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Ozempic patients may face dangerous risks during surgery, doctors warn

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Ozempic patients may face dangerous risks during surgery, doctors warn

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Patients who are taking GLP-1 medications such as Ozempic, Wegovy, Mounjaro and others could face complications during surgery, recent research has shown.

In one study led by UTHealth Houston, more than half of patients taking GLP-1s had “significant gastric contents” before going into surgery, even if they had followed pre-op fasting protocols, according to a press release on the university’s website.

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This could lead to a potentially life-threatening condition called pulmonary aspiration, when food or liquid is inhaled into the lungs.

OZEMPIC AND WEGOVY COULD DOUBLE AS KIDNEY DISEASE TREATMENT, STUDY SUGGESTS

GLP-1 (glucagon-like peptide) receptor agonists are commonly prescribed to patients with type 2 diabetes (to stabilize blood glucose levels) or obesity (to assist with weight loss).

“These medications slow down digestion, which means food stays in the stomach longer,” said Dr. Alfred Bonati, the founder of the Bonati Spine Institute in Florida.

Patients who are taking GLP-1 medications such as Ozempic, Wegovy, Mounjaro and others could face complications during surgery, recent research has shown. (iStock; Getty Images)

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Pulmonary aspiration can cause severe lung damage, infections or even death, Bonati warned.

“General anesthesia can also cause nausea, and the slowed digestion from weight-loss meds can exacerbate this, leading to a higher risk of vomiting during surgery,” he said.

“These medications slow down digestion, which means food stays in the stomach longer.”

Dr. Brett Osborn, a board-certified neurosurgeon and section chief at St. Mary’s Medical Center in Florida, always advises his patients who are taking GLP-1 agonists to stop the medication at least one week before a surgical procedure, he said. 

In addition to aspiration, Osborn warned of the increased risk of postoperative ileus, a dysfunction of the intestines after surgery.

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Close-up of Ozempic pens and person injecting needle in background

GLP-1 (glucagon-like peptide) receptor agonists are commonly prescribed to patients with type 2 diabetes, to stabilize blood glucose levels — or patients with obesity, to assist with weight loss. (iStock)

“This could predispose patients to significant problems, including bowel ischemia (a rare circulatory condition that occurs when blood flow to the intestines is reduced),” he told Fox News Digital.

Healing is a secondary concern among patients taking GLP-1s, according to Osborn. 

OZEMPIC BABIES: WOMEN CLAIM WEIGHT-LOSS DRUGS ARE MAKING THEM MORE FERTILE AND EXPERTS AGREE

“Those following a hypocaloric diet, as is the case with patients on GLP-1 agonists, may potentially inhibit healing and recovery from surgery, which requires a caloric surplus, particularly from protein-laden foods,” he said. 

Proper nutrition is crucial for tissue recovery, Osborn said.

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Proper nutrition is essential to healing after surgery, a doctor said. (iStock)

“By inducing a relative state of malnutrition, these medications can be problematic in perioperative patients.”

Dr. Jean-Carlos Jimenez, medical director at Attune Med Spa in Connecticut, agreed that these medications can lead to complications during surgery.

ASK A DOCTOR: ‘WHAT SHOULD I DO, OR NOT DO, PRIOR TO SURGERY?’

“GLP-1 agonists can cause nausea, vomiting and something known as delayed gastric emptying, or gastroparesis — which means the stomach takes longer than usual to empty its contents into the small intestines,” he told Fox News Digital via email.

“Residual gastric content can increase the risk of pulmonary aspiration during anesthesia and potentially worsen post-operative recovery.”

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Nurse in hospital

Surgery is known to alter blood sugar levels due to stress from the procedure, a doctor noted. (iStock)

Surgery is also known to alter blood sugar levels due to stress from the procedure, Jimenez added.

Due to these risks, doctors agree that patients should review all the medications they’re taking with their surgeon and anesthesiologist. 

     

For surgical procedures that require patients to fast or remain on a clear liquid diet, they may need to do this for a longer period of time, said Jimenez.

“The timing of when to stop will depend on the type of GLP-1 agonists a patient uses, but can range from holding the daily dose on the day of surgery to holding the scheduled weekly dose one week before a planned procedure,” he told Fox News Digital.

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GLP-1s typically can be restarted at the next scheduled dose, but should be carefully monitored by the doctor, he advised.

