Health
Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump
In his first months in office, President Trump has slashed funding for medical research, threatening a longstanding alliance between the federal government and universities that helped make the United States the world leader in medical science.
Some changes have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye, a New York Times analysis found. To understand the cuts, The Times trawled through detailed grant data from the National Institutes of Health, interviewed dozens of affected researchers and spoke to agency insiders who said that their government jobs have become unrecognizable.
In all, the N.I.H., the world’s premier public funder of medical research, has ended 1,389 awards and delayed sending funding to more than 1,000 additional projects, The Times found. From the day Mr. Trump was inaugurated through April, the agency awarded $1.6 billion less compared with the same period last year, a reduction of one-fifth. (N.I.H. records for May are not yet comparable.)
The impacts extend far beyond studies on politically disfavored topics and Ivy League universities like Columbia or Harvard. The disruptions are affecting research on Alzheimer’s, cancer and substance use, to name just a few, and studies at public institutions across the country, including in red states that backed Mr. Trump.
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“I think people should know that research that they probably would support is being canceled,” said Eden Tanner, a chemist at the University of Mississippi, who had been working with a colleague at Ohio State University to develop a novel approach for treating glioblastoma, an aggressive form of brain cancer. Their grant had been awarded through a program designed to diversify the biomedical workforce; in April, they were notified that it was being terminated.
“I would like to cure brain cancer,” Dr. Tanner said. “I think that’s not particularly controversial.”
Mr. Trump’s campaign against medical research has been carried out without congressional approval, and the legality is unclear. Lawsuits have challenged the slashing or delaying of funding.
Federal officials, who have accused the N.I.H. of wasteful spending, have attributed the cuts to changing scientific priorities.
The N.I.H. “regularly examines its research portfolio” to determine which projects are “the most meritorious,” Andrew Nixon, a spokesman for the U.S. Department of Health and Human Services, said in an email. “Regular reviews of ongoing activities will help us determine the most strategic balance of projects to support and the best way to manage them going forward, especially as we need to be responsive to the often-changing nature of biomedical scientific progress.”
Scientists fear that the sweeping cuts could do long-term damage to U.S. scientific research, which has long driven medical and financial progress for the nation. “The country is going to be mourning the loss of this enterprise for decades,” said Dr. Harold Varmus, a Nobel Prize-winning cancer biologist who served as the director of the N.I.H. during the Clinton administration and the director of the National Cancer Institute under President Barack Obama.
The federal government has announced the termination of 1,389 awards, with more than $820 million in recent funding.
Publicly announced cancellations
N.I.H. grants, awarded in a competitive process, are typically paid out in installments. A researcher with a $1 million four-year grant, for instance, will get about $250,000 a year. Scientists can use this money to buy equipment and supplies and to pay the salaries of the researchers who work in their labs, among other things.
From 2015 to 2024, there have been fewer than 20 terminations a year, on average, according to Jeremy M. Berg, former director of the National Institute of General Medical Sciences at the N.I.H. from 2003 to 2011. They were generally for extenuating circumstances, such as illness or research misconduct.
But since late February, the government has publicly announced the cancellation of 1,389 N.I.H. awards. The agency scoured grants for key words and phrases like “transgender,” “misinformation,” “vaccine hesitancy” and “equity,” ending those focused on certain topics or populations, according to a current N.I.H. program officer, who asked not to be identified for fear of retribution.
Studies focused on sexual and gender minority groups were among the first on the chopping block.
Katherine Bogen, a doctoral student at the University of Nebraska-Lincoln, had been studying post-traumatic stress, alcohol use and intimate partner violence against bisexual women. The termination notice she received assailed studies “based primarily on artificial and nonscientific categories,” calling such research “antithetical to the scientific inquiry” and alleging that it was “often used to support unlawful discrimination on the basis of race and other protected characteristics, which harms the health of Americans.”
The language was “very insulting,” she said. “I get this letter that tells me, ‘Your research is not science. Not only is it ascientific, it’s a useless drain on resources, and, in fact, your research could be used to discriminate against ‘actual’ Americans or ‘regular’ Americans,’ or whatever they mean.”
