Health
James Van Der Beek shared colorectal cancer warning sign months before his death
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Prior to James Van Der Beek’s death at age 48, the actor revealed the first warning sign of his colon cancer — and it’s one that did not seem alarming at the time.
The “Dawson’s Creek” actor’s wife, Kimberly Van Der Beek, confirmed his passing in a social media post on Wednesday.
Following the announcement of his colorectal cancer diagnosis in November 2024, Van Der Beek told Healthline in August that “there wasn’t any red flag or something glaring.”
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“I was healthy. I was doing the cold plunge,” he said. “I was in amazing cardiovascular shape, and I had stage 3 cancer, and I had no idea.”
The one symptom that he did experience was a change in bowel movements, which the actor chalked up to an effect of his coffee consumption.
Prior to James van der Beek’s death at age 48 on Feb. 11, the actor revealed the first warning sign of his from colon cancer. (iStock)
“Before my diagnosis, I didn’t know much about colorectal cancer,” Van Der Beek said. “I didn’t even realize the screening age [had] dropped to 45; I thought it was still 50.”
He ultimately underwent a colonoscopy, which revealed that the actor had stage 3 colon cancer.
COLORECTAL CANCER MAY CAUSE THESE 4 HIDDEN WARNING SIGNS, EXPERTS SAY
Professor Eitan Friedman, M.D., Ph.D., an oncologist and founder of The Suzanne Levy-Gertner Oncogenetics Unit at the Sheba Medical Center in Israel, confirmed that changes in bowel habits are the primary red flag that should raise the suspicion of colorectal cancer.
Others include fatigue (linked to anemia), blood in stool, weight loss, loss of appetite and abdominal discomfort, as Friedman, who has not treated Van Der Beek, previously told Fox News Digital.
“I was in amazing cardiovascular shape, and I had stage 3 cancer, and I had no idea.”
Dr. Erica Barnell, M.D., Ph.D., a physician-scientist at Washington University School of Medicine — and co-founder and chief medical officer at Geneoscopy — noted that Van Der Beek’s experience of having no “glaring” signs is common.
“Many colorectal cancers develop silently, without obvious symptoms,” Barnell, who also did not treat the actor, previously told Fox News Digital. “By the time symptoms appear, the disease may already be advanced.”
The “Dawson’s Creek” actor, 48, who announced his colorectal cancer diagnosis in November 2024, previously told Healthline that initially, “there wasn’t any red flag or something glaring.” (Getty Images)
Symptoms are “especially worrisome” for those 45 and older who have at least one first-degree relative with colon cancer or other GI malignancies, and those with active inflammatory bowel disease, such as ulcerative colitis or Crohn’s disease, added Friedman, who is also an advisory board member at SpotitEarly, a startup that offers an at-home breath test to detect early-stage cancer signals.
Early detection is key
The overall chance of an average-risk person getting colorectal cancer over a lifetime is 4% to 5%, according to Friedman.
“Colonoscopy at age 45 onwards, at five- to 10-year intervals, has been shown to lead to early detection of polyps that have the potential to become malignant, and to allow for their removal as an effective means of minimizing the risk of malignant transformation,” he said.
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Unfortunately, Barnell noted, “screening compliance in the U.S. remains below national targets, and gaps are widest in rural, low-income and minority communities.”
To help close those gaps, she called for greater access to “accurate, noninvasive screening technologies,” along with efforts to increase public awareness.
“Colonoscopy at age 45 onwards, at five- to 10-year intervals, has been shown to lead to early detection of polyps that have the potential to become malignant, and to allow for their removal as an effective means of minimizing the risk of malignant transformation,” an expert said. (iStock)
“Most people don’t like talking about bowel habits, but paying attention to changes can save your life,” Barnell said. “Screening gives us the chance to find problems early — often before you feel sick — and that can make all the difference.”
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Fox News Digital previously reached out to Van Der Beek’s representative for comment.
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Along a bustling sidewalk in Boston, a bright yellow payphone invites folks to “call a Boomer.”
Almost 3,000 miles away in Reno, Nevada, a nearly identical phone prompts residents of Sierra Manor – an apartment complex for seniors – to “Call a Zoomer.” The goal is simple: to get strangers to talk to each other.
The project, often referred to as simply “Call a Boomer,” is the latest initiative from Matter Neuroscience, a New York-based company dedicated to mapping the “biomarkers of happiness.”
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By connecting “two of the loneliest demographics” (older adults and younger adults), the project aims to prove that on a molecular level, “humans need one another in order to be happy,” according to Calla Kessler, a social strategist at Matter Neuroscience.
Along a bustling sidewalk in Boston, a bright yellow payphone invites folks to “Call a Boomer.” (Matter Neuroscience)
“Younger adults and older adults tend to experience the highest levels of loneliness of any age group,” the company wrote on its website. “So the goal of this project is to inspire generational connection through meaningful conversations, despite differences in age, lifestyle or politics.”
