Health
Presidential depression and Abraham Lincoln’s struggle with ‘melancholy’: What historians know
He is perhaps best known for his honesty — but a lesser-known fact about Abraham Lincoln is that the 16th president of the United States battled severe depression during his lifetime.
Dr. Chris Tuell, a clinical psychotherapist and a chemical and behavioral addiction specialist at the University of Cincinnati College of Medicine, has studied Lincoln’s mental health struggles extensively.
“Though the history books play a significant role in our perception and understanding of the ‘rail splitter’ from Illinois, it often becomes easy for us to forget that Abraham Lincoln was very human,” Tuell told Fox News Digital.
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“Lincoln led this nation through its worst crisis, while at the same time battling his own internal war of chronic depression.”
Here’s what to know.
Abraham Lincoln, 16th president of the United States, is depicted in this painting at the Gettysburg Address. (Painting by J.L.G. Ferris)
Signs of Lincoln’s depression
At age 32, in a letter to John Stuart in 1841, Lincoln wrote, “I am now the most miserable man living. If what I feel were equally distributed to the whole human family, there would not be one cheerful face on earth. Whether I shall ever be better, I cannot tell; I awfully forebode I shall not; to remain as I am is impossible.”
Lincoln scholars have “clear evidence” that he suffered from depressive episodes beginning in his 20s, Tuell noted.
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“Lincoln’s school teacher, Mentor Graham, stated, ‘Lincoln told me that he felt like committing suicide often,’” Tuell said.
“Law partner and biographer William Herndon stated, ‘He was a sad-looking man, gloomy and melancholic. His melancholy dripped from him as he walked.’”
Contributing factors to Lincoln’s depression
The president’s mental health condition can be attributed to both genetics and traumatic experiences, according to the book “Lincoln’s Melancholy” by Joshua Wolf Shenk.
Lincoln is said to have had a family history of depression.
Abraham Lincoln, 16th president of the U.S., battled severe depression. (Library of Congress Prints and Photographs)
“Historical records indicate that Lincoln’s mother and father were disposed to melancholy and that one side of the family ‘was thick with mental disease,’” said Tuell.
“Bereavement in childhood can be one of the most significant factors in the development of depressive illness in later life.”
As a child, Lincoln lost several close family members.
After his brother died in infancy, Lincoln’s mother, aunt and uncle all died when he was just 9 years old. A decade later, his sister died while delivering a stillborn infant.
Later, Lincoln experienced the loss of his first love, Ann Rutledge, in 1835.
As a father, he experienced the death of two young sons, Eddie and Willie.
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“According to mental health professionals, bereavement in childhood can be one of the most significant factors in the development of depressive illness in later life,” Tuell said.
Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, said that Lincoln’s melancholy may have been tied to his “intellectual prowess and [his tendency to] see and feel things deeply.”
How Lincoln dealt with depression
Before the age of psychotherapy and antidepressant medications, Lincoln learned to live with his depressive disposition, Tuell said.
“He would frequently use humor and storytelling to elevate his mood and distract himself from his depression,” the psychologist told Fox News Digital.
Abraham Lincoln is depicted at the signing of the Emancipation Proclamation, which gave enslaved people their freedom. (Hulton Archive/Getty Images)
“Only his closest friends had any insight concerning the extent of his condition.”
In a time period when mental health treatment was not available, Tuell noted that learning how to manage his life with his depression was Lincoln’s only choice.
“The only other option would have been for him to succumb to these adversities,” he said.
“He managed to overcome it and the Civil War to become our greatest president, by most people’s estimation.”
“It does not appear that it was in the 16th president’s persona to acquiesce. Lincoln persevered and served this country eloquently.”
Siegel noted that in Lincoln’s time, depression was referred to as “melancholy” and was typically treated with opium, a highly addictive narcotic drug that is extracted from the poppy plant.
“It does not appear that it was in the 16th president’s persona to acquiesce,” a psychologist said. “Lincoln persevered and served this country eloquently.” (AP)
Historians have noted that Lincoln’s sons brought him periods of happiness despite his ongoing depression.
