Health
New study hints at a hidden Alzheimer’s risk factor affecting older Americans
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People with greater exposure to air pollution could face a higher risk of developing Alzheimer’s disease, according to a new study by Emory University in Atlanta.
Air pollution has previously been established as a risk factor for Alzheimer’s, as well as other chronic conditions, like hypertension, stroke and depression, the researchers noted.
Since those other conditions are themselves linked to Alzheimer’s, the researchers said it’s not yet clear whether air pollution harms brain health on its own, or whether it raises dementia risk by first triggering those other health problems.
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The study, which was published in the journal PLOS Medicine, investigated more than 27.8 million U.S. Medicare recipients, 65 years and older, from 2000 to 2018.
The individuals were examined for level of exposure to air pollution and whether they developed Alzheimer’s, with a focus on other chronic conditions.
Air pollution may have a direct correlation to Alzheimer’s diagnoses, a new study found. (iStock)
Greater exposure to air pollution was associated with an increased risk of Alzheimer’s, which was slightly stronger in people who had experienced a stroke. Hypertension and depression had “little additional impact,” according to the study’s press release.
The authors concluded that air pollution leads to Alzheimer’s mostly through “direct pathways” rather than via other chronic conditions.
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“Our findings suggest that individuals with a history of stroke may be particularly vulnerable to the harmful effects of air pollution on brain health, highlighting an important intersection between environmental and vascular risk factors,” the authors wrote in a statement.
These findings suggest that improving air quality could be “an important way to prevent dementia and protect older adults,” the press release concluded.
Air quality could be “an important way to prevent dementia and protect older adults,” the researchers suggested. (iStock)
Fox News senior medical analyst Dr. Marc Siegel confirmed more studies are revealing that Alzheimer’s is linked to conditions that impact the brain, which can be “sensitive and fragile.”
“Certainly, underlying medical conditions like stroke can lead to this,” Siegel, who was not involved in the study, told Fox News Digital.
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This latest study “does not show cause and effect,” the doctor noted, but rather shows an “increasing association between air pollution and Alzheimer’s, where the particulate matter appears to increase the inflammation in the brain that helps lead to it.”
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“This is another piece in developing a strategy of prevention, early diagnosis and targeted treatments,” Siegel added.
People with a history of stroke could be more susceptible to air pollution risks, according to the researchers. (iStock)
Ozama Ismail, PhD, director of scientific programs at the Alzheimer’s Association in Chicago, agreed that this study adds to existing research on the impact of air pollution and overall health, especially related to the brain.
“Alzheimer’s is a complex disease, and it is likely that there are a variety of factors … that impact a person’s lifetime risk.”
“This is an area of investigation where more research is vital to helping us better understand the connection between pollution and the various factors that cause or contribute to Alzheimer’s disease,” Ismail, who also did not work on the study, told Fox News Digital.
“Previous studies, including those presented at the Alzheimer’s Association International Conference in 2019, 2021 and 2025, have shown evidence for connections between exposure to air pollution and other environmental toxins and risk for Alzheimer’s or other dementias.”
“Avoiding exposure to air pollution is a risk factor that may be easier for some people to change than others,” one expert said. (iStock)
The Lancet Commission on Dementia Prevention added exposure to air pollution to its list of known dementia risk factors in 2020, according to Ismail.
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“We know that Alzheimer’s is a complex disease, and it is likely that there are a variety of factors, in combination, that impact a person’s lifetime risk,” he said. “Avoiding exposure to air pollution is a risk factor that may be easier for some people to change than others.”
Fox News Digital reached out to the study authors for comment.
Health
Common nighttime noise exposure may trigger heart problems, study suggests
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Living near heavy traffic could negatively impact your heart health.
A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.
The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.
Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)
The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.
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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.
The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”
Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)
Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”
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“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.
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“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”
This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.
“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)
“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”
The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”
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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”
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The researcher noted that these findings were consistent across genders, education levels and obesity status.
The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.
Changes in cholesterol levels were more severe than researchers expected. (iStock)
“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”
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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.
“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”
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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”
Experts recommend taking measures to limit traffic noise at night. (iStock)
Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”
“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”
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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.
“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.
Health
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