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Contributor: On autism and vaccines, there are lies, damned lies and statistics

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Contributor: On autism and vaccines, there are lies, damned lies and statistics

During an interview in late April with Dr. Phil, Robert F. Kennedy Jr. reiterated his appeal to parents on vaccine safety: “We live in a democracy, and part of the responsibility of being a parent is to do your own research.”

The U.S. health secretary has also announced his own investigation, pledging to find an answer to the autism “epidemic” by September. It’s an ambitious goal. It’s also a realistic one but only if he already has an answer in mind.

To tell the story you want with statistics, you don’t have to lie or fabricate data — though that happens, too. More often, statistics are manipulated, figures massaged and results skewed through subtler means. Sometimes, it’s sloppiness or unconscious bias at work. Other times, the distortion is deliberate.

Whether the numbers attempt to tell a story about the economy, immigration, education or public health, we should empower ourselves to recognize the deception.

Vaccine data are far from immune to statistical trickery and its consequences.

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Not only might individuals skip a vaccine and get unnecessarily sick, but the viral spread of misinformation can poke holes in the herd immunity needed to protect a population. One new, untampered statistic tells a chilling story: A meager 10% drop from today’s already dangerously low measles vaccination rates could spark an estimated 13-fold increase in annual cases.

Statistics wield incredible power. I developed a deep respect for them during my first career as a biostatistician. Today, as a journalist, I see numbers leveraged for good and for bad. I’ve seen them help the public and policymakers interpret complex data, detect patterns and make better decisions — evidenced in my reporting on data dashboards during the COVID-19 pandemic. I’ve also seen data withheld and statistics doctored for less-than-noble aims by chemical companies, the gun industry, police departments, the U.S. military, climate change deniers and vaccine skeptics, to name a few.

If left unaware of the deceit, the public can’t hold these groups accountable. And if citizens base their votes and other decisions — like whether to vaccinate their child — on distorted or false information, our democracy and our health lose again.

Fortunately, inoculation against misinformation is available. As Kennedy and his collaborators dig into vaccine and autism data, as measles cases mount, and as you “do your own research” or simply digest your news and social feeds, here are five red flags to watch for.

Chance

The infamous paper that launched the vaccine-autism controversy was based on just 12 children. Its author claimed that eight showed signs of developmental regression after receiving the measles-mumps-rubella vaccine. The study was later retracted for scientific misconduct. But even without fraud, the sample size should raise alarm. Chance alone could explain such a small cluster of cases. Contrast that with rigorous studies — like one in Denmark with more than 650,000 participants — that consistently find no relationship between the MMR vaccine and autism.

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We should be just as wary when studies test a grab bag of possible outcomes. Suppose researchers ask whether a vaccine causes heart disease, diabetes, any of a dozen types of cancer or any of five neurodevelopmental disorders. Even if the vaccine is in reality not affecting any of those 20 outcomes, when researchers try to study so many things all at once, statistical noise can mean one may erroneously appear “significant” just by chance. A more rigorous and targeted study would be far less likely to give that false positive.

Count quality

Big numbers can impress. But quality counts. In 2021, the Delphi-Facebook survey estimated near real-time COVID-19 vaccine uptake using weekly responses from around 250,000 people. On paper, the large sample size conveyed statistical confidence. But in practice, the data missed the mark. The sample was biased and unrepresentative of the overall population. By late May, the study had overestimated vaccine uptake by a wide margin — 70% compared with the true rate of 53%. That inflated figure may have lulled the public and policymakers into a false sense of security.

Beware, too, of the misuse of raw data. Figures from the Vaccine Adverse Event Reporting System appear in many papers and posts asserting vaccine harms. But this system was set up only as an early warning system. Anyone can submit a report on a suspected reaction. If a hint of a pattern emerges, then researchers will investigate to determine if the signal represents an actual risk. As its own website warns, the initial reports may be “incomplete, inaccurate, coincidental, or unverifiable.” People may be apt to connect an event that occurs shortly after vaccination with the shot itself, for example, especially if they personally fear the safety of vaccines. To demonstrate the system’s fallibility, a doctor filed a report saying he turned into the Incredible Hulk after receiving a flu vaccine. The entry was initially accepted into the database.

