Health
Pfizer’s COVID-19 drug Paxlovid in short supply in China
When Li’s 83-year-old father with diabetes began coughing and complaining of physique aches final month, the Beijing resident grew to become anxious about discovering a therapy for COVID-19 in case his mum or dad had caught the virus sweeping town.
He heard at the moment that Pfizer’s anti-viral drug Paxlovid was an efficient therapy, however sufferers may solely get it prescribed in the event that they have been admitted to hospital, and provided that the drug was in inventory.
The primary hospital they visited carried out a CT scan that confirmed his lungs have been contaminated, however turned them away, saying no beds have been accessible, stated Li, who solely gave his surname as a result of sensitivity over how authorities would possibly view his account.
After two extra days of frantic calls to households and associates, a contact lastly discovered them an area at one other hospital, nevertheless it took an extra antigen check and second CT scan earlier than it agreed to prescribe the drug.
Together with his father admitted to an intensive care unit, Li was apprehensive that it had taken too lengthy to get efficient therapy.
“I’m unsure if Paxlovid might help him. I feel it is as a result of when he bought the medication he already had the virus for every week,” Li informed Reuters on Jan.12.
“Now we are able to do little however pray.”
His father died the identical day.
Li’s expertise, native media reviews and on-line posts bear testimony to the difficulties confronted acquiring Paxlovid in China by official channels.
Paxlovid – a mixture of two anti viral medicine – is likely one of the few international oral remedies accepted by Beijing and a scientific trial has discovered it to have decreased hospitalisations in high-risk sufferers by round 90%.
Having been accepted in February final 12 months, Paxlovid was scarcely utilized in China till December when the federal government began lifting its strict containment coverage, and wave of COVID infections started to construct.
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Ramping Up Provides
Chinese language authorities have acknowledged that provides of Paxlovid are nonetheless inadequate to fulfill demand, whilst Pfizer CEO Albert Bourla stated final week that hundreds of programs of the therapy have been shipped to the nation final 12 months and prior to now couple of weeks tens of millions extra have been shipped.
“Pfizer is actively collaborating with Chinese language authorities and all stakeholders to safe an enough provide of Paxlovid in China. We stay dedicated to fulfilling the COVID-19 therapy wants of Chinese language sufferers and partnering with the Chinese language authorities,” the corporate stated in a press release.
Racing to defend in opposition to a rising demise toll, China has additionally accepted Merck & Co’s COVID antiviral drug and is reviewing a therapy developed by Japan’s Shionogi.
Paxlovid is roofed by state insurance coverage — albeit briefly till the tip of March — that means sufferers in idea would solely have to pay $29, a tenth of its regular worth.
However China does not present information on what number of therapy programs are equipped and the place it may be bought, forcing most sufferers to depend on media reviews, word-of-mouth and even importing by unauthorised channels within the gray market.
Those that do handle to discover a provider usually find yourself paying exorbitant costs, as demand has shot up amid an enormous wave of COVID-19 infections.
The official Guangzhou Day by day reported that sufferers on the United Household Healthcare hospital in Guangdong have been paying $891 for well being checks earlier than being allowed to get Paxlovid priced at 2,300 yuan on the hospital.
The hospital didn’t instantly reply to a Reuters’ request for remark.
Well being information agency Airfinity estimated in December that China would wish 49 million programs of the COVID therapy over the subsequent 5 months, with over 22 million wanted in January alone.
The Pfizer drug might be additionally bought for two,170 yuan with prescription through on-line platforms, nevertheless it sometimes sells out inside seconds.
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Paxlovid Present
A number of different folks described to Reuters how they turned to the gray market to buy Paxlovid. Some have been seeking to deal with sick kinfolk, whereas others needed it simply in case.
Chen Jun, a resident of China’s southern Hainan Province, stated he purchased Paxlovid from a provider launched by a enterprise associate, who stated the medication was coming from Hong Kong.
Chen paid $2,972 on Jan. 2 for 2 packing containers for his aged mother and father, who are suffering from most cancers, and he stated that some folks had paid double that worth.
“You will assume it low cost as soon as your loved ones members are in want, as a result of something is healthier than going to a hospital now,” he stated. “I do know individuals who paid 20,000 yuan for one field of the medication.”
One other purchaser who gave his identify as Ray stated he managed to get two packing containers from the US, the place provides are nonetheless ample and a physician’s prescription might be obtained after a web based session.
“It’s totally easy, they do not ask questions,” he stated. Having made the web buy, he then requested a good friend there to assist courier it to China.
An analyst at a Chinese language securities home, who requested anonymity due to sensitivities over the topic, stated his boss went to Hong Kong to refill on Paxlovid to reward purchasers because it was extra valued than a well-liked, costly liquor.
