World
WHO to roll out malaria vaccine in Africa even as funding dips
Because the World Well being Group declares the following step in its distribution of the world’s first authorised malaria vaccine in three African international locations, considerations about its worth have come from an unlikely supply: the Invoice and Melinda Gates Basis, arguably the vaccine’s greatest backer.
WHO endorsed the vaccine final fall as a “historic” breakthrough within the battle towards malaria however the Gates Basis informed The Related Press (AP) information company this week it can not financially help the shot.
Some scientists say they’re mystified by that call, warning it might depart thousands and thousands of African kids vulnerable to dying from malaria in addition to undermine future efforts to resolve intractable issues in public well being.
The vaccine, offered by GlaxoSmithKline (GSK) as Mosquirix, is about 30-percent efficient and requires 4 doses.
The malaria vaccine has “a a lot decrease efficacy than we wish,” Philip Welkhoff, the Gates Basis’s director of malaria programmes, informed the AP.
Explaining its determination to finish help after spending greater than $200m and several other many years getting the vaccine to market, he stated the shot is comparatively costly and logistically difficult to ship.
“If we’re attempting to save lots of as many lives with our present funding, that cost-effectiveness issues,” he stated.
The Gates Basis’s determination to pivot away from supporting the rollout of the vaccine in Africa was made years in the past after detailed deliberations, together with whether or not the muse’s cash could be higher spent on different malaria vaccines, therapies or manufacturing capability, Welkhoff stated.
A number of the sources which may have gone into getting the vaccine to international locations have been redirected to purchase new insecticidal nets, for instance.
“It’s not the best vaccine on the earth, however there are methods of utilizing it that might have a big effect,” stated Alister Craig, the dean of organic sciences at Liverpool Faculty of Tropical Medication.
The world is struggling to include the spike in malaria seen because the coronavirus pandemic disrupted efforts to cease the parasitic illness, which killed greater than 620,000 folks in 2020 and brought about 241 million instances, primarily in kids below 5 in Africa, Craig stated.
“It’s not like we’ve a whole lot of different options,” Craig stated. “There could possibly be one other vaccine authorised in about 5 years, however that’s a whole lot of lives misplaced if we wait till then,” he stated, referring to a shot being developed by Oxford College.
BioNTech, creator of the Pfizer COVID-19 vaccine, plans to use the messenger RNA expertise it used for the coronavirus to malaria, however that mission is in its infancy.
One other massive impediment is availability; GSK says it may possibly solely produce about 15 million doses per 12 months till 2028. WHO estimates that to guard the 25 million kids born in Africa yearly, no less than 100 million doses yearly is perhaps wanted.
Though there are plans to switch the expertise to an Indian drugmaker, it will likely be years earlier than any doses are produced.
“All the cash on the earth” wouldn’t alleviate the vaccine’s short-term provide constraints, stated Welkhoff, of the Gates Basis.
He famous that the Gates Basis continues to help the vaccines alliance Gavi, which is investing almost $156m into making the shot initially accessible in three African international locations: Ghana, Kenya and Malawi.
“We’re supporting the roll-out through the Gavi funding, however we determined we’d not dedicate further direct funding to increase the availability of the vaccine,” Welkhoff stated.
On Thursday, WHO and Gavi invited growing international locations to use for funding to pay for the malaria vaccine of their international locations.
“If delivered to scale, the vaccine will assist to forestall thousands and thousands of instances of malaria, save tens of hundreds of lives and guarantee a brighter future for the continent,” stated Dr Matshidiso Moeti, WHO’s Africa director.
The Gates Basis’s withdrawal of economic help for the malaria vaccine may unnerve others, Dr David Schellenberg of the London Faculty of Hygiene and Tropical Medication, stated.
“There’s a danger that this might discourage others who’re contemplating financing the malaria vaccine and even be a disincentive for folks engaged on different vaccines,” he stated. He stated that combining the vaccine’s use with different measures, like distributing medication throughout malaria’s peak season might dramatically scale back instances and deaths.
“We nonetheless see folks coming in with 4 or 5 episodes of malaria a 12 months,” he stated. “We don’t have a magic bullet, however we might make higher use of the instruments we do have.”
An imperfect distribution of the vaccine would nonetheless save lives, Dr Dyann Wirth, an infectious ailments skilled at Harvard College, stated.
“We’d like to have 100 million doses, however that sort of cash doesn’t exist for malaria,” she stated. “The 15 million doses we’ve remains to be 15 million alternatives to guard kids that we didn’t beforehand have.”