The timing can depend on the type of surgery and the patient’s overall condition, according to Bonati.

Surgery preparation

Due to the risks, doctors say patients should review all their medications with the surgeon and anesthesiologist.  (iStock)

“It’s crucial to follow the instructions provided by the health care providers, as they will tailor the advice to your individual health needs and the specifics of your surgery,” he added.

In June 2023, the American Society of Anesthesiologists published an announcement warning of the risks and recommending that patients consider pausing their doses in the days or weeks leading up to an elective surgical procedure.

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The American Association of Nurse Anesthesiology has issued a similar recommendation.

Fox News Digital contacted Novo Nordisk, maker of Ozempic and Wegovy, requesting comment.

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These 17 cancer types are more common in Gen X and millennials, as study notes 'alarming trend'

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These 17 cancer types are more common in Gen X and millennials, as study notes 'alarming trend'

Certain types of cancers are more prevalent among Gen X and millennials, according to a new study led by the American Cancer Society (ACS).

The study, published in the journal The Lancet Public Health, analyzed data from over 23 million patients who were diagnosed with 34 different types of cancer over two decades.

The patients ranged in age from 25 to 84, representing multiple generations.

RISKS, SYMPTOMS AND TREATMENTS FOR LUNG CANCER, THE DEADLIEST CANCER IN THE WORLD

Researchers found that the prevalence of small intestine cancer, kidney cancer and pancreatic cancer was two to three times higher in those born in 1990 than those born in 1955 for both males and females, and for liver cancer in females, according to an ACS press release.

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Rates were also higher among younger groups for breast cancer (estrogen-receptor positive), uterine cancer, colorectal cancer, non-cardia gastric cancer, gallbladder cancer, ovarian cancer, testicular cancer, anal cancer in males and Kaposi sarcoma in males, the study found. 

Certain types of cancers are more prevalent among Gen X and millennials, according to a new study led by the American Cancer Society. (iStock)

Other cancers that were more prevalent in younger groups included myeloma, leukemia, cardia gastric cancer, and non-HPV-associated oropharyngeal cancer (in women).

ASPIRIN MAY BE LINKED TO LOWER RISK OF COLORECTAL CANCER, NEW STUDY SUGGESTS

Death rates also rose among younger groups for liver cancer (females), gallbladder cancer, uterine cancer, testicular cancer and colorectal cancer.

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“These findings add to growing evidence of increased cancer risk in post-baby boomer generations, expanding on previous findings of early-onset colorectal cancer and a few obesity-associated cancers to encompass a broader range of cancer types,” said Dr. Hyuna Sung, lead author of the study and a senior principal scientist of surveillance and health equity science at the American Cancer Society, in the ACS release. 

Mammogram results

The incidence of cancer among people under age 50 around the world is projected to increase by 31% by 2030, studies have shown. (iStock)

“Birth cohorts, groups of people classified by their birth year, share unique social, economic, political and climate environments, which affect their exposure to cancer risk factors during their crucial developmental years.”

While researchers have identified some cancer trends associated with certain age groups, they don’t yet have a clear explanation for why these rates are rising, Sung added.

ARTIFICIAL INTELLIGENCE DETECTS CANCER WITH 25% GREATER ACCURACY THAN DOCTORS IN UCLA STUDY

Cancer has historically been associated with aging, yet doctors have seen an “alarming trend” of surging cases among those under 50 years of age, according to Edward S. Kim, M.D., the physician-in-chief of City of Hope Orange County and vice physician-in-chief of City of Hope National Medical Center in California. 

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“It is vital that we identify the reasons behind this trend.”

“This latest trend indicating increases in early onset cancer is a paradigm shift,” Kim, who was not involved in the study, told Fox News Digital via email.

“It is vital that we identify the reasons behind this trend, educate the public, advance prevention and early diagnosis, and develop more effective treatments.”

Man cancer treatment

While researchers have identified some cancer trends associated with certain age groups, they don’t yet have a clear explanation for why these rates are rising, a researcher said. (iStock)

There is “considerable evidence” pointing to environmental causes of early-onset cancers, according to Kim. 

“We cannot deny that an extensive range of environmental factors have rapidly transformed in developed countries since the mid-20th century,” he said. 

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While controlling these factors can be difficult, Kim said, modifications to diet and lifestyle could make a substantial impact — particularly when implemented in youth and early adulthood.

