Health
Dairy Workers May Have Passed Bird Flu to Pet Cats, CDC Study Suggests
Two dairy workers in Michigan may have transmitted bird flu to their pet cats last May, suggests a new study published on Thursday by the Centers for Disease Control and Prevention.
In one household, infected cats may also have passed the virus to other people in the home, but limited evidence makes it difficult to ascertain the possibility.
The results are from a study that was scheduled to be published in January but was delayed by the Trump administration’s pause on communications from the C.D.C.
A single data table from the new report briefly appeared online two weeks ago in a paper on the wildfires in California, then quickly disappeared. That odd incident prompted calls from public health experts for the study’s release.
The new paper still leaves major questions unanswered, including how the cats first became infected and whether farmworkers spread the virus to the cats and to other people in the household, experts said.
“I don’t think we can say for sure if this is human-to-cat or cat-to-human or cat-from-something-else,” said Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health.
Officials in Michigan began investigating two households last May when exclusively indoor cats showed respiratory and neurological symptoms and, after death, tested positive for the virus, called H5N1. The officials interviewed the cats’ owners and household members and offered to test them for the virus.
The owners of both cats were dairy workers. The first farmworker did not work with cows directly, and the farm was not known to have infected herds. But the worker reported that many of the barn cats on the farm’s premises recently died. The worker also reported having experienced vomiting and diarrhea before the first household cat became ill.
The second farmworker reported being splashed in the face and eyes with milk and experiencing eye irritation. Both workers declined to be tested.
“This study provides yet more concerning evidence that farmworkers with high-risk exposures may refuse testing,” Dr. Nuzzo said.
“In order to protect people and stay ahead of this virus, we need to remove disincentives for patients to get tested,” she added. “People should not fear that testing positive will cause financial distress or other personal harms.”
In the household of the first farmworker, the first cat to become ill showed decreased appetite, lack of grooming, abnormal gait and lethargy, and quickly deteriorated. She was euthanized on the fourth day of illness.
A second cat in the household developed watery eye discharge, rapid breathing and decreased appetite four days after the first cat became ill. This cat recovered and was not tested for the virus. A third cat had no symptoms and tested negative for the virus 11 days after the first cat became ill.
Neither the cats nor the humans in the household drank unpasteurized milk. How the cats might have become infected is unclear, but experts said that the farmworkers were likely to have become infected with H5N1 at their workplace and to have brought the virus home to their cats.
“If you love your cat, you probably give it head kisses if it lets you,” said Kristen K. Coleman, an infectious disease researcher at the University of Maryland.
Three people in the household — an adult and two adolescents — tested negative for H5N1. Six days after the first cat became sick, one of the adolescents became ill with a cough, sore throat and body aches, and the other reported a cough that was attributed to allergies.
But because the adolescents were tested late — 11 days after the first cat became sick — it was not impossible that they became infected with H5N1 that they picked up from the cats, Dr. Coleman said.
Later in May, a pet cat in the second household developed severe neurological symptoms, including anorexia and minimal movement, and died within a day; the cat tested positive for bird flu after its death.
The cat’s owner transported unpasteurized milk, including from farms with known bird flu outbreaks. According to the study, the owner “did not wear personal protective equipment (PPE) while handling raw milk; reported frequent milk splash exposures to the face, eyes and clothing; and did not remove work clothing before entering the home when returning from work.”
The cat that became ill was known to “roll in the owner’s work clothes,” the study noted.
Virus in raw milk splattered on those clothes may be the source of infection in the cat, said Dr. Keith Poulsen, the director of the Wisconsin Veterinary Diagnostic Laboratory.
“At this point, I think the higher risk is their exposure from raw dairy products,” he said. “There’s so much virus in the milk.”
Of 24 veterinary staff members who were potentially exposed to the infected cats, seven reported symptoms such as nasal congestion and headache. Only five agreed to testing; all were negative.
Dr. Coleman recommended that veterinarians remain alert to the possibility of bird flu infections when they see sick cats. “Pet owners should not have to rely on postmortem sampling to get a diagnosis,” she said.
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Eating too much salt has long been linked to high blood pressure, but new research suggests it could trick the immune system into prematurely aging the blood vessels.
A preclinical study recently published in the Journal of the American Heart Association has identified a biological chain reaction that links a salty diet to cardiovascular decay.
Scientists at the University of South Alabama observed that mice on a high-salt diet experienced rapid deterioration in their blood vessel function.
HIGH SALT INTAKE LINKED TO FASTER MEMORY DECLINE IN ONE GROUP, STUDY FINDS
After just four weeks of high sodium intake, the small arteries responsible for regulating blood flow lost their ability to relax, according to a press release.
The team found that the cells lining these vessels had entered a state of cellular senescence, a form of premature cellular aging in which cells stop dividing and release a mix of inflammatory signals that can damage surrounding tissue.
Excess salt has long been linked to high blood pressure, but a new study goes deeper into its effects on the cardiovascular system. (iStock)
The researchers tried to replicate this damage by exposing blood vessel cells directly to salt in a laboratory dish, but the cells showed no harmful effects.
