Health
Aspirin may be linked to lower risk of colorectal cancer, new study suggests
Aspirin is widely known for its heart attack prevention benefits, but a new study has also linked the common drug to a reduced risk of colorectal cancer.
The study analyzed data from 107,655 men and women who participated in the Nurses’ Health Study and the Health Professionals Follow-Up Study over a three-decade span. It was published in JAMA Oncology on Thursday.
Researchers from Massachusetts General Hospital, Harvard Medical School and Washington University School of Medicine found that regular aspirin use was linked to a lower risk of colorectal cancer — especially for those with the unhealthiest lifestyles.
DAILY ASPIRIN AFTER A HEART ATTACK CAN REDUCE THE RISK OF FUTURE EVENTS, STUDY FINDS
“It shows an association between regular, low-dose aspirin use and decreased colon cancer use (close to 20%) in patients who are already at higher risk for several reasons, including smoking or poor diet,” said Dr. Marc Siegel, senior medical analyst for Fox News and clinical professor of medicine at NYU Langone Medical Center, who was not involved in the study.
Aspirin has been linked to a reduced risk of colorectal cancer, according to a study published in JAMA Oncology. (iStock)
Criteria for determining unhealthy lifestyles included higher body mass index, heavy smoking, higher alcohol intake, lack of physical activity and poor nutrition.
“We observed that participants in our study with the least healthy lifestyle had the greatest absolute benefit from aspirin use,” lead study author Daniel Sikavi, M.D., a board-certified physician at Massachusetts General Hospital, told Fox News Digital.
HEART ATTACK DEATH RISK CAN DOUBLE DURING HEAT WAVES AND HIGH POLLUTION, STUDY FINDS: ‘A PERFECT STORM’
“These participants had multiple risk factors that increased their overall risk of developing colorectal cancer, and our results show that aspirin can proportionally lower this markedly elevated risk.”
Among patients with a healthier lifestyle, the benefit from aspirin was still evident, but less pronounced.
Based on the findings, the researchers recommend that health care providers might consider recommending aspirin to patients with a less healthy lifestyle. (AP Photo/Emma H. Tobin)
“In the least healthy group, treating 78 patients with aspirin would prevent one case of colorectal cancer over 10 years, while it would take treating 909 patients to prevent one case in the healthiest group,” added Sikavi.
As to why aspirin decreases colon cancer risk, Siegel said it is likely due to the fact that the medication acts as an anti-inflammatory, and many cancers are associated with increased inflammation.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Based on the findings, the researchers suggest that health care providers consider recommending aspirin to patients with a less healthy lifestyle.
The American Cancer Society estimates that about 106,590 new cases of colon cancer and about 46,220 cases of rectal cancer will be diagnosed in 2024. (iStock)
“This work is an example of how we can move beyond one-size-fits-all strategies for cancer prevention by targeting effective preventive agents, such as aspirin, to the populations that are most likely to benefit,” Sikavi said.
Potential limitations
One limitation of the study was that the researchers did not systematically assess potential side effects associated with aspirin use, Sikavi noted.
For more Health articles, visit www.foxnews/health
“Because this was an observational study, it is possible there may have been additional factors that influenced our findings, although we rigorously accounted for a number of known risk factors for colorectal cancer,” he said.
Siegel reiterated that because this is an observational study, “it is still not proof.”
The American Cancer Society estimates that about 106,590 new cases of colon cancer and about 46,220 cases of rectal cancer will be diagnosed in 2024.
Health
The Best Time To Take Turmeric for Weight Loss and How To Maximize Results
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
Health
Doctor reveals what 30 days without alcohol does to the brain and body amid Dry January
NEWYou can now listen to Fox News articles!
After a season of bingeing and drinking, your body may feel like it needs a break from the party.
Dry January — a modern trend that challenges people to abstain from drinking for the first month of the year — has become a popular way to “detox” from the holidays and start the new year on a healthy note.
Research has linked alcohol to a variety of health conditions, ranging from hangovers to higher cancer risk.
5 POPULAR HANGOVER MYTHS THAT DON’T WORK AFTER HOLIDAY DRINKING, ACCORDING TO EXPERTS
In a recent podcast episode of “The Dr. Mark Hyman Show,” Dr. Mark Hyman, chief medical officer of Function Health, shared how 30 days of not drinking alcohol can transform health.
Hyman, who is based in Massachusetts, called Dry January a “powerful way to see in real time how alcohol affects nearly every system of your body and how quickly those systems can recover.”
Dry January has become a popular way to “detox” from the holidays and start the new year on a healthy note. (iStock)
Alcohol’s toll on the brain and body
Hyman acknowledged that most people drink to feel happier and more comfortable in social situations. This effect is caused by the main ingredient in alcohol, called ethanol, which can also have toxic effects.
Instead of stimulating the brain, alcohol slows it down and loosens inhibitions. “You feel more relaxed, more social, more confident, maybe you feel a little euphoric,” Hyman said.
Alcohol’s effect on the brain can also lead to poorer decisions and slower reflexes, the doctor cautioned.
Drinking alcohol can cause cognitive decline and brain fog, experts warn. (iStock)
Drinking also impacts the prefrontal cortex of the brain, which Hyman described as “the adult in the room,” responsible for judgment, planning and restraint. “It goes offline early in drinking, which explains why people feel freer or act impulsively when they drink,” he said.
