The Arizona Cardinals travel to face the San Francisco 49ers in a crucial Week 5 NFC West battle that can see the squad either claim back some momentum or fall into a 1-4 hole to begin the year.

Both sides of the ball have tough tasks ahead of them when it comes to containing the 49ers – can Jonathan Gannon’s squad come out on top?

Our staff predictions reveal…. probably not.

Donnie Druin – Which Cardinals squad will show up? If we see what the Cardinals flashed in Week 2 against the Rams, we could be in business. However, Arizona’s been far too inconsistent to give any faith as road underdogs – especially against a 49ers team regardless of who suits up on the other side. Unless the Cardinals truly solved their defensive woes in one week, this could get bad. SF 30, AZ 17

Kevin Hicks – This could be something of a trap game for San Francisco – who handled a clearly inferior New England Patriots offense last week. The overall injury outlook is looking worse for them, and although the Cardinals aren’t the ‘07 Patriots, they have competed against two of the top five squads in the league this season. Expect a bounce back week for Kyler Murray, and for James Conner to make a mark, but the home field advantage and Brock Purdy’s MVP-level play this season result in the Niners pulling away in the 4th frame. SF 30, AZ 23

Jack London – it’s hard to come back from a game like the one Arizona had against a Super Bowl Contender. It’s not the offense I’m worried about in this game, but the defense, as Brock Purdy and Kyle Shanahan’s scheme had no issues putting up points last year. I don’t see that changing this year, even though I expect Kyler to play better along with the whole offense. Still not enough for an Arizona win though. SF 33 AZ 21

Kyler Burd – We are now three weeks out from an offensive performance against the Rams that is looking more and more like a flash in the pan. The offense and defense have alternated periods of decency with full quarters of dysfunction. This inability to get both phases operating at once has led to two straight losses, a close one against a very good Lions squad and an abysmal, embarrassing one against the Washington Commanders and former head coach Kliff Kingsbury. With as much flack as the offense has received from fans this past week, I do think Kyler Murray and the offense as a whole will look more competent, but expecting this sieve of a defense to do much against one of the most consistently good teams in the NFC is a fool’s errand. On the road, against a great roster and coach in Kyle Shanahan, I can’t see a way the Cardinals come out with a win. SF 34, AZ 21

Richard Bradshaw – The Cardinals were humiliated at home by the Commanders. To their defense, Jayden Daniels is playing like a legitimate league MVP candidate as a rookie, but there’s no excuse for the way the Washington defense bullied the Cards. I am worried about the direction of this team moving forward and a trip to The Bay to play a 49ers team that is trying to get their season back on track is not remotely ideal. Even if this game was in the desert, I’d still have the 49ers big. The Cards offense COULD rebound, but I’m not betting on it against a defense hosting Nick Bosa, Fred Warner, and company. I also doubt Arizona’s defense is prepared for San Francisco’s almighty offense. I got the Niners big in this one. SF 38, AZ 10

SAN FRANCISCO (AP) — When London Breed was elected as San Francisco’s first Black woman mayor, it was a pinch-me moment for a poor girl from public housing whose ascension showed that no dream was impossible in the progressive, compassionate and equitable city.

But the honeymoon was short-lived as a COVID-19 pandemic shuttered stores and tech workers retreated to home offices. Tent encampments surged and so did public drug use.

Breed now finds herself in a pricey campaign as she battles for a second term.

The moderate Democrat faces four main challengers on the Nov. 5 ballot, all fellow Democrats, who say Breed has squandered her six years in office. They say she allowed San Francisco to descend into chaos and blamed others for her inability to rein in homelessness and erratic street behavior, all while burglarized businesses pleaded for help.

Her closest competitors appear to be Mark Farrell, a former interim mayor and venture capitalist who is the most conservative of the group, and Daniel Lurie, an anti-poverty nonprofit founder and an heir to the Levi Strauss fortune who has pumped at least $6 million of his own money into his first bid for mayor.

