Health
Fatal drug combination sparks alert as ‘rhino tranq’ spreads across US
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Health and government officials are warning of a potential deadly substance in the illegal drug supply.
The Centers for Disease Control and Prevention (CDC) and the White House Office of National Drug Control Policy (ONDCP) issued a health advisory on Thursday about reports of medetomidine being detected in fentanyl.
Also known as “rhino tranq,” “mede” or “dex,” medetomidine is a veterinary sedative that causes severe, prolonged sedation. Classified as an alpha-2 agonist, it acts on the nervous system similar to other veterinary sedatives, like xylazine, and can cause life-threatening withdrawal symptoms.
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The advisory is based on surveillance data, including forensic drug testing, wastewater analysis, clinical case reports and overdose investigations.
In 2023, there were 247 incidences of medetomidine detected in drug samples, which rose to 2,616 in 2024 and 8,233 in 2025 – a more than 3,000% increase. Forensic drug reports showed that about 98% of medetomidine-positive samples also contained fentanyl.
Health and government officials are warning of a potential deadly substance in the illegal drug suppl (iStock)
The drug has been detected in at least 18 states and Washington, D.C., with a concentration in the Northeast and Midwest regions of the U.S., per the CDC alert.
Dr. Adam Scioli, chief medical officer of Caron Treatment Centers in Pennsylvania, said the alert highlights a “concerning and rapidly evolving development” in the illicit opioid supply.
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“Its co‑occurrence with fentanyl significantly complicates overdose presentation and withdrawal management, further increasing both clinical acuity and unpredictability,” he told Fox News Digital.
“Medetomidine is not routinely detected on standard toxicology screens, increasing the risk of under‑recognition without a high index of clinical suspicion.”
The drug has been detected in at least 18 states and Washington, DC, with a concentration in the Northeast and Midwest regions of the U.S. (iStock)
Naloxone (Narcan), known for its overdose reversal effects, does not counteract medetomidine, the advisory warned.
“While naloxone remains essential for reversing opioid‑induced respiratory depression, it does not address the sedative effects of medetomidine,” Scioli confirmed.
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The initial effects of the drug include deep sedation or decreased consciousness, bradycardia (slow heart rate), hypotension (low blood pressure) and respiratory depression, especially when combined with fentanyl and other opioids.
Withdrawal symptoms typically begin about a few hours after taking medetomidine. They can be severe and rapid, peaking at about 18-36 hours, according to experts.
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Initial withdrawal symptoms include rising blood pressure, tachycardia, agitation and nausea/vomiting, gradually leading to severe hypertension, altered mental status, and possible cardiac or neurologic complications, per the alert.
Severe cases require intensive care in a hospital. “Management may require ICU‑level monitoring and care,” said Scioli.
Naloxone (Narcan), known for its overdose reversal effects, does not counteract medetomidine, the advisory warned. (Reuters/Andrew Kelly)
In a May 2024 example cited by the CDC, medetomidine in the illegal opioid supply was linked to a cluster of overdoses in Chicago, potentially exceeding 175. At least 16 people were hospitalized and one died.
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There were some limitations to the surveillance, the agency acknowledged. Surveillance systems rely on small samples that may not be representative of all areas.
There is also the chance that the numbers could be overestimated due to contamination or repeated use of drug paraphernalia. Conversely, numbers could actually be higher than recorded, as medetomidine is rapidly metabolized in the body and is not typically tested in clinical settings.
An expert noted that the alert highlights the need for “careful assessment beyond standard opioid toxicity models,” as well as close coordination with toxicology, emergency medicine and public health partners. (iStock)
The surveillance was conducted by the CDC with support from federal public health programs and collaboration with other agencies.
Scioli noted that the alert highlights the need for “careful assessment beyond standard opioid toxicity models,” as well as close coordination with toxicology, emergency medicine and public health partners.
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“The drug supply is evolving in ways that strain traditional opioid‑focused frameworks and demand greater clinical vigilance,” he said.
“From a treatment perspective, this is another clear example of why addiction care must be adaptive, medically sophisticated, and grounded in whole‑person, long‑term recovery — not solely acute stabilization,” he added.
Health
This everyday drinking pattern could quietly raise liver disease risk
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Top stories
→ Widespread drinking habit could triple risk of advanced liver condition
→ Deadly bacterial disease could be stopped by pantry staple
→ Common vaccine slashes Alzheimer’s disease risk when dose is increased
Even occasional binge drinking could triple the risk of a serious liver condition, a new study suggests. (iStock)
On the lookout
→ 5 key factors may predict stroke risk years after first event
→ Unexplained shoulder pain could signal dangerous health condition
→ Experts reveal hidden link between poor sleep and Alzheimer’s disease
Monica Deyanira Cabrera Barajas, 26, underwent a 20-minute extraction that turned into a high-stakes medical procedure. (Jam Press)
Conversation starters
→ Woman swallows nose ring, finds it traveled to her lungs
→ Divorce boom may follow use of Ozempic and other GLP-1 drugs
→ Drug-soaked paper is killing inmates amid reports of prison smuggling
On the table
→ Popular food additive linked to higher health risks in adults over 60
→ One simple eating habit may help boost weight loss
→ Hospital food could be harming America’s sickest patients
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Health
Common vaccine slashes Alzheimer’s disease risk when dose is increased
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A new, stronger flu shot could slash Alzheimer’s risk in half, according to new data.
