Health
Ozempic’s health benefits keep growing, but are the risks worth it?
One in eight adults in the U.S. has taken Ozempic or another type of GLP-1 drug, surveys show — and now a major new study has revealed a long list of benefits and some little-known risks.
Glucagon-like peptide-1 receptor (GLP-1) agonists — which contain either semaglutide or liraglutide — are prescribed to treat type 2 diabetes and obesity, but previous studies have linked the drugs to other, unexpected benefits.
Researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs (VA) St. Louis Health Care System studied the health outcomes of more than two million veterans with diabetes who took Ozempic or another type of GLP-1 drug between Oct. 1, 2017 and Dec. 31, 2023, according to a university press release.
OZEMPIC ‘MICRODOSING’ IS THE NEW WEIGHT-LOSS TREND
They then compared those outcomes to veterans who took non-GLP-1 diabetes medications.
One in eight adults in the U.S. has taken Ozempic or another type of GLP-1 drug, surveys show. (iStock)
The study, published in the journal Nature on Jan. 20, identified “widespread associations” between Ozempic and some significant health benefits.
Those benefits included reduced risks of neurocognitive disorders like Alzheimer’s and dementia, seizures, and addiction to harmful substances such as alcohol, cannabis, stimulants and opioids.
Other positive health effects included lower risks of suicidal ideation, self-harm, bulimia and psychotic disorders such as schizophrenia.
OZEMPIC COULD HELP REDUCE ALZHEIMER’S RISK FOR SOME, STUDY SUGGESTS: ‘SHIFTING THE PARADIGM’
“GLP-1s have many benefits for at least 42 conditions beyond weight loss – from addiction disorders to memory/cognition problems, blood clots, and infections,” lead study author Ziyad Al-Aly, clinical epidemiologist at Washington University in St. Louis, told Fox News Digital.
Ozempic and other GLP-1 drugs act on receptors in the brain that are involved in impulse control, reward and addiction, Al-Aly noted, which could explain why they are effective in reducing cravings for food and addictive substances.
“GLP-1s have many benefits for at least 42 conditions beyond weight loss.”
“These drugs also reduce inflammation in the brain and result in weight loss; both of these factors may improve brain health and explain the reduced risk of conditions like Alzheimer’s disease and dementia,” he added.
They also found, however, that GLP-1 drugs were linked to several adverse side effects.
Novo Nordisk is the maker of Ozempic, which is approved for type 2 diabetes treatment and reduced risk of cardiovascular events. (Getty Images)
The risk of gastrointestinal problems — including nausea, vomiting, diarrhea and a rarer paralysis of the stomach — were widely known before this new study, the researcher noted.
The new finding, however, was that these drugs can negatively affect the pancreas and kidneys. They were also linked to a higher chance of developing arthritis.
DIABETES AND WEIGHT LOSS DRUGS SHOWN TO REDUCE ALCOHOL-RELATED HOSPITALIZATIONS, STUDY FINDS
“While these adverse effects are uncommon, they can be very serious; physicians must be vigilant for signs of pancreatitis (inflammation of the pancreas) and monitor kidney function among people taking GLP-1RA medications,” Al-Aly stated in the press release.
“Kidney problems can occur without symptoms until the condition is at an advanced stage with limited treatment options.”
Decreased obesity has long been linked with less inflammation in every body system, an expert pointed out. (iStock)
The study, which was funded by the U.S. Department of Veterans Affairs, did have some limitations, the researchers acknowledged.
“This is a discovery approach involving more than two million people and is not a randomized trial,” Al-Aly told Fox News Digital.
“People with real weight loss are happier overall — they feel empowered.”
Seth Kipnis, MD, medical director of bariatric and robotic surgery at Hackensack Meridian Jersey Shore University Medical Center, was not involved in the study but said it confirms what he has seen in his own clinical practice.
“People with real weight loss are happier overall — they feel empowered that they can finally control their weight,” he said in a statement sent to Fox News Digital.
