As smoke from wildfires crosses state and international borders more frequently, tracking and studying it is increasingly important for shaping air quality and health measures around the world.

An upcoming study from researchers at Stanford University offers a new way to trace far-flung smoke and pollution back to individual wildfires of origin.

What’s burning in a wildfire determines what kind of pollution is in the smoke. A forest fire burns differently from a fire in a swamp, or a fire that burns buildings. As smoke travels, its chemical composition may change with time and distance.

The findings could help officials to determine which wildfires are likely to have the biggest health consequences for the greatest number of people, and to allocate firefighting resources accordingly.

“We don’t find that fire suppression resources are often spent on the fires that are most damaging from a health perspective,” said Jeff Wen, a Ph.D. candidate in Earth system science at Stanford and the study’s lead author.

Others have done similar research before, but at a much smaller scale. The new study, not yet peer reviewed, would be the first to cover the whole contiguous United States, according to the authors.

“Historically, we haven’t really been able to study those types of questions at a broad spatial, temporal scale,” Mr. Wen said.

It’s clear that wildfires have become more frequent and intense in recent years, fueled in part by climate change’s role in drying out many landscapes. Less clear to scientists has been how smoke from these fires has changed over time. The new study shows that as fires have worsened, so has their smoke: From 2016 to 2020, the U.S. population experienced double the smoke pollution that it did 10 years earlier, from 2006 to 2010. While the study focused on historical data, some of its methods can also be used to predict where smoke from a new fire will travel.

The researchers focused on a pollutant called particulate matter, made of very small solid particles floating in the air, which can enter people’s lungs and blood and lead to problems such as difficulty breathing, inflammation and damaged immune cells.

Using their new method, Mr. Wen and his team ranked all of the wildfires observed in the United States from April 2006 to December 2020 by the resulting smoke exposure. They found that the worst fire by smoke exposure during this period was the 2007 Bugaboo Fire, which burned more than 130,000 acres in and around the Okefenokee Swamp, straddling Georgia and Florida.

This initially surprised the researchers, since Western states tend to have more large fires. But the Eastern Seaboard is more densely populated, so smoke from the Bugaboo Fire didn’t have to go far to affect many millions of people. Peatlands like the Okefenokee Swamp also tend to burn slowly, Mr. Wen said, releasing more particulate matter into the air.

The worst fires in their ranking did not match up very well with the worst fires in traditional rankings, such as acres burned or buildings and infrastructure lost. More firefighting resources were not necessarily deployed to the smokiest fires, either.

“We often suppress fires mainly because of structures and immediate threat to life,” said Bonne Ford, an atmospheric scientist at Colorado State University who was not involved in this study. While it’s important to save lives and help rural communities in immediate harm’s way, it’s “short-term thinking” to focus only on those immediately dangerous fires and ignore others that may harm many people farther away through smoke exposure.

Dr. Ford and others have studied wildfire smoke patterns, as well as the resulting exposure to particulate matter pollution. But the Stanford researchers have pulled off something new by putting the two together, she said, especially over so many years and so much land area.

One aspect of the study Dr. Ford took issue with was treating all human exposure to particulate matter in smoke the same, no matter where it happened. Some people are more vulnerable to air pollution, she said, depending on their age, pre-existing health conditions, other environmental factors and whether they can take precautions such as wearing face masks outside and using air filters inside. Future research could combine Mr. Wen’s methods with existing vulnerability indexes, Dr. Ford said.

There are also more precise ways to track and predict where smoke travels, according to John Lin, an atmospheric scientist at the University of Utah who was not involved in the study. Aside from that, Dr. Lin thought the Stanford study would be very useful in figuring out the real human toll of wildfire smoke.

Smoke traveling long distances is “the new normal,” he said. This reality challenges the ways governments have historically dealt with air quality, through regulations like the Clean Air Act. Now that pollution is increasingly crossing borders, Dr. Lin said, the way that people manage air quality should evolve accordingly.