Health
Common spice may beat depression and boost sexual health, doctor says
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One specific spice could function as a natural antidepressant, an expert says.
Saffron, found in popular foods and drinks like paella and herbal teas, has shown promise for its ability to boost mood and reduce symptoms of depression, in addition to other various health benefits.
During an in-studio interview with Fox News Digital, Dr. Daniel Amen, psychiatrist and founder of Amen Clinics in California, shared his enthusiasm about using saffron for mental health support.
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“I love saffron so much,” he said. “I’m Lebanese, and Middle Eastern folks cook with a lot of saffron. And there’s actually folklore in Iran: If you’re too happy, you must have had saffron.”
Amen referenced research showing that about 30 milligrams of saffron was “equally as effective” as antidepressants in randomized trials.
Saffron may increase sexual function, unlike traditional SSRIs, according to Dr. Amen. (iStock)
While most SSRIs (selective serotonin reuptake inhibitors) can help boost mood, they also pose the risk of decreasing sexual function. Saffron does the opposite, according to Amen.
“As a psychiatrist, I don’t want to ruin my patients’ love lives,” he said. “Saffron increased sexual function [in research].”
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Saffron has also been shown to help with memory and focus, according to various studies.
A recent study, published in Reviews in Clinical Medicine 2025, also linked saffron to decreased symptoms of premenstrual syndrome (PMS).
Research has shown that saffron can boost mood and improve PMS symptoms. (iStock)
After eight to 12 weeks of saffron use, participants reported that the supplement “significantly reduced” the symptoms and severity of PMS.
Additional research published in the Cambridge University Press in May 2025 revealed saffron’s potential to ease depression symptoms.
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The review analyzed 192 trials involving more than 17,000 patients and 44 different nutraceuticals to determine which supplements work for depression.
Saffron was identified as most effective, showing a moderate to large antidepressant effect.
Saffron is found in a variety of dishes, including paella and rice variations. (iStock)
The meta-analysis also examined how these nutraceuticals interacted with prescribed antidepressant medications.
Combining supplements like zinc and curcumins (natural compounds found in turmeric) with existing antidepressants were found to improve symptoms.
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“So, if you’re on an antidepressant and you want it to work even better, think about zinc and curcumins,” Amen recommended. “Saffron, zinc and curcumins is a great combination.”
Saffron is often consumed as a supplement in pills, capsules or powders. (iStock)
While cooking with saffron may not achieve the levels needed to improve mood, saffron supplements are available as capsules, tablets and powdered extract. Thirty milligrams per day is typically the recommended dose for symptom relief.
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Long-term use of saffron has yet to be studied, as there is some uncertainty around its potency as a supplement, researchers and experts have warned.
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According to a medically reviewed WebMD article, taking saffron in high doses or for long periods of time “may be risky,” potentially causing anxiety, appetite changes, upset stomach sleepiness or headache.
Anyone interested in starting a saffron supplement should first consult with a doctor.
Health
Common nighttime noise exposure may trigger heart problems, study suggests
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Living near heavy traffic could negatively impact your heart health.
A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.
The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.
Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)
The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.
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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.
The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”
Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)
Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”
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“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.
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“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”
This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.
“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)
“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”
The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”
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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”
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The researcher noted that these findings were consistent across genders, education levels and obesity status.
The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.
Changes in cholesterol levels were more severe than researchers expected. (iStock)
“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”
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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.
“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”
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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”
Experts recommend taking measures to limit traffic noise at night. (iStock)
Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”
“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”
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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.
“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.
Health
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Health
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