“We are so used to seeing Abraham Lincoln looking depressed and sad, that we forget — and the historical record is clear on this — he would break down in laughter when playing with his boys or observing the mayhem they created,” Raymond Arroyo, a Fox News contributor and bestselling author, previously told Fox News Digital.
He is the author of the book, “The Magnificent Mischief of Tad Lincoln,” part of his Turnabout Tales series of books.
What to know about depression
Depressive disorders affect approximately 18.8 million American adults or about 9.5% of the U.S. population age 18 and older in a given year, according to the National Institute of Mental Health.
There are different types of depressive disorders, according to Tuell.
These may include major depression, dysthymia (an ongoing, low-grade depression) and bipolar (mood swings of depression and mania).
Depressive disorders affect approximately 18.8 million American adults or about 9.5% of the U.S. population age 18 and older in a given year, according to the National Institute of Mental Health. (iStock)
“Depression can affect every aspect of one’s life — physical health, sleep [habits], eating habits, job and your relationships with friends and family,” said Tuell. “It affects thoughts, feelings and behaviors.”
While depression is one of the most serious mental health issues facing people today, Tuell noted that it’s also one of the most treatable.
Lincoln’s perseverance in the face of severe depression was something to be admired, Tuell and Siegel agreed.
“We can only speculate what Lincoln would say or do about our current state of political affairs, or even what thoughts he may have toward the new millennium’s understanding of depression and mental health,” Tuell said.
President Abraham Lincoln with General George B. McClellan at his headquarters at Antietam, Oct. 3, 1862. From left: General George W. Morell, Colonel Alexander S. Webb, General McClellan, scout Adams, Dr. Jonathan Letterman, unidentified officer, President Lincoln, Colonel Henry Hunt, General Fitz, John Porter, unidentified officer. (Getty Images)
“But now, some 159 years later, Lincoln’s historical persona continues to belong to the ages.”
Lincoln believed in the human spirit and spoke of the role people must have toward one another, Tuell noted.
“This was no more clearly expressed than through Lincoln’s own words, ‘With malice toward none; with charity for all,’” he said.
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Lincoln’s battle with depression can be regarded as an “inspiration to all who suffer from this dreaded disease or feel stigmatized by it,” Siegel added.
“He managed to overcome it and the Civil War to become our greatest president, by most people’s estimation.”
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Collagen supplements have exploded in popularity, touted as everything from an anti-aging miracle to a muscle recovery booster.
But a sweeping new review conducted by U.K. researchers suggests that while collagen may help improve skin elasticity and ease arthritis pain, it does little for athletic performance or wrinkle reduction.
Researchers from Anglia Ruskin University analyzed 16 systematic reviews and 113 randomized controlled trials involving nearly 8,000 participants worldwide, which they say is the most extensive evaluation of collagen’s health effects to date.
The review found consistent evidence that collagen supplementation improves skin elasticity and hydration over time and provides significant relief from osteoarthritis-related joint pain and stiffness, according to findings published in Aesthetic Surgery Journal Open Forum.
A large U.K. review found that collagen supplements may improve skin elasticity and hydration over time. (iStock)
The researchers, however, did not find meaningful improvements in post-exercise muscle recovery, soreness or tendon mechanical properties (strength, springiness and stretch resistance).
“Collagen is not a cure-all, but it does have credible benefits when used consistently over time, particularly for skin and osteoarthritis,” co-author Lee Smith, professor of public health at Anglia Ruskin University, said in a statement.
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“Our findings show clear benefits in key areas of healthy aging, while also dispelling some of the myths surrounding its use,” Smith added.
Collagen, the most abundant protein in the body, supports skin, bones, tendons, cartilage and connective tissue, according to experts. Natural collagen production begins to drop in early adulthood and declines more sharply with age.
The study found that collagen supplements may help reduce joint pain and stiffness in people with osteoarthritis. (iStock)
The review found that long-term collagen supplementation was linked to improved skin firmness and hydration, but did not help skin roughness — a proxy for visible wrinkles.
