Connect with us

Health

Common respiratory bacteria detected in eyes of Alzheimer’s patients

Published

on

Common respiratory bacteria detected in eyes of Alzheimer’s patients

NEWYou can now listen to Fox News articles!

A bacterium prevalent in sinus infections and pneumonia may aggravate Alzheimer’s disease, according to a recent study published in Nature Communications. 

The bacterium, Chlamydia pneumoniae, was found in the eyes of deceased patients with Alzheimer’s disease, according to researchers from Cedars-Sinai’s Health Sciences University in California.

“The retina is directly connected with the brain. It’s a developmental extension of the brain,” lead researcher Maya Koronyo-Hamaoui, PhD, professor of neurosurgery, neurology and biomedical sciences at Cedars-Sinai Health Sciences University, told Fox News Digital.

COMMON HOUSEHOLD PLANT COULD HOLD KEY TO FIGHTING ALZHEIMER’S DISEASE

Advertisement

Eye-brain link

The study showed that Chlamydia pneumoniae could reach the retinal tissue that lines the back of the eye and linger for several years, creating an inflammatory response potentially linked to the death of nerve cells. This could contribute to cognitive decline and could worsen Alzheimer’s disease symptoms. 

A bacterium prevalent in sinus infections and pneumonia may aggravate Alzheimer’s disease, according to a recent study published in Nature Communications.  (iStock)

The findings point to potential therapies for Alzheimer’s disease that would target inflammation and provide antibiotic treatment in the early stages of infection, according to Koronyo-Hamaoui.

“One hope of this study is that when people do present with some [symptoms of] pneumonia or atypical pneumonia or some respiratory infection, doctors should consider testing specifically for Chlamydia pneumoniae, and then give them the specific antibiotic,” the researcher said.

BRAIN TRAINING SESSIONS FOUND TO REDUCE DEMENTIA RISK IN DECADES-LONG STUDY

Advertisement

The infection can be identified through laboratory testing, including PCR (polymerase chain reaction), blood tests, or cultures that allow live organisms to grow for analysis.

Inside the study

The researchers examined retinal tissue samples from over 100 deceased individuals who fell into three groups: those who had Alzheimer’s disease, those who had some cognitive deficit or those who did not have the disease. 

“The retina is directly connected with the brain. It’s a developmental extension of the brain,” the lead researcher said. (iStock)

They analyzed proteins, conducted genetic testing and used advanced imaging techniques on the samples. Those with Alzheimer’s disease had higher levels of the bacterium in their brains and retinal tissue compared to those who had normal cognition, the release stated.

Genetic risk

Higher levels of chlamydia pneumonia were found in those who carried the gene variant APOE4, which is an associated risk factor for Alzheimer’s disease, Koronyo-Hamaoui added. The bacterium was also associated with more severe cognition decline.  

Advertisement

Those with Alzheimer’s disease had higher levels of the bacterium in their brains and retinal tissue compared to those who had normal cognition. (iStock)

The Cedars-Sinai team also looked at human neurons and lab mice with Alzheimer’s disease, finding that Chlamydia pneumoniae was linked to increased inflammation, nerve cell death and cognitive decline, further suggesting that it may play a role in accelerating the disease. 

The infection also prompted production of amyloid-beta, which is a protein known to accumulate in the brains of those with Alzheimer’s, Koronyo-Hamaoui said.

While the study points toward using the retina as a way to diagnose and monitor the disease, the researcher acknowledged that more research is needed to confirm these findings.

Advertisement

Experts urge caution

Dr. Aaron Glatt, chief of infectious diseases at Mount Sinai South Nassau on Long Island, New York, was not involved with the study but called the findings “interesting.” 

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Glatt, who is also a spokesperson for the Infectious Diseases Society of America, emphasized that the findings only show an association and not causation, and that much more clinical research is needed.

“It does not mean infections cause Alzheimer’s or that people should worry about past respiratory illnesses.”

“Chlamydia pneumoniae is a very common respiratory pathogen that many people are exposed to throughout their lives,” he told Fox News Digital. “While the study identifies a link between this bacterium and neurodegeneration, a standard sinus infection does not mean a patient will develop Alzheimer’s.”

Advertisement

The key takeaway, according to Glatt, is that the study opens new doors for potential diagnostics and treatments, but is “not a reason for immediate alarm regarding common infections.”

