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Research Has Unveiled How Many Sets You Need to Do to Build Muscle

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Research Has Unveiled How Many Sets You Need to Do to Build Muscle

New evidence has shed light on the optimal amount of sets we need to be getting through in our workouts in order to build muscle.

Until this point, various studies have suggested that muscle gain will increase as volume increases, with different muscle groups requiring different amounts of sets for optimal muscle growth. However, it hasn’t been studied to the same extent as this particular piece of research.

In a YouTube video shared by Dr Mike Israetel, who holds PhD in Sport Physiology, and sport scientist PhD Dr Milo Wolf, the two experts discussed the findings of the study which was published in Medicine & Science in Sports and Exercise.

Focusing on the quadriceps and trained squats, leg presses and leg extensions, the study compared three training volumes:

  • Group 1 (Low Volume): 22 sets of quad training per week, split evenly over 2 workouts.
  • Group 2 (Medium Volume): 22 sets of quad training, adding 4 sets of weekly quad training every 2 weeks, resulting in 42 sets per week. This was 32 sets per week on average for the 12-week study.
  • Group 3 (High Volume): 22 sets of quad training, adding 6 sets of weekly quad training every 2 weeks, resulting in 52 sets per week. This was 38 sets per week on average for the 12-week study.

The results found that the high volume group (52 sets per week, 38 on average) resulted in greater muscle thickness and size as well as an improvement in strength gains. The study concluded that progressively adding four or six sets per week every two weeks elicited greater lower body strength and size over the 12 weeks.

Does this mean we should be completing 52 sets per week? The experts said it’s unlikely. Linking this study back to our training, it’s suggested that we could increase hypertrophy and strength by completing more than 22 sets a week. This could be achieved by adding 4-6 sets per week. However, that’s not as simple as it may seem.

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The study also mentioned that the limited certainty of the findings warrants caution due to the variation between results. For example, in the groups there were quite wide differences in results between participants. It’s also important to add that in this study, the participants were training extremely hard.

To put this into context, the high volume group completed 26 sets of quads with 2 minutes rest. The programme contained:

  • 9 sets of squats
  • 9 sets of leg press
  • 8 sets of leg extension

It’s pretty brutal to say the least, not to mention how much time this would take. A 30-minute lunch break workout this ain’t.

MH says: Not everyone can add more volume to their training, especially to this degree and with every single muscle group. Doing so would likely sacrifice adequate recovery and therefore increase the risk of injury, so of course work within your limitations.

The key takeaway is that despite this study’s findings, you don’t have to work to such high levels as 52 sets per week. However, you could focus on increasing weekly volume from where you are now and ensure you are working close to failure at the end of those sets.

How Many Sets for Building Muscle?

As a rule of thumb work 0-5 reps from failure, with an amount of sets suitable for your experience level.

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Referring to a more recent systematic review, it found:

If you want to absolutely maximise muscle growth: 30-40 sets would deliver the best results, but it’s important to note that above this point isn’t for everyone. 10-20 sets would be a more realistic goal.

This could look like:

  • 3-6 sets close to failure for a particular muscle group per workout, working on the basis that you train 3 times a week.

You could start here and increase weekly sets gradually as you get stronger and more acclimatised to the amount of work. The most important variable is to train with intensity on a consistent basis.

Using the new research as well as taking an individualised approach to your programming will likely improve your muscle gains, without you needing to skip the stairs.

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Quarantine Fitness Trends & Top Exercises During COVID-19

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How to stay active and motivated during quarantine

When your daily routines are disrupted, finding the motivation to exercise can be a challenge. The key is to build a new structure that works for you. Schedule your workouts as you would any important appointment to create commitment and turn intention into action.

Focus on consistency rather than intensity, especially when adapting to a new environment. Setting small, achievable goals—like a 20-minute walk or a short bodyweight circuit—can build momentum. Remember that any movement is better than none, and establishing a regular habit is the most important first step.

At-home and outdoor exercise ideas

You don’t need a fully equipped gym to maintain your fitness. Many effective workouts can be done with minimal or no equipment, either in your home or safely outdoors.

  • Bodyweight training: Exercises like squats, push-ups, lunges, and planks are foundational movements that build strength using your own body as resistance.
  • Yoga and mobility: Focusing on flexibility and movement quality can reduce stress and improve recovery. Many free resources are available for guided yoga flows and mobility routines.
  • Outdoor cardio: If you can do so safely, activities like walking, running, or cycling are excellent for cardiovascular health and provide a much-needed change of scenery.