Even moderate drinking can cause metabolic stress, inflammation, impaired detoxification and hormonal shifts, Hyman said, which can impact nearly every organ system in the body.
POPULAR WEIGHT-LOSS DRUGS COULD TAKE THE EDGE OFF YOUR ALCOHOL BUZZ, STUDY FINDS
Alcohol consumption has also been linked to an increased risk of cancer, metabolic dysfunction, gut microbiome disturbances and mitochondrial toxins.
It can also prevent the body from falling into REM sleep, which is the deep rest recovery period when the immune system cleans out the day’s toxins, according to Hyman.
Alcohol can impact deep rest and mental health, according to experts. (iStock)
Memory loss, cognitive decline, anxiety, sleep disruption, dementia and cardiovascular disease are all known risks of long-term alcohol use, as well as liver complications like fatty liver disease.
“Bottom line, alcohol taxes every major system in your body, especially your liver, your brain, your gut, your hormones,” Hyman said.
The effects of 30 days with no alcohol
The first week after your last drink, the body begins to detoxify and reset, according to Hyman. Blood sugar and cortisol stress hormones level out, and the liver begins to process a “backlog of toxins.” The body also re-hydrates and re-energizes.
The first 30 days with no alcohol allows the body to balance itself out. (iStock)
The second week, the gut and brain will begin to re-balance, as hormones like serotonin and dopamine stabilize, gut inflammation drops and the microbiome begins to heal. Cravings for sugar and alcohol will wane and mental clarity returns, the doctor said.
Week three is marked by further decreases in inflammation, fatty liver and blood pressure. This can be noticeable in the skin, as puffiness and redness are reduced. Mood also begins to stabilize, with lower anxiety levels.
DOCTORS REVEAL WHY ALCOHOL CAUSES ‘BOOZE BUTT’ AND HOW TO PREVENT IT ON NEW YEAR’S
In week four, the body experiences additional metabolic and immune benefits, Hyman shared, including more insulin sensitivity, which makes it easier to lose weight.
“You have a stronger immune response. You’re not getting sick as much. You have better deep sleep, balanced hormones, especially cortisol and testosterone,” he said. “And you see a big change in energy, confidence and focus.”
Abstaining from alcohol can help restore energy, according to experts. (iStock)
Dr. Pinchieh Chiang, a clinician at Circle Medical in San Francisco, said that Dry January isn’t a “detox,” but rather provides “feedback” from the body.
“It gives the body time to show people how it feels without alcohol. For many, that insight alone changes their relationship with drinking,” she said. “The biggest surprise isn’t what people give up, it’s how much better they feel.”
HIGHER STROKE RISK LINKED TO CONSUMING CERTAIN AMOUNT OF ALCOHOL, STUDY FINDS
The doctor confirmed that the first few days of not drinking may feel harder than expected, sometimes causing restlessness, cravings or disrupted sleep, but Dry January can ultimately change drinking habits for the remainder of the year.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
After a full year without alcohol, Chiang noted that health improvements are more profound. “We see sustained improvements in blood pressure, liver function and inflammation,” she said. “Those changes directly affect long-term heart disease and stroke risk.”
The risks of ‘all or nothing’
Some experts warn that adopting the Dry January trend could strengthen the urge to drink more in the other months, noting that some drinkers may find more success by slowly consuming fewer drinks per week.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Thomas Stopka, Ph.D., an epidemiologist and professor in the public health and community medicine department at Tufts University School of Medicine in Massachusetts, shared in a Futurity report that for some people, “damp January” may be more suitable.
One expert warned that not all drinkers should quit “cold turkey,” as it could lead to severe withdrawals. (iStock)
“Dry January is well-intentioned, and it may work really well for the people who can stick to it, maybe even beyond January,” he said. “Other people may be more inclined to cut down on alcohol consumption rather than quit drinking completely for the month.”
CLICK HERE FOR MORE HEALTH STORIES
Stopka noted that successful harm-reduction approaches “aim to be judgment free.”
“Substance use disorder is a disease,” he said. “It takes time to treat the disease and to stay connected to the continuum of care — from prevention to treatment initiation to sustained therapy, whether through medication, self-help, or individual therapy or group support.”
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
Those struggling with signs of alcohol use disorder should consult a medical professional for personalized guidance.
Fox News Digital reached out to several alcohol industry associations requesting comment.
Health
The Best Weight Loss Medications and Supplements in 2026
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
-
Detroit, MI1 week ago2 hospitalized after shooting on Lodge Freeway in Detroit
-
Technology5 days agoPower bank feature creep is out of control
-
Dallas, TX6 days agoDefensive coordinator candidates who could improve Cowboys’ brutal secondary in 2026
-
Dallas, TX2 days agoAnti-ICE protest outside Dallas City Hall follows deadly shooting in Minneapolis
-
Delaware2 days agoMERR responds to dead humpback whale washed up near Bethany Beach
-
Iowa4 days agoPat McAfee praises Audi Crooks, plays hype song for Iowa State star
-
Health7 days agoViral New Year reset routine is helping people adopt healthier habits
-
Nebraska4 days agoOregon State LB transfer Dexter Foster commits to Nebraska