The risk of gastrointestinal problems — including nausea, vomiting, diarrhea and a rarer paralysis of the stomach — were widely known before this new study. (iStock)
Decreased obesity has long been linked with less inflammation in every body system, Kipnis pointed out.
“GI problems and renal problems will always be seen if people are not eating correctly and maintaining hydration,” he said. “If you take these medications without nutritional education, they can be harmful.”
Recommendations and predictions
Based on the findings, the researchers noted, people should be aware that these drugs have not only a “broad beneficial profile,” but also important risks.
“People should use the information to discuss with their provider whether GLP-1 is the right medication for them,” Al-Aly recommended.
“A person with a lot of GI issues may find these meds intolerable.”
“A person who is trying to lose weight and quit smoking or drinking may find GLP-1s especially useful – helping hit two birds with one stone — but a person with a lot of GI (gastrointestinal) issues may find these meds intolerable,” he went on.
“Each person’s health profile is different. Pros and cons should be discussed with the provider.”
CHEAP OZEMPIC KNOCK-OFFS HAVE RISEN IN POPULARITY
Given their effectiveness at causing weight loss and improving health, GLP-1 drugs will likely become more common and increase in use, Hackensack’s Kipnis predicted.
“We have been prescribing many long-term drugs for hypertension, heart disease, high cholesterol, diabetes, arthritis, reflux and many other diseases without hesitation,” he said.
The new study revealed that GLP-1 drugs could negatively affect the pancreas and kidneys. (iStock)
“This new class of drug, as it lowers obesity, has the potential to lower the use of every other drug that is used to treat obesity-related conditions.”
Not every doctor should prescribe these medications, however, according to Kipnis.
“Doctors with weight management programs and nutrition education programs would likely have better outcomes and fewer side effects,” the doctor said.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Novo Nordisk, the maker of Ozempic (approved for type 2 diabetes treatment and reduced risk of cardiovascular events) and Wegovy (approved for weight management and reduced risk of cardiovascular events), provided the following statement to Fox News Digital.
“Semaglutide has helped millions of people fight chronic diseases such as type 2 diabetes, cardiovascular disease and obesity. As we look to help even more people with chronic diseases, we are exploring the potential of semaglutide in several other disease states.”
Wegovy, also made by Novo Nordisk, is FDA-approved for weight management and reduced risk of cardiovascular events. (Steve Christo – Corbis/Corbis via Getty Images)
“Patient safety is of utmost importance to Novo Nordisk. The known risks and benefits of semaglutide medicines are described in their FDA-approved product labeling and we work closely with authorities and regulatory bodies worldwide to continuously monitor the safety profile of our products.”
For more Health articles, visit www.foxnews.com/health
The company added that the “totality of data” from previous studies “provides reassurance of the safety profile of semaglutide.”
Health
Dr Oz links obesity to chronic disease surge, says GLP-1s can ‘jumpstart’ better health
NEWYou can now listen to Fox News articles!
Washington, DC – GLP-1 weight-loss drugs have become a prevalent part of American healthcare, and the current administration is getting behind the movement.
In an exclusive interview with Fox News Digital at the Great American State Fair in the nation’s capital on July 6, CMS Administrator Dr. Mehmet Oz voiced his support for the use of GLP-1 (glucagon-like peptide-1) medications, such as Ozempic, for appropriate uses.
“I’m a fan of GLP-1 drugs when used correctly,” he said. “They do help people who are overweight lose weight quite effectively. They’re not a replacement for diet and exercise, but they might jumpstart the system so it’s easier for you to use healthier tactics.”
DR OZ WARNS MEDICARE SCAMMERS ARE STEALING BILLIONS — AND YOUR PERSONAL INFORMATION COULD BE NEXT
This is especially helpful for those who may have trouble moving due to joint pain or are experiencing internal dysfunction, Oz said.
Certain GLP-1 drugs are covered by Medicare for overweight candidates with certain conditions, such as high blood pressure and diabetes, and Oz projected the benefits will continue to benefit taxpayers.
