MOUNTAINAIR, N.M. – Investigators say they could have answers within the next 24 hours about a mysterious substance that killed three people inside a Mountainair home and sickened more than two dozen others.

Officials are expected to provide an update Friday on what exactly caused the deadly incident, which has raised serious questions about exposure risks for both humans and animals.

Growing Impact: From victims to first responders

The incident began Wednesday when four people were found unresponsive at a home after coming into contact with an unknown substance. Two were declared dead on scene, and the other two were given Narcan, resuscitated and taken to UNM Hospital. One of them died after arriving at the ER. Initially reported as an overdose call, the situation quickly escalated.

More than 25 people — including at least 18 first responders — were exposed and required quarantine at UNM Hospital. Most have since been released, but two individuals remain under observation as of Wednesday night.

Mountainair Mayor Peter Nieto said the town’s EMS chief, Josh Lewis, may have been among the most heavily exposed. 

“He’s one of the first that went into the residence,” Nieto said. “That’s what we’re thinking — he was the one that got the most of it.”

Lewis was released from UNM Hospital Thursday afternoon and is reported to be doing well according to the Town of Mountainair Facebook page.

Animal quarantine underway

The effects of the mysterious substance have extended beyond humans.

Four dogs that were inside the home are now in quarantine at Mountainair Animal Control, while crews continue searching for a fifth dog.

Staff members are taking significant precautions while caring for the animals.

“We’re wearing all of our PPE just to touch them,” said Jennifer Carter with Mountainair Animal Control. “Right now there are no symptoms. We’re just going to keep an eye on them for the next 10 days.”

So far, all the dogs appear healthy and symptom-free, but officials say they will continue monitoring them closely. If cleared by a veterinarian, the dogs may eventually be put up for adoption unless claimed by family members.

Hospital and community response

At UNM Hospital, dozens of potentially exposed individuals were quarantined as a precaution. While most have now been released, officials say the response is ongoing, with continued monitoring for anyone who may have come into contact with the substance.

The incident has caused fear and uncertainty among those affected — including the quarantined animals.

“They’re grieving, they’re very scared,” Carter said. “They don’t know who I am or the volunteers, so they’re nervous and apprehensive. But we’ll win them over.”

Investigation expands with federal involvement

The case is now being led by New Mexico State Police, with assistance from multiple agencies including Albuquerque Fire Rescue.

FBI agents were seen at the home Wednesday, and officials confirmed that DEA agents conducted air quality testing in and around the property. Authorities have reassured nearby residents that the air is safe.

Key questions remain

With a news conference scheduled for Friday, investigators are expected to provide more clarity. Major questions still remain, including:

• What was the substance that caused the deaths?
• How were 18 first responders exposed?
• Were proper safety protocols followed at the scene?
• What is the current condition of the two remaining patients at UNM Hospital?

Hospital officials are also expected to address their quarantine procedures and safety protocols during the briefing.

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