The study, led by researchers at the University of Texas Health Science Center at Houston (UTHealth), found that adults 65 and older who received a high-dose influenza vaccine had a significantly lower risk of developing Alzheimer’s disease compared to those who received the standard dose.
The immune system naturally weakens with age, making older adults less responsive to standard vaccines. To combat this, the Centers for Disease Control and Prevention recommends a high-dose flu vaccine for people over 65. This version is approximately four times stronger than the standard shot.
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Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older.
Dr. Marc Siegel, a Fox News senior medical contributor, weighed in on the impact of the flu shot on Alzheimer’s risk.
Alzheimer’s disease, a brain disorder that slowly destroys memory and thinking skills, affects more than 6 million Americans, most of them age 65 or older. (iStock)
As the vaccine directly affects the immune system, it is possible that this interaction could decrease inflammation in the body and “thereby indirectly decrease Alzheimer’s risk,” Siegel, who was not involved in the research, told Fox News Digital.
“Flu shots and their components do not cross the blood-brain barrier, meaning they aren’t directly affecting brain cells.”
“We can’t conclude from this that it is the flu shot itself that causes the effect.”
“I was stunned that, as a physician, I didn’t know a higher dose was offered,” lead study author Paul Schulz, professor of neurology at McGovern Medical School at UTHealth, said in a press release.
Schulz also led a previous study linking general flu vaccination to a 40% reduction in Alzheimer’s risk.
While the previous research had already linked general flu vaccination to a reduction in Alzheimer’s risk, this new study looked specifically at the strength of the dose.
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“The public health department had seen our vaccine research and asked if I could come down to talk to them about it,” said Schulz. “We went through the findings, and they asked if there was a difference with different dosages; I was confused.”
Adults who received the quadruple-strength vaccine had a lower risk of Alzheimer’s than those who received the standard dose. (iStock)
After sorting through data from nearly 200,000 older adults, the team found the adults who received the high-dose vaccine had a lower risk of Alzheimer’s than those who received the standard dose.
Adults in the high-dose group had an almost 55% lower risk than those who weren’t vaccinated, significantly outperforming standard-dose protection.
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The protective effect of the high-dose vaccine was even more pronounced in women compared to men, although both groups saw significant benefits.
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This study shows a link, not a cause, the researchers noted.
Experts can’t say for certain that the flu shot itself stopped Alzheimer’s because people who get high-dose vaccines might also have other healthy habits, like better diets or more frequent check-ups.
The study focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection. (iStock)
The researchers also looked at medical records after the fact, rather than following two controlled groups in real time, which can sometimes result in missing information or biases.
“This is not a cause/effect study,” Siegel reiterated. “We can’t conclude that the flu shot itself causes the effect; it could be something about the people who decide to take this shot.”
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The study also focused on people over 65, so it’s unclear whether getting these shots earlier in life would provide the same level of protection.
“This needs to be further studied, but it is already certainly another reason to take a flu shot,” Siegel added.
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The study was published in the journal Neurology.
Health
Woman discovers missing nose ring traveled to her lungs, causing month-long cough
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A TikToker in Mexico thought her cough that wouldn’t go away was just a reaction to the changing weather. Instead, it was her own nose ring, lodged deep within her lungs.
The 26-year-old, Monica Deyanira Cabrera Barajas, recently went viral on TikTok, amassing 4.7 million views after revealing the freak medical accident.
In videos, she shared that the stray accessory sat a mere 0.5 millimeters from her aorta, Jam Press reported.
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Deyanira, who has a large number of piercings, didn’t initially notice the jewelry was missing. It wasn’t until she developed a “chronic cough” lasting over a month that she went to see a doctor.
“The only theory I have, which I told the pulmonologist, is that I fell asleep, the little ball fell out, and that was it,” Deyanira told creatorzine.com.
What was supposed to be a routine 20-minute extraction turned into a high-stakes medical procedure. (Jam Press)
“I was lying on my back, I didn’t realize, and that’s how I messed up.”
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What was supposed to be a routine 20-minute extraction turned into a high-stakes medical procedure. During the initial attempt, surgeons were unable to budge the object because it had already begun attaching to her internal tissue.
“It ended up taking an hour and 20 minutes, and they still couldn’t remove it because it was attached to my body,” she said, according to the Jam Press report.
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Facing a second, more invasive surgery and the risk of a fatal hemorrhage, Deyanira prepared for the worst. The night before the surgery, she wrote a farewell letter to her loved ones.
The nose ring was lodged dangerously close to her aorta, the body’s primary artery. (Jam Press)
“I was honestly thinking, ‘I’m going to die,’” she said. “It’s a horror I wouldn’t wish on anyone.”
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The woman’s surgeon was equally stunned by how close the metal was to her heart. According to Deyanira, the doctor told her, “It seems God takes care of his creatures.”
If the metal had punctured her lung or heart before doctors discovered it, Deyanira said she likely would have died from a lung collapse or perforated aorta.
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Now, the TikToker says her days of septum rings are over.
After the ordeal, Deyanira said she’s permanently done with piercings. (Jam Press)
“I love piercings, and I really liked my septum piercing, but in my case, I wouldn’t get it again because of the terror I experienced,” she said.
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Followers commented that the ordeal “unlocked a fear I didn’t know I had.”
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