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This suggests that salt isn’t directly causing damage to the vascular lining but that the real culprit may be the body’s own defense mechanism, the researchers noted.
Excess salt may trigger the immune system to release a molecule called interleukin-16 (IL-16), which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study.
Excess salt may trigger the immune system to release a molecule called interleukin-16, which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study. (iStock)
Once these cells age, they fail to produce nitric oxide, the essential gas that tells arteries to dilate and stay flexible.
To test whether this process could be reversed, the team turned to a class of experimental drugs known as senolytics.
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Using a cancer medication called navitoclax, which selectively clears out aged and dysfunctional cells, the researchers were able to restore nearly normal blood vessel function in the salt-fed mice, the release stated.
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By removing the decaying cells created by the high-salt diet, the drug allowed the remaining healthy tissue to maintain its elasticity and respond correctly to blood flow demands.
Excess salt may trigger the immune system into stopping the cells from dividing, the study suggests. (iStock)
The study did have some limitations. The transition from mouse models to human treatment remains a significant hurdle, the team cautioned.
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Senolytic drugs like navitoclax are still being studied for safety, and the team emphasized that previous trials have shown mixed results regarding their impact on artery plaque.
Additionally, the researchers have not yet confirmed whether the same IL-16 pathway is the primary driver of vascular aging in humans.
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Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests.
The observational study, led by Jorge Nieva, M.D., of the USC Norris Comprehensive Cancer Center at Keck Medicine, was presented this month at the American Association for Cancer Research (AACR) annual meeting in San Diego. It has not yet been peer-reviewed.
Researchers looked at dietary, smoking and demographic data for 187 patients who were diagnosed with lung cancer at age 50 or younger.
PANCREATIC CANCER PATIENT SURVIVAL DOUBLED WITH HIGH DOSE OF COMMON VITAMIN, STUDY FINDS
They found that among non-smokers, there was a link between healthier-than-average diets – rich in fruits, vegetables and whole grains – and the chance of lung cancer development.
Young lung cancer patients ate more servings of dark green vegetables, legumes and whole grains compared to the average U.S. adult, the researchers found.
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests. (iStock)
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association.
“Commercially produced (non-organic) fruits, vegetables and whole grains are more likely to be associated with a higher residue of pesticides than dairy, meat and many processed foods,” according to Nieva. He also noted that agricultural workers exposed to pesticides tend to have higher rates of lung cancer.
HIDDEN VIRUS INSIDE GUT BACTERIA LINKED TO DOUBLED COLORECTAL CANCER RISK, STUDY FINDS
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” Nieva told Fox News Digital.
The disease is becoming more common in non-smokers 50 and younger, especially women – despite the fact that smoking rates have been falling for decades, the researcher noted.
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association. (iStock)
“These patients tend to have eaten much healthier diets before their diagnosis than the average American,” he went on. “We need to support research into understanding why Americans – and women in particular – who no longer smoke very much are still having lung cancer,” he said.
DEATHS FROM ONE TYPE OF CANCER ARE SURGING AMONG YOUNGER ADULTS WITHOUT COLLEGE DEGREES
The study did have some limitations, Nieva acknowledged, primarily that it relied on survey data and was limited by the participants’ memories of their food intake.
“Also, the survey participants were self-selected, and this could have biased the findings,” he told Fox News Digital.
“There is a large subset of lung cancer patients whose disease is not caused by smoking.”
The researchers did not test specific foods for pesticides, relying instead on average pesticide levels for certain types of food. Looking ahead, they plan to test patients’ blood and urine samples to directly measure pesticide levels, Nieva said.
Although the study shows only an association and does not prove that pesticides caused lung cancer, Nieva recommends that people wash their produce before eating and choose organic foods whenever possible.
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“This work represents a critical step toward identifying modifiable environmental factors that may contribute to lung cancer in young adults,” said Nieva. “Our hope is that these insights can guide both public health recommendations and future investigation into lung cancer prevention.”
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but is by no means certain,” a doctor said. (AP Photo/Charlie Neibergall)
Dr. Marc Siegel, Fox News senior medical analyst, said the study is “interesting,” but that it “raises far more questions than it answers.”
“It is a small study (around 150) and observational, so no proof,” the doctor, who was not involved in the research, told Fox News Digital.
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“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but it is by no means certain,” Siegel went on. “How much exposure is needed? How much of it gets into food and in which areas? This requires much further study.”
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Kayla Nichols, communications director for Pesticide Action & Agroecology Network, a distributed global network, said the organization agrees with the study’s conclusion that more research should be done on the rise in lung cancer, particularly in individuals eating diets higher in produce and fiber.
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” the researcher told Fox News Digital. (iStock)
“There is a bounty of existing research that already links pesticide exposure to increased risk of multiple types of cancers,” Nichols, who was also not involved in the study, told Fox News Digital. She called for more research on chronic, low-level exposures to pesticides, as well as more effective policies to protect the public from pesticide residues on food.
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The study was supported by the National Institutes of Health and the National Cancer Institute, as well as industry partners including AstraZeneca and Genentech, among others.
Fox News Digital reached out to several pesticide companies and trade groups for comment.
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