Health
Tongue cancer warning signs highlighted after ‘Full House’ star’s diagnosis
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On the heels of comedian Dave Coulier’s announcement of his tongue cancer diagnosis, experts are sharing what to know about the disease.
Coulier, 66, announced in a Tuesday interview that he has been diagnosed with early-stage P16 carcinoma, or oropharyngeal tongue cancer.
“Oropharyngeal” refers to cancer that begins at the base of the tongue. The “P16” indicates that it is associated with HPV (human papillomavirus).
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The news comes just months after the “Full House” star announced his battle with an aggressive form of non-Hodgkin Lymphoma. The tongue cancer is “totally unrelated” to that initial cancer, he told “Today” in the interview.
“I went in for a PET scan, just a routine check-up, and something flared on the PET scan,” Coulier said. “It turned out that I have P16 squamous carcinoma at the base of my tongue.”
Dave Coulier, 66, announced in a Tuesday interview that he has been diagnosed with early-stage P16 carcinoma, or oropharyngeal tongue cancer. (Getty Images)
The comedian had announced on April 1 that he was cancer-free following the non-Hodgkin Lymphoma diagnosis.
“To go through chemotherapy and feel that relief of whoah, it’s gone, and then to get a test that says, well now you’ve got another kind of cancer … it is a shock to the system,” he said.
Coulier shared that he will undergo a course of 35 radiation treatments.
What to know about tongue cancer
Tongue cancer can affect the front of the tongue (oral cavity) or the base/back of the tongue (oropharynx), according to the National Cancer Institute. Risk factors and prognosis can differ substantially depending on the location of the cancer.
In 2025, it is expected that there will be about 20,040 new cases of tongue cancer and approximately 3,270 deaths, the NCI states. (These numbers only include cancers that begin in the front two-thirds of the tongue.)
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When including all oral cavity and oropharyngeal cancers — which totals all mouth and throat cancers — the numbers rise to 59,660 new cases and about 12,770 deaths in 2025, per the American Cancer Society.
The overall five-year survival rate for tongue cancer is 71%.
The news comes just months after the “Full House” star, pictured with co-star John Stamos (left), announced his battle with an aggressive form of non-Hodgkin Lymphoma. (Getty Images)
Studies have shown that cases have been on the rise in the U.S. in recent years, affecting almost all age groups and races.
“The rise is linked to the dramatic rise of HPV,” Fox News senior medical analyst Dr. Marc Siegel told Fox News Digital. “It can metastasize, but the prognosis is 80% to 90% curable if it’s HPV-related.”
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George Semeniuk, M.D., a medical oncologist and hematologist at City of Hope in Newport Beach, California, agreed that tongue cancer is one of the fastest-rising head and neck cancers doctors are seeing.
“Early detection is critical,” he told Fox News Digital.
Warning signs and risk factors
Some of the earliest warning signs of tongue cancer include a persistent sore or ulcer on the tongue, pain when swallowing, a lump or changes in speech, according to Semeniuk.
“Anything that lasts longer than two weeks should be evaluated by a specialist,” he advised.
Some of the earliest warning signs of tongue cancer include a persistent sore or ulcer on the tongue, pain when swallowing, a lump in the throat or changes in speech. (iStock)
Siegel added, “Look out for a sore that won’t heal or difficulty swallowing. Show your doctor, ENT or dentist.”
Other common signs include a lump or thickening on the tongue; red or white patches on the tongue or lining of the mouth; persistent tongue, pain in the mouth, jaw or throat; and numbness or burning in the tongue, according to multiple health sources.
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Those affected may also notice difficulty chewing, swallowing or speaking, or unexpected bleeding in the area.
If the cancer has spread, the patient may notice a lump in the neck (from enlarged lymph nodes), ear pain (usually on one side), or stiffness or swelling of the jaw.
The standard treatment for tongue cancer is largely dependent on the stage of the disease and where it is located. (iStock)
The biggest risk factors for tongue cancer are tobacco use, heavy alcohol consumption and HPV, Semeniuk noted.