The other two are Aaron Peskin, president of the Board of Supervisors, the most liberal of the candidates, and Ahsha Safaí, a city supervisor and former labor organizer.

Streets have become cleaner and homeless tents much harder to find, but the daytime shooting in September of 49ers rookie Ricky Pearsall in a popular central shopping district reignited the public safety issue.

“Even though San Francisco is seen as this kind of West Coast liberal icon, the city has experienced a series of episodes that challenge that, and that puts voters into kind of a testy mood,” said David McCuan, a political science professor at Sonoma State University.

McCuan added that he thinks Breed still has the advantage, but “she’s just got difficulties around her.”

The Nov. 5 vote in a presidential election year is happening amid a national debate on public safety and a statewide vote on a tough-on-crime proposition that would, if approved, reclassify some misdemeanor theft and drug crimes as felonies.

Voters concerned over crime ousted progressive San Francisco prosecutor Chesa Boudin in a rare recall in 2022, and across the bay this year, the Oakland mayor is facing a recall election due in part to crime concerns.

In an interview, Breed, 50, said San Francisco is turning a corner — thanks to her hard work — and voters she meets are upbeat.

She championed a pair of successful public safety ballot measures in the March primary to expand police powers and compel some people into drug treatment. She ordered a crackdown on homeless tent encampments following a U.S. Supreme Court decision that said bans on outdoor sleeping are allowed. Reported crime is down.

“We laid the groundwork, and now people are reaping the benefits of our infrastructure projects, the capacity we built and the technology we’re using to combat crime,” Breed said, adding that voters “know that someone’s in charge and making it happen.”

Farrell challenged that notion at a meeting with voters at a boisterous gastropub on a recent evening, saying Breed failed to maintain the streets he cleared of tents when he was interim mayor in 2018. Farrell, 50, was a city supervisor who served in the role for six months following the death of Mayor Ed Lee.

He envisions a San Francisco where police feel respected and older residents don’t have to hire private security when the city has a $15 billion annual budget.

“San Franciscans, given the state of our city right now, want not only a change of leadership, but a sense of direction for the city,” Farrell said in an interview this week.

Lurie, 47, says voters deserve a true public servant and that as a political outsider, he has the experience to overhaul corrupt government bureaucracy.

Voters are “desperate, desperate for someone that is going to come in there and bring accountability,” Lurie said.

As founder of the nonprofit Tipping Point Community, he says, he built tiny cabin shelters and permanent subsidized housing at a fraction of the cost and time that it would take City Hall.

Breed, Farrell and Lurie all have strong ties to wealthy business donors.

Lurie leads in fundraising with more than $13 million, including $1 million from his mother, businesswoman Miriam Haas, to an outside committee supporting his candidacy. Breed has collected more than $4.6 million, including $1.2 million from former New York City Mayor Michael Bloomberg, while Farrell has raised $3.5 million.

All three candidates also carry baggage.

Breed is embroiled in an unfolding scandal over financial mismanagement in the Dream Keeper Initiative, her marquee racial equity program for Black communities. The mayor says the program does good work.

Farrell has been accused by opponents of dodging campaign contribution limits by pooling staff and office costs with a campaign he established in support of a ballot measure, which can accept unlimited donations. Farrell says he is following the law.

And critics of Lurie say the affordable housing project his nonprofit built cannot be replicated citywide because it used a construction method opposed by local labor unions and required massive private investment. Lurie says naysayers will naysay.

San Francisco elects its mayor using a ranked choice voting system that could yield a winner who did does get the most first-place votes. It also can encourage unusual alliances between rival candidates and, indeed, this week Farrell and Safaí agreed to ask their supporters to make the other their No. 2 pick.

Breed won election as mayor in June 2018 to serve out the remainder of Lee’s term and was reelected in 2019 to a full term that has lasted five years instead of the typical four after voters changed the election calendar to line up with presidential contests.

SAN FRANCISCO (KGO) — With just about a month left until the November election, the top candidates in the race for San Francisco mayor are battling to be voters’ top choice.