Cherry-picking

One study circulating in the anti-vax community was led by David Geier, the same figure tapped by Kennedy to head his federal autism and vaccine investigation. The study found a connection between autism and vaccines containing the preservative thimerosal. But it hinges on a critical flaw: Cases of autism and the comparison group came from different time periods. Because vaccination rates changed dramatically over time, the design introduced a spurious association.

Among myriad ways to manufacture a desired conclusion is the strategic choice of time frame, analysis method or how the data are presented. By plotting only convenient variables or truncating inconvenient values, for example, you can tell the story of your choosing. One COVID-era graph appeared to show that vaccines did not prevent deaths. The trick? It compared vaccine uptake with cumulative deaths — a number that can only rise over time, and so of course would broadly move in the same direction as the uptake rate of a desperately needed new vaccine that the public is clamoring for.

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Another sleight of hand to play down the size of a problem: Acknowledge a not-so-unusual number of outbreaks while ignoring how large or how deadly those outbreaks were, just as Kennedy did in February with measles.

Correlation vs. causation

A widely shared study recently referenced by Kennedy reports a link between vaccination and neurodevelopmental disorders among 9-year-olds in Florida. This one, too, is riddled with problems — namely, its failure to account for other factors that could explain the results. Children whose parents more regularly use the healthcare system, for example, are more likely to get both vaccinated and diagnosed. Healthcare engagement confounds the relationship. So, we can’t say the vaccine caused neurodevelopmental disorders any more than we could say that increased consumption of margarine resulted in a higher divorce rate in Maine. These are cases of correlation, not causation.

Something similar and even more interesting cropped up when people compared death rates by COVID-19 vaccination status. At first glance, an unexpected pattern emerged: The vaccinated were dying at about twice the rate of the unvaccinated. The catch here? The analysis didn’t account for age. Older people were more likely both to die and to get vaccinated. Once researchers broke the data down into age groups, a more accurate — and reverse — picture emerged: The unvaccinated were dying at higher rates.

Context and conflicts

Talk of an uptick in autism diagnoses often skips crucial context: expanded awareness, broader diagnostic criteria and financial incentives for diagnosis. There could well be a surge in the number of cases without any surge in the true incidence of the disorder.

Also, discussions motivated by a desire to explain autism or to oppose vaccines tend to omit the robust studies that have debunked any link between vaccines and autism — because those would be unhelpful to the agendas. Vaccine opponents may further ignore the glaring conflicts of interest behind many of the studies still pushing that autism narrative. Geier had a study retracted, in part, for not disclosing his involvement in vaccine-related litigation.

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Conflicts of interest surround Kennedy as well. He has spent years pushing anti-vaccine claims despite overwhelming evidence of vaccine safety and despite not being a doctor or a scientist. Now that he is in a position of authority over public health, he should at least be held to the same ethical standards as a scientist. Modern scientific practice calls for statisticians to specify their hypotheses and analysis plans before data are collected. This ensures transparency and objectivity, and reduces the risk of data dredging and misleading results. Statisticians follow where the data lead rather than mold or seek out data to fit a predetermined narrative.

Kennedy’s team appears to be following a different playbook. According to a former top vaccine official, Kennedy’s team requested a wish list of data seemingly to justify their autism theory: The team asked for cases of brain swelling and deaths caused by the measles vaccine. The official said there are no such cases. Someone who keeps hunting for evidence to back up his discredited theory is not conducting science.

Our stories should be malleable. Our statistics should not.

Lynne Peeples, a science writer, is the author of “The Inner Clock: Living in Sync With Our Circadian Rhythms.”

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Commentary: My toothache led to a painful discovery: The dental care system is full of cavities as you age

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Commentary: My toothache led to a painful discovery: The dental care system is full of cavities as you age

I had a nagging toothache recently, and it led to an even more painful revelation.

If you X-rayed the state of oral health care in the United States, particularly for people 65 and older, the picture would be full of cavities.

“It’s probably worse than you can even imagine,” said Elizabeth Mertz, a UC San Francisco professor and Healthforce Center researcher who studies barriers to dental care for seniors.

Mertz once referred to the snaggletoothed, gap-filled oral health care system — which isn’t really a system at all — as “a mess.”

But let me get back to my toothache, while I reach for some painkiller. It had been bothering me for a couple of weeks, so I went to see my dentist, hoping for the best and preparing for the worst, having had two extractions in less than two years.