“We are also seeing increasing cases in younger adults who have never smoked, which underscores the role HPV can play,” he said. “People with long-standing mouth irritation, weakened immune systems or poor oral hygiene may also be at higher risk.”
Treatment and prognosis
The standard treatment for tongue cancer is largely dependent on the stage of the disease and where it is located, according to experts.
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“Treatment depends on the stage and location of the tumor, but often involves a combination of surgery, radiation therapy and, in more advanced cases, chemotherapy or targeted therapies,” Semeniuk said.
“At City of Hope, we also use minimally invasive surgical approaches and precision-guided therapies to preserve speech and swallowing whenever possible.”
Coulier shared that he will undergo a course of 35 radiation treatments. (Getty Images)
Siegel noted that tongue cancer tumors tend to be more responsive to surgical resection, radiation and chemotherapy.
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“Prognosis is significantly better when tongue cancer is diagnosed early. If detected at an early stage, cure rates can be quite high,” Semeniuk told Fox News Digital.
“That’s why it’s so important for people to pay attention to changes in their mouth and seek care promptly. Regular dental visits and HPV vaccination are also important steps in lowering risk.”
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For many, surviving cancer comes with an automatic new lease on life but other survivors continue to experience physical and emotional challenges long after treatment ends.
Yoga may significantly reduce the insomnia, fatigue and mood disturbances many survivors endure after remission, a recent clinical trial found.
Mood disturbance and insomnia are “two of the most pervasive and troubling side effects experienced by cancer survivors for years after completing adjuvant treatments,” the researchers reported in the Journal of Clinical Oncology.
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They noted that both symptoms can substantially inhibit survivors’ ability to perform everyday activities.
The study, funded by the National Cancer Institute, compared 204 cancer survivors receiving standard survivorship care alone with 206 survivors who paired standard care with the Yoga for Cancer Survivors (YOCAS) program. Most of the participants were female breast-cancer survivors.
A clinical trial showed that yoga may help ease symptoms cancer survivors experience after treatments. (iStock)
YOCAS is a four-week intervention that incorporates two types of yoga – hatha, which is traditional and more active, and restorative, which is more passive. Both forms involve slow, gentle movements, breathing exercises and mindfulness, according to the American Society of Clinical Oncology (ASCO), which published a news release on the study’s findings.
Participants in the YOCAS group practiced yoga, on average, for 180 minutes each week over the course of three sessions.
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At the end of the trial, the YOCAS participants reported overall improvements to mood, anxiety and fatigue, while the standard care group did not.
“Additionally, improvements in insomnia stemming from YOCAS yoga may be mediated by changes in overall [mood disturbance] and fatigue,” the researchers wrote.
“[The study is] an important advance because it offers survivors, who are likely already managing multiple medications, a non-pharmaceutical solution for reducing four different side effects at once,” Fumiko Chino, MD, a cancer researcher and associate professor in breast radiation oncology at MD Anderson Cancer Center, told ASCO.
Cancer survivors often continue to struggle with physical and mental-health challenges after the disease has been successfully treated. (iStock)
Timothy Pearman, Ph.D., director of supportive oncology at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, told Fox News Digital he was not surprised by the results of the study.
“Yoga is one of the most widely studied and validated interventions for managing cancer-related fatigue, mood disturbance and overall physical health,” Pearman said.
Pearman said his wife, Jenny Finkel, is a yoga teacher and received her continuing education at Duke University’s integrative medicine program, which focuses on yoga for cancer patients.
“There are now a number of cancer-specific yoga teacher training programs nationwide,” Pearman said. “Yoga is a wonderful thing because it is very modifiable, meaning that even for people who have significant physical impairment, the exercises can be modified so that anyone can participate.”
He added that yoga is affordable, too, because “all you need is a mat and someone to show you how to do it.”
Osteoporosis, an increased risk of cardiac problems and issues with balance and stamina are other physical symptoms related to cancer treatment that yoga can help mitigate, Pearman said.
