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Hair loss and prostate medication could also reduce heart disease risk, study finds

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Hair loss and prostate medication could also reduce heart disease risk, study finds

A drug that has long been used to treat two common men’s health conditions could have some unexpected benefits.

Finasteride — more commonly known as Propecia or Proscar — has treated male pattern baldness and enlarged prostate in millions of men.

In a recent study, researchers from the University of Illinois Urbana-Champaign have also linked the “miracle drug” to cholesterol-lowering effects and reduced heart disease risk.

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The findings, published in the Journal of Lipid Research, showed lower cholesterol levels among men who took the drug — on average, 30 points less than men who were not on the medication.

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The data was initially collected as part of the National Health and Nutrition Examination Survey between 2009 and 2016. 

A drug that has long been used to treat two common men’s health conditions could have some unexpected benefits. (iStock)

Then, in a study of mice, use of the drug for 12 weeks — along with a high-fat, high-cholesterol “Western” diet — was linked to reduced cholesterol, slower buildup of plaque in the arteries and reduced liver inflammation, among other benefits. 

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“The most surprising finding was the human data,” lead study author Jaume Amengual, assistant professor in the Department of Food Science and Human Nutrition and the Division of Nutritional Sciences at the University of Illinois, told Fox News Digital. 

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“When we observed the association with finasteride and plasma lipids, we decided to do our mouse study.”

Drug’s benefits and side effects

As a hair loss treatment, finasteride works by blocking a protein found in hair follicles — and as an enlarged prostate treatment, the drug blocks the prostate gland that activates testosterone.

Atherosclerosis, which occurs when cholesterol plaques build up in the arteries and increase the risk of heart attack and stroke, is most prevalent among men.

As a hair loss treatment, finasteride works by blocking a protein found in hair follicles. (iStock)

Some experts have linked the male hormone testosterone to the heart condition.

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The potential hormonal effect prompted the researchers to explore whether the medication could also reduce heart disease risk, Amengual said.

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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, was not involved in the study but commented on the implications of finasteride.

“It stops testosterone from turning into dihydrotestosterone and thereby stops hair loss and also shrinks the prostate by 25%,” he said.

Side effects can include depression, anxiety and impotence, the doctor added.

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In response to the drug being found to lower cholesterol and decrease heart disease risk, a doctor called for more research to confirm the findings. (iStock)

Dr. Brett Osborn, a Florida neurologist and longevity expert who was also not involved in the study, offered his insights on the uses and risks associated with the drug.

“Finasteride in normal dosages — 1 to 5 mg daily, depending upon the indication — has intolerable side effects in many,” he said.

“Finasteride in normal dosages has intolerable side effects in many.”

The drug works by lowering levels of DHT (dihydrotestosterone) in order to have the desired effect on the prostate gland and hair follicles, he said, “but it can also strip a man of his energy, virility, libido and motivation.”

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Study limitations and next steps

The study did have some limitations, the researchers noted.

Out of nearly 4,800 total participants, only 155 were finasteride users, all of whom were men over 50. The survey also did not determine the duration or amount of the doses.

As an enlarged prostate treatment, finasteride blocks the prostate gland that activates testosterone. (iStock)

“We also did not examine the effects of finasteride in women or female mice,” Amengual said. 

“However, this drug is not prescribed for women, as it could be dangerous during pregnancy.”

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“This drug could be another tool in the fight against cardiovascular diseases.”

The next step is to track cholesterol levels of patients taking finasteride or to launch a clinical trial to confirm the link.

“There is still so much to discover on how finasteride works in our body,” Amengual noted. “But based on our findings, this drug could be another tool in the fight against cardiovascular diseases.”

The drug works by lowering levels of DHT (dihydrotestosterone) in order to have the desired effect on the prostate gland and hair follicles, which can cause side effects in some men, a doctor noted. (iStock)

In response to the drug being found to lower cholesterol and decrease heart disease risk, Siegel also called for more research.

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“Much larger studies are needed in humans to confirm these findings before you would ever consider using this drug for cardioprevention,” he said.

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“It may end up being useful for this purpose in the elderly, who are at higher risk of heart attacks and strokes, as an add-on statin therapy.”

In addition to the study’s small size, Osborn noted that it was performed retrospectively — “meaning there was no control group(s), and that random effects, unbeknownst to the researchers, may have swayed the results in one direction,” he told Fox News Digital. 