The Gates Basis had accomplished its half in bringing the vaccine to market and it’s now as much as international locations, donors and different well being organisations to make sure it’s used, she stated.
The vaccine, even with its imperfections, is eagerly awaited in Malawi.
Nolia Zidana, 32, stated she is eager to get her two younger sons immunised after seeing malaria sicken them quite a few instances – and surviving it herself.
“Rising up with my mother and father and siblings, we’ve been sick from malaria on a regular basis,” stated Zidana, who lives in Malawi’s central Ntcheu district. “My elder son has had malaria numerous instances inside the 4 years that he has been round. Whereas simply at seven months outdated, twice my youthful son has already been down with malaria,” she stated.
She stated though they sleep below mosquito nets, typically they get bitten earlier than going to mattress as they’re getting ready meals for supper at the hours of darkness of the night.
“We hear different folks use mosquito repellents or burn anti-mosquito incense coils, which we can’t afford as we’re simply peasant farmers that stay from hand to mouth,” she stated.
Dr Michael Kayange of Malawi’s well being ministry urged everybody within the nation to take no matter measures they’ll to curb malaria. Immunisation itself is inadequate to cease the illness and other people ought to undertake a number of methods, he stated.
“Even simply by sleeping below a mosquito web, you’ve got performed your position in decreasing the malaria burden within the nation,” he stated.
World
European Ministers Visit Syria to Strengthen Ties With New Government
Syria’s new leaders met the French and German foreign ministers in the capital, Damascus, on Friday in one of the highest-level Western diplomatic visits since the fall of President Bashar al-Assad last month.
Annalena Baerbock of Germany and her French counterpart, Jean-Noël Barrot, arrived in Damascus for the first such trip in years on behalf on the European Union, as world powers have begun building ties with Hayat Tahrir al-Sham, the Islamist group that leads the new Syrian government.
Ms. Baerbock and Mr. Barrot met with Ahmad al-Shara, the group’s leader, after visiting the notorious Sednaya prison, where Mr. al-Assad’s regime had tortured and killed thousands of detainees.
“We are traveling to Damascus today to offer our support, but also with clear expectations of the new rulers,” Ms. Baerbock said in a statement before the meeting. “A new beginning can only happen if all Syrians, no matter their ethnicity and religion, are given a place in the political process.”
The visits are among a flurry of contacts between rebel leaders and Western officials looking to gradually open channels to the new Syrian authorities. Mr. al-Shara has worked to project a moderate image since taking power.
Hayat Tahrir al-Sham is still blacklisted as a terrorist group by the United States and the United Nations because of its past ties to Al Qaeda. Mr. al-Shara has called on the international community to remove that designation and sought to reassure minority groups, saying he wants to focus on rebuilding Syria after years of civil war.
“The current events demand the lifting of all sanctions on Syria,” he said in a televised interview last month.
Mr. Barrot said that France was urging the new rulers in Damascus to pursue a political transition that would allow “all the communities in Syria, in all their diversity, to be represented.” Part of that included reaching a “political solution” with the Kurdish minority, he said, which has carved out an autonomous region in northeastern Syria.
The diplomacy comes during a realignment across the Middle East, where Mr. al-Assad’s regime was a core part of Iran’s regional coalition. His family’s decades of iron-fisted rule were opposed by many Syrians, spurring the 2011 uprising and civil war. At least six foreign militaries were involved in the fighting, including those from Iran, Russia and Turkey.
Many countries — including the United States — have begun forging ties with the new government. In late December, Barbara Leaf, the senior State Department official for the Middle East, met with Mr. al-Shara in Damascus and told him that Washington would no longer pursue an outstanding bounty for his arrest.
Some Syrians — particularly Christians and other minority groups — are uncertain about Mr. al-Shara, pointing to Hayat Tahrir al-Sham’s conservative Islamist roots. In Idlib, a province controlled by the group since 2017, its leaders banned buying and selling alcohol and opened a chain of free religious schools. But Mr. al-Shara’s faction has eschewed the draconian decrees and brutal punishments of extremists like the Taliban and the Islamic State.
In a sign of the jitters among some Syrians, a posting on a Facebook page run by the Education Ministry this week described a new curriculum that was interpreted by some as taking a more Islamist slant.
It was not clear whether any of the changes had been implemented, but the minister of education, Nadhir Al-Qadri, said in a statement that the curriculum was unchanged except for the removal of “content glorifying the Assad regime” and the addition of images of the Syrian revolutionary flag.
