Health
Man dies hours after eating burger as researchers confirm fatal allergy
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A New Jersey man’s death is the first known to be linked to a tick-borne meat allergy, according to researchers at UVAHealth in Virginia.
The unidentified man, 47, reportedly died last summer, four hours after eating a hamburger and just two weeks after a similar episode triggered by steak.
With the summer episode, the man experienced severe abdominal pain, diarrhea and vomiting after eating the steak, a UVAHealth press release said.
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The incident was initially reported as “sudden unexplained death” until Dr. Thomas Platts-Mills of UVA Health determined the man suffered a fatal allergic reaction.
The findings were published in The Journal of Allergy and Clinical Immunology: In Practice.
A New Jersey man’s death is the first known to be linked to a tick-borne meat allergy, according to researchers at UVAHealth in Virginia. (iStock)
The allergy, alpha-gal syndrome (AGS) — also known as “red-meat allergy” or the “tick bite meat allergy” — is caused by the bite of the Lone Star tick, which is found primarily in Southeastern and Eastern states, according to the Centers for Disease Control and Prevention.
The tick’s saliva contains a sugar molecule called alpha-gal, which is injected into the body with the bite. This triggers allergies to certain types of red meat (primarily pork, beef, rabbit, lamb or venison) or products made from mammals (including cheese, milk, other dairy products and gelatin).
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When people eat any foods containing the allergens, they can experience serious allergy symptoms within a few hours, although some may only have mild reactions.
Symptoms may include rash, nausea and vomiting after eating beef, pork or lamb, according to researchers. Some may also experience itchy or scaly skin; swelling of the lips, face, tongue and throat; and wheezing or shortness of breath, according to Mayo Clinic.
The allergy, alpha-gal syndrome (AGS) — also known as “red-meat allergy” or the “tick bite meat allergy” — is caused by the bite of the Lone Star tick. (iStock)
Although fatal anaphylaxis has been noted as a rare risk in severe cases, the New Jersey man’s death was the first to be attributed to the allergy.
Other factors that may have contributed to his severe reaction, according to Platts-Mills, include a beer he drank with his burger, his exposure to ragweed pollen and recent exercise.
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“The important information for the public is: First, that severe abdominal pain occurring three to five hours after eating beef, pork or lamb should be investigated as a possible episode of anaphylaxis; and, second, that tick bites that itch for more than a week or larvae of ticks often called ‘chiggers’ can induce or increase sensitization to mammalian-derived meat,” Platts-Mills, former chief of UVA Health’s Division of Asthma, Allergy and Clinical Immunology, said in the release.
“On the other hand, most individuals who have mild to moderate episodes of hives can control symptoms with an appropriate diet.”
The tick’s saliva contains a sugar molecule called alpha-gal, which is injected into the body with the bite. This triggers allergies to certain types of red meat. (iStock)
A diagnosis of AGS requires antibody testing and a clinical exam. Many patients face a long road to diagnosis — an average of seven years, according to Dr. Johanna Salzer, CDC epidemiologist and author of a 2023 report on AGS.
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“And to get diagnosed, they have to have access to an allergist,” Salzer previously told Fox News Digital. “For many people, there are barriers to get that level of treatment.”
When someone is diagnosed with AGS, the person may have it for a lifetime.
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“However, for some people, if they remove the foods from their diet that can reactivate alpha-gal syndrome, over time, their antibody levels may drop,” the expert said.
There is no treatment or cure for AGS, though physicians can help patients manage their symptoms.
When people eat any foods containing the allergens, they can experience serious allergy symptoms within a few hours, although some may only have mild reactions. (iStock)
“There are a number of things [that] healthcare providers can provide to alleviate symptoms depending on the patients’ individual reactions,” Salzer said.
“Those with more severe reactions are administered EpiPens in case they go into anaphylactic shock.”
Prevention tips
To protect against tick bites, Salzer recommends applying EPA-approved insect repellent, those containing DEET, picaridin, IR3535, Oil of Lemon Eucalyptus (OLE), para-menthane-diol (PMD) or 2-undecanone, whenever going into an area where tick bites are a possibility.
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Wearing long-sleeved shirts, long pants and socks and avoiding grassy, brushy and wooded areas can also help to prevent bites.
“When returning from an area that is known to have ticks, be sure to shower and do a very thorough check,” Salzer advised.
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Platts-Mills urged doctors and patients who live in areas where Lone Star ticks are common to be aware of the risk.
“More specifically, if they have unexpected episodes of severe abdominal pain occurring several hours after eating mammalian meat, they should be investigated for possible sensitization to the oligosaccharide alpha-gal,” he added.
Fox News Digital reached out to the researchers for comment.
Health
Loneliness may be silently eroding your memory, new research reveals
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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
Health
Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day
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Health
Intermittent fasting’s real benefit may come after you start eating again
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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