Dr. Mehmet Oz is pictured in Washington, D.C., at the Great American State Fair, where he spoke about federal health policy. (Angelica Stabile/Fox News Digital)
“We believe these are so effective in reducing conditions like high blood pressure and diabetes that they’ll actually save money for the federal taxpayer, because [they’re] going to make you healthy enough that you don’t have to consume health services,” Oz said.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
“We think about 70% of all the money we spend on healthcare is caused by chronic conditions, and obesity is the No. 1 driver of all that, so it’s a smart decision.”
Oz recently announced the launch of the Medicare GLP-1 Bridge program, which will allow more seniors to access GLP-1 drugs for only $50 a month if they meet qualifying health criteria and receive prior authorization from a doctor.
The doctor expressed support for broadening affordable access to GLP-1 medications for Americans. (iStock)
“There are a lot of overweight people who don’t have high blood pressure, diabetes or other conditions, so they don’t get access to the drug normally,” he said. “We want them to have the ability to use it as well.”
Although these access shifts could boost Americans’ overall health — and in some cases could be lifesaving — Oz noted that there is “no silver bullet” when it comes to these medications.
CLICK HERE FOR MORE HEALTH STORIES
“I love the fact that the innovation that’s coming out of pharmaceutical companies is allowing us to save lives and make lives better,” he said. “But the real secret to longevity is eating right, exercising, sleeping, dealing with the stress of your life, finding some purpose in your existence [and] realizing you have agency over the future.”
“These are things that your mom would have told you [and that] you don’t need a doctor to be emphasizing.”
Medicating appropriately, combined with eating right, exercising and staying connected with others, can help make health goals attainable, the doctor said. (iStock)
While GLP-1s may not be a fix-all, combining these medications with foundational health practices “makes a lot of sense,” Oz said.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
“I don’t want people being fat-shamed … I don’t want you feeling guilty that you’re gaining weight even though everyone else around you seems to have figured it out,” he said. “It’s not that simple — our set points for hunger are different. We have different things going on in our lives.”
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
“But if you realize how precious you are — the temple of the soul is so valuable. It’s the greatest gift your parents ever gave you, and you take advantage of every tool out there to make it work … which includes using medications when appropriate. That, to me, is MAHA.”
Health
Deadly Legionnaires’ disease outbreak sparks concern in major US city: Know the symptoms
NEWYou can now listen to Fox News articles!
Amid warnings of a Legionnaires’ disease outbreak on Manhattan’s Upper East Side, health experts say that early recognition of symptoms can mean the difference between a quick recovery and life-threatening complications, especially for high-risk groups.
New York City health officials are urging anyone who has visited the east side of Central Park or Manhattan’s Upper East Side since late June to watch for symptoms.
As of July 6, the New York City Health Department had confirmed 23 cases and 17 hospitalizations associated with the respiratory infection. No deaths have been reported.
NYC HEALTH OFFICIALS WARN OF LEGIONNAIRES’ DISEASE OUTBREAK IN CENTRAL PARK AREA
Officials are investigating contaminated cooling towers as the likely source. They have emphasized that the illness is not spread person-to-person and is not linked to the city’s drinking water.
Health experts say that early recognition of symptoms can mean the difference between a quick recovery and life-threatening complications, especially for high-risk groups. (iStock)
“Legionnaires’ disease is deadly but can be effectively treated if diagnosed early,” said NYC Health Commissioner Dr. Alister Martin in a press release. “New Yorkers at higher risk, including anyone who is 50 and older, those who smoke or people with chronic lung conditions should be especially mindful of their symptoms and seek care as soon as symptoms begin.”
What is Legionnaires’?
Legionnaires’ disease is a type of pneumonia caused by Legionella bacteria.
The bacteria is usually found in lakes, streams and other freshwater environments, but can grow in any area where water sits for a long time, according to the CDC.
RARE TICK-BORNE VIRUS TURNS DEADLY FAST AS US CASES REACH RECORD HIGH, EXPERTS WARN
That can include shower heads, sink faucets, hot tubs, water features/fountains, plumbing systems and other water systems.
When people swallow or breathe in droplets of water that contain Legionella, they can potentially become ill.