The cuts spread to grants on health equity and racial and ethnic groups. Affected projects sought to improve access to mental health care for Latino, low-income and rural communities; to reduce maternal mortality among Black women; and to prevent gun violence in Asian American communities.
Tsu-Yin Wu, a researcher at Eastern Michigan University who led the gun violence project, said that community leaders and study participants were “greatly disappointed” by the grant cancellation. “Some felt betrayed that their voices and engagement no longer matter.”
The agency cut grants for research on vaccine hesitancy, disinformation and misinformation, including a Northeastern University study on cancer misinformation on social media.
It also axed research on Covid-19, including studies that could have helped the nation respond to many infectious disease threats. Among them: a grant to Emory University and Georgia State University, where researchers had developed three potential drugs that showed promise against many RNA-based viruses, including coronaviruses, Ebola, avian influenza and measles, said George Painter, a pharmacologist at Emory who was co-leading the research.
In April, the agency terminated, in part or in whole, more than 350 grants meant to support students, early-career scientists or researchers from groups underrepresented in science. Among these terminations were F31 diversity grants, awarded to Ph.D. students who were members of certain racial or ethnic groups, disabled or from disadvantaged backgrounds.
At the University of Pittsburgh, Luzmariel Medina-Sanchez, who was born and raised in Puerto Rico, and Sierra Wilson, a first-generation college student from Utah, both had their grants canceled. “It’s not even about the work I’m doing,” said Ms. Wilson, who studies how liver cells respond to drug overdoses. “It feels like it’s about me.”
Ms. Medina-Sanchez, who studies how a microbe can help treat celiac disease, said she may leave science altogether. “I feel racially targeted,” she said. “I feel like I’m not going to be a professional in the field of science in America, because obviously my name is Luzmariel.”
(Ms. Wilson and Ms. Medina-Sanchez stressed that they spoke only for themselves and not for the university.)
Delayed funding
In addition to publicly announced cancellations, these are the nearly 1,100 grants that have been delayed, with nearly $740 million in funding.
Besides outright canceling projects, N.I.H. failed to distribute annual payments to more than 1,000 grants, The Times found.
The delays have stifled research on drug discovery, blood vessel health and injury response. In some cases, scientists have cut staff, paused hiring, trimmed back supplies or delayed experiments. Health officials have not explained which projects have been held up, why or for how long.
The Times compiled a list of the delayed grants by searching N.I.H. databases as of June 2 for ones that were funded in 2024 and expected to last beyond 2025, but have not gotten disbursements on schedule.
In the past, annual renewals were routine. Scientists submitted progress reports; the N.I.H. reviewed them and usually continued funding them, occasionally with a week or two of delays. But longer delays have become much more common since Mr. Trump took office.
Joshua Kritzer, a professor of chemistry at Tufts University, investigates the basic science behind potential drug candidates, laying the groundwork for future medications. Most of his lab work is supported by a five-year N.I.H. grant that received $1.4 million over the past two years. But since February, he had been waiting for the third year of expected funding to come in. He slashed purchases of essential supplies and contemplated laying off crucial researchers on his team.
On Tuesday, Kritzer finally received word that his funding had been released, several days after The Times asked federal officials about his and other delayed awards.
“Every week that’s delayed, it’s easily probably three to four weeks to get that research back to where it was,” said Dr. Kritzer, who noted that he was speaking for himself and not for his institution.
Mr. Nixon, the Department of Health spokesman, said that the agency would not discuss deliberations about specific awards but encouraged grant recipients to “speak with the designated N.I.H. officials on their award notice when questions arise.”
In some cases, delays have lasted so long that scientists wondered whether their grants were subject to a “shadow termination.”
The delays stem in part from additional screening for whether the grants align with Trump administration priorities, N.I.H. officials said. Other renewals have been delayed as overstretched N.I.H. staff members work through backlogs in funding. And political appointees are now vetting some projects, too, slowing the process further.
