Connect with us

Health

Man’s blood used to create antivenom for 19 deadly snakes

Published

on

Man’s blood used to create antivenom for 19 deadly snakes

Scientists have developed what they believe is the most widely effective antivenom ever — and the secret ingredient came from one man’s blood.

In the course of their research, the team found a man, Tim Friede, who had been bitten hundreds of times by 16 species of deadly snakes — the poison lethal enough to kill a horse, according to the scientists — over an 18-year period.

Advertisement

Friede had received the bites intentionally as part of a self-immunization process using escalating doses. As a result, he had become “hyper-immune” to the effects of snake neurotoxins, the researchers stated.

POISON FRUIT IN ‘WHITE LOTUS’ COMES FROM ‘SUICIDE TREE’

“After being introduced to Tim Friede and his incredible journey and immune history, we decided there was a once-in-a-lifetime opportunity to study his blood and isolate the basis of a universal antivenom,” lead study author Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, told Fox News Digital. 

The research team found a man, Tim Friede (pictured), who had been bitten hundreds of times by 16 species of deadly snakes over an 18-year period. (Centivax)

Friede agreed to participate in a study in which he donated two blood samples. 

Advertisement

The researchers isolated target antibodies from Friede’s blood that reacted with neurotoxins found within 19 of the world’s deadliest snakes.

EXPOSURE TO TOXIN INCREASES COLORECTAL CANCER RISK AMONG YOUNGER ADULTS, STUDY FINDS

They combined two of the antibodies with another molecule to create a new antivenom. In mouse trials, the antidote was found to be protective against venom from the black mamba, king cobra, coral snakes and tiger snakes, among others.

The results were published on May 2 in the journal Cell Press.

Friede said that by participating in the study, he is “helping humanity.”

Advertisement

The researchers isolated target antibodies from Friede’s blood that reacted with neurotoxins found within 19 of the world’s deadliest snakes. (Centivax)

“I know I am helping someone possibly 8,000 miles away, and that makes me feel really good,” he said in a statement to Fox News Digital. 

“I realize what I’ve been doing over the years hasn’t been in vain with this research.”

“I know I am helping someone possibly 8,000 miles away, and that makes me feel really good.”

“The reason I have been bitten so many times is to get more comfortable with it,” he added. “It became a lifestyle for me, almost like an addiction.”

Advertisement

The hope is that Friede’s “once-in-a-lifetime, unique immune history” could result in a “broad-spectrum” or universal antivenom, according to Glanville.

“If formulated for intramuscular delivery in a ‘venom EpiPen’ form, which is our preference, it could then be deployed more broadly without any IV requirement, including very rural settings or hiker’s backpacks,” he told Fox News Digital.

The researchers now plan to expand the trials to treat dogs that have been brought to veterinary clinics after receiving snake bites, according to the release. 

Scientists combined two of the antibodies with another molecule to create a new antivenom that was found to be protective against poison from the black mamba, king cobra, coral snakes and tiger snakes, among others. (Centivax)

Advertisement

They will also work to create another antivenom to protect against viper bites. 

Prior to this research, the process for making antivenom has been more or less the same over the past century, according to the researchers.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

“Typically, it involves immunizing horses or sheep with venom from single snake species and collecting the antibodies produced,” they wrote. “While effective, this process could result in adverse reactions to the non-human antibodies, and treatments tend to be species and region-specific.”

Approximately 5.4 million people are bitten by snakes each year globally, according to the World Health Organization. Among those, 2.7 million are poisoned by venom, which can cause death or permanent disability. (iStock)

Advertisement

Approximately 5.4 million people are bitten by snakes each year globally, according to the World Health Organization. Among those, 2.7 million are poisoned by venom, which can cause death or permanent disability.

For more Health articles, visit www.foxnews.com/health

The research was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, the National Institutes of Health Small Business Innovation Research program, and the U.S. Department of Energy.

Health

Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns

Published

on

Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns

NEWYou can now listen to Fox News articles!

Americans consume foods every day that are marketed as “healthy,” when they could be quietly destroying their health, one doctor warns.

