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4 anti-aging approaches revealed in 2025 that may help Americans live longer

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4 anti-aging approaches revealed in 2025 that may help Americans live longer

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On average, Americans want to live to be 91 years old, according to a recent Pew Research survey — a goal that has driven a focus on longevity-boosting practices.

Over 60% of U.S. adults use supplements and most prioritize long-term health and wellness behaviors as part of an anti-aging approach, research has shown.

In 2025, researchers revealed the following anti-aging discoveries that may help you live a longer life.

COMMON DAILY VITAMIN SHOWN TO SLOW AGING PROCESS OVER 4-YEAR PERIOD

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1. Vitamin D could slow the aging process

A study by researchers at Mass General Brigham and the Medical College of Georgia discovered that taking vitamin D supplements may protect against biological aging.

Research published in The American Journal of Clinical Nutrition in May 2025 found that supplementing with daily vitamin D3 can reduce biological wear and tear equivalent to nearly three years of aging.

Vitamin D3 supplementation can reduce biological wear and tear equivalent to nearly three years of aging, research has shown. (iStock)

Three months later, researchers at Harvard confirmed this correlation with their own study published in the same journal.

Daily vitamin D3 supplementation was found to prevent the shortening of telomeres, the protective ends on chromosome strands, which is a hallmark of aging.

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2. Meditation practices may boost longevity

An April 2025 study by Maharishi International University (MIU), the University of Siegen, and the Uniformed Services University of the Health Sciences found that transcendental meditation can significantly alleviate stress and slow down aging.

The long-term meditation practice involves silently repeating a mantra in your head to achieve deep relaxation.

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The study, published in the journal Biomolecules, found that participants who practiced transcendental meditation had lower expression of the genes associated with inflammation and aging.

“These results support other studies indicating that the transcendental meditation technique can reverse or remove long-lasting effects of stress,” co-author Kenneth Walton, a senior researcher at MIU, previously told Fox News Digital. “Lasting effects of stress are now recognized as causing or contributing to all diseases and disorders.”

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Those who practiced transcendental mediation had a lower expression of genes associated with aging. (iStock)

3. GLP-1s are linked to reduction in mortality

A September 2025 study discovered that GLP-1 drugs, which are designed for diabetes and weight loss, could significantly reduce mortality for Americans.

Researchers at Swiss Re, a reinsurance company in Zurich, Switzerland, estimated that GLP-1 drugs could lead to a 6.4% reduction in all-cause mortality in the U.S. by 2045. In the U.K., more than a 5% reduction in mortality was projected over the same 20 years.

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Obesity is one factor that has “stalled progress in life expectancy,” as it is linked to 70% of the leading causes of death in high-income countries, according to the researchers.

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4. Creativity and socialization could extend lifespan

In October 2025, various research investigated the impact of social engagement on longevity.

A study published in the journal Brain, Behavior and Immunity found that social relationships can slow cellular aging.

A September 2025 study discovered that GLP-1 drugs could significantly reduce mortality for Americans. (iStock)

Researchers at Cornell University explored the long-term benefits of social connections on biological aging.

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“We found that strong social ties can literally slow down the biological aging process,” lead study author Anthony Ong previously said in an interview with Fox News Digital. “Strong social ties appear to work in the background over many years, building a more resilient body by reducing the chronic, low-grade inflammation that is a key driver of accelerated aging.”

Social connection is a major player in extending longevity, research has shown. (iStock)

A similar study was published the same month, revealing that creative activities such as music, dance, painting and even certain video games may help keep the brain biologically younger.

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Researchers from 13 countries — including teams at Trinity College Dublin in Ireland and SWPS University in Poland — analyzed brain data from more than 1,400 adults of all ages worldwide. Those who regularly pursued creative hobbies had brain patterns that appeared younger than their actual age.

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Even short bursts of creative activity, such as a few weeks of strategy-based video gaming, had noticeable benefits.

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Fox News Digital’s Deirdre Bardolf and Melissa Rudy contributed reporting.

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.

That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.

The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.

LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS

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Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).

Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.

The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.

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“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”

Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.

HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS

In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.

For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)

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The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.

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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”

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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.

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Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)

“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.

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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.

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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs


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What Is Zepbound? Weight-Loss Benefits, Costs and Dosage




















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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION

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Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

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The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

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New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities. 

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment. 

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

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