“It’s a higher reward than Moutai.”
Health
Hunters suffer fatal heart attacks while dragging heavy deer, state department reports
At least three deer hunters in Michigan have died from heart attacks this hunting season, according to local reports.
The three men, who were located in Arenac and Tuscola counties, were ages 57, 65 and 83, the report stated.
Two of the men were said to be hauling away heavy deer when they experienced cardiac arrest.
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Michigan’s firearm deer hunting season began on Nov. 15 and runs through Nov. 30, according to the state’s Department of Natural Resources (DNR).
Deer hunting is known to be a potentially dangerous activity for people with heart conditions, according to Dr. Bradley Serwer, a cardiologist and chief medical officer at VitalSolution, a Cincinnati-based company that offers cardiovascular and anesthesiology services to hospitals nationwide.
“The act of deer hunting typically involves hiking to a tree stand or blind, waiting in the cold for hours and then dealing with a sudden surge of adrenaline when a deer is spotted,” he told Fox News Digital.
“Once a hunter hits the deer, they have to track the deer, often for a long distance over rugged terrain,” he continued.
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“When the deer is found, it must be transported back to a vehicle. This typically involves dragging a 100- to 200-pound animal over varied terrain.”
Specific risks for hunters
Prolonged exposure to the cold is a primary risk, Serwer warned, as it can raise blood pressure and cause constriction of the blood vessels in the arms and legs.
“Cold exposure increases the risk of abnormal heart rhythms, particularly ventricular arrhythmias that can cause sudden cardiac arrest,” he said.
“The cold exposure also increases the risk of developing deep vein thrombosis, which can then cause pulmonary embolisms.”
The “sudden surge of adrenaline” when the deer is sighted and shot can also increase the risk of ventricular arrhythmias and sudden cardiac death, the doctor added.
Risks when hunting include cold exposure, adrenaline surges and physical exertion, a cardiologist said.
“Strenuous hiking also places a strain on the cardiovascular system,” Serwer said. “If the hunter is not in good shape, this strain may be too much to bear.”
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Dragging the deer to the vehicle is also a “very strenuous amount of work,” he cautioned, which can lead to overheating and strain.
5 safety tips for deer hunters
Serwer offers the following health tips to reduce cardiac risk when hunting.
1. Maintain good fitness levels
“Stay in shape at baseline so that your body is better equipped to deal with the workload required to track and drag the deer,” he advised.
2. Be prepared for weather conditions
“Stay hydrated, avoid alcohol and tobacco, and dress appropriately,” Serwer recommended. It’s also best to dress in layers to better handle changing temperatures and activity levels.
3. Stay connected and share your location
Carry a phone to ask for help if needed, and ensure that someone knows where you are and when they should expect you back, the doctor suggested.
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4. Keep up with medications
“Don’t forget to take your medications prior to hunting, especially aspirin if it is prescribed,” Serwer said.
5. Buddy up
If possible, experts recommend hunting with a partner who can help with transporting the deer.
Fox News Digital reached out to the Michigan DNR for comment.
Health
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Health
'I'm a pharmacist, and I wouldn't take these 3 vitamin supplements'
There is a variety of guidance about which vitamins and supplements people should take for better health — especially on social media.
Amina Khan, a pharmacist in the U.K. and founder of The Pharmacist Beauty, addressed her nearly 300,000 followers on TikTok about the three supplements she’d never take.
“I think you’re going to be surprised at most of these,” she said in the video, which has nearly one million views.
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Read on to find out the three she pinpointed.
1. Gummy vitamins
While gummy vitamins can taste delicious, Khan considers them “basically just a sugar pill,” she said.
“You might as well go have a sweet,” she said. “They are packed with sugar and filler ingredients, and I know so many of you [are] bingeing these.”
Khan warned that gummy supplements can be “very easily over-consumed” and can lead to mineral toxicity.
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“Some of these gummies don’t even have enough nutrients in them to have an effect on you,” she added.
2. General multivitamins
A multivitamin is often recommended by general practitioners as a good way to get the daily recommended dose of essential nutrients.
But since multivitamins have a “bit of everything” in them, Khan noted that some of the doses of each vitamin are “so low they hardly have an effect on you.”
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Khan added that people most likely don’t need all the vitamins contained in a multivitamin.
3. Vitamins for hair, skin and nails
These types of vitamins have grown in popularity to aid with hair and nail growth, as well as clear skin.
Grouping all three into one pill is “not solution-focused,” according to Khan.
“The most important vitamins in these are often too low to even have an effect on you,” she noted.
Anyone who has questions about taking a vitamin or supplement should consult with a doctor for individualized recommendations.
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