N.I.H. officials said they feared being fired if they processed a grant renewal that the administration disfavored.
In early May, Jon Lorsch, a longtime N.I.H. institute director who was recently promoted to acting deputy director of the agency’s external funding arm, emailed staff members denouncing the renewal of grants “that focused on topics that are not supported under N.I.H./H.H.S.’s priorities,” according to a copy of the email seen by The Times.
“The consequences of approving an award that should not have been approved could be very serious,” he wrote.
But Courtney Griffin, who leads a lab at the Oklahoma Medical Research Foundation and studies blood vessel development and disease, including complications due to diabetes, expressed confusion as to why her expected funding is not coming through. She and her colleagues were making contingency plans and looking for other sources of funding.
“It’s, ironically, a really inefficient use of people’s time to be in this guessing game,” she said, adding that the time could be better spent on biomedical research.
Months-long delays are also affecting new grants that were being vetted when the Trump administration cracked down on grant reviews.
A number of major Alzheimer’s Disease Research Centers, some of which have operated for decades, have waited months for the Trump administration to decide whether to award them fresh five-year grants. The funding gaps have set back ongoing studies and curtailed efforts to take images of patients’ brains, though the N.I.H. has recently told some centers that they would soon receive funding.
“These centers have become a safety valve for people who can’t get a neurology appointment at a private center,” said Dr. Ann Cohen, a co-director of the University of Pittsburgh Alzheimer’s center. Now, she said, things have changed. “There are fewer clinic appointments, fewer opportunities for these individuals to get brain imaging.”
The N.I.H. has also said that it will no longer fund projects in which U.S. researchers distribute some of their money to international partners, throwing the future of many global health projects into question and creating funding delays for ongoing research.
Beyond the disruption of individual projects, other proposed changes could undermine scientific research across the board, experts said. One would sharply curb funding for indirect research costs, such as building maintenance and administrative staff. And then there is Mr. Trump’s proposal to slash the N.I.H.’s total budget by about $18 billion, a cut of almost 40 percent.
A budget cut of that scale would be “truly draconian,” said Dr. Varmus, the former N.I.H. director, who said he hoped Congress would not approve such a sharp reduction. It could leave the agency without enough money to fund promising new work, drive some scientists overseas and prompt some up-and-coming researchers to leave science altogether, he said. “You can completely destroy the system in just a couple of years,” Dr. Varmus said.
Methodology
The Times’s analysis of cancellations is based on the list of terminated grant awards published by the Department of Health and Human Services as of May 30, 2025, and on records from RePORT, the National Institutes of Health’s registry of grants and projects, as of June 2, 2025.
Each circle in the graphics represents a grant award. The circles are sized by the total funding that N.I.H. authorized for each award. H.H.S.’s list of terminations includes a mix of main grant awards, supplements and amendments. The list also indicates a “total amount obligated,” but that figure generally is the total amount awarded to a grant over its lifetime, including any supplements and amendments, rather than the amount for the specific award terminated. The Times’s analysis above uses only the amount authorized for the specific award listed. In some cases, scientists had already spent much of the money they had been awarded before their grants were cancelled, but in others, they lost out on their entire awards. Award amounts and totals — including the year-to-year funding shortfall calculated by The Times — do not include N.I.H. grants administered by the U.S. Department of Veterans Affairs, because their funding amounts are not available in RePORT.
The Times examined cancellations of grants intended to train and support research by groups underrepresented in science. These include the R25 education program; the T32 and T34 training programs; F31 diversity grants; R01 research grants under funding opportunity number PAR-22-241 and research supplements under funding opportunity number PA-23-189, both of which are specifically intended to promote diversity among grant recipients.
