Health
People with brain aneurysms at higher risk of some mental health disorders, study finds
People who have been diagnosed with a brain aneurysm may be more susceptible to certain mental health conditions, according to a study published by the American Heart Association (AHA).
The knowledge of an unruptured aneurysm increased the risk of anxiety, stress, depression, insomnia, bipolar disorder, eating disorders, and alcohol or drug misuse by 10% over a 10-year period, the researchers found.
An unruptured aneurysm occurs when a blood vessel in the brain becomes weak and bulges out — creating the risk of a potentially deadly rupture, per the AHA.
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The effect was most seen in adults under 40 years of age, and the risk was three times greater among those who received an official mental health diagnosis.
The researchers analyzed data for 85,438 adults with untreated aneurysms between 2011 and 2019, comparing them to 331,000 adults without aneurysms.
The data came from the National Health Information Database in South Korea.
The findings were published in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the AHA.
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“As a neurosurgeon who treats cerebral aneurysms, I often see people who do not undergo surgery, yet feel fear and/or anxiety about their condition before each imaging or screening test to monitor their condition,” said study co-author Na-Rae Yang, M.D., PhD, an assistant professor of neurosurgery in the department of neurosurgery at Ewha Womans University College of Medicine in Seoul, South Korea, in a press release.
“Even when it is medically judged and explained that follow-up observation is the best course for their aneurysm rather than surgery, they still worry about the very slim chance of developing a fatal brain bleed.”
The fact that younger adults were more likely to have a “significant psychological burden” could be linked to other life stressors, Yang noted, such as building their career and/or raising a family.
“This elevated rate of mental health conditions suggests that younger people might be particularly vulnerable, highlighting the need for targeted mental health support and interventions for this age group,” she added.
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Dr. Daniel T. Lackland, an American Heart Association EPI and Stroke Council member and professor of epidemiology at the Medical University of South Carolina, was not involved in the study but said he was not surprised by the findings.
“While there is no evidence that aneurysms directly cause anxiety and mental disorders, this study suggests there may be a connection between stress and aneurysms, and that unruptured aneurysms can increase emotional distress,” he told Fox News Digital.
“For example, an enlarging aneurysm may physically affect nearby sympathetic ganglia, which could produce panic or anxiety symptoms.”
Extreme emotional stress could also increase the risk of an enlarged aneurysm rupturing, which could increase anxiety, Lackland added.
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Based on the findings, Lackland recommends maintaining active and regular communication with health providers, particularly for individuals with a family history of brain aneurysms.
“If diagnosed with a brain aneurysm, [the patient should] follow through with the appropriate and proper treatment,” he advised.
“Brain aneurysms, like aortic aneurysms, are life-threatening if they rupture, but can be treated with appropriate therapy and/or procedures.”
Dr. Bradley Serwer, a cardiologist and chief medical officer at VitalSolution, a Cincinnati-based company that offers cardiovascular and anesthesiology services to hospitals nationwide, has also noticed this phenomenon in his own practice.
“Whether the patient is told they have a brain aneurysm or they have an abnormal heart valve, irregular heart rhythm or aortic aneurysm, the psychological ramifications are significant,” Serwer, who was not involved in the research, told Fox News Digital.
Younger patients may have fewer coping mechanisms, he noted.
“They tend to perseverate more on the medical conditions, and this can lead to anxiety.”
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This study highlights the importance of taking a multidisciplinary approach to patient care, Serwer said, as well as the “dramatic need” for more behavioral and mental health services to support these individuals.
Potential limitations
The study did have some limitations, the researchers acknowledged.
The analysis relied on a national database of medical codes rather than input from individual patients.
“Brain aneurysms, like aortic aneurysms, are life-threatening if they rupture, but can be treated with appropriate therapy and/or procedures.”
Additionally, the research did not take into account the size or location of the aneurysms.
Although the findings suggest an association between aneurysms and mental health conditions, they can’t prove cause and effect, the researchers noted.
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“As the authors indicate, there is inadequate evidence to indicate that brain aneurysms cause increased mental health risks,” said Lackland.
“Also, the study was done in Korea — and it is unclear if the results can be generalized to other populations.”
Health
Words and game of Scrabble keep married couple in wedded bliss for decades
A married couple who have long enjoyed the game of Scrabble both together and separately before they even met are never at a loss for words — and attribute their wedded bliss in part to their love of the nostalgic game.
They’re still playing in tournaments built around the game decades after they began doing so.
Graham Harding and his wife Helen Harding, both in their 60s, have been married for over 20 years.
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They met in the 1990s at Scrabble tournaments, as news agency SWNS reported.
But it was a “special match” in 2000 that brought the couple together — and has kept them together now.
Graham Harding is from the East Berkshire Scrabble Club, while his wife Helen is from the Leicester Scrabble Club in the U.K.