Benefits appear to accumulate gradually, suggesting that collagen should not be viewed as an “anti-wrinkle ‘quick fix,’ but as a foundational dermal support for individuals seeking holistic skin maintenance,” the researchers said.
“If we define anti-aging as a product or technique designed to prevent the appearance of getting older, then I believe our findings do support this claim for some parameters,” Smith told the BBC. “For example, an improvement in skin tone and moisture is associated with a more youthful-looking appearance.”
Collagen supplementation was linked to reduced pain and stiffness in people with osteoarthritis, with stronger benefits seen over longer periods of use, and showed modest improvements in muscle mass and tendon structure that may support healthy aging.
Collagen did not significantly improve skin roughness, a marker of visible wrinkles. (iStock)
However, it did not show meaningful results when used as a fast-acting sports performance supplement, and evidence for benefits related to cholesterol, blood sugar, blood pressure and oral health was mixed or inconclusive.
Dr. Daniel Ghiyam, a California-based physician and longevity specialist, said the findings align with what he sees in clinical practice.
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“Collagen is a targeted support tool, not a foundation of health or performance,” Ghiyam, who was not involved in the study, told Fox News Digital. “When marketed that way, it makes sense. When marketed as a cure-all, it doesn’t hold up to the data.”
The authors noted that while many previous collagen studies have received financial support from the supplement industry, the current review did not receive industry funding.
Experts say collagen supplements may offer modest benefits for skin hydration and joint comfort, but they are not a cure-all. (iStock)
The team called for more high-quality clinical trials examining long-term outcomes, optimal dosages and differences between collagen sources, such as marine, bovine and plant-based alternatives.
Among its limitations, the review could not determine whether certain forms of collagen work better than others or what the optimal regimen should be.
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While the review included randomized controlled trials, the quality of the studies varied, with newer research generally showing stronger results.
Experts say more data and studies are needed to build on the findings. They also noted that diet plays a crucial role in skin health.
Collagen supplements, often sold as powders or pills, may improve skin elasticity and ease joint pain, experts say. (iStock)
Dr. Erum Ilyas, a Pennsylvania-based dermatologist and chair of dermatology at Drexel University College of Medicine, noted that the review analyzed previously published meta-analyses rather than generating new primary data.
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“At this time, I have not seen sufficiently strong independent evidence to routinely recommend collagen supplements to my patients,” Ilyas, who was not involved in the review, told Fox News Digital.
“Although some studies show modest improvements in markers such as hydration and elasticity, there remains limited independent, biopsy-confirmed evidence demonstrating sustained increases in dermal collagen content,” she added.
Fox News Digital has reached out to the researchers for comment.
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As colorectal cancer (CRC) is now the leading cause of cancer death in adults under 50, a new report reveals some surprising shifts in the incidence of the disease.
Although rates of CRC have been declining among seniors, those 65 and under are facing a rise in diagnoses, according to a report titled Colorectal Cancer Statistics, 2026, from the American Cancer Society.
Adults 65 and younger comprise nearly half (45%) of all new colorectal cancer cases — a significant increase from 27% in 1995, states the report, which was published in CA: A Cancer Journal for Clinicians.
The disease is rising fastest among adults 20 to 49 years old, at a rate of 3% per year.
Colorectal cancer is now the leading cause of cancer death in adults under 50. (iStock)
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. Although that age group is eligible to receive routine screenings, just 37% do so.
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The report also revealed that rectal cancer is on the rise, now accounting for about one-third (32%) of all CRC cases — an increase from 27% in the mid-2000s.
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“After decades of progress, the risk of dying from colorectal cancer is climbing in younger generations of men and women, confirming a real uptick in disease because of something we’re doing or some other exposure,” said Rebecca Siegel, senior scientific director, surveillance research at the American Cancer Society and lead author of the report, in a press release.
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. (iStock)
“We need to redouble research efforts to understand the cause, but also circumvent deaths through earlier detection by educating clinicians and the general public about symptoms and increasing screening in people 45-54 years.”