Dr. Marc Siegel, left, and Dr. Brett Osborn both shared insights on finasteride’s uses and side effects. (Dr. Marc Siegel | Dr. Brett Osborn)

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“That said, the authors’ observations are interesting and demand further investigation,” Osborn went on. 

“After all, lipid-lowering agents are one of the mainstays of cardiovascular risk reduction — and most Americans die vascular deaths.”

This study doesn’t mean that every male should start taking finasteride, Osborn cautioned.

Instead, he recommends getting regular exercise, increasing daily fiber intake to 25 grams and taking high doses of omega-3 fatty acids to reduce cardiovascular risk.

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“For now, skip the finasteride as a lipid-lowering agent,” he advised. “As it stands now, the juice isn’t worth the squeeze.”

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Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns

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Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns

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Americans consume foods every day that are marketed as “healthy,” when they could be quietly destroying their health, one doctor warns.

Dr. Mark Hyman, physician and co-founder of Function Health in California, says that much of America’s daily diet is filled with unhealthy ingredients.

“The amount of refined starches and sugars that are everywhere is just staggering to me, given what we know about how harmful they are,” he shared in an interview with Fox News Digital. “I don’t think people really understand.”

Hyman, author of the new book “Food Fix Uncensored,” said he’s “astounded” by what people are eating, especially for breakfast.

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“People just eat sugar for breakfast,” he said. “They have muffins, they have bagels, they have croissants, they have sugar-sweetened coffees and teas.”

Dr. Mark Hyman is the author of the new book “Food Fix Uncensored.” (Function Health; Little, Brown Spark)

In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products, following health trends that encourage eating more protein.

“Highly processed food is not food.”

“Now, we’re seeing this halo of protein in certain things,” Hyman said, mentioning that many protein smoothies are “full of sugar.”

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The doctor also noted that some popular cereals are now marketed as having protein in them. “My joke is, if it has a health claim on the label, it’s definitely bad for you,” he said.

Instead of starting the day with a “quick fix” or processed food, Hyman suggests choosing whole sources of protein and fat for breakfast, adding that “if there’s a little carbohydrate in there, it’s fine.”

More products marketed as “high protein” have cropped up on supermarket shelves. (iStock)

For his own breakfast, Hyman said he has a protein shake with whey protein, avocado and frozen berries. Eggs and avocados are also a great protein-and-fat combo option, he added.

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“It’s not that complicated — people need to just think about their breakfast not being dessert,” he said. “No wonder we’re in this cycle of obesity and diabetes. One in three teenage kids now has type 2 diabetes or pre-diabetes. That’s just criminal.”

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Instead of counting calories and being in a caloric deficit as a way to lose weight and stay healthy, Hyman instead suggests focusing on how certain foods make you feel and how they impact your health.

“When you look at the way in which different types of calories affect your biology, you can just choose what you’re eating, and then you don’t have to worry about how much,” he told Fox News Digital.

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In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products. (iStock)

“For example, if you eat a diet that doesn’t cause your insulin to spike — which is low in starch and sugar, higher in protein and fat — you won’t develop those swings in blood sugar, you won’t develop the spikes in insulin, you won’t deposit hungry fat … You will break that cycle.”

People are more likely to “self-regulate when they eat real food” instead of processed foods, which “bypasses the normal mechanisms of satiety, fullness and brain chemistry,” according to Hyman.

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“Ultraprocessed food and junk food or highly processed food is not food,” he said. “It doesn’t support the health and well-being of an organism. It doesn’t do that. It does the opposite.”

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Scientists make startling discovery when examining prostate cancer tissue

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Scientists make startling discovery when examining prostate cancer tissue

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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health. 

In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.

The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ. 

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.

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In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)

The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.

Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.

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The scientists say this is the first direct evidence linking microplastics to prostate cancer.

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“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)

The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.

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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.

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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”

“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.

Study limitations

Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.

“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.

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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”

About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.

The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)

For those concerned about microplastics, Sidransky offered some insights.

“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.

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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”

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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.

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How a Vegan Diet Can Help You Lose Weight 8X Faster

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How a Vegan Diet Can Help You Lose Weight 8X Faster


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How a Vegan Diet Helps You Lose Weight 8X Faster | Woman’s World




















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