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FDA approves new drug for Alzheimer’s disease: ‘Meaningful results’

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FDA approves new drug for Alzheimer’s disease: ‘Meaningful results’

The U.S. Food and Drug Administration (FDA) has approved a new medication for people with Alzheimer’s disease

Eli Lilly’s Kisunla (donanemab) is a once-monthly injection intended for adults with early symptomatic Alzheimer’s disease, according to a press release from the company.

Eligible patients include those with mild cognitive impairment (MCI) and those who have mild dementia with confirmed amyloid pathology.

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This is the first medication to target amyloid plaques — the proteins that build up in the brains of Alzheimer’s patients, often impairing memory and cognitive function — with evidence to support stopping therapy when amyloid plaques are removed, the release stated.

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The U.S. Food and Drug Administration (FDA) has approved a new medication for people with Alzheimer’s disease.  (iStock)

“Kisunla demonstrated very meaningful results for people with early symptomatic Alzheimer’s disease, who urgently need effective treatment options,” said Anne White, executive vice president and president of Lilly Neuroscience, Eli Lilly and Company, in the release.

“We know these medicines have the greatest potential benefit when people are treated earlier in their disease, and we are working hard in partnership with others to improve detection and diagnosis.”

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Fox News Digital reached out to the company for further comment.

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The drug is designed to remove excessive buildup of amyloid plaques and slow cognitive decline, according to the company.

Eli Lilly’s Kisunla (donanemab) is a once-monthly injection intended for adults with early symptomatic Alzheimer’s disease. (Eli Lilly & Company)

The approval follows an advisory panel’s recommendation of the drug at the FDA’s Peripheral and Central Nervous System Advisory Committee hearing last month.

At that hearing, Eli Lilly officials presented clinical trial results that showed the drug slowed cognitive and functional decline for people with mild cognitive impairment due to early stages of Alzheimer’s.

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In phase 3 trials published in May 2023, donanemab was shown to “significantly slow cognitive and functional decline in people with early symptomatic Alzheimer’s disease,” according to a press release on Eli Lilly’s website.

In phase 3 trials published in May 2023, donanemab was shown to “significantly slow cognitive and functional decline in people with early symptomatic Alzheimer’s disease,” according to a press release on Eli Lilly’s website. (iStock)

That study was published by the Journal of the American Medical Association.

The most serious potential side effect of Kisunla is amyloid-related imaging abnormalities (ARIA), which can lead to temporary brain swelling or bleeding.

                  

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Although this effect “usually resolves over time,” it can be life-threatening, the company said.

Some patients may also experience headaches or potentially serious allergic reactions during or shortly after the drug’s infusion.

A doctor points out evidence of Alzheimer’s disease on PET scans at the Center for Alzheimer Research and Treatment at Brigham And Women’s Hospital in Boston, Massachusetts.  (REUTERS/Brian Snyder/File Photo)

Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, who was not involved in the drug trials, noted that donanemab is very similar to Leqembi, the current drug on the market that blocks amyloid formation.

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Denonemab is “somewhat more effective,” Siegel noted, as it slows the progression of Alzheimer’s by about 35% versus 27% for Leqembi.

“It may be better at removing plaques,” he said.

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The Best Time To Take ‘Nature’s Ozempic’ Berberine for Weight Loss and Blood Sugar Control, According to an MD

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The Best Time To Take ‘Nature’s Ozempic’ Berberine for Weight Loss and Blood Sugar Control, According to an MD


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Study reveals why chewing gum might actually help with focus and stress relief

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Study reveals why chewing gum might actually help with focus and stress relief

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Humans have been chewing gum for thousands of years, long after the flavor fades and without any clear nutritional benefit.

The habit dates back at least 8,000 years to Scandinavia, where people chewed birchbark pitch to soften it into a glue for tools. Other ancient cultures, including the Greeks, Native Americans and the Maya, also chewed tree resins for pleasure or soothing effects, National Geographic recently reported.

In the late 19th and early 20th centuries, William Wrigley Jr. transformed chewing gum from a novelty into a mass consumer habit through relentless and innovative marketing. His brands, including Juicy Fruit and Spearmint, promoted gum as a way to calm nerves, curb hunger and stay focused.

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“Are you worried? Chew gum,” an article from 1916 said, according to Kerry Segrave’s book, “Chewing Gum in America, 1850-1920: The Rise of an Industry.” “Do you lie awake at night? Chew gum,” it continued. “Are you depressed? Is the world against you? Chew gum.”

Advertisements have long framed chewing gum as a tool for stress relief and mental sharpness. (Keystone View Company/FPG/Archive Photos/Getty Images)

In the 1940s, a study found chewing resulted in lower tension but couldn’t say why. 

“The gum-chewer relaxes and gets more work done,” The New York Times wrote at the time about the study’s results.

Gum became an early form of wellness, and companies are trying to revive that idea today as gum sales decline, according to National Geographic.

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But only now are scientists finally beginning to understand the biology behind those long-standing beliefs.

Chewing gum may briefly affect attention and stress-related brain activity, according to studies. (iStock)

A 2025 review by researchers at the University of Szczecin in Poland analyzed more than three decades of brain-imaging studies to examine what happens inside the brain when people chew gum. Using MRI, EEG and near-infrared spectroscopy research, the authors found that chewing alters brain activity in regions tied to movement, attention and stress regulation.

The findings help clarify why the seemingly pointless task can feel calming or focusing, even once the flavor has faded.

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Chewing gum activated not only the brain’s motor and sensory networks involved in chewing, but also higher-order regions linked to attention, alertness and emotional control, the review found. EEG studies found brief shifts in brain-wave patterns linked to heightened alertness and what researchers call “relaxed concentration.”

Humans have chewed gum for pleasure for thousands of years, according to reports. (iStock)

“If you’re doing a fairly boring task for a long time, chewing seems to be able to help with concentration,” Crystal Haskell-Ramsay, a professor of biological psychology at Northumbria University, told National Geographic.

The review also supports earlier findings that gum chewing can ease stress, but only in certain situations. In laboratory experiments, people who chewed gum during mildly stressful tasks such as public speaking or mental math often reported lower anxiety levels than those who didn’t.

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Chewing gum did not, however, consistently reduce anxiety in high-stress medical situations, such as immediately before surgery, and it offered no clear benefit when participants faced unsolvable problems designed to induce frustration.

Some studies suggest chewing gum can reduce stress in mild situations but not extreme ones. (iStock)

Across multiple studies, people who chewed gum did not remember lists of words or stories better than those who didn’t, the researchers also found, and any boost in attention faded soon after chewing stopped.

Gum may simply feed the desire to fidget, experts suspect.

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“Although these effects are often short-lived, the range of outcomes … underscores chewing gum’s capacity to modulate brain function beyond simple oral motor control,” the researchers wrote.

“However, at this time, the neural changes associated with gum chewing cannot be directly linked to the positive behavioral and functional outcomes observed in studies,” they added.

A 2025 review analyzed decades of MRI, EEG and near-infrared spectroscopy studies on gum chewing. (iStock)

Future research should address longer-term impacts, isolate flavor or stress variables and explore potential therapeutic applications, the scientists said.

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The findings also come with caveats beyond brain science. Although sugar-free gum may help reduce cavities, Fox News Digital has previously reported that dentists warn acids, sweeteners and excessive chewing may harm teeth or trigger other side effects.

Fox News Digital has reached out to the study’s authors for comment.

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The Best Time To Take Turmeric for Weight Loss and How To Maximize Results

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The Best Time To Take Turmeric for Weight Loss and How To Maximize Results


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