Health
Aging-related joint disorder increasingly affects people under 40, study finds
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Cases of gout are rising in younger individuals, according to a global study.
The condition, which is a type of inflammatory arthritis, steadily increased in people aged 15 to 39 between 1990 and 2021, researchers in China announced.
Although rates vary widely between countries, the total number of young people with the condition is expected to continue rising through 2035.
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The study, published in the journal Joint Bone Spine, investigated 2021 data from the Global Burden of Disease (GBD), spanning 204 countries within the 30-year timeframe.
The data measured gout prevalence, incidence and years lived with disability, tracking global trends over time. The results showed a global increase across all three outcomes.
Gout is expected to continue rising in young people through 2035. (iStock)
Prevalence and disability years increased by 66%, and incidence rose by 62%. In 2021, 15- to 39-year-olds accounted for nearly 14% of new gout cases globally, the study found.
Men from 35 to 39 years old and people in high-income regions had the highest burden, but high-income North America topped the list for highest rates.
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Men were also found to have lived more years with gout due to high BMI, while women tended to have the condition as a link to kidney dysfunction, the study noted.
The total number of cases is expected to increase globally due to population growth, but the study projected that rates per population would decrease.
The researchers noted that data quality, especially in low-income settings, could have posed a limitation to the broad GBD data.
What is gout?
Gout is a common form of arthritis involving sudden and severe attacks of pain, swelling, redness and tenderness in the joints, according to Mayo Clinic. It most often occurs in the big toe.
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The condition occurs when urate crystals accumulate in the joint. These form when there are high levels of uric acid in the blood, which the body produces when it breaks down a natural substance called purines.
A gout flare-up can happen at any time, often at night, causing the affected joint to feel hot, swollen, tender and sensitive to the touch.
Urate crystals, described as sharp and needle-like, build up in the joint, causing intense pain and swelling. (iStock)
Purines can also be found in certain foods, like red meat or organ meats like liver and some seafood, including anchovies, sardines, mussels, scallops, trout and tuna, according to the Mayo Clinic. Alcoholic drinks, especially beer, and drinks sweetened with fruit sugar can also lead to higher uric acid levels.
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Uric acid will typically dissolve in the blood and pass through the kidneys into urine, but when the body produces too much or too little uric acid, it can cause a build-up of urate crystals. These are described by the Mayo Clinic as sharp and needle-like, causing pain, inflammation and swelling in the joint or surrounding tissue.
Risk factors for gout include a diet rich in high-purine foods and being overweight, which causes the body to produce more uric acid and the kidneys to have trouble eliminating it.
Experts urge patients to seek medical attention for gout flare-ups. (iStock)
Certain conditions like untreated high blood pressure, diabetes, obesity, metabolic syndrome and heart and kidney diseases can increase the risk of gout, as well as certain medications.
A family history of gout can also increase risk. Men are more likely to develop the condition, as women tend to have lower uric acid levels, although symptoms generally develop after menopause.
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Untreated gout can cause worsening pain and joint damage, experts caution. It may also lead to more severe conditions, such as recurrent gout, advanced gout and kidney stones.
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The Mayo Clinic advises patients to seek immediate medical care if a fever occurs or if a joint becomes hot and inflamed, which is a sign of infection. Certain anti-inflammatory medications can help treat gout flares and complications.
Fox News Digital reached out to the researchers for comment.
Health
Drug-soaked paper is killing inmates amid reports of prison smuggling trends
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A dangerous drug smuggling trend has been reported among U.S. jails and prisons, highlighting a growing health risk.
Synthetic cannabinoids have been increasingly detected in fatal overdoses among incarcerated individuals, according to a recent alert from The Center for Forensic Science Research & Education (CFSRE).
These man-made psychoactive substances are designed to mimic the effects of THC, the primary active component of cannabis.
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Reports have also revealed that synthetic cannabinoids are increasingly being smuggled into correctional facilities on common paper items, such as letters, greeting cards, books, postcards and magazines.
The CFSRE has previously warned of “drug-soaked paper strips” causing overdoses among incarcerated individuals.
A dangerous drug smuggling trend has been reported among U.S. jails and prisons, highlighting a growing health risk. (iStock)
In many cases, the papers are laced with a “potpourri” of synthetic cannabinoids mixed with other dangerous drugs, officials noted.
“While it’s impossible to know exactly why people are cooking up these combinations, I suspect they are simply ordering these substances from China or India and mixing them with very little understanding of how different substances interact or what constitutes a lethal dose,” Alex Krotulski, director of toxicology and chemistry for the CFSRE, told a local outlet.
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In a December 2024 study, the CFSRE found that the paper strips it examined primarily contained “synthetic cannabinoid receptor agonists, nitazene opioids, and other novel psychoactive substances.”
The drug-laced papers have been found to cause “severe health outcomes,” including central nervous system depression (slowed brain activity) and bradycardia (slowed heart rate), the agency stated.
In many cases, the papers are laced with a “potpourri” of synthetic cannabinoids mixed with other dangerous drugs, officials noted. (iStock)
Cook County Jail in Chicago, which houses nearly 5,000 detainees, has reported increasing cases of smugglers soaking paper with synthetic drugs and sending them into the jail through mail or visitors.
In 2023, the jail’s administration confirmed 18 total deaths of prisoners in custody. Five of those were caused by overdose, with three involving synthetic cannabinoids, according to Cook County Medical Examiner records.
“I cannot stress how serious this is,” Dr. Priscilla Ware, who oversees Cook County Correctional Health and is medical director of Cermak Health Services, told a local outlet in November 2023. “People are dying from this product every single day when they use it.”
“I cannot stress how serious this is.”
To address the growing trend of soaking paper with cannabinoids, the jail’s administrators reportedly implemented a ban on paper in April 2023.