It is projected that 158,850 new cases of colorectal cancer will be diagnosed this year, and that the disease will cause 55,230 deaths, per the report.
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More than half of CRC cases can be linked to high-risk behaviors, the researchers said. Those include lack of nutrition, high alcohol consumption, smoking, lack of exercise and obesity.
“These findings further underscore that colorectal cancer is worsening among younger generations and highlight the immediate need for eligible adults to begin screening at the recommended age of 45,” said Dr. William Dahut, chief scientific officer at the American Cancer Society.
When the disease is caught at a local (early) stage, the five-year survival rate is 95%. (iStock)
“The report also shines a light on the crucial importance of continued funding for research to help discover new therapies to treat the disease and advance patient care.”
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When the disease is caught at a local (early) stage, the five-year survival rate is 95%, the report stated.
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A new study suggests that middle-aged men may be more vulnerable to faster biological aging, potentially linked to exposure to “forever chemicals.”
The research, published in the journal Frontiers in Aging, examined how perfluoroalkyl and polyfluoroalkyl substances, more commonly known as PFAS, could impact aging at the cellular level.
PFAS are synthetic chemicals commonly used in nonstick cookware, food packaging, water-resistant fabrics and other consumer products, the study noted.
Their chemical structure makes them highly resistant to breaking down, allowing them to accumulate in water, soil and the human body.
Chinese researchers analyzed blood samples from 326 adults enrolled in the U.S. National Health and Nutrition Examination Survey between 1999 and 2000.
A new study suggests that middle-aged men could face accelerated biological aging at the cellular level due to exposure to PFAS. (iStock)
The researchers measured levels of 11 PFAS compounds in participants’ blood and used DNA-based “epigenetic clocks” — tools that analyze chemical changes to DNA to estimate biological age — to determine how quickly their bodies were aging at the cellular level, the study stated.
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Two compounds, perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA), were detected in 95% of participants.
Higher concentrations of those chemicals were associated with faster biological aging in men of certain age groups, but not in women.
“People should not panic.”
The compounds most strongly linked to accelerated aging were not the PFAS chemicals that typically receive the most public attention, the researchers noted.
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“The associations were strongest in adults aged 50 to 64, particularly in men,” Dr. Xiangwei Li, professor at Shanghai Jiao Tong University School of Medicine and the study’s corresponding author, told Fox News Digital.
“While this does not establish that PFAS cause aging, it suggests that these widely present ‘forever chemicals’ may be linked to molecular changes related to long-term health and aging.”
The study found that two of the compounds were detected in 95% of participants, and higher levels were linked to faster biological aging in men ages 50–64. (iStock)
Midlife may represent a more sensitive biological period, when the body becomes more vulnerable to age-related stressors, according to the researchers.
Lifestyle factors, such as smoking, may influence biological aging markers, potentially increasing vulnerability to environmental pollutants.
While Li said “people should not panic,” she does recommend looking for reasonable ways to reduce exposure.
That might mean checking local drinking water reports, using certified water filters designed to reduce PFAS, and limiting the use of stain- or grease-resistant products when alternatives are available.
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Meaningful reductions in PFAS exposure will likely depend on broader regulatory action and environmental cleanup efforts, Li added.
The researchers noted that midlife could be a particularly sensitive stage, when the body is more susceptible to stressors associated with aging. (iStock)
Study limitations
The researchers outlined several important limitations of the research, including that the findings show an association, but do not prove that PFAS directly causes accelerated aging.
“The study is cross-sectional, meaning exposure and aging markers were measured at the same time, so we cannot determine causality,” Li told Fox News Digital.
The study was also relatively small, limited to 326 adults age 50 or older, which means the findings may not apply to younger people or broader populations.
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Researchers measured PFAS levels using data collected between 1999 and 2000, and today’s exposure patterns may differ.
Li added that while PFAS is known to persist in the environment and the body, these results should be validated through larger, more recent studies that follow participants over time.
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