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Detroit Lions at Arizona Cardinals: Predictions and latest odds for NFL Week 3

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Detroit Lions at Arizona Cardinals: Predictions and latest odds for NFL Week 3


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The Arizona Cardinals will host the Detroit Lions in an NFL Week 3 clash between two teams that have started 1-1 this season.

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For the Lions, the 2024 schedule kicked off well enough, with a win over the Los Angeles Rams in a playoff rematch. However, Detroit didn’t follow it up, falling flat in last week’s loss at home to Tampa Bay. Jared Goff threw for 307 yards, but two costly interceptions set the Buccaneers up for a late game-winning touchdown. In what’s expected to be a high-scoring game, execution in the red zone will be key for the Lions.

Fantasy football Start ‘Em, Sit ‘Em: 50 players to start or sit in Week 3

Arizona, meanwhile, has to be feeling pretty good at the moment. A team largely projected to struggle in the NFC West pushed the Buffalo Bills in Week 1, losing a one-possession game, before clobbering the Rams in California last weekend. Marvin Harrison Jr. (130 yards, two touchdowns) and James Conner (132 total yards, one touchdown) were both superb, but the Cardinals’ defense might end up being the make-or-break factor in this one.

Lions vs. Cardinals odds, moneyline, over/under

Detroit is favored to win this one, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

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  • Spread: Lions (-3)
  • Moneyline: Lions (-150), Cardinals (+125)
  • Over/under: 51.5 points

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Monday Night Football odds.

New to sports betting? USA TODAY readers can claim exclusive promos and bonus codes with the best online sportsbooks and sports betting sites.

NFL Week 3 odds, predictions and picks

Jets vs. Patriots | Browns vs. Giants | Colts vs. Bears | Vikings vs. Texans | Saints vs. Eagles | Steelers vs. Chargers | Buccaneers vs. Broncos | Titans vs. Packers | Raiders vs. Panthers | Seahawks vs. Dolphins | Cardinals vs. Lions | Cowboys vs. Ravens | Rams vs. 49ers | Falcons vs. Chiefs | Bills vs. Jaguars | Bengals vs. Commanders

USA TODAY: Lions 26, Cardinals 24

Tyler Dragon writes: “The Cardinals are a surprise team through two games. Arizona produced 489 total yards in what was Marvin Harrison Jr.’s welcome to the NFL coming out party. Can the Cardinals match Detroit’s physicality? The Lions will try to dominate the line of scrimmage in this one — and it might be too much for a young Cardinals team to handle.”

CBS Sports: Cardinals 31, Lions 29

Pete Prisco writes: “The Lions are out on the road for the first time, while the Cardinals are coming off an impressive home victory over the Rams. Arizona was outstanding on offense with Kyler Murray, which will stress the Lions defense. Look for Arizona to win a shootout that could get each team into the 30s.”

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Sporting News: Cardinals 23, Lions 20

Bill Bender writes: “The Lions must lean on the running game against an improved Cardinals’ defense. The connection between Kyler Murray and Marvin Harrison Jr. is strong, too. This is a tricky game for Detroit, but Aidan Hutchinson – who has 5.5 sacks – will be the X-factor. The Lions are 5-1 ATS as a road favorite since last season.”

Sports Illustrated: Cardinals 38, Lions 35

Iain MacMillan writes: “When it comes to the total, this game seems like a no-brainer of an OVER bet. Both teams have significantly better offenses than defenses and the Lions moved the ball at times last week against the Bucs, but just couldn’t punch the ball into the end zone. If Detroit can fix its red zone issues, this has all the making of an offensive shootout.”



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Detroit, MI

Water main break forces lane closures on Detroit’s east side

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Water main break forces lane closures on Detroit’s east side



A water main break in Detroit Saturday night has forced lane closures on a road on the city’s east side, according to city officials.

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The incident on East Jefferson Avenue near Burns Avenue was reported around 9 p.m. Officials said a 42-inch water main in the area ruptured.

“Crews responded immediately early Sunday morning to shut off the main and to begin preparing for repairs,” Detroit officials said in a news release.

All residents in the area should have service “due to redundancy in the water system,” according to officials. Anyone who doesn’t is asked to call the Detroit Water and Sewerage Department at 313-267-8000. 

As of Sunday afternoon, the city has not issued a boil water advisory and says there are no issues with street flooding. 

Repairs are expected to begin on Monday and officials estimate they will be completed “around the middle of the week.”

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One lane in each direction of East Jefferson Avenue will remain open at and around the area of the break until repairs are done, and bike lanes at the repair location will be closed.

Officials are asking motorists who drive through the area to budget additional time for their commute or seek an alternate route until all lanes reopen.



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Detroit, MI

Missing Detroit 14-year-old last seen walking a dog several days ago

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Missing Detroit 14-year-old last seen walking a dog several days ago


Dajanae Frazier, 14 (Photo: Detroit Police Department)

Detroit Police say 14-year-old Dajanae Frazier has been missing since Tuesday, March 3.

What we know:

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She was last seen leaving her residence to walk a dog in the 19400 block of Biltmore St. She was wearing a pink shirt, black pants and black boots.

Frazier has black hair with red braids and brown eyes. She is between 5 feet 2 inches and 5 feet 7 inches tall, and weighs approximately 100 to 125 pounds.

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Anyone with information is asked to call the Detroit Police Department’s 8th Precinct at 313-596-5840 or Crime Stoppers at 1-800-SPEAKUP.

The Source: Information from the Detroit Police Department was cited for this story.

Missing PersonsDetroitWayne County
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Handgun, credit cards stolen from truck on Detroit’s west side, police say

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Handgun, credit cards stolen from truck on Detroit’s west side, police say



Police in Detroit are asking for the public’s help after they say an individual stole a handgun and credit cards from a truck on the city’s west side last month.

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According to investigators, the suspect, identified as a male of undisclosed age, broke into a GMC Sierra between 3 a.m. and 5 a.m. on the 1400 block of Holden Street on Feb. 15. He stole the gun and a black bag, which contained medications, eyeglasses and the credit cards, officials said.

Police in Detroit are looking for a male suspected of breaking into a truck on Holden Street and stealing items from it on Feb. 15, 2026.

Detroit Police Department


Police said the male then left the scene in a white Chevrolet Tahoe.

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The Detroit Police Department is looking for information about a white Chevrolet Tahoe that the agency believes was used by a male suspected of stealing items from a truck on Feb. 15, 2026.

Detroit Police Department


Anyone who recognizes the male, the Chevrolet or has any information about the incident is asked to call the agency’s 3rd Precinct at 313-596-1340 or Crime Stoppers of Michigan at 1-800-773-2587, or submit a tip here.

This is a developing story.

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