Officials in Hayat Tahrir al-Sham have laid out an ambitious plan for establishing a new government, and rebel leaders have assumed key positions to oversee a transition. They say they are establishing a caretaker government in consultation with Syrians of all backgrounds, as well as a committee to draft a new Syrian constitution.
Many in the region are also wary of the new Syrian government, including Gulf States like the United Arab Emirates, which has long tried to prevent the rise of groups that embrace political Islam, as well as Israel.
Overnight on Friday, Israeli warplanes bombed Syrian defense research sites near Aleppo, according to the Syrian Observatory for Human Rights, a war monitoring group. There were no immediate reports of casualties. Israel declined to comment on the report.
Israel has conducted hundreds of airstrikes against Syrian military sites since the fall of Mr. al-Assad in an effort to eliminate sophisticated arms like chemical weapons and long-range missiles. Mr. al-Shara has said he will uphold a longstanding cease-fire agreement with Israel, saying that Syria poses no threat to its neighbors.
Here are other developments in the region:
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Houthi missile attacks: The Iran-backed Houthi militia in Yemen launched a ballistic missile at Israel before dawn on Friday, setting off air-raid sirens across central Israel, including in Jerusalem. The Israeli military said it had intercepted the missile and there were no reports of serious casualties. Israeli fighter jets have flown over 1,000 miles to strike Houthi-controlled areas in Yemen but Israel has struggled to stop the attacks, which have escalated over the past month.
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Northern Gaza hospital: The Israeli military is operating near the Indonesian Hospital in northern Gaza, from which many doctors and patients have already fled, health officials there said, noting that the sound of gunfire could be heard outside. The Israeli military said it did not intend to evacuate the hospital. The Israeli military raided Kamal Adwan, another northern Gaza hospital, last week, charging that Hamas was operating in the compound. Israeli troops apprehended at least 240 people they said were militants, including Hussam Abu Safiya, the hospital director; Amnesty International has called for his release.
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Israeli strikes in Lebanon: The Israeli military said on Thursday night that it had bombed Hezbollah sites in southern Lebanon, while a 60-day truce largely continues to hold. Since the agreement went into effect in late November, Israel has repeatedly bombarded what it says are Hezbollah fighters violating the agreement. Hezbollah has generally refrained from responding militarily. The current cease-fire is set to expire in late January, although the United States and its allies hope it becomes permanent.
Abu Bakr Bashir and Aurelien Breeden contributed reporting.
World
Elon Musk demands UK act on grooming gang scandal amid growing calls for probe: 'National inquiry now!'
SpaceX CEO Elon Musk is throwing his weight behind growing calls for a new investigation into the scandal of child abuse by grooming gangs, going so far as to back calls for King Charles III to intervene.
“National inquiry now!” Musk stated on X on Friday, declaring the scandal “the worst mass crime against the people of Britain ever.”
The U.K. has for years been dealing with the revelation that a number of grooming gangs, often consisting of men of South Asian or British Pakistani heritage, exploited children for decades across the north of England in cities and towns including Rochdale, Telford, Manchester and Rotherham.
BRITAIN HIT BY ANOTHER ASIAN GROOMING GANG SCANDAL AS REPORT EXPOSES CHILD SEX ABUSE IN MANCHESTER
A 2014 independent review of grooming in Rotherham found that the majority of perpetrators were of Pakistani heritage and said that it was “hard to describe the appalling nature of the abuse that child victims suffered.”
“They were raped by multiple perpetrators, trafficked to other towns and cities in the north of England, abducted, beaten, and intimidated. There were examples of children who had been doused in petrol and threatened with being set alight, threatened with guns, made to witness brutally violent rapes and threatened they would be next if they told anyone,” the report said. “Girls as young as 11 were raped by large numbers of male perpetrators.”
That report found that around 1,400 children were abused between 1997 and 2013. It also stressed that abuse “is not confined to the past but continues to this day.”
The report found that police gave no priority to the abuse cases and failed to act. It also found that at least one report “was effectively suppressed” and others were ignored by local authorities. It found that while some did not believe the information, others were spooked by political correctness.
“Several staff described their nervousness about identifying the ethnic origins of perpetrators for fear of being thought racist; others remembered clear direction from their managers not to do so,” it said.