To identify grants with delayed funding, Times journalists used information about each grant’s planned duration and prior awards, focusing on those that were eligible for continuation or noncompeting renewal. To account for reporting lags in the RePORTER database, The Times limited this analysis to a time period from Jan. 20 to April 30. The Times excluded grants that appear on H.H.S.’s public list of terminations and grants that have been marked in RePORTER as terminated. Based on interviews and an analysis of historical renewal data, The Times found such grants typically receive a notice of award at roughly the same time each year. Each circle representing a delayed grant is sized by the amount its main award received in fiscal year 2024. This list may include a small number of grants whose renewals are not yet recorded in N.I.H. databases, and others whose renewals are expected to be delayed, because of conversion of grant status for an investigator changing roles or institutions.
To classify each grant’s area of research, The Times extracted the title, the public health relevance statement and the abstract from the N.I.H.’s RePORTER database and ExPORTER files. These fields were used as input for a series of automated prompts to a large language model.
The model generated a brief description of the grant’s research objective. The model also determined if grants were related to research in areas like chronic diseases, vaccines, pandemic preparedness, misinformation, sexual and gender identity, health disparities and certain ethnic and racial groups, and diversity, equity and inclusion initiatives, and then assigned categories.
Times journalists read the projects’ public health relevance statements and abstracts, and they checked the assigned categories for accuracy. They also checked hundreds of grant descriptions and edited them for accuracy and clarity. Only the project descriptions that have been edited by Times journalists are displayed in the article.
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For women over 60, muscle strength plays a critical role in longevity, a new study confirms.
Researchers at the University at Buffalo, New York, followed more than 5,000 women between the ages of 63 and 99, finding that those with greater muscle strength had a significantly lower risk of death over an eight-year period.
The findings were published in JAMA Network Open.
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Muscle function was measured using grip strength and how quickly participants could complete five unassisted sit-to-stand chair raises.
These are two tests commonly used in clinical settings to evaluate muscle function in older adults, the researchers noted.
A recent study shows that stronger muscle strength in women over 60 is linked to a lower risk of death over eight years. (iStock)
“In a community cohort of ambulatory older women, muscular strength was associated with significantly lower mortality rates, even when we accounted for usual physical activity and sedentary time measured using a wearable monitor, gait speed and blood C-reactive protein levels,” study lead author Michael LaMonte, research professor of epidemiology and environmental health at the University at Buffalo, told Fox News Digital.
“Movement is the key — just move more and sit less.”
Many earlier studies did not include those objective measurements, making it difficult to determine whether muscle strength itself was linked to longevity, according to LaMonte. “Our study was able to better isolate the association between strength and death in later life,” he added.
Even for women who don’t get the recommended amount of aerobic physical activity, which is at least 150 minutes per week, muscle strength remained important for longevity, the researchers found.
Women with greater muscle strength were more likely to live longer, even if they did not meet the recommended amount of aerobic exercise. (iStock)
“The findings of lower mortality in those who had higher strength but were not meeting current national guidelines on aerobic activity were somewhat intriguing,” LaMonte said.
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Federal guidelines recommend strengthening activities one to two days per week, targeting major muscle groups.
Resistance training does not have to require a gym membership, LaMonte noted. These exercises can be performed using free weights, resistance bands, bodyweight movements or even household items, such as soup cans.
Experts recommend working major muscle groups one or two days a week using weights, bands or bodyweight exercises. (iStock)
“Movement is the key — just move more and sit less,” he said. “When we can no longer get out of the chair and move around, we are in trouble.”
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LaMonte acknowledged several limitations of the study. The researchers assessed muscle strength in older age but did not explore how earlier levels in adulthood might influence long-term health outcomes.
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“We were not able to understand how strength and mortality relate in younger ages,” he said, noting that future research should explore whether building strength earlier could have an even greater impact on longevity.
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Compounds found in cannabis could provide a new roadmap for treating the world’s most common chronic liver disorder, according to a study released by the Hebrew University of Jerusalem.
The research, published in the British Journal of Pharmacology, found that cannabidiol (CBD) and cannabigerol (CBG) significantly reduced liver fat and improved metabolic health in experimental models.
CBD is the more widely studied non-intoxicating cannabinoid, while CBG is a less common “precursor” cannabinoid from which CBD is formed.
