said.
“Ongoing testing will help us to understand what is the issue.”
Up to 143 people have died from the infectious disease, the country’s deputy provincial governor, Rémy Saki, told the Associated Press on Tuesday. (iStock)
Lucien Lufutu, president of the civil society consultation framework of Kwango province, who is in Panzi, told the AP that the local hospital is not equipped to treat the influx of ill patients.
“There is a lack of medicines and medical supplies, since the disease is not yet known, most of the population is treated by traditional practitioners,” he said.
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When contacted by Fox News Digital, the U.S. Centers for Disease Control and Prevention (CDC) said it is aware of reports of an illness in southwest DRC.
“U.S. government staff, including those from U.S. CDC’s country office in Kinshasa, are in contact with DRC’s Ministry of Health and stand ready to provide additional support if needed,” a spokesperson said.
The first cases of Disease X were reported on Oct. 24, but health authorities were not notified until Dec. 1, according to reports. (iStock)
The Congo is already grappling with an ongoing outbreak of mpox, a viral disease caused by an orthopoxvirus. A global emergency was declared in August.
In recent weeks, health officials have reported between 200 and 300 confirmed mpox cases weekly, according to data from the World Health Organization (WHO).
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Fox News Digital also reached out to the Africa CDC and WHO requesting additional comment.
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Eating too much salt has long been linked to high blood pressure, but new research suggests it could trick the immune system into prematurely aging the blood vessels.
A preclinical study recently published in the Journal of the American Heart Association has identified a biological chain reaction that links a salty diet to cardiovascular decay.
Scientists at the University of South Alabama observed that mice on a high-salt diet experienced rapid deterioration in their blood vessel function.
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After just four weeks of high sodium intake, the small arteries responsible for regulating blood flow lost their ability to relax, according to a press release.
The team found that the cells lining these vessels had entered a state of cellular senescence, a form of premature cellular aging in which cells stop dividing and release a mix of inflammatory signals that can damage surrounding tissue.
Excess salt has long been linked to high blood pressure, but a new study goes deeper into its effects on the cardiovascular system. (iStock)
The researchers tried to replicate this damage by exposing blood vessel cells directly to salt in a laboratory dish, but the cells showed no harmful effects.
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This suggests that salt isn’t directly causing damage to the vascular lining but that the real culprit may be the body’s own defense mechanism, the researchers noted.
Excess salt may trigger the immune system to release a molecule called interleukin-16 (IL-16), which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study.
Excess salt may trigger the immune system to release a molecule called interleukin-16, which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study. (iStock)
Once these cells age, they fail to produce nitric oxide, the essential gas that tells arteries to dilate and stay flexible.
To test whether this process could be reversed, the team turned to a class of experimental drugs known as senolytics.
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Using a cancer medication called navitoclax, which selectively clears out aged and dysfunctional cells, the researchers were able to restore nearly normal blood vessel function in the salt-fed mice, the release stated.
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By removing the decaying cells created by the high-salt diet, the drug allowed the remaining healthy tissue to maintain its elasticity and respond correctly to blood flow demands.
Excess salt may trigger the immune system into stopping the cells from dividing, the study suggests. (iStock)
The study did have some limitations. The transition from mouse models to human treatment remains a significant hurdle, the team cautioned.
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Senolytic drugs like navitoclax are still being studied for safety, and the team emphasized that previous trials have shown mixed results regarding their impact on artery plaque.
Additionally, the researchers have not yet confirmed whether the same IL-16 pathway is the primary driver of vascular aging in humans.
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Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests.
The observational study, led by Jorge Nieva, M.D., of the USC Norris Comprehensive Cancer Center at Keck Medicine, was presented this month at the American Association for Cancer Research (AACR) annual meeting in San Diego. It has not yet been peer-reviewed.
Researchers looked at dietary, smoking and demographic data for 187 patients who were diagnosed with lung cancer at age 50 or younger.
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They found that among non-smokers, there was a link between healthier-than-average diets – rich in fruits, vegetables and whole grains – and the chance of lung cancer development.
Young lung cancer patients ate more servings of dark green vegetables, legumes and whole grains compared to the average U.S. adult, the researchers found.
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests. (iStock)
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association.
“Commercially produced (non-organic) fruits, vegetables and whole grains are more likely to be associated with a higher residue of pesticides than dairy, meat and many processed foods,” according to Nieva. He also noted that agricultural workers exposed to pesticides tend to have higher rates of lung cancer.
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“There is a large subset of lung cancer patients whose disease is not caused by smoking,” Nieva told Fox News Digital.
The disease is becoming more common in non-smokers 50 and younger, especially women – despite the fact that smoking rates have been falling for decades, the researcher noted.
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association. (iStock)
“These patients tend to have eaten much healthier diets before their diagnosis than the average American,” he went on. “We need to support research into understanding why Americans – and women in particular – who no longer smoke very much are still having lung cancer,” he said.
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The study did have some limitations, Nieva acknowledged, primarily that it relied on survey data and was limited by the participants’ memories of their food intake.
“Also, the survey participants were self-selected, and this could have biased the findings,” he told Fox News Digital.
“There is a large subset of lung cancer patients whose disease is not caused by smoking.”
The researchers did not test specific foods for pesticides, relying instead on average pesticide levels for certain types of food. Looking ahead, they plan to test patients’ blood and urine samples to directly measure pesticide levels, Nieva said.
Although the study shows only an association and does not prove that pesticides caused lung cancer, Nieva recommends that people wash their produce before eating and choose organic foods whenever possible.
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“This work represents a critical step toward identifying modifiable environmental factors that may contribute to lung cancer in young adults,” said Nieva. “Our hope is that these insights can guide both public health recommendations and future investigation into lung cancer prevention.”
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but is by no means certain,” a doctor said. (AP Photo/Charlie Neibergall)
Dr. Marc Siegel, Fox News senior medical analyst, said the study is “interesting,” but that it “raises far more questions than it answers.”
“It is a small study (around 150) and observational, so no proof,” the doctor, who was not involved in the research, told Fox News Digital.
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“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but it is by no means certain,” Siegel went on. “How much exposure is needed? How much of it gets into food and in which areas? This requires much further study.”
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Kayla Nichols, communications director for Pesticide Action & Agroecology Network, a distributed global network, said the organization agrees with the study’s conclusion that more research should be done on the rise in lung cancer, particularly in individuals eating diets higher in produce and fiber.
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” the researcher told Fox News Digital. (iStock)
“There is a bounty of existing research that already links pesticide exposure to increased risk of multiple types of cancers,” Nichols, who was also not involved in the study, told Fox News Digital. She called for more research on chronic, low-level exposures to pesticides, as well as more effective policies to protect the public from pesticide residues on food.
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The study was supported by the National Institutes of Health and the National Cancer Institute, as well as industry partners including AstraZeneca and Genentech, among others.
Fox News Digital reached out to several pesticide companies and trade groups for comment.
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