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Let’s make it a trifecta.

My dentist said a molar needed to be yanked because of a cellular breakdown called resorption, and a periodontist in his office recommended a bone graft and probably an implant. The whole process would take several months and cost roughly the price of a swell vacation.

I’m lucky to have a great dentist and dental coverage through my employer, but as anyone with a private plan knows, dental insurance can barely be called insurance. It’s fine for cleanings and basic preventive routines. But for more complicated and expensive procedures — which multiply as you age — you can be on the hook for half the cost, if you’re covered at all, with annual payout caps in the $1,500 range.

“The No. 1 reason for delayed dental care,” said Mertz, “is out-of-pocket costs.”

So I wondered if cost-wise, it would be better to dump my medical and dental coverage and switch to a Medicare plan that costs extra — Medicare Advantage — but includes dental care options. Almost in unison, my two dentists advised against that because Medicare supplemental plans can be so limited.

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Sorting it all out can be confusing and time-consuming, and nobody warns you in advance that aging itself is a job, the benefits are lousy, and the specialty care you’ll need most — dental, vision, hearing and long-term care — are not covered in the basic package. It’s as if Medicare was designed by pranksters, and we’re paying the price now as the percentage of the 65-and-up population explodes.

So what are people supposed to do as they get older and their teeth get looser?

A retired friend told me that she and her husband don’t have dental insurance because it costs too much and covers too little, and it turns out they’re not alone. By some estimates, half of U.S. residents 65 and older have no dental insurance.

That’s actually not a bad option, said Mertz, given the cost of insurance premiums and co-pays, along with the caps. And even if you’ve got insurance, a lot of dentists don’t accept it because the reimbursements have stagnated as their costs have spiked.

But without insurance, a lot of people simply don’t go to the dentist until they have to, and that can be dangerous.

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“Dental problems are very clearly associated with diabetes,” as well as heart problems and other health issues, said Paul Glassman, associate dean of the California Northstate University dentistry school.

There is one other option, and Mertz referred to it as dental tourism, saying that Mexico and Costa Rica are popular destinations for U.S. residents.

“You can get a week’s vacation and dental work and still come out ahead of what you’d be paying in the U.S.,” she said.

Tijuana dentist Dr. Oscar Ceballos told me that roughly 80% of his patients are from north of the border, and come from as far away as Florida, Wisconsin and Alaska. He has patients in their 80s and 90s who have been returning for years because in the U.S. their insurance was expensive, the coverage was limited and out-of-pocket expenses were unaffordable.

“For example, a dental implant in California is around $3,000-$5,000,” Ceballos said. At his office, depending on the specifics, the same service “is like $1,500 to $2,500.” The cost is lower because personnel, office rent and other overhead costs are cheaper than in the U.S., Ceballos said.

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As we spoke by phone, Ceballos peeked into his waiting room and said three patients were from the U.S. He handed his cellphone to one of them, San Diegan John Lane, who said he’s been going south of the border for nine years.

“The primary reason is the quality of the care,” said Lane, who told me he refers to himself as 39, “with almost 40 years of additional” time on the clock.

Ceballos is “conscientious and he has facilities that are as clean and sterile and as medically up to date as anything you’d find in the U.S.,” said Lane, who had driven his wife down from San Diego for a new crown.

“The cost is 50% less than what it would be in the U.S.,” said Lane, and sometimes the savings is even greater than that.

Come this summer, Lane may be seeing even more Californians in Ceballos’ waiting room.

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“Proposed funding cuts to the Medi-Cal Dental program would have devastating impacts on our state’s most vulnerable residents,” said dentist Robert Hanlon, president of the California Dental Assn.

Dental student Somkene Okwuego smiles after completing her work on patient Jimmy Stewart, 83, who receives affordable dental work at the Ostrow School of Dentistry of USC on the USC campus in Los Angeles on February 26, 2026.

(Genaro Molina / Los Angeles Times)

Under Proposition 56’s tobacco tax in 2016, supplemental reimbursements to dentists have been in place, but those increases could be wiped out under a budget-cutting proposal. Only about 40% of the state’s dentists accept Medi-Cal payments as it is, and Hanlon told me a CDA survey indicates that half would stop accepting Medi-Cal patients and many others will accept fewer patients.