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

Dr. Sharon Fekrat, MD, a clinical spokesperson for the American Academy of Ophthalmology and a retina specialist at the Duke University School of Medicine in North Carolina, agreed that the findings could help researchers better understand how inflammation may drive disease progression and “could lead to new ways to detect or treat Alzheimer’s in the future.”

The infection also prompted production of amyloid-beta, which is a protein known to accumulate in the brains of those with Alzheimer’s. (iStock)

“This is early research suggesting that infection-related inflammation may worsen Alzheimer’s disease in people who are already vulnerable,” Fekrat, who also did not work on the study, told Fox News Digital. “It does not mean infections cause Alzheimer’s or that people should worry about past respiratory illnesses.”

Advertisement

What’s next

While some teams are developing and testing retinal imaging tools in living patients, those methods are not yet part of routine clinical screenings or diagnosis, Fekrat noted.

CLICK HERE FOR MORE HEALTH STORIES

For now, the best proven steps include following brain-healthy habits, such as managing cardiovascular risk factors, staying mentally and socially engaged, and seeking medical care for any cognitive symptoms, the expert added.

Health

The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s

Published

on

The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s


Advertisement




Natural Ozempic Alternatives That Boost GLP-1 for Weight Loss | Woman’s World




















Advertisement





Advertisement


Use left and right arrow keys to navigate between menu items.


Use escape to exit the menu.

Advertisement

Continue Reading

Health

Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

Published

on

Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

NEWYou can now listen to Fox News articles!

In a dramatic turn of events that’s captured the attention of animal lovers worldwide, Punch — the young macaque at a zoo in Japan famous for his inseparable bond with a stuffed orangutan toy — has reached a major milestone in his journey toward social integration.

On Thursday, visitors and staff at the Ichikawa Zoological and Botanical Garden witnessed a breakthrough: Punch was seen cuddling with and hitching a ride on the back of a fellow macaque.

Punch’s story began with hardship. He was abandoned by his mother shortly after his birth in July 2025 — and to ensure his survival, zookeepers stepped in to hand-rear the primate.

On Jan. 19, 2026, the zoo officially began the process of reintegrating Punch into the “monkey mountain” enclosure.

Advertisement

The transition was initially fraught with tension. 

Punch’s story began with hardship when he was abandoned by his mother shortly after he was born. To help him, zookeepers gave him a stuffed toy that he began dragging around everywhere he went.  (David Mareuil/Anadolu via Getty Images)

As a hand-reared infant, Punch was bullied and ignored by the established group of monkeys.

He was often seen huddled alone with his orange plush companion while the rest of the troop interacted.

BABY MONKEY CARRIES FAITHFUL STUFFED COMPANION EVERYWHERE HE GOES, DRAWING CROWDS AT ZOO

Advertisement

In an official statement released Feb. 27, the Ichikawa Zoological and Botanical Garden detailed the meticulous care behind this process.

Previous viral videos showed Punch bullied by the rest of the troop, running to his plushy toy for comfort. (David Mareuil/Anadolu via Getty Images)

“From an animal welfare perspective, our primary goal is to reintegrate Punch with the troop,” the zoo said. 

CLICK HERE FOR MORE LIFESTYLE STORIES

The strategy involved nursing Punch within the enclosure, so the troop could recognize him as one of their own, and pairing him with a gentle young female macaque prior to his full release to build his confidence.

Advertisement

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

The latest footage, captured by X user @tate_gf, suggested the zoo’s patience is paying off. 

The video shows Punch seeking physical contact not from his toy, but from another monkey — eventually climbing onto its back for a vital social behavior for young macaques: the “piggyback ride.”

The zoo’s strategy appears to be paying off: Punch, shown at far left, was recently seen riding on the back of a fellow macaque. (David Mareuil/Anadolu via Getty Images)

While Punch still carries his stuffed toy for comfort during moments of perceived danger, the zoo remains optimistic about his progress. 

Advertisement

The organization cited the successful 2009 case of Otome, another hand-reared macaque who eventually outgrew her stuffed toy, successfully integrated — and went on to raise four offspring of her own.

The zoo has had crowds coming to see Punch, with hundreds of people lining up to get inside to see the young star, according to reports. 

