Health
Hair-loss drug tied to suicides, depression and anxiety in global study
NEWYou can now listen to Fox News articles!
This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).
Millions of men undergoing hair loss treatment may be putting their mental health on the line.
Finasteride, a hair-loss drug prescribed for androgenetic alopecia, the most common form of baldness, has been linked to a higher risk of suicide in global studies.
A recent review by Mayer Brezis, a professor at the Hebrew University of Jerusalem, which was published in The Journal of Clinical Psychiatry, argues that there is now enough evidence to mark depression, anxiety and suicidality as genuine risks of the drug.
POPULAR BACK PAIN MEDICATION LINKED TO BRAIN HEALTH RISKS IN SOME PATIENTS
Finasteride has been linked to depression and suicide for more than 20 years, Brezis revealed, calling attention to the lack of action from manufacturers and regulators.
These concerns were raised in several studies as early as 2002. Four independent analyses and four studies indicating a “significant increase” in depression, anxiety and suicidal behavior were released between 2017 and 2023.
Multiple global studies have linked finasteride with an increase in depression, anxiety and suicidal behavior. (iStock)
“There has been, therefore, a two-decade delay in the realization of the incidences and the gravity of neuropsychiatric effects, allowing harm from a medicine prescribed for a cosmetic indication of hair loss,” the author wrote in the study.
“Over 20 years worldwide, hundreds of thousands may have endured depression, and hundreds may have died by suicide.”
Finasteride users have reported ongoing symptoms even after the drug is stopped, including insomnia, panic attacks, cognitive dysfunction and suicidal thoughts.
NEW STEM CELL THERAPY SHOWS ‘PROMISING’ RESULTS FOR TREATING HAIR LOSS IN PRECLINICAL TRIALS
In a Hebrew University of Jerusalem press release, Brezis reiterated that the evidence of this connection is “no longer anecdotal.”
“We now see consistent patterns across diverse populations. And the consequences may have been tragic,” he said.
Finasteride is a hair-loss drug prescribed for androgenetic alopecia. (iStock)
“The lesson is that before approving a medication for the market, regulators should require manufacturers to commit to performing and disclosing ongoing post-approval analytical studies, and this requirement needs to be enforced,” Brezis concluded in the review.
In 2011, the FDA reportedly acknowledged depression as a potential side effect of finasteride, adding suicidality in 2022.
The agency recorded 18 suicides linked to finasteride in 2011, although Brezis argued that the number should have “ranged in the thousands.”
In an additional statement sent to Fox News Digital, Brezis confirmed that physicians frequently prescribe finasteride “offhandedly because they are not aware of its risks.”
“My recommendation to patients and physicians: Stay away from this medication,” the researcher said. (iStock)
“Young people often get it from the internet without realizing it can cause anxiety, depression and even suicidal thoughts, in addition to sexual impairment,” he said. “Unfortunately, these adverse effects may persist after discontinuing the medication.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
“My recommendation to patients and physicians: Stay away from this medication,” he said. “My recommendation to the FDA: Take it off the market.”
Finasteride was reportedly invented by biopharmaceutical company Merck, which manufactures the drug under the brand names Proscar and Propecia. Other companies produce generic finasteride versions.
“Organon stands behind the safety and efficacy of its finasteride products.”
Organon, formerly part of Merck, is the manufacturer of Propecia and Proscar, two finasteride products. The company provided the below statement to Fox News Digital.
“Organon stands behind the safety and efficacy of its finasteride products. Regulatory agencies around the world thoroughly reviewed the safety and efficacy data for these medicines before their approval, and they, together with Organon, have continued to review additional safety and efficacy data in the decades that these products have been on the market as part of the rigorous, routine post-marketing surveillance process.”
The company encourages patients to speak with their doctors if they have any questions or concerns about their health or medication.
For more Health articles, visit www.foxnews.com/health.
A spokesperson for the U.S. Department of Health and Human Services also weighed in on the findings in a statement to Fox News Digital.
“The FDA advises patients to discuss the potential risks and benefits with their healthcare providers before using any pharmaceutical product,” the statement read. “This is particularly important as the FDA has not approved any topical finasteride products, which have been associated with numerous adverse effects reported to the agency.”
Health
Loneliness may be silently eroding your memory, new research reveals
NEWYou can now listen to Fox News articles!
Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
GRANDPARENTS WHO BABYSIT THEIR GRANDCHILDREN STAY MENTALLY SHARPER, NEW STUDY REVEALS
“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
EXPERTS REVEAL HIDDEN LINK BETWEEN POOR SLEEP AND ALZHEIMER’S DISEASE RISK
The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
DEMENTIA RISK SIGNALS COULD LIE IN SIMPLE BLOOD PRESSURE READINGS, SAY RESEARCHERS
Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
CLICK HERE FOR MORE HEALTH STORIES
“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
Health
Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
Health
Intermittent fasting’s real benefit may come after you start eating again
NEWYou can now listen to Fox News articles!
Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
POPULAR INTERMITTENT FASTING DIETS MAY NOT DELIVER THE HEALTH BENEFITS MANY EXPECT
The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
PEOPLE LOST WEIGHT WHILE EATING SIGNIFICANTLY MORE FOOD — HERE’S THE SECRET
“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
CLICK HERE FOR MORE HEALTH STORIES
Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
-
Fitness4 minutes agoI’m a running coach — I’ve just tested shoes actually designed for women’s feet, and they’re a total game changer
-
Movie Reviews16 minutes ago‘Hen’ movie review: György Pálfi pecks at Europe’s migrant crisis through the eyes of a chicken
-
Business46 minutes agoVideo: Why Your Paycheck Feels Smaller
-
Culture1 hour agoFamous Authors’ Less Famous Books
-
Lifestyle1 hour agoSunday Puzzle: For Mimi
-
Technology1 hour agoThe future of local TV news has taken a Trumpian turn
-
World2 hours agoPope Leo says remarks about world being ‘ravaged by a handful of tyrants’ were not aimed at Trump: report
-
Politics2 hours agoTrump renews bridge, power plant threat against Iran in push for deal, mocks ‘tough guy’ IRGC