“Caring for our gut’s microbiome — the internal mechanism responsible for absorption of vitamins, regulation of the immune system, and assistance with food digestion – is essential,” he said.

Close up shot of a woman holding a plate of fresh green salad in the beautiful morning light. She's holding a fork and she's about to eat the vegetarian food. Healthy eating and diet concept. Shallow depth of field with focus on the fork.

Embracing a healthier lifestyle has been linked to reduced cancer rates, experts say. (iStock)

To ensure a healthy microbiome, the doctor recommends avoiding ultra-processed foods, exercising to prevent obesity, and avoiding smoking and alcohol consumption.

It is also important for health care providers to make cancer screening options more accessible for younger people, Kim said.

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“All too often, primary care physicians may not recommend early screenings, because cancer has traditionally been associated with older ages and the screening guidelines have focused on age-based strategies,” he said. 

      

“Expanding cancer research efforts focused on younger individuals is another critical area for improvement,” Kim added. 

doctor and patient

“Expanding cancer research efforts focused on younger individuals is another critical area for improvement,” an oncologist said. (iStock)

The ACS also calls for access to “affordable, comprehensive health insurance” for younger generations to increase screening rates.

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The incidence of cancer among people under age 50 around the world is projected to increase by 31% by 2030, studies have shown.

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“There is an epidemic of young people being diagnosed with cancer occurring right in front of us, and unless we implement some urgent interventions, I fear we will continue to observe more young people with cancer over the next decade,” Kim said.

“We cannot wait that long.”

Fox News Digital reached out to the ACS researchers for additional comment.

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AI fast-tracks dementia diagnoses by tapping into ‘hidden information’ in brain waves

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AI fast-tracks dementia diagnoses by tapping into ‘hidden information’ in brain waves

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As dementia becomes more widespread, Mayo Clinic researchers believe that artificial intelligence is the key to enabling earlier and faster diagnoses.

By pairing AI and EEG (electroencephalogram) tests, the team at the Mayo Clinic Neurology AI Program (NAIP) in Rochester, Minnesota, was able to identify specific types of dementia sooner than they would have through human analysis.

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Based on these findings, EEGs could eventually provide a more accessible, less expensive and less invasive way to assess brain health earlier, according to a hospital press release.

WHAT IS ARTIFICIAL INTELLIGENCE?

The research was published last week in the journal Brain Communications.

What is an EEG?

With an EEG, a technician attaches small metal electrodes to the patient’s scalp, which measure electrical activity in the brain.

The test produces a recording of wavy lines that represent the brain’s electrical impulses. 

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An electroencephalogram (EEG) is a test that measures electrical activity in the brain using small, metal discs (electrodes) attached to the scalp. This activity shows up as wavy lines on an EEG recording. (iStock)

It is primarily used to diagnose epilepsy, but can also be used to identify other brain conditions, according to Dr. David Jones, a practicing clinician specializing in behavioral neurology, who directs the artificial intelligence program at Mayo Clinic in Minnesota.

MAYO CLINIC FINDS NEW TYPE OF MEMORY LOSS THAT’S OFTEN MISTAKEN FOR ALZHEIMER’S

The clinic performs thousands of EEGs each year to evaluate patients with neurological problems.

It’s been known for some time that brain wave patterns change in patients with dementia or cognitive problems caused by Alzheimer’s disease or Lewy body disease, Jones said in a phone interview with Fox News Digital.

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“However, it takes a lot of specialized analysis, expertise and manual labor to extract that information, so Alzheimer’s and dementia are not routinely assessed on EEG.”

Tapping into ‘hidden information’

With this study, the researchers set out to find “hidden information” in patients’ brain waves using computer algorithms, without manual labor, Jones said.

The AI tool was built in-house at Mayo Clinic, trained on data from more than 11,000 patients who received EEGs over a decade-long period.

Doctor applying EEG electrodes

EEGs are primarily used to diagnose epilepsy, but they can also be used to identify other brain conditions. (iStock)

In analyzing complex brain waves, the model identified six specific patterns that appeared in patients with Alzheimer’s or Lewy body disease that were not found in those who had no cognitive trouble, according to Jones.

The correlation was confirmed by also looking at other measures, such as cognitive testing, blood biomarkers and brain PET scans.

