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Men face hidden heart risk years earlier than women, study suggests

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Men face hidden heart risk years earlier than women, study suggests

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Men are at a much higher risk of heart attacks than women earlier in life, a new study reveals.

Researchers at Northwestern University found that men start to develop coronary heart disease years earlier than women, with differences emerging as early as the mid-30s, according to a press release.

The study, published in the Journal of the American Heart Association (JAHA), analyzed data from more than 5,000 adults, aged 18 to 30, from the mid-1980s through 2020, as part of the Coronary Artery Risk Development in Young Adults (CARDIA) analysis.

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Men reached a 5% incidence of cardiovascular disease, including heart attack, stroke and heart failure, at around 50 years old compared to 57 for women.

Coronary heart disease, which is when blood vessels that supply the heart muscle become narrowed or blocked, was the main driver of the difference, as men reached a 2% incidence more than a decade before women. Stroke and heart failure emerged later in life.

Heart disease risk among men rises faster at around 35 years of age, research finds. (iStock)

Men’s risk began rising faster at around age 35 and remained high throughout midlife, according to the research. Everyone in the study was under 65 years old at the last follow-up. 

Current guidelines generally recommend cardiovascular risk assessment beginning around age 40, which some experts say may miss an important window for early prevention.

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Heart disease develops over decades, with early markers detectable in young adulthood, according to senior study author Alexa Freedman, assistant professor of preventive medicine at Northwestern University Feinberg School of Medicine.

Lifestyle factors are most likely the main driver of cardiovascular events in men, a cardiologist suggests. (iStock)

“Our findings highlight the importance of promoting heart health screening and prevention in young adulthood, especially for young men,” Freedman told Fox News Digital.

The researchers emphasized the importance of looking beyond standard measures of heart risk, like cholesterol or blood pressure, and considering a “broader range of biological and social factors.”

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Dr. Andrew Freeman, cardiologist and director of clinical cardiology at National Jewish Health in Denver, was not involved in the study but commented on the findings.

“We have always known that men tend to manifest and typically die earlier from things like heart attacks and strokes compared to women,” he told Fox News Digital.

The lead researcher recommends more frequent or early CT angiograms to help prevent cardiac events. (iStock)

Although the study did not identify why more men are predisposed to heart issues than women, Freeman said factors like hormonal differences, diet and physical activity could come into play. 

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“The standard American lifestyle makes us all sick, and then men seem to be more prone to developing this disease earlier,” the cardiologist told Fox News Digital. 

“We are more exposed to toxins than ever before in virtually every part of our food supply,” he added. “We already know well that air pollution, light pollution and sound pollution are all associated with earlier heart disease.”

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Americans are also more sedentary, get less sleep, are more stressed and are less socially connected, all of which can increase cardiovascular diseases, Freeman added.

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“I think this study is really underscoring that it’s time for some big changes,” he said.

Regular daily exercise is one way to set up your heart for a long life, experts agree. (iStock)

The doctor shared the following five “healthspan” tips to help prevent heart health issues.

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  1. Limit toxin exposure in the form of alcohol, tobacco, marijuana, nicotine and air pollution
  2. Eat a predominately low-fat, whole-food, plant-based diet
  3. Exercise regularly, ideally 20 to 30 minutes every day at a level of breathlessness (with sign-off from a doctor)
  4. Partake in stress-relieving activities and mindfulness exercises
  5. Get adequate, uninterrupted sleep
  6. Cultivate a strong support network of friends and family

“We need to do everything we can to clean up our lifestyles and reduce our disease burden.”

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Freeman also recommends addressing any comorbidities, like high blood pressure, high cholesterol and obesity.

Those at a higher risk of cardiovascular events may want to consider earlier screening, although Freeman suggested that early prevention efforts should apply to everyone.

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“Coronary disease is manifesting earlier than ever here in the U.S., and we need to do everything we can to clean up our lifestyles and reduce our disease burden,” he said. “If you’re a man, you’ve got to be extra aggressive earlier in life.”

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Common nighttime noise exposure may trigger heart problems, study suggests

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Common nighttime noise exposure may trigger heart problems, study suggests

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Living near heavy traffic could negatively impact your heart health.

A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.

The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.

Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.

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Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)

The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.

Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.

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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.

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The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”

Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)

Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”

SIMPLE NIGHTLY HABIT LINKED TO HEALTHIER BLOOD PRESSURE, STUDY SUGGESTS 

“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.

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“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”

This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.

“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)

“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”

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The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”

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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”

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The researcher noted that these findings were consistent across genders, education levels and obesity status.

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The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.

Changes in cholesterol levels were more severe than researchers expected. (iStock)

“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”

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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.

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“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”

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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”

Experts recommend taking measures to limit traffic noise at night. (iStock)

Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”

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“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”

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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.

“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.

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‘SuperAgers’ stay mentally sharp well past 80, as scientists reveal the reason

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