They have been taking part in the UK Open Scrabble Championship in Reading this week.
“The more words you know, the more ammunition you’ve got.”
“Scrabble is all about having a good vocabulary,” said Graham Harding, SWNS noted.
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“But it is a Scrabble vocabulary — not necessarily everyday English.”
Added Helen Harding, “The more words you know, the more ammunition you’ve got.”
The couple said they were “vague acquaintances” for about five years after they first met.
Then they got together after a special match in Swindon.
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They maintained a long-distance relationship before they got married in 2004.
The couple even brought their Scrabble board to their wedding.
It featured a message with Scrabble pieces that said, “Congratulations on your wedding day” — while their wedding cake said, in Scrabble letters, “Helen and Graham.”
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They each took up the hobby early in life well before they met each other.
The tournament that’s been taking place this week is the first since the COVID pandemic after a five-year break — and the couple has played some two dozen games in it as of Friday, SWNS reported.
Health
Deep sleep can keep two big health problems at bay, new studies suggest
It might be worth working a little bit harder to get that much-desired, but often elusive, good night’s sleep.
Deep sleep clears the mind of waste just as a “dishwasher” cleans dirty plates and glasses, just-published research suggests — and there’s more.
The findings also offer insights into how sleeping pills may disrupt the “brainwashing” system — potentially affecting cognitive function for people over the long run.
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Study senior author professor Maiken Nedergaard of the University of Rochester and the University of Copenhagen said norepinephrine (a neurotransmitter and hormone) triggers blood vessels to contract — generating slow pulsations that create a rhythmic flow in the surrounding fluid to carry away waste, news agency SWNS noted.
Said Nedergaard, “It’s like turning on the dishwasher before you go to bed and waking up with a clean brain. . . . We’re essentially asking what drives this process and trying to define restorative sleep based on” this “glymphatic clearance.”
The brain has a built-in waste removal process – the glymphatic system – that circulates fluid in the brain and spinal cord to clear out waste, according to the scientists.
The process helps remove toxic proteins that form sticky plaques linked to neurological disorders, such as Alzheimer’s disease.
But the scientists indicated that what drives the system was unclear until now, according to the study.
Is all sleep created equal? The researchers wanted to find out.
To find clues, Nedergaard and her team looked into what happens in mice when their brains sleep, as SWNS reported of the study. The team focused on the relationship between norepinephrine and blood flow during deep sleep.
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They found that norepinephrine waves correlate to variations in brain blood volume — suggesting that norepinephrine triggers a rhythmic pulsation in the blood vessels. The researchers then compared the changes in blood volume to brain fluid flow.
The brain fluid flow fluctuates in correspondence to blood volume changes, suggesting the vessels act as pumps to propel the surrounding brain fluid to flush out waste.
Natalie Hauglund of the University of Copenhagen and the University of Oxford, the study’s lead author, said, “You can view norepinephrine as [the] conductor of an orchestra.”
She added, “There’s a harmony in the constriction and dilation of the arteries, which then drives the cerebrospinal fluid through the brain to remove the waste products.”
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Hauglund said she wanted to understand whether all sleep is created equal.
To find out, the research team administered zolpidem, a common drug to aid sleep, to mice.
“If people aren’t getting the full benefits of sleep, they should be aware of that, so they can make informed decisions.”
They found that the norepinephrine waves during deep sleep were 50% lower in zolpidem-treated mice than in naturally sleeping mice.
Although the zolpidem-treated mice fell asleep more quickly — fluid transport into the brain dropped more than 30%, as SWNS reported.
The researchers say their findings, published in the journal Cell, suggest that the sleeping aid may disrupt the norepinephrine-driven waste clearance during sleep.
Hauglund said, “More and more people are using sleep medication, and it’s really important to know if that’s healthy sleep. If people aren’t getting the full benefits of sleep, they should be aware of that, so they can make informed decisions.”
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The research team said the findings likely apply to humans, who also have a glymphatic system, although it requires further testing.
Nedergaard added, “Now we know norepinephrine is driving the cleaning of the brain, we may figure out how to get people a long and restorative sleep.”
For more Health articles, visit www.foxnews.com/health
Meanwhile, a lack of sleep may be doing more damage than just making people groggy.
It could be sabotaging the brain’s ability to keep intrusive thoughts at bay.
Another new study, this one published in the Proceedings of the National Academy of Sciences, found that sleep deprivation weakens the brain’s defense against unwanted memories, allowing them to flood the mind, according to the New York Post.
“We show that sleep deprivation disrupts prefrontal inhibition of memory retrieval, and that the overnight restoration of this inhibitory mechanism is associated with time spent in rapid eye movement (REM) sleep,” the scientists said.
Health
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