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

“I’m hoping Punch has a good life like everybody else does, and think he’s a cute little guy,” one person commented online. 

Advertisement

“Such a precious baby,” another person wrote. 

Related Article

Orphaned baby monkey finds comfort in stuffed animal after being abandoned by mother at birth
Continue Reading

Health

ChatGPT could miss your serious medical emergency, new study suggests

Published

on

ChatGPT could miss your serious medical emergency, new study suggests

NEWYou can now listen to Fox News articles!

This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).

Artificial intelligence has been touted as a boon to healthcare, but a new study has revealed its potential shortcomings when it comes to giving medical advice.

In January, OpenAI launched ChatGPT Health, the medical-focused version of the popular chatbot tool. 

The company introduced the tool as “a dedicated experience that securely brings your health information and ChatGPT’s intelligence together, to help you feel more informed, prepared and confident navigating your health.”

Advertisement

But researchers at the Icahn School of Medicine at Mount Sinai have found that the tool failed to recommend emergency care for a “significant number” of serious medical cases.

The study, published in the journal Nature Medicine on Feb. 23, aimed to explore how ChatGPT Health — which is reported to have about 40 million users daily — handles situations where people are asking whether to seek emergency care.

Artificial intelligence has been touted as a boon to healthcare, but a new study has revealed its potential shortcomings when it comes to giving medical advice. (iStock)

“Right now, no independent body evaluates these products before they reach the public,” lead author Ashwin Ramaswamy, M.D., instructor of urology at the Icahn School of Medicine at Mount Sinai in New York City, told Fox News Digital.

“We wouldn’t accept that for a medication or a medical device, and we shouldn’t accept it for a product that tens of millions of people are using to make health decisions.”

Advertisement

Emergency scenarios

The team created 60 clinical scenarios across 21 medical specialties, ranging from minor conditions to true medical emergencies.

Three independent physicians then assigned an appropriate level of urgency for each case, based on published clinical practice guidelines in 56 medical societies.

WOMAN SAYS CHATGPT SAVED HER LIFE BY HELPING DETECT CANCER, WHICH DOCTORS MISSED

The researchers conducted 960 interactions with ChatGPT Health to see how the tool responded, taking into account gender, race, barriers to care and “social dynamics.”

While “clear-cut emergencies” — such as stroke or severe allergy — were generally handled well, the researchers found that the tool “under-triaged” many urgent medical issues.  

Advertisement

The team created 60 clinical scenarios across 21 medical specialties, ranging from minor conditions to true medical emergencies. (iStock)

For example, in one asthma scenario, the system acknowledged that the patient was showing early signs of respiratory failure — but still recommended waiting instead of seeking emergency care.

“ChatGPT Health performs well in medium-severity cases, but fails at both ends of the spectrum — the cases where getting it right matters most,” Ramaswamy told Fox News Digital. “It under-triaged over half of genuine emergencies and over-triaged roughly two-thirds of mild cases that clinical guidelines say should be managed at home.”

PARENTS FILE LAWSUIT ALLEGING CHATGPT HELPED THEIR TEENAGE SON PLAN SUICIDE

Under-triage can be life-threatening, the doctor noted, while over-triage can overwhelm emergency departments and delay care for those in real need.

Advertisement

Researchers also identified inconsistencies in suicide risk alerts. In some cases, it directed users to the 988 Suicide and Crisis Lifeline in lower-risk scenarios, and in others, it failed to offer that recommendation even when a person discussed suicidal ideations.

“ChatGPT Health performs well in medium-severity cases, but fails at both ends of the spectrum.”

“The suicide guardrail failure was the most alarming,” study co-author Girish N. Nadkarni, M.D., chief AI officer of the Mount Sinai Health System, told Fox News Digital.

ChatGPT Health is designed to show a crisis intervention banner when someone describes thoughts of self-harm, the researcher noted.

OpenAI launched ChatGPT Health, the medical-focused version of the popular chatbot tool, in January 2026. (Gabby Jones/Bloomberg via Getty Images)

Advertisement

“We tested it with a 27-year-old patient who said he’d been thinking about taking a lot of pills,” Nadkarni said. “When he described his symptoms alone, the banner appeared 100% of the time. Then we added normal lab results — same patient, same words, same severity — and the banner vanished.” 

“A safety feature that works perfectly in one context and completely fails in a nearly identical context … is a fundamental safety problem.”