Although human transmission is possible in rare cases, the disease is not typically transmitted among people, per the Centers for Disease Control and Prevention.
Symptoms of infection
Infections can lead to severe pneumonia in older people and those with compromised immune systems, according to Dr. Andrew Handel, a pediatric infectious diseases expert at Stony Brook Children’s Hospital on Long Island, New York.
Symptoms of Legionnaires’ disease usually show up between two and 14 days after exposure.
New York City health officials are urging anyone who has visited the east side of Central Park or Manhattan’s Upper East Side since late June to watch for symptoms. (iStock)
“Legionella infections cause symptoms that are similar to other forms of pneumonia — fever, coughing, difficulty breathing, shortness of breath and chest pain,” Handel previously told Fox News Digital.
“Legionnaires’ disease is deadly but can be effectively treated if diagnosed early.”
The signs are similar to other types of pneumonia, and include the following:
- Cough
- Fever
- Shortness of breath
- Muscle aches and headaches
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
Some patients may also experience nausea, diarrhea and confusion, the CDC noted.
Diagnosis, treatment and prevention
A medical professional can diagnose the infection with laboratory tests and chest X-rays.
The condition is typically treated with antibiotics. In cases of severe infection, hospitalization may be required for breathing support and IV hydration.
Around 10% of people who contract Legionnaires’ disease will die from those complications — and the mortality risk rises to 25% for those who get Legionnaires’ while staying in a healthcare facility, according to the CDC.
The bacteria is usually found in lakes, streams and other freshwater environments, but can grow in any area where water sits for a long time, according to the CDC. (iStock)
“Treatment needs to be early and aggressive,” Dr. Nathan Goodyear, an Arizona-based integrative medicine expert, previously told Fox News Digital. “Legionella infection is an intracellular infection that requires antibiotic treatment.”
Antibiotics that are appropriate for Legionella infection include Levofloxacin and Azithromycin.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
“Therapy can be prescribed orally in healthy individuals… but intravenous antibiotics often prove to be the initial option for treatment secondary to the pathogenicity of the disease,” Goodyear said.
Currently, there are no vaccines for Legionnaires’ disease.
CLICK HERE FOR MORE HEALTH STORIES
The best strategy to prevent infection is to reduce the growth and spread of the Legionella bacteria. The CDC recommends that building owners and managers use a water management program to reduce the risk.
“New Yorkers at higher risk, including anyone who is 50 and older, those who smoke or people with chronic lung conditions should be especially mindful of their symptoms and seek care as soon as symptoms begin,” city officials stated. (iStock)
To prevent serious illness from Legionnaires’, Goodyear recommends that all smokers kick the habit, and also emphasizes the need to “aggressively support” chronic pulmonary disease.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
“Increasing immune support (vitamin D3, vitamin C, Zinc) is required to counter the immune dysfunction associated with advancing age.”
Obesity is another foundational risk factor for all chronic inflammatory diseases, the doctor added.
Health
Katie Couric couldn’t remember the year or the president during frightening brain episode
NEWYou can now listen to Fox News articles!
Journalist Katie Couric is sharing a scary medical episode that she experienced on June 27.
In a post on Substack titled “The Day I’ll Never Remember,” she detailed a sudden episode that left her unable to recall the current month, year and president.
“I thought it was 2024. And I believed Joe Biden was president,” she wrote.
ONE WALKING HABIT COULD SIGNAL A HEALTHIER BRAIN AFTER 80, SCIENTISTS SAY
The event occurred while Couric was attending the Aspen Ideas Festival in Colorado, during which she participated in two public panels — one on AI and one on journalism — both of which she cannot remember at all.
“I have no idea what we talked about, or of what occurred when the panels ended,” she said.
Journalist Katie Couric is sharing a scary medical episode that she experienced on June 27. (Getty Images)
John Molner — Couric’s husband, who was in attendance at the festival and the two panels — also shared his account.
After the event, someone told Molner that Katie wasn’t feeling well. When he reached her, an EMT and a doctor were tending to her. “I could tell something was off,” he wrote. “It could have been altitude sickness, but Katie was definitely not all there.”