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Unlike THC, the primary psychoactive component in cannabis, these compounds do not produce a “high,” making them viable candidates for long-term medical treatment, the study suggests.
Metabolic dysfunction-associated steatotic liver disease (MASLD) currently affects approximately one-third of the global adult population, according to health data.
Metabolic dysfunction-associated steatotic liver disease (MASLD) currently affects approximately one-third of the global adult population. (iStock)
The condition, which is closely linked to obesity and insulin resistance, has few approved pharmaceutical treatments, the researchers said, leaving patients to rely largely on lifestyle changes that can be difficult to maintain.
“Our findings identify a new mechanism by which CBD and CBG enhance hepatic energy and lysosomal function,” said lead study author Joseph Tam, director of the Multidisciplinary Center for Cannabinoid Research at Hebrew University, in a press release.
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The study highlights a process called “metabolic remodeling,” in which the cannabis compounds created a “backup battery” for the liver by increasing levels of phosphocreatine, a high-energy molecule stored in muscle cells.
This energy reserve helps the organ function under the stress of a high-fat diet, which was an unexpected discovery, the team noted.
Researchers focused on CBD and CBG, two non-psychoactive compounds that offer therapeutic benefits without the “high” associated with THC. (iStock)
The researchers also found that CBD and CBG restored the activity of “cellular cleaning crews” known as cathepsins, enzymes that work within the cell’s recycling centers to break down harmful fats and waste.
With this process, the liver was better able to clear out dangerous lipids, including triglycerides and ceramides, which are known to trigger inflammation, the study showed.
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While both compounds were effective, CBG showed more robust results in certain areas, such as reducing total body fat mass, lowering “bad” LDL cholesterol and improving insulin sensitivity.
Researchers say this study opens a new path for using plant-based compounds to treat metabolic diseases by focusing on how cells manage energy and waste.
The discovery of a phosphocreatine “backup battery” in the liver marks a significant shift in how scientists understand the organ’s ability to survive high-fat diets. (iStock)
Limitations and caveats
Despite the promising results, the research team cautioned that the study was conducted in a controlled experimental environment. Further clinical trials are necessary to determine the proper application for human patients.
Other recent studies have pointed to potential issues with using cannabis as a medical tool.
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A major analysis published in JAMA examined more than 2,500 scientific papers from the last 15 years, including other reviews, clinical trials and guidelines focused on medical marijuana.
The 2025 review highlighted significant gaps between public perception and scientific evidence regarding cannabis’ effectiveness for most medical conditions.
Other recent studies have pointed to issues with the efficacy of cannabis as a medical tool. (iStock)
The researchers concluded that there are very few conditions for which cannabinoid therapies have clear, well-established benefits backed by high-quality clinical data.
“Whenever a substance is widely used, there is likely to be a very wide set of outcomes,” Alex Dimitriu, MD, who is double board-certified in psychiatry and sleep medicine and founder of Menlo Park Psychiatry & Sleep Medicine, previously told Fox News Digital. “This study points to the reality that this widely used substance is not a panacea.”
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The strongest evidence supports FDA-approved cannabinoid medications for treating specific conditions, including HIV/AIDS-related appetite loss, chemotherapy-induced nausea and vomiting, and certain severe pediatric seizure disorders, according to the review.
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Anyone interested in using marijuana for medical purposes should speak to a healthcare provider to discuss potential risks and benefits.
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While cannabis has recently come under fire for potential negative health risks, a recent study suggests that its use could increase brain volume and cognitive fitness.
Researchers at the University of Colorado Anschutz Medical Campus analyzed cannabis usage, brain scans and cognitive test results for more than 26,000 adults between the ages of 40 and 77, using data from the UK biobank.
The study found that cannabis users — particularly those who reported moderate lifetime usage — showed larger volumes in several brain regions.
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“Compared to individuals with no history of cannabis use, those who reported using cannabis showed larger volumes in several brain regions characterized by a high density of cannabinoid (CB1) receptors — regions involved in processes such as memory, information processing and emotion regulation,” lead study author Anika Guha, Ph.D., a researcher at the University of Colorado Anschutz Medical Campus, told Fox News Digital.