The most popular quarantine exercises, according to WHOOP data

A recent study examined data from 50,000 WHOOP members between January 1 and May 15, including over 4.9 million workouts. This comparison captured exercise behaviors before and during social distancing, using March 9 as the cutoff—the week the World Health Organization classified COVID-19 as a pandemic and the US declared a national state of emergency.

The study tracked the six most popular exercises: running, functional fitness, weightlifting, cycling, swimming, and walking. It measured the relative frequency of each activity on a daily basis. As you can see in the graphic below, there was a significant uptick in running, cycling, and walking once social distancing began.

QUARANTINE EXERCISE MODALITIES WITH BIGGEST INCREASE

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Walking took the biggest jump, followed by running and cycling. The spikes on the graph show increased participation in all three activities on weekends, which continued during quarantine. However, with running in particular, the frequency of weekday and weekend participation became more similar—a lack of commuting gave runners more opportunity to get outside during the week.

The quarantine workouts that decreased

The three activities people started doing more of are all individual forms of exercise that happen outdoors—a needed break from being stuck inside. Functional fitness, which for many members was already a solo at-home workout, saw little change. Weightlifting and swimming saw significant decreases, coinciding with the closures of gyms and athletic facilities.

Other trends in quarantine exercise: Increased frequency and intensity

The sample of 50,000 WHOOP members exercised 1.1% more often once quarantine began. With many social activities unavailable, people turned to working out to pass the time. Exercise modalities like running and cycling require a high cardiovascular load, and members spent 1.8% more time working out in their three highest heart rate zones during quarantine.

The study also discovered improvements in several key physiological markers that WHOOP tracks, including sleep, resting heart rate, and heart rate variability.

Understand your body’s response to new routines

Adapting your fitness routine is the first step. Understanding how your body responds to those changes is the next. Are your new workouts building fitness without compromising recovery, and are you getting enough sleep to support your efforts?

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WHOOP quantifies the impact of your daily behaviors on your body. By monitoring your Sleep, daily Strain, and Recovery, you get personalized insights to help you train smarter, recover faster, and build healthier habits.

Frequently asked questions

Does exercise help fight a virus?

Regular, moderate exercise can support your immune system. Physical activity helps promote good circulation, which allows the cells and substances of the immune system to move through the body freely and do their job efficiently. However, it’s important to balance activity with recovery, as overtraining can place stress on the body.

Does exercise speed up COVID-19 recovery?

The relationship between exercise and COVID-19 recovery is complex and depends on the individual. Some research suggests that light physical activity during and after the illness may help with certain symptoms, particularly mental and neurological ones. It is critical to listen to your body, avoid strenuous activity while sick, and consult with a healthcare professional before resuming exercise after an infection.

How does WHOOP measure the intensity of a workout?

WHOOP measures the intensity of your activities by analyzing your heart rate. The Strain score quantifies the total cardiovascular load you experience throughout the day, whether from a specific workout or other daily stressors. By tracking how much time you spend in elevated heart rate zones, WHOOP gives you a clear picture of how hard your body is working.

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I’m a fitness writer and these are the 44 best deals I’ve found in the Amazon Big Spring Sale

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I’m a fitness writer and these are the 44 best deals I’ve found in the Amazon Big Spring Sale

Lou Mudge is a Health Writer at Future Plc, working across Fit&Well and Coach. She previously worked for Live Science, and regularly writes for Space.com and Pet’s Radar. Based in Bath, UK, she has a passion for food, nutrition and health and is eager to demystify diet culture in order to make health and fitness accessible to everybody.

Multiple diagnoses in her early twenties sparked an interest in the gut-brain axis and the impact that diet and exercise can have on both physical and mental health. She was put on the FODMAP elimination diet during this time and learned to adapt recipes to fit these parameters, while retaining core flavors and textures, and now enjoys cooking for gut health.

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Exercise scientist reveals the strength training mistake many women make, even after lifting for years

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Exercise scientist reveals the strength training mistake many women make, even after lifting for years

Wondering how much weight you should be lifting in the gym to build strength? Dr Stacy Sims says that not going heavy enough could be the biggest mistake women are making in their workouts.

What strength training looks like might differ (for example, some prefer callisthenics over classic weight training) for some, but one thing is clear – it needs to be a challenge.

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