CHATGPT HEALTH PROMISES PRIVACY FOR HEALTH CONVERSATIONS

The researchers were also surprised by the social influence aspect.

“When a family member in the scenario said ‘it’s nothing serious’ — which happens all the time in real life — the system became nearly 12 times more likely to downplay the patient’s symptoms,” Nadkarni said. “Everyone has a spouse or parent who tells them they’re overreacting. The AI shouldn’t be agreeing with them during a potential emergency.”

Advertisement

Fox News Digital reached out to Open AI, creator of ChatGPT, requesting comment.

Physicians react

Dr. Marc Siegel, Fox News senior medical analyst, called the new study “important.” 

“It underlines the principle that while large language models can triage clear-cut emergencies, they have much more trouble with nuanced situations,” Siegel, who was not involved in the study, told Fox News Digital. 

ChatGPT and other LLMs can be helpful tools, a doctor said, but they “should not be used to give medical direction.” (iStock)

“This is where doctors and clinical judgment come in — knowing the nuances of a patient’s history and how they report symptoms and their approach to health.”

Advertisement

ChatGPT and other LLMs can be helpful tools, Siegel said, but they “should not be used to give medical direction.”

“Machine learning and continued input of data can help, but will never compensate for the essential problem – human judgment is needed to decide whether something is a true emergency or not.”

BREAKTHROUGH BLOOD TEST COULD SPOT DOZENS OF CANCERS BEFORE SYMPTOMS APPEAR

Dr. Harvey Castro, an emergency physician and AI expert in Texas, echoed the importance of the study, calling it “exactly the kind of independent safety evaluation we need.”

“Innovation moves fast. Oversight has to move just as fast,” Castro, who also did not work on the study, told Fox News Digital. “In healthcare, the most dangerous mistakes happen at the extremes, when something looks mild but is actually catastrophic. That’s where clinical judgment matters most, and where AI must be stress-tested.”

Advertisement

Study limitations

The researchers acknowledged some potential limitations in the study design.

“We used physician-written clinical scenarios rather than real patient conversations, and we tested at a single point in time — these systems update frequently, so performance may change,” Ramaswamy told Fox News Digital.

CLICK HERE FOR MORE HEALTH STORIES

Additionally, most of the missed emergencies happened in situations where the danger depended on how the condition was changing over time. It’s not clear whether the same problem would happen with acute medical emergencies.

Because the system had to choose just one fixed urgency category, the test may not reflect the more nuanced advice it might give in a back-and-forth conversation, the researchers noted. 

Advertisement

ChatGPT Health is designed to show a crisis intervention banner when someone describes thoughts of self-harm. (iStock)

Also, the study wasn’t large enough to confidently detect small differences in how recommendations might vary by race or gender.

“We need continuous auditing, not one-time studies,” Castro noted. “These systems update frequently, so evaluation must be ongoing.”

‘Don’t wait’

The researchers emphasized the importance of seeking immediate care for serious issues.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

“If something feels seriously wrong — chest pain, difficulty breathing, a severe allergic reaction, thoughts of self-harm — go to the emergency department or call 988,” Ramaswamy advised. “Don’t wait for an AI to tell you it’s OK.”

The researchers noted that they support the use of AI to improve healthcare access, and that they didn’t conduct the study to “tear down the technology.”

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

“These tools can be genuinely useful for the right things — understanding a diagnosis you’ve already received, looking up what your medications do and their side effects, or getting answers to questions that didn’t get fully addressed in a short doctor’s visit,” Ramaswamy said. 

“That’s a very different use case from deciding whether you need emergency care. Treat them as a complement to your doctor, not a replacement.”

Advertisement

“This study doesn’t mean we abandon AI in healthcare.”

Castro agreed that the benefits of AI health tools should be weighed against the risks.

“AI health tools can increase access, reduce unnecessary visits and empower patients with information,” he said. “They are not inherently unsafe, but they are not yet substitutes for clinical judgment.”

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

“This study doesn’t mean we abandon AI in healthcare,” he went on. “It means we mature it. Independent testing and stronger guardrails will determine whether AI becomes a safety net or a liability.”

Advertisement

Related Article

ChatGPT dietary advice sends man to hospital with dangerous chemical poisoning
Continue Reading
Advertisement

Trending