A recent study suggests that cannabis use could increase brain volume and cognitive fitness. (iStock)
The cannabis users also scored better on cognitive tests that measured learning, processing speed and executive function.
This outcome differs from many previous studies, which have focused on short-term cognitive impairment during or shortly after cannabis use, the researcher pointed out.
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“These findings suggest that the relationship between cannabis and the brain may differ across the lifespan, and that moderate use in mid-to-later adulthood may be associated with positive brain health outcomes,” Guha said.
Not all areas of the brain showed positive effects among cannabis users. The posterior cingulate, which is involved in self-reflection and memory, had lower volume with higher marijuana use.
“The takeaway is not that people should start using more cannabis based on these findings alone.”
As cannabis has been rising in popularity among all ages, this type of study is important for understanding its long-term effects and the pros and cons of use, according to Matt Glowiak, Ph.D., chief addiction specialist with Recovered, an organization that provides information and resources for mental health and addiction treatment.
The drug’s effects likely depend on factors such as age, dose, frequency, product composition and individual vulnerability. (AP Photo/Martin Meissner, File)
“Given the connection between cannabis use and larger brain volume, it is believed that it may help [older] individuals retain cognitive function that might otherwise naturally decline,” Chicago-based Glowiak, who was not involved in the study, told Fox News Digital.
“This is a huge benefit, but one we need to explore a bit further, ahead of encouraging those who would otherwise not consider integrating cannabis into their healthcare regimen.”
Limitations and caveats
As the study was observational in nature, it could not prove that cannabis use improves brain health — instead, it only showed an association, according to Dr. Marc Siegel, Fox News senior medical analyst, who was not involved in the study.
“The preponderance of previous evidence does not line up with improved cognitive function from chronic cannabis use,” Siegel told Fox News Digital. “This study is an outlier, and though it cannot be ignored, it is not justification for use.”
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The study also relied on the UK Biobank, which offers a “large and rich dataset,” Guha said — but it is limited to the questions that were originally posed to the participants.
“In particular, we have only a broad measure of how many times someone has used cannabis over their lifetime,” she said. “We do not have access to details about how they used cannabis, such as whether they smoked or used edibles, the type or potency of cannabis, or when in their life they used most heavily.”
Cannabis users scored better in learning, processing speed and executive function. (iStock)
“Those details likely matter a great deal for understanding how cannabis affects the aging brain.”
Given these limitations, Guha suggests that the findings should be seen as an early indicator that cannabis use may be related to brain aging, “and as a starting point for more targeted research that can tease apart these relationships.”
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“The takeaway is not that people should start using more cannabis based on these findings alone,” she emphasized. “While cannabis may have potential benefits in some contexts, a substantial body of research also documents important risks, underscoring that cannabis is neither completely beneficial nor completely harmful.”
The drug’s effects likely depend on factors such as age, dose, frequency, product composition and individual vulnerability, according to Guha.
“Given the widespread use and legalization of cannabis, it would be great to know that it is net-positive for brain health — however, this feels too good to be true, and too early to claim,” one expert said. (AP)
“As with any substance, individuals should consult with a healthcare provider before initiating use, particularly if they have a history of mental health concerns, as THC (the primary psychoactive component of cannabis) can exacerbate symptoms such as psychosis in vulnerable individuals,” she added.
Dr. Alex Dimitriu, who is double board-certified in psychiatry and sleep medicine and the founder of Menlo Park Psychiatry & Sleep Medicine, reiterated that this study is an “outlier,” as most previous research has shown “detrimental effects” from cannabis use.
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“Given the widespread use and legalization of cannabis, it would be great to know that it is net-positive for brain health — however, this feels too good to be true, and too early to claim,” he said. “I would advise proceeding with caution and moderation.”
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Dimitriu agreed that more large-scale studies and review papers are needed to get a “clearer picture.”
“What this cannabis study shows is that there may be conflicting information, which warrants more investigation.”
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