In interviews with the four leading candidates, ABC7 News anchor Reggie Aqui teamed up with our media partner The San Francisco Standard and its political and business reporter Annie Gaus, along with Kara Swisher, author and host of the “On with Kara Swisher” podcast. Our panel asked the candidates about some of the biggest issues facing the city: including public safety and crime, homelessness, downtown recovery and the economy, tourism and public perception of the city.

WATCH: Top San Francisco mayoral candidates detail vision for city, tackling crime, homelessness and more

All four candidates – Mayor London Breed, Aaron Peskin, Mark Farrell and Daniel Lurie – were in agreement about the severity of the homelessness problem in San Francisco, but they all differ in approaches for solutions.

In recent years, especially following the pandemic, San Francisco has struggled like other major metropolitan areas. But the city has particularly been the target of conservative media outlets or politicians, blaming Democratic policies for the city’s struggles.

All four candidates acknowledged the city has had a PR problem, but maintained their love for San Francisco and its ability to bounce back as a crown jewel of the West Coast.

Farrell: city perception cannot change until problems solved

Former interim mayor Mark Farrell said it’s going to take a leader who can help rapidly solve some of San Francisco’s biggest issues before the city’s reputation can actually be restored.

“Unless you fix the underlying issues that are truly making it tough for people who live here – but also people that visit here – to me, it’s like lipstick on a pig, right? We need to have sustainable growth, sustainable difference in San Francisco,” Farrell said.

He said he will also prioritize marketing the city to the business and tourist community.

Lurie says he knows how to deliver on big projects

Levi’s heir and nonprofit executive Daniel Lurie said his years of experience at the helm of Tipping Point, his antipoverty nonprofit, makes him the most qualified in these types of projects.

“I’ve housed over 40,000 people since 2015. I know how to get big things done. And the key component of all of it is holding people accountable. If you want more of the same, you got four other people to choose from. If you want something different, if you want change in this city, I’m all I’m here for it,” Lurie said.

Lurie also touted his work on Super Bowl 50, saying then-Mayor Ed Lee reached out to him to chair the bid to bring the Super Bowl to San Francisco.

“It wasn’t because I was a sports guy. It was because he knew that I could deliver and we did. We brought a global sporting event $240 million of economic revenue,” he said.

Peskin: Board experience taught him to “work with people” on major issues

Aaron Peskin – longtime SF politician and current President of the Board of Supervisors – says his years of working with different types of people on the board has taught him cooperation, which he thinks will be key in tackling some of these issues.

“I try to figure out what the best path forward is. I work with experts. I try to bring people together,” he said.

Peskin cited his recent work with Mayor London Breed on a mixed-use zoning project downtown, despite her being his current political opponent.

“The work that Mayor Breed and I did to change the zoning downtown, to build more housing; the work that I’m doing with my colleagues, to provide more affordable financing so we can address our housing crisis. But ultimately you listen to people and then you implement,” he said.

Breed says SF is on the rise again thanks to her leadership

Public safety and crime are main contributing factors when it comes to the international view of San Francisco in recent years.

Recent incidents – like the shooting of 49ers wide receiver Ricky Pearsall – have garnered negative national attention for the city. But the incumbent mayor insists, San Francisco’s overall numbers are trending in the right direction.

Breed said crime rates are improving, largely due to newer technology police departments are able to take advantage of.

“Crime is lower than it’s been in a decade. And one of the great things we have now that we didn’t have before was 21st century technology. Never in the history of our police department were we able to use drones and cameras and other equipment, which has led to a remarkable change around crime,” she said.

But the mayor acknowledges, there are still improvements to be made across the board.

“We are well on our way. And when I say well on our way, many larceny thefts overall are down, especially car break ins,” Breed said. “This year, we’re excited about the new numbers, the new data. But again, unless you feel it, we of course still have work to do. And I acknowledge that.”

You can watch the full interviews with all four candidates, here.