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The hope, according to Kessler, is that the calls will shift the brain’s focus from stress to bonding.
“Our neuroscience angle is cannabinoids over cortisol,” Kessler told Fox News Digital. “Cannabinoids are the feel-good neurotransmitter in our brain that creates that warm feeling with a friendship — and when you activate cannabinoids, you’re counteracting the negative effects of cortisol, which is our primary stress hormone.”
“Younger adults and older adults tend to experience the highest levels of loneliness of any age group,” the company noted. (Matter Neuroscience)
This isn’t Matter’s first round of payphones. Its initial experiment connected one of the most liberal cities in the U.S. (San Francisco) with one of the most conservative (Abilene, Texas).
“We basically just wanted people to find common ground and encourage people to think beyond labels,” Kessler said.
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She noted that the negative results were “almost negligible,” with most participants enjoying their time speaking to different people.
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Now, the focus has shifted from political labels to generational divides.
The negative results have beem “almost negligible,” with most participants enjoying their time speaking to different people. (Matter Neuroscience)
As the “Call a Boomer” experiment continues, the team is busy collecting audio files of these intergenerational chats to prove that simple connections with other humans can help improve mental health.
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“Our research is essentially trying to find a non-pharmaceutical cure to depression,” Kessler added.
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Looking ahead, she said, “we’ll definitely be doing fun things that we hope get people’s attention and inspire them to learn a little more about themselves.”
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A New York City father is desperately seeking a donor to save his teenage son’s life.
Max Uribe, now 15 and a high-school freshman, has just weeks until he will need to be hospitalized with a rare blood disorder that could lead to a deadly cancer.
“Max was just 6 when we first noticed there was something wrong with his blood counts,” his father, Juan Uribe, told Fox News Digital. “At the time, we thought it was due to a viral infection, but they never fully recovered back to their normal level.”
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In December 2024, Max’s condition grew worse, and he was diagnosed with clonal cytopenia, a condition involving the blood and bone marrow.
“All three of his blood counts are low — red, white and platelets,” Uribe said.
Max Uribe, pictured with his parents and sister, is in urgent need of a stem cell transplant to save his life. (Uribe Family)
In August 2025, another bone marrow biopsy revealed that Max is on a path to bone marrow failure, creating an urgent need for a stem cell transplant.
“The disease has continued to progress, as his blood counts continue to drop, and therefore, we have to take him to transplant in May of this year,” Uribe said.
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If left untreated, Max’s condition could lead to MDS (myelodysplastic syndrome), a type of blood cancer, and from there possibly into acute myeloid leukemia (AML).
A bone marrow match must have a specific type of HLA (human leukocyte antigen), which are proteins found on the surface of most cells in the body, according to the National Marrow Donor Program (NMDP).
Max Uribe, pictured with his parents, will be hospitalized for a transplant in May, as his blood count has been steadily decreasing. (Uribe Family)
The closer the donor’s HLA markers are to the patient’s, the more likely the body will accept the new cells without a high risk of complications.
People from the same ethnic background are more likely to share similar HLA types, meaning a patient is most likely to find a compatible donor among individuals with similar ancestry, per the NMDP.
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Non-Hispanic White patients have a 79% chance of a perfect match. That drops to 49% for Hispanic/Latino patients, 29% for Black patients and even lower for mixed ancestries, the NMDP reports.
Because Max is a “very rare combination” of half-Colombian from his father and a mix of Italian, British and German from his mother, his path to a perfect match is proving much more difficult, Uribe noted.
“For a kid like Max, with complex, mixed heritage, the math is devastating.”
“For a kid like Max, with complex, mixed heritage, the math is devastating,” he said. “The thinking is, we need large numbers if we’re going to have that perfect match for my son.”
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Max, who participates in competitive tennis and varsity wrestling, just had additional blood work done on Friday, which revealed that his counts continue to plummet.
“We’re at the point where this is beginning to manifest a bit more, which is why the urgency is so critical,” Uribe said.
Because Max is a “very rare combination” of half-Colombian from his father and a mix of Italian, British and German from his mother, his path to a perfect match is proving much more difficult. (Uribe Family)
If a donor is not secured by Max’s hospitalization in May, the medical team will have to proceed with a partial match, which is not ideal for a number of reasons.
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“The survival rate is meaningfully lower with a partial match, and there’s more risk of graft versus host disease (GVHD), which could lead to complications in the process,” Uribe said. With GVHD, the donor cells begin to attack the body.
Max Uribe, an active athlete, is on a path to bone marrow failure, requiring a stem cell transplant. (Uribe Family)
To help prevent this with a partial match, Max would likely need chemotherapy and immunosuppressants for a longer period of time, which could weaken his immune system.
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Anyone interested in donating can order a free test kit on the Team Max website. The kit includes a quick cheek swab that is sent back to the lab to determine whether someone is a match.
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