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ALZHEIMER’S ON MOTHER’S SIDE OF THE FAMILY COULD INCREASE DISEASE RISK, STUDY FINDS

Overall, the AI tool decreased the EEG reading time by 50% and increased the accuracy of those readings “pretty significantly,” Jones said.

“This tells us that there is a lot of unused information in clinically acquired EEGs that we can extract automatically — and now we can begin to build better tools, algorithms and methods,” Jones said.

Rochester, Minnesota, August 2, 2019 - The Mayo Clinic nonprofit Hospital Methodist Campus located in Rochester Minnesota USA

The team at the Mayo Clinic Neurology AI Program (NAIP) in Rochester, Minnesota, was able to identify specific types of dementia sooner than they would have with human analysis. (iStock)

It would be “very difficult” to perform this type of analysis at scale without AI or machine learning technology, according to the neurologist.

‘Significant leap forward’

Harvey Castro, a Dallas-based board-certified emergency medicine physician and national speaker on artificial intelligence in health care, was not involved in the study but referred to Mayo Clinic’s research as “a significant leap forward.”

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“This technology can rapidly and precisely analyze brain wave patterns, identifying early signs of dementia often invisible to the human eye,” he told Fox News Digital.

“There is a lot of unused information in clinically acquired EEGs that we can extract automatically.”

As an ER doctor, Castro said he does not typically use EEGs due to the time required to interpret the results.

“However, AI technology allows for fast processing of large amounts of data, facilitating quicker, more informed decisions about a patient’s cognitive health,” he said. 

“As a result, I can see this becoming a new tool for me to use in the ER.”

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Woman getting an EEG

The end goal is to incorporate brain scans, blood work, cognitive tests and brain waves into “one complete model of brain health,” a researcher said. (iStock)

AI-driven EEG analysis could be a “game-changer” in rural and underserved areas, according to Castro. 

“It provides a cost-effective, non-invasive method to screen for cognitive issues early, where advanced diagnostic tools like MRIs or PET scans are limited.”

Next steps

The ultimate goal is to include this AI-driven EEG analysis into a “multimodal” approach to dementia testing, according to Jones.

“That means being able to model brain scans, blood work, cognitive tests and brain waves into one complete model of brain health,” he told Fox News Digital.

ARTIFICIAL INTELLIGENCE DETECTS CANCER WITH 25% GREATER ACCURACY THAN DOCTORS IN UCLA STUDY

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The next step is to implement the AI tool into routine clinical practice.

“So if you’re coming in and having an EEG for epilepsy or a sleep study, we’ll also simultaneously be able to tell you something about your cognitive health, and whether we see something that means you might need to see a behavioral neurologist,” Jones said.

Man brainwave scanning

There are still several years of research ahead before this technology becomes widely accessible, the researcher noted. (iStock)

In the future, the neurologist envisions EEGs becoming a “highly scalable and portable” technology, where people can even perform cognitive assessments remotely — “in the same way that you measure blood pressure or heart rate in your own home.”

      

There are still several years of research ahead before this technology becomes widely accessible, Jones noted.

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Potential risks and limitations

Despite the benefits of this type of technology, Castro cautioned that there are challenges with integrating AI into clinical practice. 

“While AI can provide valuable insights, the clinician’s expertise and empathy remain irreplaceable.”

“These include the need for substantial training for health care professionals to use these tools effectively and the potential for over-reliance on AI at the expense of clinical judgment,” he told Fox News Digital.

It’s also important to balance the use of AI with a “human touch,” Castro said.

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“While AI can provide valuable insights, the clinician’s expertise and empathy remain irreplaceable in delivering holistic patient care.”

Other considerations include ensuring patient data privacy, obtaining informed consent and working to prevent biases in AI algorithms, the doctor added.

AI dementia model

In analyzing complex brain waves, the model identified six specific patterns that appeared in patients with Alzheimer’s or Lewy body disease that were not found in those who had no cognitive trouble. (iStock)

Jones, the Mayo Clinic neurologist, acknowledged that there are risks in relying too heavily on algorithms, but emphasized that the technology is designed using “real-world data for real-world use.”

“Its value is gauged by whether it’s helping us take care of our patients — that’s our focus.”

For more Health articles, visit www.foxnews/health

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The team is “well aware” of potential problems and takes steps to mitigate them, Jones told Fox News Digital.

“We follow good AI and machine learning practices as part of the ethos of our software design and the values of Mayo Clinic.”

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