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Brain health warning sign could be hiding in plain sight, say researchers

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Brain health warning sign could be hiding in plain sight, say researchers

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A new study from the University of Southern California suggests that the way blood pressure fluctuates from one heartbeat to the next may be just as important as the overall blood pressure reading — especially when it comes to brain health in aging adults.

Researchers found that older adults who experienced greater beat-to-beat changes in blood pressure had smaller brain volumes in areas tied to memory, and higher levels of a protein linked to nerve-cell injury.

“Even when blood pressure is well-controlled with medication, the rapid fluctuation in blood pressure from heartbeat to heartbeat is associated with worse memory and signs of brain shrinkage and brain cell injury,” USC Professor Daniel Nation, senior author of the study, told Fox News Digital.

The study linked rapid blood pressure shifts to smaller memory-related brain regions in older adults. (iStock)

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“Blood pressure isn’t static; it’s always adapting to the body’s needs,” he added in a press release. “But as we age, that regulation can become less precise.”

The study included 105 adults between the ages of 55 and 89. The researchers measured the participants’ blood pressure continuously for several minutes while they underwent brain scans. 

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In particular, they measured the stiffness of the adults’ arteries and how much their blood pressure changed between heartbeats.

Even when participants’ average blood pressure seemed healthy, those with the most erratic readings — combined with stiffer arteries — showed telltale signs of brain aging, the study found.

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People with erratic readings had smaller hippocampal and entorhinal cortex regions, which are among the first areas of the brain affected in Alzheimer’s disease.  (iStock)

Specifically, they had smaller hippocampal and entorhinal cortex regions, which are among the first areas of the brain affected in Alzheimer’s disease. They also had higher blood levels of neurofilament light, a biomarker of nerve-cell damage.

These findings were described as significant even after taking into account factors like age, sex and average blood pressure — suggesting that the fluctuations themselves, and not just overall pressure, may be a key risk factor.

The findings were first published online in the Journal of Alzheimer’s Disease on Oct. 17.

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For years, doctors have warned that high blood pressure raises dementia risk, but the USC study explores specifically how moment-to-moment instability can be a cause for concern.

Nation said the researchers were surprised to find that these rapid fluctuations in blood pressure were linked to brain injury, “regardless of whether they have hypertension or are treated with blood pressure-lowering medications.”

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In other words, someone could have “good” readings at the doctor’s office and still have dangerous spikes and dips that quietly stress the brain’s delicate blood vessels, the research suggests. Over time, that instability could contribute to memory decline and neurodegeneration.

Even well-controlled blood pressure may not protect against brain changes if readings fluctuate too much, the study suggests. (iStock)

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The researchers emphasized, however, that this study only shows correlation and does not prove causation, and that more research is needed.

“The findings are correlations in a cross-sectional study, which is like a snapshot in time,” Nation said. “Future studies should examine how these rapid blood pressure fluctuations change over time and whether they predict future brain shrinkage, brain cell injury and memory decline.”

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The team says there are currently no treatments specifically for these fluctuations.

“But it remains very important that people monitor their blood pressure and take blood pressure-lowering medications as prescribed in order to reduce their risk for brain injury and memory decline,” Nation said.

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“Development of therapies to address rapid blood pressure fluctuations should be a priority, since these rapid fluctuations are not fully addressed by existing treatments that focus on lowering average blood pressure,” he added.

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Experts reveal why ‘nonnamaxxing’ trend may improve mental, physical health

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Experts reveal why ‘nonnamaxxing’ trend may improve mental, physical health

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The key to feeling better in a fast, overstimulated world might be surprisingly simple: Live a little more like your grandparents.

A growing social media trend, dubbed “nonnamaxxing,” draws inspiration from the slower, more intentional rhythms associated with an Italian grandmother.

The lifestyle is often linked to activities like preparing home-cooked meals, spending time outdoors and making meaningful connections.

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“Nonnamaxxing is a 2026 trend that embraces the slower, more intentional lifestyle of an Italian grandmother (a Nonna). Think cooking from scratch, long family meals, daily walks, gardening and less screen time,” Erin Palinski-Wade, a New Jersey-based registered dietitian, told Fox News Digital.

Nonnamaxxing, derived from the name for an Italian grandmother, is a trend that incorporates lifestyle habits hundreds of years in the making. (iStock)

Stepping away from screens and toward real-world interaction can have measurable benefits, according to California-based psychotherapist Laurie Singer.

“We know that interacting with others in person, rather than spending time on screens, significantly improves mental health,” she told Fox News Digital, adding that social media often fuels comparison and lowers self-esteem.

LONELINESS MAY BE SILENTLY ERODING YOUR MEMORY, NEW RESEARCH REVEALS

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Living more like previous generations isn’t purely driven by nostalgia. Cooking meals from scratch, for example, has been linked to better nutrition and more mindful eating patterns.

Adopting traditional mealtime habits can improve diet quality and support both physical and mental health, especially when meals are shared regularly with others, Palinski-Wade noted.

One longevity expert stresses that staying healthy isn’t just about food — it’s also about joy and community. (iStock)

There’s also a psychological benefit to slowing down and focusing on one task at a time. Anxiety often stems from unfinished or avoided tasks, Singer noted, and engaging in hands-on activities can counteract that.

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“Nonnamaxxing encourages us to be present around a task, like gardening, baking or knitting, or just taking a mindful walk, that delivers something ‘real,’” she said.

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Palinski-Wade cautions against turning the trend into another source of pressure, noting that a traditional “nonna” lifestyle often assumes a different pace of life.

The key, she said, is adapting the mindset, not replicating it perfectly.

Nonnamaxxing, derived from the name for an Italian grandmother, is a trend that incorporates lifestyle habits hundreds of years in the making. (iStock)

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The goal is to reintroduce small, intentional moments that make you feel better.

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That might mean prioritizing a few shared meals each week, taking a walk without your phone or setting aside time for a simple hobby, the expert recommended.

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Singer added, “Having a positive place to escape to, through whatever activities speak to us and make us happy, isn’t generational – it’s human.”

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Loneliness may be silently eroding your memory, new research reveals

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Loneliness may be silently eroding your memory, new research reveals

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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.

Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.

Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.

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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.

Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)

“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.

The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.

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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.

Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)

Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.

About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.

DEMENTIA RISK SIGNALS COULD LIE IN SIMPLE BLOOD PRESSURE READINGS, SAY RESEARCHERS

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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.

The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.

Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)

Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.

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“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.

“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.

By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)

He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.

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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.

Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.

“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)

Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.

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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”

Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.

Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)

She said staying socially and mentally engaged is crucial for overall brain health.

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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”

The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.

Fox News Digital reached out to the researchers for comment.

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Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day

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Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day


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Eat More To Lose Weight? How Small Meals Boost Fat Burn




















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