West Allis Fire demonstrates using Narcan for opioid overdoses
West Allis Fire Department Assistant Chief Armando Suarez Del Real illustrates how a Narcan nasal spray kit is administered in the event of an overdose.
- New data show 387 drug overdose deaths in Milwaukee County in 2025, down about 43% from their peak in 2022.
- County officials credit efforts to increase access to Narcan, addiction treatment and drug testing strips.
- Overdose deaths caused by multiple drugs are still a concern. The combination of cocaine and fentanyl was most prevalent in the county in 2025.
- The county is spending $111 million over the next several years in opioid settlement funds.
The number of Milwaukee County residents who died from a drug overdose fell for a third year in 2025, which county officials say is a promising sign that more money spent on harm reduction, treatment and prevention efforts is working.
New data released April 21 show 387 overdose deaths across the county last year, down about 43% from their peak in 2022.
“The work is paying off,” Dr. Ben Weston, Milwaukee County’s chief health policy adviser, said at a news conference, touting the county’s vending machines stocked with Narcan and drug testing strips, as well as a state-sponsored data collection system that helps local health departments understand when and where overdoses occur.
Still, the hundreds of county residents who lost their lives last year to a drug overdose means that work isn’t close to done, officials say – especially as the drug landscape continues to change, presenting new challenges.
“We can’t let our foot off the gas quite yet,” said Milwaukee County Executive David Crowley.
More: What’s in Wisconsin’s plan for latest round of opioid settlement funds?
Drug mixing continues to drive lethal outcomes
Milwaukee County’s decline in overdose deaths is a trend mirrored across the state and the country, following years of climbing fatalities that were deemed a public health crisis.
The county will spend $111 million in opioid settlement funds over the next several years and is already putting what it has received to use, focusing on “reaching residents where they are,” said Jeremy Triblett, prevention integration manager with the Milwaukee County Department of Health and Human Services.
That includes initiatives like the harm reduction vending machines and also knocking on doors, providing county EMS workers with Narcan and seeking the opinions of people who use drugs to shape the county’s strategy.
But officials say they still see a concerning trend of combinations of drugs leading to overdose, particularly fentanyl being cut with stimulants such as cocaine. These mixes of drugs make it harder to reverse an overdose, said Dr. Wieslawa Tlomak, Milwaukee County’s chief medical examiner.
Nearly a third of all autopsies the medical examiner’s office conducted in 2025 were deaths by drug overdose, Tlomak said, and the majority involved multiple drugs. Data show the most common combinations were fentanyl and cocaine, cocaine and alcohol, and opoids and fentanyl.
Methamphetamines are also involved in more overdose deaths than a few years ago, Tlomak said.
For drug users, not knowing exactly what’s in the drug they are getting is one of the most dangerous elements of the current drug landscape, she said.
More: Wisconsin prisons, jails expand opioid treatment, but gaps remain
Fatal drug overdoses were most common among American Indian and Alaska Native residents in 2025, the data show, followed by Black residents. About two-thirds of fatal overdoses were in men, and the median age of death from an overdose was 49, a number that’s been climbing steadily since 2018.
Triblett said the county is focusing on how substances interact with cultural norms in different communities and that a community advisory board is convening to develop harm reduction messaging for specific populations. His team will also host a door-knocking event June 12 to reach new people across the county with prevention and treatment resources.
Madeline Heim covers health and the environment for the Milwaukee Journal Sentinel. Contact her at 920-996-7266 or mheim@usatodayco.com.
