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Widespread habit may raise colorectal cancer risk more than you think

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Widespread habit may raise colorectal cancer risk more than you think

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Colorectal cancer is now officially the leading cause of cancer-related death among men and women 50 and younger, according to research from the American Cancer Society.

While some risk factors — like age, family history and genetics — can’t be controlled, there are some lifestyle behaviors that can increase the chances of the disease.

One of those is drinking alcohol, which has been linked to an increased risk of at least six different types of cancer. 

HIDDEN VIRUS INSIDE GUT BACTERIA LINKED TO DOUBLED COLORECTAL CANCER RISK, STUDY FINDS

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The International Agency for Research on Cancer (IARC) classifies alcoholic beverages as a Group 1 carcinogen, which means there is strong, sufficient evidence that it causes cancer in humans.

Dr. Tereza Cristina Sardinha, chief of colon and rectal surgery services at Catholic Health on Long Island, New York, confirmed that alcohol is a well-known risk factor for all cancers, but particularly those of the gastrointestinal tract.

Drinking alcohol has been linked to an increased risk of at least six different types of cancer.  (iStock)

“The alcohol, or ethanol, will metabolize and break down into acetaldehyde,” she shared with Fox News Digital. “This metabolism of alcohol is very toxic to the DNA of the cell, which over time can lead to the development of cancer.”

Alcohol also changes the microbiome of the gut, which is another strong factor in cancer risk, according to Sardinha.

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Colorectal cancer is now officially the leading cause of cancer-related death among men and women 50 and younger. (iStock)

“The microbiome has a significant effect on many pathogens in the colon and rectum, and diet and alcohol definitely affect the types of bacteria in your gut.”

When the gut’s “first line of defense” is disrupted, it can trigger a series of changes, particularly DNA damage, inflammation and oxidative stress within cells, the doctor said. 

“These processes are closely linked to cancer development, which is why alcohol is considered a carcinogen.”

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The relationship between alcohol and colorectal cancer risk is “dose-dependent,” she said.

“Patients who drink regularly for a long period of time, meaning at least 10 years, will have a lifetime increase in the development of colorectal cancer.”

“The negative impact of spirits (hard liquor) is greater than beer, which is more than wine,” a doctor told Fox News Digital.  (iStock)

Research shows that for those who drink at least two drinks per day — which is considered “moderate consumption,” the doctor said — the lifetime risk of colorectal cancer will increase by at least 25%.

A heavier drinker, consuming more than two drinks a day, will have an exponentially greater risk. 

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COLORECTAL CANCER NOW DEADLIEST TYPE FOR CERTAIN GROUP OF AMERICANS, STUDY FINDS

“What really makes the difference is not only the volume but the frequency,” Sardinha said. “I just saw one of my patients who I operated on last week, and she drinks six beers a day, and she developed colon cancer. She’s not morbidly obese, she’s not a smoker. The only risk factor she has is alcohol.”

The doctor advises her patients to avoid alcohol “or at least minimize intake.”

“What really makes the difference is not only the volume but the frequency.”

If someone stops drinking, the risk won’t disappear immediately, the doctor noted.

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“It takes about an average of 10 years to know if cancer risk decreased or not,” she said. “But we do know that if you continue drinking, your risk will definitely increase.

MOM WITH NO SYMPTOMS HAD STAGE 4 COLORECTAL CANCER — AND A RARE SURGERY SAVED HER LIFE

“That’s why we recommend that patients stop drinking or exponentially decrease their intake in the same way we tell them to exercise and increase fruits and vegetables in their diet.”

Sardinha pointed out that alcohol isn’t the only culprit. 

“Not all heavy drinkers develop cancer, so there has to be some other mechanism that plays a role,” she said.

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And not all types of alcohol are equal in terms of colorectal cancer risk, according to Dr. Nathan Goodyear, integrative medicine physician at Williams Cancer Institute in California.

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“The negative impact of spirits (hard liquor) is greater than beer, which is more than wine,” he told Fox News Digital. 

A Danish study also found that wine consumption was associated with a lower risk of death, while beer and spirits were not, Goodyear pointed out. Spirits had the highest risk, especially at three to five drinks per day. 

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“The effects of wine, beer and spirits were independent of each other,” the doctor said. 

The context in which alcohol is consumed can also play a role, he noted.

In addition to stopping or limiting alcohol intake, doctors say other healthy lifestyle behaviors, like exercise, have been shown to decrease the chances of colorectal cancer. (iStock)

“In the U.S., alcohol is often used in the context of addiction — another hit to keep the high,” Goodyear said. “But in some communities, such as Sardina, Italy, and Ikaria, Greece, wine is part of the culture, social connections and community.”

“Wine is taken outside the context of addiction and taken within the context of a plant-based diet, social settings, daily movement, faith, community and life.”

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Other ways to minimize risk

In addition to stopping or limiting alcohol intake, Sardinha shared other healthy lifestyle behaviors that have been shown to decrease the chances of colorectal cancer.

One “huge and well-established” factor is regular exercise, she said.

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“If you don’t exercise, if you don’t move, you definitely increase your risk of colorectal cancer,” she told Fox News Digital. “Even for patients who have been diagnosed with cancer, once they have surgery and are able to exercise, that will improve their long-term prognosis.”

Smoking is another highly carcinogenic habit, and it’s a common myth that it’s only associated with lung cancer.

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“We do know that if you continue drinking, your risk will definitely increase.”

“Smoking is a risk factor for most cancers, and colorectal cancer is one of them,” Sardinha said.  

Taking steps to address and prevent obesity is also a well-established way to minimize risk, as is adopting a healthy, high-fiber diet to promote proper bowel function, according to the doctor.

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“Diets that are lower in fiber are often more constipating, and, therefore, if there’s anything in the food that is carcinogenic, that is going to have more direct, prolonged contact with the bowel wall, with the cells, and increases the chances of DNA damage,” she said.

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“Obviously, we cannot change our family history, but those good lifestyle habits will make a difference in the risk of colorectal cancer.”

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.

That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.

The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.

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Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).

Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.

The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.

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“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”

Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.

HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS

In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.

For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)

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The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.

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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”

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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.

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Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)

“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.

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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.

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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs


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What Is Zepbound? Weight-Loss Benefits, Costs and Dosage




















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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION

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Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

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The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

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New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities. 

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment. 

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

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