1,510 CHILDREN ABUSED IN ROTHERHAM SEX SCANDAL, NEW REPORT SAYS
A review in Telford found that a high proportion of the cases involved men described as “Asian” or “Pakistani” and that authorities in Telford were concerned that allegations “had the potential to start a ‘race riot.’” A broader Home Office report in 2020 said that while high-profile cases have “mainly involved men of Pakistani ethnicity,” it also cited research showing that group-based child sex exploitation offenders are most commonly White.
The scandal was seen by many as a prioritizing of multiculturalism and political correctness over the welfare of British children and the prosecution of criminals.
The issue recently reignited when local politicians in the town of Oldham asked the Home Office in July for a government inquiry into child abuse. A 2022 report into Oldham’s actions between 2011 and 2014 found that children were failed by local agencies, but it also found that there was no cover-up despite “legitimate concerns” that the far-right would capitalize on “the high-profile convictions of predominantly Pakistani offenders across the country.”
The Manchester Evening News reported Home Office Minister Jess Phillips responded to the request in October, saying that any such inquiry should be organized locally.
“Survivors sit at the heart of our work to end child sexual exploitation. Whatever happens in terms of future inquiries, we have promised them that their wishes will be paramount, and we will not renege on that pledge,’ a Home Office spokesperson told the outlet.
20 MEN FOUND GUILTY OF RAPING MORE THAN A DOZEN TEENAGE GIRLS IN NORTHERN ENGLAND
“We all recognize that terrible mistakes were made in the past, with children ignored or dismissed,” they said.
That response was slammed by Conservative Party Leader Kemi Badenoch, who called for a full national inquiry into what she called the “rape gangs scandal.”
“The time is long overdue for a full national inquiry into the rape gangs scandal,” she said on X. “Trials have taken place all over the country in recent years but no one in authority has joined the dots.”
“2025 must be the year that the victims start to get justice,” she said.
Musk, who has been tapped by President-elect Trump to lead the Department of Government Efficiency, also backed calls for King Charles III to intervene-noting that current Prime Minister Keir Starmer was head of the Crown Prosecution Service at the time of the scandals, although the scandals generally involved local authorities.
“Yes,” Musk said in response to a post saying the King “must step in.”
He continued, “They oppose an inquiry, because it will show that those in power were complicit in the cover-up,” he said of the government.
Health Secretary Wes Streeting responded to Musk’s comments, telling ITV News that the government takes child abuse “incredibly seriously” and repeating that an inquiry in Oldham should be led locally.
“Some of the criticisms that Elon Musk has made, I think are misjudged and certainly misinformed, but we’re willing to work with Elon Musk, who I think has got a big role to play with his social media platform to help us and other countries to tackle this serious issue,” he said. “So if he wants to work with us and roll his sleeves up, we’d welcome that.”
Fox News Digital reached out to the British government’s Home Office for comment.
The Associated Press contributed to this report.
World
Calls for boldness and stability at Bayrou's first ministers' meeting
The new government’s priorities under François Bayrou are to adopt the 2025 budget and reduce the public deficit.
French President Emmanuel Marcon called for boldness and stability at the first Council of Ministers meeting held by François Bayrou’s new government.
As is the tradition at the start of the new year, the ministers first met at the Ministry of the Interior for a breakfast.
The 35 ministers then crossed the street in close ranks to join Emmanuel Macron at the Élysée Palace.
“This government was born in the turmoil of a major political crisis. You know the picture: censure, the breakdown of majorities, the rise of extremes,” declared government spokeswoman Sophie Primas at a press conference.
She called on “everyone” to “shoulder their responsibilities” and “move away from inflexible positions” in favour of “demanding” and “going beyond”, rather than “obstructing”.
Budget vote
The government’s priority is to adopt the 2025 budget.
The rating agencies, financial markets and the European Commission are also urging France to reduce its deficit in order to comply with EU rules on budgetary discipline.
The Stability and Growth Pact sets the debt ceiling at 60% of GDP and a public deficit ceiling at 3% of GDP.
The public deficit was 6.1% of GDP in 2024, and the government’s target is to reduce it to 5.4% of GDP in 2025. The previous, and more ambitious target set by former Prime Minister Michel Barnier, was 5% in 2025.
Mayotte, devastated by cyclone Chido, is also awaiting a bill promised by François Bayrou earlier this week.
Emmanuel Macron appointed François Bayrou as the new Prime Minister on 13 December 2024, and tasked him with forming a new government. The composition of the government was announced on 23 December 2024.
Michel Barnier’s previous government was toppled on 4 December following the adoption of a motion of censure in the National Assembly.
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