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“It’s appalling that when the cost of providing healthcare is at an all-time high, the state is considering cutting program funding back to 1990s levels,” Hanlon said. “These cuts … will force patients to forgo or delay basic dental care, driving completely preventable emergencies into already overcrowded emergency departments.”

Somkene Okwuego, who as a child in South L.A. was occasionally a patient at USC’s Herman Ostrow School of Dentistry clinic, will graduate from the school in just a few months.

I first wrote about Okwuego three years ago, after she got an undergrad degree in gerontology, and she told me a few days ago that many of her dental patients are elderly and have Medi-Cal or no insurance at all. She has also worked at a Skid Row dental clinic, and plans after graduation to work at a clinic where dental care is free or discounted.

Okwuego said “fixing the smiles” of her patients is a privilege and boosts their self-image, which can help “when they’re trying to get jobs.” When I dropped by to see her Thursday, she was with 83-year-old patient Jimmy Stewart.

Stewart, an Army veteran, told me he had trouble getting dental care at the VA and had gone years without seeing a dentist before a friend recommended the Ostrow clinic. He said he’s had extractions and top-quality restorative care at USC, with the work covered by his Medi-Cal insurance.

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I told Stewart there could be some Medi-Cal cuts in the works this summer.

“I’d be screwed,” he said.

Him and a lot of other people.

steve.lopez@latimes.com

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Diablo Canyon clears last California permit hurdle to keep running

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Diablo Canyon clears last California permit hurdle to keep running

Central Coast Water authorities approved waste discharge permits for Diablo Canyon nuclear plant Thursday, making it nearly certain it will remain running through 2030, and potentially through 2045.

The Pacific Gas & Electric-owned plant was originally supposed to shut down in 2025, but lawmakers extended that deadline by five years in 2022, fearing power shortages if a plant that provides about 9 percent the state’s electricity were to shut off.

In December, Diablo Canyon received a key permit from the California Coastal Commission through an agreement that involved PG&E giving up about 12,000 acres of nearby land for conservation in exchange for the loss of marine life caused by the plant’s operations.

Today’s 6-0 vote by the Central Coast Regional Water Board approved PG&E’s plans to limit discharges of pollutants into the water and continue to run its “once-through cooling system.” The cooling technology flushes ocean water through the plant to absorb heat and discharges it, killing what the Coastal Commission estimated to be two billion fish each year.

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The board also granted the plant a certification under the Clean Water Act, the last state regulatory hurdle the facility needed to clear before the federal Nuclear Regulatory Commission (NRC) is allowed to renew its permit through 2045.

The new regional water board permit made several changes since the last one was issued in 1990. One was a first-time limit on the chemical tributyltin-10, a toxic, internationally-banned compound added to paint to prevent organisms from growing on ship hulls.

Additional changes stemmed from a 2025 Supreme Court ruling that said if pollutant permits like this one impose specific water quality requirements, they must also specify how to meet them.

The plant’s biggest water quality impact is the heated water it discharges into the ocean, and that part of the permit remains unchanged. Radioactive waste from the plant is regulated not by the state but by the NRC.

California state law only allows the plant to remain open to 2030, but some lawmakers and regulators have already expressed interest in another extension given growing electricity demand and the plant’s role in providing carbon-free power to the grid.

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Some board members raised concerns about granting a certification that would allow the NRC to reauthorize the plant’s permits through 2045.

“There’s every reason to think the California entities responsible for making the decision about continuing operation, namely the California [Independent System Operator] and the Energy Commission, all of them are sort of leaning toward continuing to operate this facility,” said boardmember Dominic Roques. “I’d like us to be consistent with state law at least, and imply that we are consistent with ending operation at five years.”

Other board members noted that regulators could revisit the permits in five years or sooner if state and federal laws changes, and the board ultimately approved the permit.

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Deadly bird flu found in California elephant seals for the first time

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Deadly bird flu found in California elephant seals for the first time

The H5N1 bird flu virus that devastated South American elephant seal populations has been confirmed in seals at California’s Año Nuevo State Park, researchers from UC Davis and UC Santa Cruz announced Wednesday.

The virus has ravaged wild, commercial and domestic animals across the globe and was found last week in seven weaned pups. The confirmation came from the U.S. Department of Agriculture’s National Veterinary Services Laboratory in Ames, Iowa.