Dr. Mark Hyman, physician and co-founder of Function Health in California, says that much of America’s daily diet is filled with unhealthy ingredients.

“The amount of refined starches and sugars that are everywhere is just staggering to me, given what we know about how harmful they are,” he shared in an interview with Fox News Digital. “I don’t think people really understand.”

Hyman, author of the new book “Food Fix Uncensored,” said he’s “astounded” by what people are eating, especially for breakfast.

Advertisement

“People just eat sugar for breakfast,” he said. “They have muffins, they have bagels, they have croissants, they have sugar-sweetened coffees and teas.”

Dr. Mark Hyman is the author of the new book “Food Fix Uncensored.” (Function Health; Little, Brown Spark)

In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products, following health trends that encourage eating more protein.

“Highly processed food is not food.”

“Now, we’re seeing this halo of protein in certain things,” Hyman said, mentioning that many protein smoothies are “full of sugar.”

Advertisement

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

The doctor also noted that some popular cereals are now marketed as having protein in them. “My joke is, if it has a health claim on the label, it’s definitely bad for you,” he said.

Instead of starting the day with a “quick fix” or processed food, Hyman suggests choosing whole sources of protein and fat for breakfast, adding that “if there’s a little carbohydrate in there, it’s fine.”

More products marketed as “high protein” have cropped up on supermarket shelves. (iStock)

For his own breakfast, Hyman said he has a protein shake with whey protein, avocado and frozen berries. Eggs and avocados are also a great protein-and-fat combo option, he added.

Advertisement

CLICK HERE FOR MORE HEALTH STORIES

“It’s not that complicated — people need to just think about their breakfast not being dessert,” he said. “No wonder we’re in this cycle of obesity and diabetes. One in three teenage kids now has type 2 diabetes or pre-diabetes. That’s just criminal.”

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

Instead of counting calories and being in a caloric deficit as a way to lose weight and stay healthy, Hyman instead suggests focusing on how certain foods make you feel and how they impact your health.

“When you look at the way in which different types of calories affect your biology, you can just choose what you’re eating, and then you don’t have to worry about how much,” he told Fox News Digital.

Advertisement

In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products. (iStock)

“For example, if you eat a diet that doesn’t cause your insulin to spike — which is low in starch and sugar, higher in protein and fat — you won’t develop those swings in blood sugar, you won’t develop the spikes in insulin, you won’t deposit hungry fat … You will break that cycle.”

People are more likely to “self-regulate when they eat real food” instead of processed foods, which “bypasses the normal mechanisms of satiety, fullness and brain chemistry,” according to Hyman.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

“Ultraprocessed food and junk food or highly processed food is not food,” he said. “It doesn’t support the health and well-being of an organism. It doesn’t do that. It does the opposite.”

Advertisement

Related Article

Food pyramid backlash: Low-fat era may have fueled obesity, diabetes, says doctor
Continue Reading

Health

Scientists make startling discovery when examining prostate cancer tissue

Published

on

Scientists make startling discovery when examining prostate cancer tissue

NEWYou can now listen to Fox News articles!

Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health. 

In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.

The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ. 

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.

Advertisement

In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)

The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.

Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.

NIGHTLY BATHROOM HABIT WAS MISSED SIGN OF COMMON MEN’S CANCER: ‘I DIDN’T KNOW’

The scientists say this is the first direct evidence linking microplastics to prostate cancer.

Advertisement

“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)

The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.

Advertisement

“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”

“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.

Study limitations

Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.

“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.

CLICK HERE FOR MORE HEALTH STORIES

Advertisement

A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”

About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.

The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)

For those concerned about microplastics, Sidransky offered some insights.

“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.

Advertisement

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.

Advertisement

Related Article

Prostate cancer patients see longer survival with new combination drug
Continue Reading

Health

How a Vegan Diet Can Help You Lose Weight 8X Faster

Published

on

How a Vegan Diet Can Help You Lose Weight 8X Faster


Advertisement




How a Vegan Diet Helps You Lose Weight 8X Faster | Woman’s World




















Advertisement





Advertisement


Use left and right arrow keys to navigate between menu items.


Use escape to exit the menu.

Advertisement

Continue Reading

Trending