In 2024, Cook County Sheriff Tom Dart told a local outlet that while overdose deaths were lower that year, drug-soaked paper smuggling continues to be an issue.
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“Unfortunately, it has been common to see test results for drug-soaked paper come back with two or three dangerous drugs, and we know that the people who produce this paper often included toxic chemicals, such as insecticides and rat poison, in their ‘recipes,’” Dart told the outlet.
“That was alarming enough. But to see these results come back with a half dozen or more dangerous synthetic drugs – any one of which could be fatal on its own – is terrifying.”
Cook County Jail in Chicago (not pictured), which houses nearly 5,000 detainees, has reported increasing cases of smugglers soaking paper with synthetic drugs and sending them into the jail through mail or visitors. (iStock)
In July 2024, Cook County reportedly seized three pieces of paper that were suspected to be laced with drugs. Testing by CFSRE found that the papers contained up to 10 separate dangerous synthetic drugs, including protonitazene (a synthetic opioid up to three times more powerful than fentanyl) and xylazine (a powerful animal sedative known as “tranq” or “zombie drug”).
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Cook County noted in an August 2024 press release that drug-laced papers have been known to sell for $10,000 per page.
The issue appears to extend beyond Chicago, as The New York Times has reported that at least 16 states have prosecuted people for smuggling drug-laced papers into jails and prisons.
“It represents a broader and very troubling shift in how highly potent synthetic drugs are being distributed, concealed and consumed across multiple settings,” one addiction specialist said. (iStock)
“Drug‑soaked paper allows extremely powerful substances — synthetic cannabinoids, opioids and other novel compounds — to be delivered invisibly, without smell or obvious residue, making detection difficult in many environments,” Dr. Adam Scioli, chief medical officer of Caron Treatment Centers in Pennsylvania, told Fox News Digital.
Scioli said the “drug‑impregnated paper” should not be viewed as a problem limited to prisons.
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“It represents a broader and very troubling shift in how highly potent synthetic drugs are being distributed, concealed and consumed across multiple settings,” he said. “The same delivery method can easily affect schools, mail rooms, shelters, treatment centers and private homes — any place where paper moves freely and inspection is limited.”
The fact that paper can be handled or shared unintentionally raises the risk not only of overdose, but of accidental exposure to staff, family members or bystanders, Scioli cautioned.
“The same delivery method can easily affect schools, mail rooms, shelters, treatment centers and private homes.”
To reduce accidental exposure and to protect both the public and frontline workers, Scioli calls for early detection and screening tools.
“Expanding access to evidence‑based addiction treatment, including medications for opioid and alcohol use disorder, directly lowers demand for illicit and high‑risk substances,” he added.
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“A coordinated response that includes healthcare, public safety, mail systems and community education is essential — this cannot be solved by enforcement alone.”
Fox News Digital reached out to Cook County Jail requesting comment.
Health
How To Quiet Food Noise Fast and Make Weight Loss After 50 Easier
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Health
Drinking habits of parents may be more contagious than they think: ‘Greater risk’
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Parents’ drinking habits really do rub off on their children, a new study suggests.
Specific parenting interventions can break the cycle of generational substance use, even if the parents don’t stop drinking themselves, according to researchers from the Federal University of São Paulo.
The study analyzed data from more than 4,200 Brazilian teens and their guardians, finding that parents’ drinking habits are a leading predictor of whether their teenagers will partake in alcohol or drugs.
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A parent’s alcohol consumption is associated with a 24% probability of their child drinking — and that risk escalates when multiple substances are involved, according to the study’s press release.
When guardians use both alcohol and tobacco or vapes, the likelihood of their children following suit jumps to 28%. The findings were published in the scientific journal Addictive Behaviors.
Parents’ alcohol consumption is associated with a 24% probability of their child drinking, and that risk escalates when multiple substances are involved. (iStock)
The data was collected from 2023 to 2024 in four towns in Brazil. The average age of the adolescents was 14.7 years, and the group included an even mix of boys and girls.
“With this study, we reinforce the fact that parents’ patterns of alcohol and other drug use influence their children’s,” said lead author Zila Sanchez, a professor at the university, in the release.
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The most effective form of prevention appears to be lead-by-example abstinence.
When guardians opt not to drink, 89% of adolescents refrain from using alcohol or other drugs.
When guardians opt not to drink, 89% of adolescents refrain from using alcohol or other drugs. (iStock)
Home environment also played a role in adolescent substance use, as the researchers analyzed the effects of the following four parenting styles.
- Authoritative: High affection mixed with clear rules (most effective)
- Authoritarian: Strict rules but low affection (reduced drug use, but was less effective against alcohol)
- Permissive: High affection but no rules (offered no protective effect)
- Neglectful: Low affection and no rules (offered no protective effect)
“If they set rules and limits at home and show affection, these protective factors greatly minimize the risk they themselves pose when they consume these substances,” Sanchez said.
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However, the researchers warned that affection isn’t a cure-all, and that if alcohol is framed as a universal coping mechanism, a teenager is far more likely to adopt that behavior.
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“When consumption is frequent and treated as something trivial, it translates into greater risk, regardless of the existing emotional bond,” Sanchez said.
While a parent’s habits are the leading predictor of teen use, setting firm house rules can significantly minimize the risk, the study suggested. (iStock)
The researchers noted some limitations of the study.
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Because it analyzed a snapshot of data from one point in time, it shows a connection but cannot prove that parents’ drinking caused the teens’ choices.
The data also relied on surveys from teenagers, who may have underreported their own use or misremembered their parents’ habits.
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Additionally, because the study focused only on four towns in Brazil, the results may not reflect drinking cultures or family dynamics in other parts of the world.
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