“This is exceptionally rapid detection of an outbreak in free-ranging marine mammals,” said Professor Christine Johnson, director of the Institute for Pandemic Insights at UC Davis’ Weill School of Veterinary Medicine. “We have most likely identified the very first cases here because of coordinated teams that have been on high alert with active surveillance for this disease for some time.”

Since last week, when researchers began noticing neurological and respoiratory signs of the disease in some animals, 30 seals have died, said Roxanne Beltran, a professor of ecology and evolutionary biology at UC Santa Cruz. Twenty-nine were weaned pups and the other was an adult male. The team has so far confirmed the virus in only seven of the dead pups.

Infected animals often have tremors convulsions, seizures and muscle weakness, Johnson said.

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Beltran said teams from UC Santa Cruz, UC Davis and California State Parks monitor the animals 260 days of the year, “including every day from December 15 to March 1” when the animals typically come ashore to breed, give birth and nurse.

The concerning behavior and deaths were first noticed Feb. 19.

“This is one of the most well-studied elephant seal colonies on the planet,” she said. “We know the seals so well that it’s very obvious to us when something is abnormal. And so my team was out that morning and we observed abnormal behaviors in seals and increased mortality that we had not seen the day before in those exact same locations. So we were very confident that we caught the beginning of this outbreak.”

In late 2022, the virus decimated southern elephant seal populations in South America and several sub-Antarctic Islands. At some colonies in Argentina, 97% of pups died, while on South Georgia Island, researchers reported a 47% decline in breeding females between 2022 and 2024. Researchers believe tens of thousands of animals died.

More than 30,000 sea lions in Peru and Chile died between 2022 and 2024. In Argentina, roughly 1,300 sea lions and fur seals perished.

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At the time, researchers were not sure why northern Pacific populations were not infected, but suspected previous or milder strains of the virus conferred some immunity.

The virus is better known in the U.S. for sweeping through the nation’s dairy herds, where it infected dozens of dairy workers, millions of cows and thousands of wild, feral and domestic mammals. It’s also been found in wild birds and killed millions of commercial chickens, geese and ducks.

Two Americans have died from the virus since 2024, and 71 have been infected. The vast majority were dairy or commercial poultry workers. One death was that of a Louisiana man who had underlying conditions and was believed to have been exposed via backyard poultry or wild birds.

Scientists at UC Santa Cruz and UC Davis increased their surveillance of the elephant seals in Año Nuevo in recent years. The catastrophic effect of the disease prompted worry that it would spread to California elephant seals, said Beltran, whose lab leads UC Santa Cruz’s northern elephant seal research program at Año Nuevo.

Johnson, the UC Davis researcher, said the team has been working with stranding networks across the Pacific region for several years — sampling the tissue of birds, elephant seals and other marine mammals. They have not seen the virus in other California marine mammals. Two previous outbreaks of bird flu in U.S. marine mammals occurred in Maine in 2022 and Washington in 2023, affecting gray and harbor seals.

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The virus in the animals has not yet been fully sequenced, so it’s unclear how the animals were exposed.

“We think the transmission is actually from dead and dying sea birds” living among the sea lions, Johnson said. “But we’ll certainly be investigating if there’s any mammal-to-mammal transmission.”

Genetic sequencing from southern elephant seal populations in Argentina suggested that version of the virus had acquired mutations that allowed it to pass between mammals.

The H5N1 virus was first detected in geese in China in 1996. Since then it has spread across the globe, reaching North America in 2021. The only continent where it has not been detected is Oceania.

Año Nuevo State Park, just north of Santa Cruz, is home to a colony of some 5,000 elephant seals during the winter breeding season. About 1,350 seals were on the beach when the outbreak began. Other large California colonies are located at Piedras Blancas and Point Reyes National Sea Shore. Most of those animals — roughly 900 — are weaned pups.

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It’s “important to keep this in context. So far, avian influenza has affected only a small proportion of the weaned at this time, and there are still thousands of apparently healthy animals in the population,” Beltran said in a press conference.

Public access to the park has been closed and guided elephant seal tours canceled.

Health and wildlife officials urge beachgoers to keep a safe distance from wildlife and keep dogs leashed because the virus is contagious.

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