Cancer survivors who took part in an average of three yoga classes a week for four weeks reported reduced anxiety and fatigue, according to a recent study. (iStock)
Shari Botwin, a licensed clinical social worker based in Pennsylvania, is a thyroid-cancer survivor who specializes in working with victims of trauma, including cancer. She turned to yoga months after her diagnosis and told Fox News Digital the practice has been “transformative.”
According to Botwin, cancer survivors she’s worked with have dealt with emotional challenges that affect their healing process, including depression and survivor’s guilt. In addition to the physical relief yoga can provide, she said it can also offer “a supportive environment of peers, some of which are cancer thrivers.”
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Botwin added that yoga can help survivors who have lost parts of their body reframe their thinking.
“It supports us into moving into a place of self-compassion rather than shame and self-hatred,” she said.
Yoga can help cancer survivors who struggle with guilt or shame to find a community of understanding peers, according to some experts. (iStock)
Almost any type of exercise can be beneficial for cancer survivors, Pearman said. He advises his patients to stick to the type of exercise they enjoyed prior to cancer.
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He also noted that free yoga classes geared toward cancer survivors are widely available through various non-profit organizations.
Jill Biden says Joe’s debate performance made her wonder if he had a stroke
Former first lady Jill Biden revises her account of former President Joe Biden’s disastrous 2024 debate, now alleging she feared he was suffering a stroke. This new statement from the first lady contrasts sharply with her earlier public affirmations of his performance. Contributor Ben Domenech scrutinizes the timing and motivations behind this sudden shift.
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Former first lady Jill Biden has expressed her concerns about former President Joe Biden’s health status, noting that she feared he was having a stroke during a 2024 debate against President Donald Trump.
Biden struggled his way through the performance, with long periods of silence, confused facial expressions and stammered speech. In a recent interview with CBS, Jill Biden commented that she was “frightened.”
“I don’t know what happened,” she said. “I mean, when I watched it, I thought, ‘Oh my God, he’s having a stroke,’ and it scared me to death.”
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A stroke occurs when there is bleeding in the brain or when blood flow to the brain is blocked, according to Mayo Clinic.
Identifying a stroke may be difficult, as symptoms can vary.
Stroke symptoms can include balance loss, weakness, slurred speech, face drooping, confusion and severe headaches. (iStock)
The American Stroke Association (ASA) identifies the following key warning signs, using the acronym “B.E. F.A.S.T.”
- B – Balance loss
- E – Eye (vision) changes
- F – Face drooping
- A – Arm weakness
- S – Speech difficulty
- T – Time to call 911
In a situation in which someone could be having a stroke, “the only” thing to do is to call 911, Fox News senior medical analyst Dr. Marc Siegel told Fox News Digital.
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The doctor emphasized other symptoms to watch for, including weakness on one side, slurred speech, difficulty processing information and confusion.
The ASA also warns that severe headaches can also be a sign of stroke.
At the first sign of stroke, 911 should be contacted immediately, as 1.9 million brain cells die every minute that a stroke goes untreated. (iStock)
Siegel advised against giving the person an aspirin, as it could worsen bleeding in the brain if that is the cause of stroke.
With an ischemic stroke, that type of medication could be helpful.
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The ASA says 1.9 million brain cells die every minute that a stroke goes untreated, which means earlier treatment leads to higher survival rates and lower risk of disability.
“In medicine, we use the term ‘time is brain,’” Siegel said. “This means that the faster you bring the patient to the emergency room, the faster they can receive emergency treatment if indicated to reopen the blocked artery in the brain, if there is one.”
Brain imaging should be done within the first several hours after seeking medical attention for a stroke, according to a top physician. (iStock)
Brain imaging can also be done on arrival at the ER, which should occur within the first several hours, Siegel said.
Anyone who is experiencing a stroke should not drive themselves to the hospital, according to the CDC. Instead, the person should get a ride or call 911 — as treatment begins inside the ambulance.
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About 80% of strokes are preventable, the American Heart Association states.
Prevention includes managing high blood pressure, diabetes, atrial fibrillation and other risk factors.
One in four survivors have another stroke within the next five years, per CDC data, so those at higher risk should prepare a prevention and treatment plan.
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Fox News Digital’s Alexander Hall contributed to this report.
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