WOMAN WITH ADVANCED ALZHEIMER’S REGAINED SPEECH AND MEMORIES AFTER TAKING MAGIC MUSHROOMS
At the hospital, when Couric struggled to recall the year, the president and her grandchildren’s names, doctors began checking for a stroke.
An MRI revealed no signs of stroke, which was a relief, but “Katie’s ‘fog’ became a lot more apparent,” Molner wrote.
John Molner, Couric’s husband, who was in attendance at the festival and the two panels, also shared his account. (Getty Images)
“She repeatedly asked me the same questions: ‘What was I doing before we got to the hospital?’ ‘Why am I at the hospital?’”
Couric was ultimately diagnosed with transient global amnesia, a sudden, temporary episode of memory loss that prevents a person from forming new memories and may also erase some recent memories, according to Mayo Clinic.
“The cause seems to be as mysterious as the brain itself.”
It is not caused by a stroke, seizure or head injury, and it usually resolves completely within 24 hours.
“[It’s] just a very weird neural episode that’s pretty uncommon and, at least in most cases, is a ‘one and done’ experience,” Molner said.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
Couric said she finally began feeling “like herself” again around 9 p.m. and went to sleep at 2 a.m.
As TGA leaves a “permanent gap in memory” for the duration of the episode and for hours beforehand, Couric said that from around noon on that day until at least 7 p.m. will remain a “big, black hole.”
As TGA leaves a “permanent gap in memory” for the duration of the episode and for hours beforehand, Couric said that from around noon on that day until at least 7 p.m. will remain a “big, black hole.” (Getty Images)
Data shows that approximately three to eight people per 100,000 will have an episode of transient global amnesia, with people 50 years of age and older at higher risk.
The specific cause of TGA is not known, but some experts believe it stems from a “temporary dysfunction in the brain’s hippocampus — the area responsible for creating new memories,” Couric shared.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
“Doctors believe this is driven by brief interruptions in blood or oxygen flow, or microscopic spasm in the blood vessels.”
Episodes could potentially be triggered by intense physical exertion, emotional distress, extreme temperature changes or migraines, experts say.
CLICK HERE FOR MORE HEALTH STORIES
Approximately 15% of patients will have a recurrence 10 years later.
“Why did this happen to me? Was the altitude an issue? Was I dehydrated? Tired? Stressed? The literature doesn’t seem to indicate that these are contributing factors, but the cause seems to be as mysterious as the brain itself,” Couric wrote.
Anyone who experiences sudden memory loss, confusion, difficulty speaking, weakness, numbness, vision changes, severe headache or other stroke-like symptoms should seek immediate medical attention or call 911, doctors advise. (iStock)
“All I know is that those hours will be forever lost. Someone described it as my brain failing to hit the ‘record button.’”
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
“While this was a freaky occurrence, it could have been much more serious. So ultimately, I’m relieved — even though several hours of a Saturday in June will always be missing for me.”
Anyone who experiences sudden memory loss, confusion, difficulty speaking, weakness, numbness, vision changes, severe headache or other stroke-like symptoms should seek immediate medical attention or call 911, doctors advise.
-
Politics5 minutes agoIran ceasefire is ‘over,’ Trump says, and orders additional strikes
-
Science8 minutes agoDiarrhea-causing cyclosporiasis exceeds 1,000 cases in U.S. What Californians should know
-
Sports13 minutes agoArthur Fery’s fairy-tale Wimbledon run puts British wild card on brink of history
-
World23 minutes agoBurnham on course to become next UK PM with backing of 322 Labour MPs
-
News50 minutes agoTrump fires last members of election commission, inciting fears of midterm ‘chaos’
-
Los Angeles, Ca2 hours agoCalifornia teen e-biker baiting police to chase tracked by drone, arrested
-
Detroit, MI2 hours agoOur picks for state\nSenate from Wayne Co. | Endorsements
-
San Francisco, CA3 hours agoMan reported missing in San Francisco