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Nutrient deficiency linked to heart disease risk for millions, new study warns

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Nutrient deficiency linked to heart disease risk for millions, new study warns

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More than three-quarters of the global population is falling short on omega-3 intake, a nutrient gap that may increase the risk of heart disease, cognitive decline, inflammation and vision problems.

That’s according to an analysis published in Nutrition Research Reviews, in which researchers from the University of East Anglia, the University of Southampton and Holland & Barrett analyzed omega-3 intake patterns across multiple countries and age groups.

The review found that 76% of people worldwide are not meeting the recommended levels of two omega-3 fats that are essential for heart health: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

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The analysis considered recommendations from global health authorities and assessed how closely populations follow them.

Most adults should aim for at least 250 milligrams of EPA and DHA per day, though actual intake is far lower in many regions, according to the researchers.

A new study found that 76% of people fall short of their recommended omega-3 intake. (iStock)

To explore the health implications of low omega-3 intake, Fox News Digital spoke with Michelle Routhenstein, a New York–based preventive cardiology dietitian at Entirely Nourished.

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Low omega-3 levels can have a noticeable impact on heart health, cognitive function and inflammation throughout the body, the expert confirmed.

Low intake can also increase the risk of heart attacks and sudden cardiac death, she added. It’s also associated with higher triglycerides, irregular heart rhythms and plaque in the arteries.

Most adults should aim for at least 250 milligrams of EPA and DHA per day, researchers say.  (iStock)

Inadequate omega-3 levels have also been linked to changes in brain function, including faster cognitive decline, a higher risk of Alzheimer’s disease and increased rates of depression.

Routhenstein noted that low levels may also worsen inflammation in autoimmune conditions such as psoriasis, and can negatively affect eye health, since omega-3s play a key structural role in the retina.

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To improve omega-3 levels, the expert said it’s important to understand how much is needed and where to get it.

“The richest dietary sources of EPA and DHA are oily fish, such as salmon, mackerel, sardines, herring, trout and anchovies,” Routhenstein told Fox News Digital.

Oily fish, such as salmon, are among the richest natural sources of omega-3s. (iStock)

Many people benefit from eating oily fish more frequently, often three to four times per week, Routhenstein noted. For individuals who do not eat fish regularly, supplements can help raise EPA and DHA to healthier levels.

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For those taking omega-3 supplements, dosing should be based on lab results, medications, omega-3 levels and overall medical history, according to Routhenstein. Moderate, quality-controlled supplements are generally considered safe for most people.

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There is also some evidence supporting prescription-strength omega-3 products.

“High-dose EPA, such as 4 grams per day of icosapent ethyl, has been shown to reduce major cardiovascular events in certain high-risk populations, while similar doses of mixed EPA/DHA have not consistently shown the same benefit,” Routhenstein said.

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Omega-3 dosing should be individualized based on lab data, medication use, current levels and overall medical history. (iStock)

Testing omega-3 levels can also help determine whether intake is adequate. The omega-3 index, a blood test that measures EPA and DHA in red blood cells, is considered one of the most reliable ways to assess status.

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“Levels around 8% are associated with lower cardiovascular risk, while levels below approximately 4% are considered low,” Routhenstein said.

Understanding baseline levels can help guide more personalized decisions about diet and supplementation.

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Those who are unsure about their omega-3 status or whether supplementation is appropriate should speak with a healthcare provider to determine the best approach.

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Tai Chi Walking Boosts Weight Loss After 50—With Less Joint Pain and Stress

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Tai Chi Walking Boosts Weight Loss After 50—With Less Joint Pain and Stress


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Chronic back pain may have met its match with hormone treatment, scientists say

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Chronic back pain may have met its match with hormone treatment, scientists say

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A hormone traditionally used to treat bone loss may hold the key to stopping chronic back pain at its source, according to a new study.

Chronic back pain is often linked to the deterioration of spinal discs and vertebral end plates, which are the thin layers of tissue separating the discs from the vertebrae, according to medical sources.

When these break down, they become porous, allowing nerves that aren’t usually impacted to enter the spinal center, leading to frequent discomfort.

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Research led by Dr. Janet L. Crane at Johns Hopkins University found the parathyroid hormone (PTH) could prevent and even reverse the growth of pain-sensing nerves into damaged areas of the spine.

Parathyroid glands naturally produce PTH, which experts say plays a key role in regulating calcium levels and bone remodeling.

Research suggests a parathyroid hormone can prevent the growth of pain-sensing nerves into damaged areas of the spine. (iStock)

These findings could shift the focus of back pain treatment from managing symptoms to modifying the underlying issue, according to scientists.

“During spinal degeneration, pain-sensing nerves grow into regions where they normally do not exist. Our findings show that parathyroid hormone can reverse this process by activating natural signals that push these nerves away,” Crane said in a press release.

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Synthetic versions of PTH are already used to treat osteoporosis. Earlier research hinted that these treatments might also reduce bone-related pain, but the underlying biological mechanism was not well understood.

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Using animal models, the Johns Hopkins researchers found that one to two months of PTH treatment led to denser, more stable vertebral endplates. 

More significantly, the treatment triggered bone-building cells, known as osteoblasts, to produce a protein called Slit3, the study detailed.

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These findings could shift the focus of back pain treatment from managing symptoms to modifying the underlying issue, according to scientists. (iStock)

The study found that this protein repels growing nerve fibers, preventing them from infiltrating sensitive regions of the spine.

When the researchers removed Slit3 from mice, the hormone’s pain-relieving effects disappeared, confirming the protein’s critical role in the process.

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PTH is already approved by the Food and Drug Administration to treat osteoporosis. Some patients receiving the hormone for bone density have reported unexpected relief from back pain, a phenomenon this study could help explain.

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This study lays a foundation for future clinical trials to explore the efficacy of PTH as a disease-modifying and pain-relieving treatment for spinal degeneration, the researchers say. (iStock)

“Our study suggests that PTH treatment of [lower back pain] during spinal degeneration may reduce aberrant innervation (abnormal nerve growth),” Crane concluded.

The doctor said this research lays the foundation for future clinical trials that will explore PTH’s effectiveness as a disease-modifying and pain-relieving treatment for spinal degeneration.

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Researchers noted several limitations, including the possibility that PTH treatment could affect the central nervous system in ways not fully explored in this study.

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Because the study focused specifically on the Slit3 protein, further research is needed to determine how other genetic factors and bone-forming processes might influence spinal nerve growth and pain relief.

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The study was published in the journal Bone Research.

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Do TikTok Weight-Loss Hacks Like Protein Jell-O Really Work?

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Do TikTok Weight-Loss Hacks Like Protein Jell-O Really Work?


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